Guichard-Lab
@guichard-lab.bsky.social
Biomolecular and Foldamer Chemistry, #Peptide Engineering, Chemical Biology, Molecular and Structural Studies. Research group at CBMN in #Bordeaux, @iecb.bsky.social @cnrs.bsky.social @univbordeaux.bsky.social
Our website : http://www.guichard-iecb.fr
Our website : http://www.guichard-iecb.fr
Congrats @radha-tomar.bsky.social for winning the poster prize at the International Symposium on #foldamers 2025 🎉👏
Huge thanks to @andrecobb.bsky.social for organizing such an inspiring meeting at King’s College London! Great science & good vibes!
@foldnetuk.bsky.social @iecb.bsky.social
Huge thanks to @andrecobb.bsky.social for organizing such an inspiring meeting at King’s College London! Great science & good vibes!
@foldnetuk.bsky.social @iecb.bsky.social
Honored to win the Poster Prize at International Symposium on foldamer for my research on Foldamer catalysis.
Grateful for the recognition! @foldnetuk.bsky.social
Huge thanks to the Guichard group for their support !! @guichard-lab.bsky.social
Grateful for the recognition! @foldnetuk.bsky.social
Huge thanks to the Guichard group for their support !! @guichard-lab.bsky.social
September 17, 2025 at 8:13 PM
Congrats @radha-tomar.bsky.social for winning the poster prize at the International Symposium on #foldamers 2025 🎉👏
Huge thanks to @andrecobb.bsky.social for organizing such an inspiring meeting at King’s College London! Great science & good vibes!
@foldnetuk.bsky.social @iecb.bsky.social
Huge thanks to @andrecobb.bsky.social for organizing such an inspiring meeting at King’s College London! Great science & good vibes!
@foldnetuk.bsky.social @iecb.bsky.social
Reposted by Guichard-Lab
That’s a wrap! Huge thanks to our speakers, poster presenters, attendees, sponsors, organisers, @andrecobb.bsky.social, @anbismillah.bsky.social, @kingsnmes.bsky.social, EPSRC @ukri.org
See you at the next #Foldamers meeting in 2027 in Budapest at HUN-REN Research Centre for Natural Sciences
See you at the next #Foldamers meeting in 2027 in Budapest at HUN-REN Research Centre for Natural Sciences
September 3, 2025 at 5:37 PM
That’s a wrap! Huge thanks to our speakers, poster presenters, attendees, sponsors, organisers, @andrecobb.bsky.social, @anbismillah.bsky.social, @kingsnmes.bsky.social, EPSRC @ukri.org
See you at the next #Foldamers meeting in 2027 in Budapest at HUN-REN Research Centre for Natural Sciences
See you at the next #Foldamers meeting in 2027 in Budapest at HUN-REN Research Centre for Natural Sciences
Definitely planning to attend - Looking forward to reconnecting with the foldamer community in London !
There are still some places available for oral/poster presentations for the International Sympsium on Foldamers, and so we have extended the abstract deadline to 16th May. We also have a student rate now! Submit/sign up at www.foldamers2025.com - looking forward to seeing you!
May 20, 2025 at 9:24 PM
Definitely planning to attend - Looking forward to reconnecting with the foldamer community in London !
Reposted by Guichard-Lab
Great to see our paper on helicity-dependent peptide cyclizations online at the Journal of Peptide Science doi.org/10.1002/psc.... (open access)
Congrats to all authors!! #peptidomimetics
Congrats to all authors!! #peptidomimetics
April 28, 2025 at 8:31 AM
Great to see our paper on helicity-dependent peptide cyclizations online at the Journal of Peptide Science doi.org/10.1002/psc.... (open access)
Congrats to all authors!! #peptidomimetics
Congrats to all authors!! #peptidomimetics
Really enjoyed the Korean BBQ with colleagues and friends Prof. Hee-Seung Lee from KAIST and Prof. Sung Hyun Yoo from Chonnam National University yesterday after a full day at the KCS meeting. Great food and great company!
