Hocine Rekaik
@hocinerekaik.bsky.social
Postdoc at @Duboule lab. Biologist interested in mechanisms of gene regulation and chromatin 3D architecture
Reposted by Hocine Rekaik
First retreat of our #DynaTrans @erc.europa.eu synergy consortium. Great science and interactions, (little) wine testing and (lots of-) Poisson distributions with the Gregor @pasteur.fr, Tkacik #ISTA and our @college-de-france.fr labs, in wonderful #Ermenonville castle🤘
November 25, 2025 at 2:59 PM
First retreat of our #DynaTrans @erc.europa.eu synergy consortium. Great science and interactions, (little) wine testing and (lots of-) Poisson distributions with the Gregor @pasteur.fr, Tkacik #ISTA and our @college-de-france.fr labs, in wonderful #Ermenonville castle🤘
Reposted by Hocine Rekaik
Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social.
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
Cadherins modulate the self-organizing potential of pseudo-embryos
Gastruloids derived from ES cells mimic embryonic patterning through robust self-organization.
Mayran et al. uncover that this competence depends on a cadherin switch regulated
by Snai1-driven E-cadhe...
www.cell.com
November 17, 2025 at 10:37 AM
Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social.
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
Reposted by Hocine Rekaik
Out today. 🙏 again to everyone for this wonderful piece of work, in particular to Aurelie @aurhin.bsky.social Chase @chasebolt.bsky.social and Brent @homeobox.bsky.social. 🙏 also to the Harris lab @fish4walking.bsky.social and @neilshubin.bsky.social @biology-unige.bsky.social @college-de-france.fr
September 17, 2025 at 5:30 PM
Out today. 🙏 again to everyone for this wonderful piece of work, in particular to Aurelie @aurhin.bsky.social Chase @chasebolt.bsky.social and Brent @homeobox.bsky.social. 🙏 also to the Harris lab @fish4walking.bsky.social and @neilshubin.bsky.social @biology-unige.bsky.social @college-de-france.fr
Reposted by Hocine Rekaik
⏳ Still time to register + submit your poster abstract
🗓️ Deadline: Sept 19!
🗓️ Deadline: Sept 19!
Registration is now open!
Gastrulation Reloaded: Developing, engineering & evolving the body plan
📅 October 14–17, 2025
📍 Paris, France
🗓️ Abstract & early bird deadline: July 15, 2025
www.gastrulation-reloaded.conferences-pasteur.org/home
Exceptional lineup of speakers & many selected talks
Gastrulation Reloaded: Developing, engineering & evolving the body plan
📅 October 14–17, 2025
📍 Paris, France
🗓️ Abstract & early bird deadline: July 15, 2025
www.gastrulation-reloaded.conferences-pasteur.org/home
Exceptional lineup of speakers & many selected talks
September 5, 2025 at 2:48 PM
⏳ Still time to register + submit your poster abstract
🗓️ Deadline: Sept 19!
🗓️ Deadline: Sept 19!
Reposted by Hocine Rekaik
Our work bridging enhancer-promoter proximity to phenotypic outcomes in vivo is out! Shout out to @olimpiabompadre.bsky.social, to Marie Kmita's lab, and to all the co-authors. www.nature.com/articles/s41...
Liebenberg syndrome severity arises from variations in Pitx1 locus topology and proportion of ectopically transcribing cells - Nature Communications
Here the authors show that reducing enhancer-promoter distance at the Pitx1 locus increases proportion of Pitx1 forelimb expressing cells, worsening skeletal defects in Liebenberg syndrome. They also ...
www.nature.com
July 9, 2025 at 11:58 AM
Our work bridging enhancer-promoter proximity to phenotypic outcomes in vivo is out! Shout out to @olimpiabompadre.bsky.social, to Marie Kmita's lab, and to all the co-authors. www.nature.com/articles/s41...
Reposted by Hocine Rekaik
Just in a week from now! Open symposium @collegedefrance.bsky.social in Paris 😎. The state of the art on enhancer sequences. Import tax-free (for everyone).
April 3, 2025 at 9:53 AM
Just in a week from now! Open symposium @collegedefrance.bsky.social in Paris 😎. The state of the art on enhancer sequences. Import tax-free (for everyone).
