Rick Fandino, PhD (He/Him/él)
@hwkmthcrspr.bsky.social
Olfaction | Functional Genomics and Systems Biology in Lepidoptera | evodevo | epigenomics | development | ADHD | 1stGEN | #diversityinSTEM #latinxinSTEM #LGBTQ+inSTEM
Reposted by Rick Fandino, PhD (He/Him/él)
🦟 Pestered by mosquitoes? Fear not—grapefruit might hold the key! 🍊In our latest paper in @currentbiology.bsky.social, led by Merybeth Triana and Felipe Andreazza, we explore how nootkatone, a compound derived from grapefruit, affects mosquitoes. authors.elsevier.com/sd/article/S...
December 3, 2024 at 9:18 PM
🦟 Pestered by mosquitoes? Fear not—grapefruit might hold the key! 🍊In our latest paper in @currentbiology.bsky.social, led by Merybeth Triana and Felipe Andreazza, we explore how nootkatone, a compound derived from grapefruit, affects mosquitoes. authors.elsevier.com/sd/article/S...
Reposted by Rick Fandino, PhD (He/Him/él)
www.nature.com/articles/s41...
(1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature
(1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature
Nucleosome fibre topology guides transcription factor binding to enhancers - Nature
Motif grammar on nucleosome fibres acts as signpost elements, directing TF combinatorial binding to enhancers.
www.nature.com
December 18, 2024 at 5:34 PM
www.nature.com/articles/s41...
(1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature
(1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature
Reposted by Rick Fandino, PhD (He/Him/él)
Check out new research by @lucalivraghi.bsky.social. I painted watercolor illustrations of Speyeria mormonia to show the differences in the silver coloration for use in their figures. Thank you @evolvwing.bsky.social and Luca for giving me the chance to paint some cool butterflies!
#sciart
#sciart
New preprint by butterfly wizard
@lucalivraghi.bsky.social
www.biorxiv.org/content/10.1...
We mapped optix (again?!) as the switch gene of a natural polymorphism, this time controlling silver patches of a mountain butterfly. Gorgeous RNAi validation, evidence of selective sweeps, introgression
@lucalivraghi.bsky.social
www.biorxiv.org/content/10.1...
We mapped optix (again?!) as the switch gene of a natural polymorphism, this time controlling silver patches of a mountain butterfly. Gorgeous RNAi validation, evidence of selective sweeps, introgression
December 18, 2024 at 7:44 AM
Check out new research by @lucalivraghi.bsky.social. I painted watercolor illustrations of Speyeria mormonia to show the differences in the silver coloration for use in their figures. Thank you @evolvwing.bsky.social and Luca for giving me the chance to paint some cool butterflies!
#sciart
#sciart
Reposted by Rick Fandino, PhD (He/Him/él)
Happy to share this new preprint looking at the genetic basis for a butterfly wing polymorphism. A fun story of genetic parallelism. Thoughts/comments welcome :)
New preprint by butterfly wizard
@lucalivraghi.bsky.social
www.biorxiv.org/content/10.1...
We mapped optix (again?!) as the switch gene of a natural polymorphism, this time controlling silver patches of a mountain butterfly. Gorgeous RNAi validation, evidence of selective sweeps, introgression
@lucalivraghi.bsky.social
www.biorxiv.org/content/10.1...
We mapped optix (again?!) as the switch gene of a natural polymorphism, this time controlling silver patches of a mountain butterfly. Gorgeous RNAi validation, evidence of selective sweeps, introgression
December 17, 2024 at 3:23 PM
Happy to share this new preprint looking at the genetic basis for a butterfly wing polymorphism. A fun story of genetic parallelism. Thoughts/comments welcome :)
Reposted by Rick Fandino, PhD (He/Him/él)
As I have a few followers now I figure I could post about some recent papers: @henrylnorth.bsky.social analysed sequence data from @theswordlab.bsky.social for North American Helicoverpa zea - we found just two individuals from 400 with introgressed armigera allele for insecticide resistance
Rapid Adaptation and Interspecific Introgression in the North American Crop Pest Helicoverpa zea
Abstract. Insect crop pests threaten global food security. This threat is amplified through the spread of nonnative species and through adaptation of nativ
academic.oup.com
December 10, 2024 at 6:49 PM
As I have a few followers now I figure I could post about some recent papers: @henrylnorth.bsky.social analysed sequence data from @theswordlab.bsky.social for North American Helicoverpa zea - we found just two individuals from 400 with introgressed armigera allele for insecticide resistance
Reposted by Rick Fandino, PhD (He/Him/él)
Tempo and mode of winter diapause evolution in butterflies
doi.org/10.1093/evle...
