HaGe Sprenger
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hagesprenger.bsky.social
HaGe Sprenger
@hagesprenger.bsky.social
Metabolism & Mitochondria
https://www.age.mpg.de/sprenger
Reposted by HaGe Sprenger
Atlas of Lysosomal Aging Reveals a Molecular Clock of Storage Disorder-Associated Metabolites https://www.biorxiv.org/content/10.1101/2025.09.25.678303v1
September 26, 2025 at 5:30 PM
Reposted by HaGe Sprenger
We are hiring 🔍📢

Are you curious about how exercise promotes positive changes at the molecular level in obesity and diabetes? Then apply as a Postdoctoral Researcher in Dr. Melanie Mittenbühlers team.

Read more: ddz.de/job/postdoct...

@mellimittenblr.bsky.social
August 8, 2025 at 10:03 AM
Reposted by HaGe Sprenger
🚀 What’s it like to launch a new lab? Hans-Georg Sprenger shares challenges, early wins & the joy of mentoring in molecular metabolism research. @mpiage.bsky.social
Read the interview: febs.onlinelibrary.wiley.com/doi/10.1002/...
#ScienceCareers #Mentoring #ResearchLife
August 8, 2025 at 12:43 PM
Reposted by HaGe Sprenger
‼️ We're looking for a postdoc to join our team starting January 1st, 2026! ‼️
Are you curious about how exercise promotes positive changes at the molecular level in obesity and diabetes? If so, consider applying or reach out with any questions.

ddz.de/job/postdoct...

ddz.de/en/research/...
Postdoctoral Researcher (Ph.D./Dr. rer. nat., m/f/div., E13 TV-L, 100%) - Deutsches Diabetes-Zentrum (DDZ)
Institut für Klinische Biochemie und Pathobiochemie (Direktor: Univ.-Prof. Dr. rer. nat. Hadi Al-Hasani), Nachwuchsforschungsgruppe Crosstalk (Leiterin: Melanie Mittenbühler, Dr.) (25019)
ddz.de
July 30, 2025 at 10:53 AM
Our paper showing that ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST is now published @cp-cellmetabolism.bsky.social

Thanks to everyone involved!

www.cell.com/cell-metabol...
February 17, 2025 at 5:33 PM
Reposted by HaGe Sprenger
Very happy to share that my research group has launched at the German Diabetes Center (DDZ) in Düsseldorf!

We're looking for a PhD student to study the effects of inter-tissue communication on energy balance and metabolic health. Interested? Get in touch!

ddz.de/en/job/docto...
Doctoral Student (PhD/Dr. rer. nat., m/f/div., E13 TV-L 65%) - Deutsches Diabetes-Zentrum (DDZ)
A job-opening of the German Diabetes-Center (DDZ). (24681)
ddz.de
February 13, 2025 at 9:11 AM
Reposted by HaGe Sprenger
Hi all, our lab will soon recruit a PhD student working within a very exciting MSCA Horizon Doctoral network working on ageing, UNION, which gathers some fantastic scientists. Please apply if your profile fits our project (see attached advert).
Looking forward to working with you!
January 23, 2025 at 8:37 AM
Reposted by HaGe Sprenger
New article by @platorremuro.bsky.social published in @naturecellbiology.bsky.social Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity- With Kajimura, Gygi and Eck labs @danafarber.bsky.social @harvardcellbio.bsky.social
rdcu.be/d5ptF
January 3, 2025 at 11:14 AM
Reposted by HaGe Sprenger
Thrilled to share our new paper @Chouchani Lab in Cell; what a great way to end this year! We establish a deep mapping of the zinc-binding human cysteine proteome (ZnCPT) and discover glutathione reductase as zinc-targetable cancer vulnerability. www.cell.com/cell/fulltex...
The human zinc-binding cysteine proteome
A deep mapping of the human zinc-binding cysteine proteome (ZnCPT) defines thousands of zinc-binding protein cysteines across major domains of biology and discovers glutathione reductase as zinc-targetable cancer vulnerability.
www.cell.com
December 31, 2024 at 4:21 PM
Reposted by HaGe Sprenger
I'm thrilled to co-organize the inaugural #AdiposeBiology conference with Jacqueline Beaudry, Hoon-Ki Sung, and @sablesys.bsky.social!

📍Montreal, Canada
📅 August 19-20, 2025

Registration opens Jan 1, 2025. Mor info in the coming weeks.

Hope to see you there! @AdiposeBiology #AdiposeBiology2025
November 30, 2024 at 11:15 AM
Reposted by HaGe Sprenger
Need a detailed protocol for isolating and preparing extracellular fluids for proteomics? Find our step by step protocol here:

www.sciencedirect.com/science/arti...

@amandalsmythers.bsky.social
Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues
Communication between tissues or different cells within a tissue is often a result of secreted molecules such as metabolites, lipids, nucleic acids, o…
www.sciencedirect.com
November 18, 2024 at 10:34 AM