Reposted by Hocine Rekaik
Symposium on ‘Enhancer Sequences’ at beautiful @collegedefrance.bsky.social in Paris, by April 11th. Open and free, no registration. Come to relax listening to facts #TherapeuticEffects #VillageGauloix Final programme below. Tell your friends! 🙏🤘
March 17, 2025 at 2:28 PM
Symposium on ‘Enhancer Sequences’ at beautiful @collegedefrance.bsky.social in Paris, by April 11th. Open and free, no registration. Come to relax listening to facts #TherapeuticEffects #VillageGauloix Final programme below. Tell your friends! 🙏🤘
🙏
Somites get lost without Hox keeping time ⌚
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
3rd Crick Beddington Symposium: Somites get lost without Hox keeping time - the Node
The 3rd Crick-Beddington Symposium, in memory of Rosa Beddington FRS (1956-2001), took place on 10th-11th February at the Francis Crick Institute, London.
thenode.biologists.com
March 12, 2025 at 7:41 PM
🙏
Reposted by Hocine Rekaik
Somites get lost without Hox keeping time ⌚
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
3rd Crick Beddington Symposium: Somites get lost without Hox keeping time - the Node
The 3rd Crick-Beddington Symposium, in memory of Rosa Beddington FRS (1956-2001), took place on 10th-11th February at the Francis Crick Institute, London.
thenode.biologists.com
March 12, 2025 at 4:44 PM
Somites get lost without Hox keeping time ⌚
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
One of #theNodeCorrespondents Alex Neaverson recently attended the 3rd Crick Beddington Symposium, and spoke to Hocine Rekaik @hocinerekaik.bsky.social about his poster:
thenode.biologists.com/3rd-crick-be...
Reposted by Hocine Rekaik
Cette année, mon cours @collegedefrance.bsky.social traitera de la régulation des gènes par les séquences enhancers. Une des clés de notre développement. Premier cours le vendredi 21 février à 10h. Entrée libre, salle chauffée. Amis et Collègues parisiens, merci de diffuser!
February 4, 2025 at 9:33 AM
Cette année, mon cours @collegedefrance.bsky.social traitera de la régulation des gènes par les séquences enhancers. Une des clés de notre développement. Premier cours le vendredi 21 février à 10h. Entrée libre, salle chauffée. Amis et Collègues parisiens, merci de diffuser!
Reposted by Hocine Rekaik
We seek a bioinformatician to join our group at the College de France, Paris. If you like genomics, 3D genome organization, gene regulation, and development check out the offer and get in touch!
January 31, 2025 at 11:09 AM
We seek a bioinformatician to join our group at the College de France, Paris. If you like genomics, 3D genome organization, gene regulation, and development check out the offer and get in touch!
Reposted by Hocine Rekaik
For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here www.biorxiv.org/content/10.1...
@Dias and colleagues uncover the reason and explain the implications for our understanding of mammalian gastrulation
🧵
@Dias and colleagues uncover the reason and explain the implications for our understanding of mammalian gastrulation
🧵
January 12, 2025 at 11:09 AM
For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here www.biorxiv.org/content/10.1...
@Dias and colleagues uncover the reason and explain the implications for our understanding of mammalian gastrulation
🧵
@Dias and colleagues uncover the reason and explain the implications for our understanding of mammalian gastrulation
🧵
Reposted by Hocine Rekaik
Why adults should be on top of the hourglass and embryos at the bottom, rather than the opposite. And why a mountain rope with carabiners cannot fully explain the dynamics of gene extrusion by loop extrusion. Special issue on the #organizer #InHoxWeTrust
doi.org/10.1016/j.cdev.2024.203991
doi.org/10.1016/j.cdev.2024.203991
January 6, 2025 at 8:34 AM
Why adults should be on top of the hourglass and embryos at the bottom, rather than the opposite. And why a mountain rope with carabiners cannot fully explain the dynamics of gene extrusion by loop extrusion. Special issue on the #organizer #InHoxWeTrust
doi.org/10.1016/j.cdev.2024.203991
doi.org/10.1016/j.cdev.2024.203991
Reposted by Hocine Rekaik
🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders?
Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing
🔗 www.biorxiv.org/content/10.1...
Happy New Year, everyone! 🎉
🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing
🔗 www.biorxiv.org/content/10.1...
Happy New Year, everyone! 🎉
🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
January 6, 2025 at 8:37 AM
🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders?
Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing
🔗 www.biorxiv.org/content/10.1...
Happy New Year, everyone! 🎉
🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing
🔗 www.biorxiv.org/content/10.1...
Happy New Year, everyone! 🎉
🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
Reposted by Hocine Rekaik
This Primer completes the "40 years of the homeobox" subject collection. You can check out the full collection of review-type articles published throughout 2024:
https://journals.biologists.com/dev/collection/10249/40-years-of-the-homeobox
#DevBio
https://journals.biologists.com/dev/collection/10249/40-years-of-the-homeobox
#DevBio
December 18, 2024 at 9:51 AM
This Primer completes the "40 years of the homeobox" subject collection. You can check out the full collection of review-type articles published throughout 2024:
https://journals.biologists.com/dev/collection/10249/40-years-of-the-homeobox
#DevBio
https://journals.biologists.com/dev/collection/10249/40-years-of-the-homeobox
#DevBio