Now in @EvolLetters by Sridhar Halali, Etka Yapar, Christopher W Wheat, Niklas Wahlberg, Karl Gotthard, Nicolas Chazot, Sören Nylin, and Philipp Lehmann
doi.org/10.1093/evle...
Now in @EvolLetters by Sridhar Halali, Etka Yapar, Christopher W Wheat, Niklas Wahlberg, Karl Gotthard, Nicolas Chazot, Sören Nylin, and Philipp Lehmann
Tempo and mode of winter diapause evolution in butterflies
Abstract. Quantifying the tempo and mode via modern phylogenetic comparative methods can provide key insights into how selection and constraints shape trai
doi.org
December 9, 2024 at 8:57 PM
Tempo and mode of winter diapause evolution in butterflies
doi.org/10.1093/evle...
Now in @EvolLetters by Sridhar Halali, Etka Yapar, Christopher W Wheat, Niklas Wahlberg, Karl Gotthard, Nicolas Chazot, Sören Nylin, and Philipp Lehmann
doi.org/10.1093/evle...
Now in @EvolLetters by Sridhar Halali, Etka Yapar, Christopher W Wheat, Niklas Wahlberg, Karl Gotthard, Nicolas Chazot, Sören Nylin, and Philipp Lehmann
Reposted by Rick Fandino, PhD (He/Him/él)
Yeah this could be a game-changer for specimen-based color research. Ben Hogan and Cassie Stoddard present a pipeline combining whole-specimen image analysis with reflectance spectrophotometry. The only catch? The setup costs about $55k... 💰 doi.org/10.1371/jour...
December 6, 2024 at 4:46 PM
Yeah this could be a game-changer for specimen-based color research. Ben Hogan and Cassie Stoddard present a pipeline combining whole-specimen image analysis with reflectance spectrophotometry. The only catch? The setup costs about $55k... 💰 doi.org/10.1371/jour...
Reposted by Rick Fandino, PhD (He/Him/él)
Most proud of – I failed and failed, and failed again and again, four years of failure learning new methods, doing so many things wrong, using qRT-PCR for things it wasn't intended for, arguing that the cis-regulatory paradigm made no sense but eventually 🧪 🌱🐋
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
December 5, 2024 at 1:54 AM
Most proud of – I failed and failed, and failed again and again, four years of failure learning new methods, doing so many things wrong, using qRT-PCR for things it wasn't intended for, arguing that the cis-regulatory paradigm made no sense but eventually 🧪 🌱🐋
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Rick Fandino, PhD (He/Him/él)
When lunch consists of some yummy salty sweat from some nasty human's hand...
Catagramma pygas thamyras
Parque Nacional do Iguazú, Paraná, Brazil
Catagramma pygas thamyras
Parque Nacional do Iguazú, Paraná, Brazil
December 4, 2024 at 10:50 PM
When lunch consists of some yummy salty sweat from some nasty human's hand...
Catagramma pygas thamyras
Parque Nacional do Iguazú, Paraná, Brazil
Catagramma pygas thamyras
Parque Nacional do Iguazú, Paraná, Brazil
Reposted by Rick Fandino, PhD (He/Him/él)
Highly-respected non-profit journals like @dev-journal.bsky.social support scientific communities
But after rejection at glam journals, it is tempting to avoid re-review by sliding through commercial ecosystems
BUT WAIT! LOOK! “We will consider papers with reviewer reports from other journals” 😍
But after rejection at glam journals, it is tempting to avoid re-review by sliding through commercial ecosystems
BUT WAIT! LOOK! “We will consider papers with reviewer reports from other journals” 😍
December 3, 2024 at 9:33 AM
Highly-respected non-profit journals like @dev-journal.bsky.social support scientific communities
But after rejection at glam journals, it is tempting to avoid re-review by sliding through commercial ecosystems
BUT WAIT! LOOK! “We will consider papers with reviewer reports from other journals” 😍
But after rejection at glam journals, it is tempting to avoid re-review by sliding through commercial ecosystems
BUT WAIT! LOOK! “We will consider papers with reviewer reports from other journals” 😍
Reposted by Rick Fandino, PhD (He/Him/él)
Super stoked to share our latest research on the migratory patterns of painted lady butterflies across the Sahara! 🦋🏜️
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Trans-Saharan migratory patterns in Vanessa cardui and evidence for a southward leapfrog migration
Chemistry; Nature conservation; Ecology; Entomology
www.cell.com
December 3, 2024 at 9:02 PM
Super stoked to share our latest research on the migratory patterns of painted lady butterflies across the Sahara! 🦋🏜️
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by Rick Fandino, PhD (He/Him/él)
I just made a $500 donation to iNaturalist for #GivingTuesday because, well, iNaturalist is an incredible incredible resource and tool for the world www.inaturalist.org/donate.
