Hugh Thomas
@hughthomas00.bsky.social
Deputy ed @lancetgastrohep - liver lover but fond of all things gastro. Former NatRevGastro. Commonly 🏃♂️ or 🚴. All nonsense entirely mine. Terminal convert from X.
I’m here in sunny Amsterdam on behalf of @lancetgastrohep.bsky.social for another stacked #EASLCongress 👋
Email or DM or just say hi to chat about submissions 🙌
Email or DM or just say hi to chat about submissions 🙌
May 8, 2025 at 9:22 AM
I’m here in sunny Amsterdam on behalf of @lancetgastrohep.bsky.social for another stacked #EASLCongress 👋
Email or DM or just say hi to chat about submissions 🙌
Email or DM or just say hi to chat about submissions 🙌
From H pylori prevalence to diet and #IBS, via #HCC screening and viral #hepatitis, this is LancetGastro2024, as visualised by @mempathie.bsky.social
Thank you authors, reviewers, advisory board members, and all at @thelancet.bsky.social involved in getting an issue published each month!
Thank you authors, reviewers, advisory board members, and all at @thelancet.bsky.social involved in getting an issue published each month!
December 20, 2024 at 1:43 PM
From H pylori prevalence to diet and #IBS, via #HCC screening and viral #hepatitis, this is LancetGastro2024, as visualised by @mempathie.bsky.social
Thank you authors, reviewers, advisory board members, and all at @thelancet.bsky.social involved in getting an issue published each month!
Thank you authors, reviewers, advisory board members, and all at @thelancet.bsky.social involved in getting an issue published each month!
The Adam Curtis doco you really didn't know you needed
THREAD
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
December 20, 2024 at 10:58 AM
The Adam Curtis doco you really didn't know you needed
Good article in Nature on the INSPECT-SR project I had the pleasure of contributing to (preprint now at doi.org/10.1101/2024...)
Most problematic trials probably have little clinical impact on their own. But sys-revs that inadvertently include them risk 'laundering' their findings to wide audience!
Most problematic trials probably have little clinical impact on their own. But sys-revs that inadvertently include them risk 'laundering' their findings to wide audience!
Fake or flawed studies are polluting systematic reviews in medicine and other fields - but how do you spot them?
For Nature, I report on efforts to create a short checklist of red flags, and on the automated integrity tools emerging to help.
www.nature.com/articles/d41...
For Nature, I report on efforts to create a short checklist of red flags, and on the automated integrity tools emerging to help.
www.nature.com/articles/d41...
Giant study finds untrustworthy trials pollute gold-standard medical reviews
Two-year collaboration aims to create tools to help counter the tide of flawed research.
www.nature.com
December 18, 2024 at 6:26 PM
Good article in Nature on the INSPECT-SR project I had the pleasure of contributing to (preprint now at doi.org/10.1101/2024...)
Most problematic trials probably have little clinical impact on their own. But sys-revs that inadvertently include them risk 'laundering' their findings to wide audience!
Most problematic trials probably have little clinical impact on their own. But sys-revs that inadvertently include them risk 'laundering' their findings to wide audience!
Ouch. Only 16 MDPI and 22 Frontiers journals to remain at level 1 (includes Frontiers in Gastro)
Big news from Finnish publication forum. Almost all MDPI and Frontiers journals will be downgraded to level 0 and thus are not considered as properly peer reviewed trustworthy scientific journals.
julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi/en/news/chan...
Changes to the classification
julkaisufoorumi.fi
December 17, 2024 at 11:04 AM
Ouch. Only 16 MDPI and 22 Frontiers journals to remain at level 1 (includes Frontiers in Gastro)
Reposted by Hugh Thomas
A well balanced editorial from the team at the Lancet Gastroenterology & Hepatology this month on the contentious topic of UPFs.
💯 in agreement:
"Pleas to overhaul the food system to mitigate the specific harms of UPFs are well meaning but overly reliant on limited data...
💯 in agreement:
"Pleas to overhaul the food system to mitigate the specific harms of UPFs are well meaning but overly reliant on limited data...
December 13, 2024 at 12:01 PM
A well balanced editorial from the team at the Lancet Gastroenterology & Hepatology this month on the contentious topic of UPFs.
💯 in agreement:
"Pleas to overhaul the food system to mitigate the specific harms of UPFs are well meaning but overly reliant on limited data...
💯 in agreement:
"Pleas to overhaul the food system to mitigate the specific harms of UPFs are well meaning but overly reliant on limited data...