April 25, 2025 at 5:09 AM
Really enjoyed the Korean BBQ with colleagues and friends Prof. Hee-Seung Lee from KAIST and Prof. Sung Hyun Yoo from Chonnam National University yesterday after a full day at the KCS meeting. Great food and great company!
Excited to join 2025 Korean Chemical Society 135th General Meeting &Exhibition this week! Always a pleasure to catch up with colleagues and reconnect with lab alumni. Thank you, Sung Hyun @yoo-bios-lab.bsky.social for the fantastic welcome in Korea — truly appreciated!
@iecb.bsky.social
#ChemSky
@iecb.bsky.social
#ChemSky
April 24, 2025 at 3:18 PM
Excited to join 2025 Korean Chemical Society 135th General Meeting &Exhibition this week! Always a pleasure to catch up with colleagues and reconnect with lab alumni. Thank you, Sung Hyun @yoo-bios-lab.bsky.social for the fantastic welcome in Korea — truly appreciated!
@iecb.bsky.social
#ChemSky
@iecb.bsky.social
#ChemSky
Reposted by Guichard-Lab
We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!
April 14, 2025 at 8:57 AM
We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!
Reposted by Guichard-Lab
Join us this Friday, April 4th, for an afternoon minisymposium on protein structure and dynamics in disease! The place is as usual our IECB amphitheater!
March 31, 2025 at 12:32 PM
Join us this Friday, April 4th, for an afternoon minisymposium on protein structure and dynamics in disease! The place is as usual our IECB amphitheater!
Reposted by Guichard-Lab
What a superb and inspiring day, discussing highly diverse aspects of #Bioinspiration - A big thank to all the speakers, chairpersons, and the attendance. As well as the people involved in the organization...
Advances in Bioinspirations
@inserm.fr - @cea.fr - @cnrs.fr
#BMSV
Advances in Bioinspirations
@inserm.fr - @cea.fr - @cnrs.fr
#BMSV
March 28, 2025 at 4:30 PM
What a superb and inspiring day, discussing highly diverse aspects of #Bioinspiration - A big thank to all the speakers, chairpersons, and the attendance. As well as the people involved in the organization...
Advances in Bioinspirations
@inserm.fr - @cea.fr - @cnrs.fr
#BMSV
Advances in Bioinspirations
@inserm.fr - @cea.fr - @cnrs.fr
#BMSV
See our latest work on stapled peptide-foldamer hybrids targeting hDM2, using cis-4-mercaptoproline for an optimal macrocyclization. 🚀
@iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
#ChemBio #ChemSky
Read more: doi.org/10.1002/chem...
@iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
#ChemBio #ChemSky
Read more: doi.org/10.1002/chem...
March 24, 2025 at 2:53 PM
See our latest work on stapled peptide-foldamer hybrids targeting hDM2, using cis-4-mercaptoproline for an optimal macrocyclization. 🚀
@iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
#ChemBio #ChemSky
Read more: doi.org/10.1002/chem...
@iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
#ChemBio #ChemSky
Read more: doi.org/10.1002/chem...