Donate to iNaturalist
Donate now to show your support!
www.inaturalist.org
December 3, 2024 at 4:59 PM
I just made a $500 donation to iNaturalist for #GivingTuesday because, well, iNaturalist is an incredible incredible resource and tool for the world www.inaturalist.org/donate.
Reposted by Rick Fandino, PhD (He/Him/él)
Here's another extraordinary gynandromorph, of Pieriballia viardi, from Mexico. The right side is pure male, while the left side is all female except for the white areas, which are male.
Full data in alt text.
Full data in alt text.
November 28, 2024 at 1:15 AM
Here's another extraordinary gynandromorph, of Pieriballia viardi, from Mexico. The right side is pure male, while the left side is all female except for the white areas, which are male.
Full data in alt text.
Full data in alt text.
Reposted by Rick Fandino, PhD (He/Him/él)
I use this as an introductory example of introgression in my undergrad lectures - mainly because of the clear phenotypes and amazing courtship behaviour. It’s good to see someone has figured out the genetics…
I am stoked to read this paper. I worked as a field tech on this study system after undergrad. I got to go up the Rio Changuinola before it was dammed. It was an awesome experience.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Sequential introgression of a carotenoid processing gene underlies sexual ornament diversity in a genus of manakins
Integrative analyses reveal sequential instances of interspecies gene flow at a key gene controlling plumage coloration in birds.
www.science.org
December 3, 2024 at 1:48 PM
I use this as an introductory example of introgression in my undergrad lectures - mainly because of the clear phenotypes and amazing courtship behaviour. It’s good to see someone has figured out the genetics…
Reposted by Rick Fandino, PhD (He/Him/él)
People leaving Twitter for BlueSky like the elves in LOTR sailing west
a group of people in white robes are standing next to each other in a dark room .
Alt: Elves in Lord of the Rings preparing to leave Middle Earth for the Undying Lands
media.tenor.com
December 2, 2024 at 1:47 PM
People leaving Twitter for BlueSky like the elves in LOTR sailing west
Reposted by Rick Fandino, PhD (He/Him/él)
Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster. https://www.biorxiv.org/content/10.1101/2024.12.02.626067v1
Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster. https://www.biorxiv.org/content/10.1101/2024.12.02.626067v1
Chitin is a major component of arthropod extracellular matrices, including the exoskeleton and the m
www.biorxiv.org
December 2, 2024 at 4:32 PM
Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster. https://www.biorxiv.org/content/10.1101/2024.12.02.626067v1
Reposted by Rick Fandino, PhD (He/Him/él)
A great write up on the ivory lncRNA story written by Nick VanKuren and Marcus Kronforst. Congrats again to @lucalivraghi.bsky.social and @hwkmthcrspr.bsky.social for this amazing work!
www.pnas.org/doi/full/10....
www.pnas.org/doi/full/10....
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
December 2, 2024 at 8:55 PM
A great write up on the ivory lncRNA story written by Nick VanKuren and Marcus Kronforst. Congrats again to @lucalivraghi.bsky.social and @hwkmthcrspr.bsky.social for this amazing work!
www.pnas.org/doi/full/10....
www.pnas.org/doi/full/10....
