Ester Hammond
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hammond-lab.bsky.social
Ester Hammond
@hammond-lab.bsky.social
Cancer biology Prof at Oxford University, focused on the biological response to hypoxia including replication stress, UPR and transcription
Reposted by Ester Hammond
Interested in inherited chromosomal instability syndromes and DNA repair? We are looking for an enthusiastic person to join the Stewart lab at the University of Birmingham as a senior technician. Please checkout the job advert: www.jobs.ac.uk/job/DPH515/senior-research-technician
Senior Research Technician at University of Birmingham
An academic position as a Senior Research Technician is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.
www.jobs.ac.uk
November 6, 2025 at 8:34 AM
Funded PhD available working with us on tumour hypoxia and radiosensitivity at @oncology.ox.ac.uk @ox.ac.uk Closing date 2nd Dec www.oncology.ox.ac.uk/study-with-u...
Oxford Wolfson Marriott Graduate Scholarship: Investigating changes in RNA-binding proteins in hypoxia as a means of increasing radiosensitivity
www.oncology.ox.ac.uk
November 5, 2025 at 4:19 PM
Reposted by Ester Hammond
November 5, 2025 at 9:18 AM
Reposted by Ester Hammond
New CRUK Post-doc position in our group. #mutationalorder #multiomics #cancer.
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
October 6, 2025 at 10:55 AM
Reposted by Ester Hammond
Hypoxia-activated PROTACs (HAP-TACs) are online in @jacs.acspublications.org (pubs.acs.org/doi/10.1021/...)! Collborative work with Ester Hammond (@hammond-lab.bsky.social). Congrats to Marta Serafini, Sophie Twigger, George Delfas, Max Mallerman, Elliot Bailey & Ewen Calder (@ecalder.bsky.social).
Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells
Proteolysis targeting chimeras (PROTACs) have helped to establish proximity induction as an exciting strategy in drug discovery, and there are multiple clinical trials focused on this modality. Howeve...
pubs.acs.org
September 25, 2025 at 3:47 PM
Great end to the week! Thank you to @sophietwigger.bsky.social for aiming high and getting us the Gold award. @oncology.ox.ac.uk
July 25, 2025 at 3:34 PM
Reposted by Ester Hammond
Join us for our DPhil in Cancer Science Open Day on Tuesday 2nd September at 12:30pm to find out how a DPhil can be the next step in your cancer research career development!

Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk

www.eventbrite.co.uk/e/university...
University of Oxford - DPhil in Cancer Science Open Day
Join the Virtual DPhil in Cancer Science Open Day to hear more about Oxford’s world-leading research training
www.eventbrite.co.uk
July 18, 2025 at 3:16 PM
Reposted by Ester Hammond
Our pre-print on the development of bivalent ligands for the TRIM24 bromodomain & PHD is now online chemrxiv.org/engage/chemr...

Congratulations to the authors: Michael Platt, Ekaterina Kot, Louise Martin, Antoine Wallabrègue, Liwen Song, Alistair Boyd, Lizbé Koekemoer, & @hammond-lab.bsky.social
July 2, 2025 at 7:20 PM
Reposted by Ester Hammond
As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.

This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
June 21, 2025 at 3:32 PM
Reposted by Ester Hammond
Our pre-print on hypoxia-activated PROTACs (HAP-TACs) is now on ChemRvix: chemrxiv.org/engage/chemr...

We used the indolequinone bioreductive group to protect VHL- or CRBN-recruiting BRD4 degraders rendering them inactive. This group is removed selectively in hypoxia, revealing the active PROTAC.
June 21, 2025 at 3:32 PM
Reposted by Ester Hammond
Exciting news!!! We are recruiting a RA to join my lab at
‪@oncology.ox.ac.uk‬ to study epigenetic reprogramming in stem cells and within the TME using colon organoids

www.oncology.ox.ac.uk/team/giulia-...

Deadline 2nd of July (my.corehr.com/pls/uoxrecru...)

Re-post are very welcome!
my.corehr.com
June 13, 2025 at 9:37 AM
Reposted by Ester Hammond
We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms.

Please get in touch with your CV if you are interested; closing date: 27th June 2025.

