Harry Fu
@harryfulab.bsky.social
@Harry Fu Lab, Assistant Professor at The Ohio State University Wexner Medical Center. My lab studies the pathogenesis of Alzheimer’s disease, Frontotemporal dementia, and Traumatic brain injury.
Reposted by Harry Fu
Human microglia differentially respond to β-amyloid, tau, and combined Alzheimer's disease pathologies in vivo
alz-journals.onlinelibrary.wiley.com/doi/10.1002/... @alzdemjournals.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/... @alzdemjournals.bsky.social
November 21, 2025 at 2:24 PM
Human microglia differentially respond to β-amyloid, tau, and combined Alzheimer's disease pathologies in vivo
alz-journals.onlinelibrary.wiley.com/doi/10.1002/... @alzdemjournals.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/... @alzdemjournals.bsky.social
Thank you #AAIC2025 for your great support for our talented young scientists who are interested in Alzheimer’s disease. Congratulations on all Poster competition winners, including my fantastic PhD student, Tae Yeon Kim. So proud of you!!!
July 31, 2025 at 10:42 PM
Thank you #AAIC2025 for your great support for our talented young scientists who are interested in Alzheimer’s disease. Congratulations on all Poster competition winners, including my fantastic PhD student, Tae Yeon Kim. So proud of you!!!
Reposted by Harry Fu
Human neural organoids suggest the protein GRAMD1B may influence cholesterol and lipid management in neurons, potentially impacting treatments for neurodegenerative diseases like FTLD and Alzheimer's. doi.org/g9dwst
Human 'mini-brains' reveal protein GRAMD1B's potential role in neurodegeneration
Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids—also known as "mini-brain" models—from patients with frontotemporal lobar degeneration (FTLD).
medicalxpress.com
April 9, 2025 at 9:02 AM
Human neural organoids suggest the protein GRAMD1B may influence cholesterol and lipid management in neurons, potentially impacting treatments for neurodegenerative diseases like FTLD and Alzheimer's. doi.org/g9dwst
Reposted by Harry Fu
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
www.nature.com/articles/s41...
www.nature.com/articles/s41...
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau - Nature Communications
The relationship between lipid dyshomeostasis and tau pathology in FTLD and AD remains unclear. Here, the authors demonstrate that GRAMD1B contributes to lipid dyshomeostasis, autophagy impairment, an...
www.nature.com
April 9, 2025 at 3:11 PM
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Harry Fu
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau www.nature.com/articles/s41...
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau - Nature Communications
The relationship between lipid dyshomeostasis and tau pathology in FTLD and AD remains unclear. Here, the authors demonstrate that GRAMD1B contributes to lipid dyshomeostasis, autophagy impairment, an...
www.nature.com
April 9, 2025 at 12:16 PM
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau www.nature.com/articles/s41...
Happy holidays from the Fu lab! Wish you and your loved ones have a wonderful holiday season!
December 24, 2024 at 2:42 AM
Happy holidays from the Fu lab! Wish you and your loved ones have a wonderful holiday season!
Reposted by Harry Fu
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Implementation and validation of single-cell genomics experiments in neuroscience - Nature Neuroscience
Single-cell or single-nucleus RNA-sequencing experiments form a basis for biological insights about cell types and states, but they require orthogonal experiments to confirm the functional relevance o...
www.nature.com
December 6, 2024 at 6:38 PM
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...