Reposted by Rick Fandino, PhD (He/Him/él)
A lovely commentary on @lucalivraghi.bsky.social and @hwkmthcrspr.bsky.social's recent papers, by VanKuren and Kronforst (bsky-less?). "“Being wrong” has never been a bad thing in science because good scientists cannot let go of those little things that just do not line up" - 🔥🔥🔥
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
December 2, 2024 at 6:51 PM
A lovely commentary on @lucalivraghi.bsky.social and @hwkmthcrspr.bsky.social's recent papers, by VanKuren and Kronforst (bsky-less?). "“Being wrong” has never been a bad thing in science because good scientists cannot let go of those little things that just do not line up" - 🔥🔥🔥
Reposted by Rick Fandino, PhD (He/Him/él)
The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing https://www.biorxiv.org/content/10.1101/2024.11.18.623996v1
The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing https://www.biorxiv.org/content/10.1101/2024.11.18.623996v1
The epithelial sodium channel (ENaC) plays a key role in osmoregulation in tetrapod vertebrates and
www.biorxiv.org
November 20, 2024 at 1:35 AM
The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing https://www.biorxiv.org/content/10.1101/2024.11.18.623996v1
Reposted by Rick Fandino, PhD (He/Him/él)
Pure autofluorescence from the midband crystalline cones in a mantis shrimp eye. The fluorescence comes from mycosporine like amino acid pigments that absorb specific bands of UV light, thus tuning the UV sensitivity of the photoreceptors they focus light into. 🧪
#FluorescenceFriday
#FluorescenceFriday
November 15, 2024 at 2:18 PM
Pure autofluorescence from the midband crystalline cones in a mantis shrimp eye. The fluorescence comes from mycosporine like amino acid pigments that absorb specific bands of UV light, thus tuning the UV sensitivity of the photoreceptors they focus light into. 🧪
#FluorescenceFriday
#FluorescenceFriday
Reposted by Rick Fandino, PhD (He/Him/él)
We are here! Help us reconnect with any and all allies of the LGBTQ+ community in Plant Science!
November 14, 2024 at 2:32 AM
We are here! Help us reconnect with any and all allies of the LGBTQ+ community in Plant Science!
Reposted by Rick Fandino, PhD (He/Him/él)
Our study on the genetic architecture of a sexual mimicry polymorphism, led by graduate student Tris Dodge, is now out at Current Biology! www.sciencedirect.com/science/arti.... Original thread on the article is here:
bsky.app/profile/moll...
bsky.app/profile/moll...
Structural genomic variation and behavioral interactions underpin a balanced sexual mimicry polymorphism
How phenotypic diversity originates and persists within populations are classic puzzles in evolutionary biology. While balanced polymorphisms segregat…
www.sciencedirect.com
September 25, 2024 at 3:28 PM
Our study on the genetic architecture of a sexual mimicry polymorphism, led by graduate student Tris Dodge, is now out at Current Biology! www.sciencedirect.com/science/arti.... Original thread on the article is here:
bsky.app/profile/moll...
bsky.app/profile/moll...
Reposted by Rick Fandino, PhD (He/Him/él)
Local cryptic diversity in salinity adaptation mechanisms in a wild outcrossing Brassica https://www.biorxiv.org/content/10.1101/2024.04.18.590122v1
Local cryptic diversity in salinity adaptation mechanisms in a wild outcrossing Brassica https://www.biorxiv.org/content/10.1101/2024.04.18.590122v1
It is generally assumed that populations of the same species should evolve shared mechanisms of adap
www.biorxiv.org
April 22, 2024 at 9:32 PM
Local cryptic diversity in salinity adaptation mechanisms in a wild outcrossing Brassica https://www.biorxiv.org/content/10.1101/2024.04.18.590122v1
Reposted by Rick Fandino, PhD (He/Him/él)
Equity, Diversity and Inclusion: Unlocking the power of virtual networking for early-career researchers. #ECRs #EDI #DEI elifesciences.org/articles/963...
March 19, 2024 at 12:25 PM
Equity, Diversity and Inclusion: Unlocking the power of virtual networking for early-career researchers. #ECRs #EDI #DEI elifesciences.org/articles/963...
Reposted by Rick Fandino, PhD (He/Him/él)
Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut https://www.biorxiv.org/content/10.1101/2024.03.04.583343v1
Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut https://www.biorxiv.org/content/10.1101/2024.03.04.583343v1
The cloaca is a transient structure that forms in the terminal hindgut giving rise to the rectum dor
www.biorxiv.org
March 7, 2024 at 8:34 AM
Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut https://www.biorxiv.org/content/10.1101/2024.03.04.583343v1