Reposted by Hugh Thomas
Amazing to watch commentators and outlets attribute these findings to UPFs and seed oils when the study doesn't even look at this. The assumption that eating more linoleic acid -> higher tissue arachidonic acid enrichment has fueled so many handwavey hypotheses despite metabolic regulation
December 14, 2024 at 3:08 AM
Amazing to watch commentators and outlets attribute these findings to UPFs and seed oils when the study doesn't even look at this. The assumption that eating more linoleic acid -> higher tissue arachidonic acid enrichment has fueled so many handwavey hypotheses despite metabolic regulation
Think this article yields too many qs about underlying observational work to be v useful
Eg, is this an attempt to isolate specific UPF effects (if so, do they relate to all UPF products)? Or do effects reflect overall nutritional content of diets (if so, invocation of UPF nomenclature misleading)?
Eg, is this an attempt to isolate specific UPF effects (if so, do they relate to all UPF products)? Or do effects reflect overall nutritional content of diets (if so, invocation of UPF nomenclature misleading)?
NEW:
Ultra-processed foods may cause muscle fattening even if calorie consumption isn't excessive, study finds. @financialtimes.com
Research intensifies debate over health risks of mass-produced goods made more palatable for consumers
www.ft.com/content/cf5a...
Ultra-processed foods may cause muscle fattening even if calorie consumption isn't excessive, study finds. @financialtimes.com
Research intensifies debate over health risks of mass-produced goods made more palatable for consumers
www.ft.com/content/cf5a...
Ultra-processed foods fatten muscles even if not eaten in large amounts, study finds
Research intensifies debate over health risks of mass-produced goods made more palatable for consumers
www.ft.com
December 4, 2024 at 4:14 PM
Think this article yields too many qs about underlying observational work to be v useful
Eg, is this an attempt to isolate specific UPF effects (if so, do they relate to all UPF products)? Or do effects reflect overall nutritional content of diets (if so, invocation of UPF nomenclature misleading)?
Eg, is this an attempt to isolate specific UPF effects (if so, do they relate to all UPF products)? Or do effects reflect overall nutritional content of diets (if so, invocation of UPF nomenclature misleading)?
As if it needed illustrating that Bluesky is the new domain for sharing and discussing scientific content ⬇
December 4, 2024 at 9:23 AM
As if it needed illustrating that Bluesky is the new domain for sharing and discussing scientific content ⬇
The original article will live long in the memory, featuring earnest claims of brain-resident chloroplasts
December 3, 2024 at 1:15 PM
The original article will live long in the memory, featuring earnest claims of brain-resident chloroplasts
Now on Bluesky 👇
The cost of inaction in early childhood is high.
In our latest issue, a Lancet Series calls for wider investment to ensure children in 'the next 1000 days' have access to adequate nurturing care.
Find this & more 👉 bit.ly/3CKjIvH
In our latest issue, a Lancet Series calls for wider investment to ensure children in 'the next 1000 days' have access to adequate nurturing care.
Find this & more 👉 bit.ly/3CKjIvH
![Cover of The Lancet's Nov 23, 2024 issue. Quote on cover reads: "The next 1000 days [from 2-5 years of age] are a key period for children's development, and providing adequate support for children in this period is of crucial importance for their long-term development."](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ypu6bwefbbzhcvojdj7mz657/bafkreifa63iwzrb6dvfm4c3vz6u5hkkulbt6u37o7ckojer4jnoamkl7xe@jpeg)
November 27, 2024 at 10:12 PM
Now on Bluesky 👇
Reposted by Hugh Thomas
For those of you who keep asking;
No we don't capture attention from clinical guidelines by "walking around hospitals listening for DOIs and writing them all down."
No we don't capture attention from clinical guidelines by "walking around hospitals listening for DOIs and writing them all down."
November 27, 2024 at 2:33 PM
For those of you who keep asking;
No we don't capture attention from clinical guidelines by "walking around hospitals listening for DOIs and writing them all down."
No we don't capture attention from clinical guidelines by "walking around hospitals listening for DOIs and writing them all down."
Interim data (n=18/36) from new @kevinh-phd.bsky.social crossover trial
clinicaltrials.gov/study/NCT052...
⬆ 1-week energy consumption w/ #UPF diets high in energy density/palatability (UPF hh) & high energy dense/low palatability (UPF hl) vs MPF & UPF diet low in energy density/palatability
clinicaltrials.gov/study/NCT052...
⬆ 1-week energy consumption w/ #UPF diets high in energy density/palatability (UPF hh) & high energy dense/low palatability (UPF hl) vs MPF & UPF diet low in energy density/palatability
November 26, 2024 at 11:00 AM
Interim data (n=18/36) from new @kevinh-phd.bsky.social crossover trial
clinicaltrials.gov/study/NCT052...