More details here: candidate.hr-manager.net/ApplicationI...
Postdoctoral Research Associate in the Blackford Group
A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th
candidate.hr-manager.net
May 29, 2025 at 11:26 AM
We really are fans of cross-disciplinary projects! Delighted to have contributed to some #PlantScience
May 12, 2025 at 4:34 PM
I highly recommend working with @kleszczynsk.bsky.social If you're looking for a postdoc and interested in hypoxia and epigenetics take a look at nencki.edu.pl/job/the-nenc...
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN Accessibility toolsIncrease TextDecrease TextGrayscaleHigh contrastReset
nencki.edu.pl
May 7, 2025 at 8:26 AM
Reposted by Ester Hammond
Meet @halaestephan.bsky.social 👩‍🔬🔬🧪

Hala is a postdoctoral researcher here at the oncology department, working on cancer immunology.

To mark #IWD25, Hala shares her STEM journey & her advice on how to thrive as a woman in academia.

@medsci.ox.ac.uk @hammond-lab.bsky.social
#InternationalWomensDay
March 10, 2025 at 3:15 PM
Great opportunity for anyone looking for a post doc in Oxford - highly recommend!
🚨Our post is now live! Apply and join us!

my.corehr.com/pls/uoxrecru...
🚨Thanks to generous support from @cancerresearchuk.org, we have multiple postdoctoral positions available in our lab (www.mardakhehlab.info) @oxfordbiochemistry.bsky.social to study ribosomes synthesis in cancer. Get in touch if you’re interested + RT and spread the word! 📣 #cancer #RNA 🚨
March 6, 2025 at 7:00 AM
Reposted by Ester Hammond
Great to see this collaborative work with @emilyflashman.bsky.social and @hammond-lab.bsky.social on @biorxivpreprint.bsky.social. Using our previously developed hypoxia probes (pubs.acs.org/doi/full/10....) to image hypoxia in plants.
February 27, 2025 at 11:25 PM
Reposted by Ester Hammond
Curious about doing a PhD? 🤔

Join Oxford's research community and work with academic staff on projects in a range of subject areas.

UNIQ+ research internships are now open for applications from UK undergraduates from under-represented and disadvantaged backgrounds.

More info ⬇️
What is a UNIQ+ Research Internship? | University of Oxford
What is UNIQ+?UNIQ+ Research Internships are designed to provide students from under-represented and disadvantaged backgrounds who are ordinarily resident in the UK with the opportunity to experience
www.ox.ac.uk
February 7, 2025 at 10:12 AM
Reposted by Ester Hammond
The MSc in Medical Physics with Radiobiology at @oncology.ox.ac.uk welcomes students looking to kickstart a career in medical physics research, clinical practice, or industry.

Find out more: tinyurl.com/4a4km74v
January 22, 2025 at 2:55 PM
Reposted by Ester Hammond
ICYMI

We are recruiting a new Associate Professor in cell and molecular biology, with a preference for immunology, inflammation and/or infection - all defined broadly

Come and be our colleague!

Deadline 28 Feb, please spread the word!

www.path.ox.ac.uk/vacancy/asso...
January 22, 2025 at 3:09 PM
Congratulations to the new Dr Twigger @sophietwigger.bsky.social and many thanks to Angie Russell and Navita Somaiah for examining. Let the celebrations commence
January 7, 2025 at 4:09 PM
Great start to 2025. Tumor hypoxia promotes immune evasion by autophagy-mediated downregulation of MHC class I expression leading to reduced antigen presentation. Great work from @halaestephan.bsky.social www.embopress.org/doi/full/10....
Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation | The EMBO Journal
imageimageHypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor hypoxia promotes immune evasion by autophagy-mediated downregulation ...
www.embopress.org
January 3, 2025 at 9:30 AM
Reposted by Ester Hammond
Are you full of ideas, thinking about applying for fellowships and looking for a home i.e. junior group leader position? We're recruiting! my.corehr.com/pls/uoxrecru...
Job Details
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December 30, 2024 at 3:51 PM
We enjoyed a great holiday celebration, throwing some darts (some better than others) and eating lots. Happy holidays to all @sophietwigger.bsky.social @katroseworth.bsky.social @olivierzanier.bsky.social @brightw.bsky.social @halaestephan.bsky.social @edpetrosyan.bsky.social @chuminz.bsky.social
December 16, 2024 at 8:44 PM
Exciting opportunity to establish your own research group in the Department of Oncology at Oxford. Please spread the word

my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
December 10, 2024 at 8:22 AM