Ester Hammond
@hammond-lab.bsky.social
Cancer biology Prof at Oxford University, focused on the biological response to hypoxia including replication stress, UPR and transcription
Reposted by Ester Hammond
As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
June 21, 2025 at 3:32 PM
As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.