⬆ 1-week energy consumption w/ #UPF diets high in energy density/palatability (UPF hh) & high energy dense/low palatability (UPF hl) vs MPF & UPF diet low in energy density/palatability
clinicaltrials.gov/study/NCT052...
⬆ 1-week energy consumption w/ #UPF diets high in energy density/palatability (UPF hh) & high energy dense/low palatability (UPF hl) vs MPF & UPF diet low in energy density/palatability
Tuning into #IBResearch #UltraProcessedFood conference today. The day kicks off with the same tired COI attacks. Deeply dispiriting.
November 26, 2024 at 10:26 AM
Tuning into #IBResearch #UltraProcessedFood conference today. The day kicks off with the same tired COI attacks. Deeply dispiriting.
Anyone who has followed this story won't be surprised to hear that simufilam missed both phase 3 co-primary endpoints. A bleak tale of fraud and threats finally brought to a close, years too late. www.cassavasciences.com/news-release...
www.science.org/content/arti...
www.science.org/content/arti...
www.cassavasciences.com
November 25, 2024 at 3:05 PM
Anyone who has followed this story won't be surprised to hear that simufilam missed both phase 3 co-primary endpoints. A bleak tale of fraud and threats finally brought to a close, years too late. www.cassavasciences.com/news-release...
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Hugh Thomas
New at The Lancet Child & Adolescent Health — Paediatric acute liver failure: a multidisciplinary perspective on when a critically ill child is unsuitable for liver transplantation
www.thelancet.com/journals/lan...
#LiverSky
www.thelancet.com/journals/lan...
#LiverSky
Paediatric acute liver failure: a multidisciplinary perspective on when a critically ill child is unsuitable for liver transplantation
Paediatric acute liver failure is a devastating condition with high morbidity and
mortality, which is challenging to manage for the hepatologist, intensivist, and associated
specialists. Emergency liv...
www.thelancet.com
November 20, 2024 at 1:30 PM
New at The Lancet Child & Adolescent Health — Paediatric acute liver failure: a multidisciplinary perspective on when a critically ill child is unsuitable for liver transplantation
www.thelancet.com/journals/lan...
#LiverSky
www.thelancet.com/journals/lan...
#LiverSky
@altmetric.com have rolled out data for article citations in clinical guidelines, giving new insight into clinical impact for publications, and I couldn't resist having a dig into it for #LancetGastroHep
November 20, 2024 at 10:31 AM
@altmetric.com have rolled out data for article citations in clinical guidelines, giving new insight into clinical impact for publications, and I couldn't resist having a dig into it for #LancetGastroHep
Reposted by Hugh Thomas
We are on our second starter pack for GI / Hepatology
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
November 15, 2024 at 3:17 PM
We are on our second starter pack for GI / Hepatology
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
@altmetric.com have been doing some killer updates recently, and more to come 👀
November 16, 2024 at 7:51 AM
@altmetric.com have been doing some killer updates recently, and more to come 👀
Won’t take long!
November 15, 2024 at 6:19 PM
Won’t take long!
#TLM24 late-breakers out now, feat ESSENCE phase 3 of #semaglutide in #MASH
www.aasld.org/sites/defaul...
www.aasld.org/sites/defaul...
November 15, 2024 at 4:20 PM
#TLM24 late-breakers out now, feat ESSENCE phase 3 of #semaglutide in #MASH
www.aasld.org/sites/defaul...
www.aasld.org/sites/defaul...
Reposted by Hugh Thomas
New starter pack! First attempt at curating a community of amazing #womeninmedicine
Who else should I add? #MedSky
Who else should I add? #MedSky
November 11, 2024 at 12:41 AM
New starter pack! First attempt at curating a community of amazing #womeninmedicine
Who else should I add? #MedSky
Who else should I add? #MedSky
Refreshing here, isn’t it? In related news, happy to share a new (free) Comment capturing some thoughts from our internal work on misinformation. Health is a unifying force, and we cannot allow misinformation and disinformation - from any source - to distort that.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
To keep health as a unifying force, we must put resources into tackling health misinformation and disinformation
Health is political. This is what many practitioners of public and clinical health
believe. Health and health policy are shaped by the political ideology of governments,
whether that means more money ...
www.thelancet.com
November 14, 2024 at 11:02 PM
Refreshing here, isn’t it? In related news, happy to share a new (free) Comment capturing some thoughts from our internal work on misinformation. Health is a unifying force, and we cannot allow misinformation and disinformation - from any source - to distort that.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...