Reposted by Guichard-Lab
Congratulations to Chloé Freyermuth on successfully defending her PhD! 🎉 I'm really proud to have her as the first PhD student in the lab @iecb.bsky.social @CBMN
A huge thank you to the members of the jury: Laurence Abrami, Agnès Rötig, Ed Tate, @ffriscourt.bsky.social, @guichard-lab.bsky.social
A huge thank you to the members of the jury: Laurence Abrami, Agnès Rötig, Ed Tate, @ffriscourt.bsky.social, @guichard-lab.bsky.social
March 14, 2025 at 10:49 AM
Congratulations to Chloé Freyermuth on successfully defending her PhD! 🎉 I'm really proud to have her as the first PhD student in the lab @iecb.bsky.social @CBMN
A huge thank you to the members of the jury: Laurence Abrami, Agnès Rötig, Ed Tate, @ffriscourt.bsky.social, @guichard-lab.bsky.social
A huge thank you to the members of the jury: Laurence Abrami, Agnès Rötig, Ed Tate, @ffriscourt.bsky.social, @guichard-lab.bsky.social
Reposted by Guichard-Lab
Congratulations to Jason Zhu on the publication of his manuscript "A β-Hairpin Peptide Derived from Aβ Forms Different Oligomers in the Crystal State and in Aqueous Solution" in Organic and Biomolecular Chemistry: pubs.rsc.org/en/content/a.... This
A β-Hairpin Peptide Derived from Aβ Forms Different Oligomers in the Crystal State and in Aqueous Solution
The supramolecular assembly of amyloid β into soluble oligomers is critical Alzheimer’s disease (AD) progression. Soluble Aβ oligomers have emerged as neurotoxic species involved in AD progression and...
pubs.rsc.org
March 5, 2025 at 6:30 AM
Congratulations to Jason Zhu on the publication of his manuscript "A β-Hairpin Peptide Derived from Aβ Forms Different Oligomers in the Crystal State and in Aqueous Solution" in Organic and Biomolecular Chemistry: pubs.rsc.org/en/content/a.... This
Reposted by Guichard-Lab
Just out: Stabilization of a miniprotein fold by an unpuckered proline surrogate
Stabilization of a miniprotein fold by an unpuckered proline surrogate
Communications Chemistry, Published online: 12 March 2025; doi:10.1038/s42004-025-01474-6Proline plays an important role in mediating protein folding and stability, however, the impact of noncanonical proline analogues on protein folding and stability is…
bit.ly
March 12, 2025 at 5:15 PM
Just out: Stabilization of a miniprotein fold by an unpuckered proline surrogate
Reposted by Guichard-Lab
Please check out our Angew. communication on DNA mimic foldamers that can outcompete DNA itself in the binding of proteins! 🧬
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
DNA Mimic Foldamer Recognition of a Chromosomal Protein
Biomolecular mimics are intended to outperform their natural counterparts. However, B-DNA surface mimicry to target DNA-binding proteins has long remained underdeveloped. We have introduced helical a...
onlinelibrary.wiley.com
February 27, 2025 at 10:31 AM
Please check out our Angew. communication on DNA mimic foldamers that can outcompete DNA itself in the binding of proteins! 🧬
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Reposted by Guichard-Lab
It was such a pleasure and privilege to have Prof Sabine Flitsch from Manchester university presenting today at our IECB seminar series @iecb.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
February 7, 2025 at 12:29 PM
It was such a pleasure and privilege to have Prof Sabine Flitsch from Manchester university presenting today at our IECB seminar series @iecb.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
Reposted by Guichard-Lab
Join us next week on Friday the 7th, at 11 am, in our IECB amphitheater to learn a whole lot on the design and applications of enzyme cascades for organic synthesis 🤓🧪👩🔬⚗️! Guest speaker Prof. Sabine Flitsch from the University of Manchester 🤩!!!
www.iecb.u-bordeaux.fr/evenements/i...
www.iecb.u-bordeaux.fr/evenements/i...
January 28, 2025 at 2:00 PM
Join us next week on Friday the 7th, at 11 am, in our IECB amphitheater to learn a whole lot on the design and applications of enzyme cascades for organic synthesis 🤓🧪👩🔬⚗️! Guest speaker Prof. Sabine Flitsch from the University of Manchester 🤩!!!
www.iecb.u-bordeaux.fr/evenements/i...
www.iecb.u-bordeaux.fr/evenements/i...
Happy to share our work on guanidinium-stapled peptides, now published in @angewandtechemie.bsky.social! A versatile method to stabilize peptide helices for precise protein surface recognition. Congrats to the team and special thanks to Morgane Pasco! 👏
🔗 doi.org/10.1002/anie...
@iecb.bsky.social
🔗 doi.org/10.1002/anie...
@iecb.bsky.social
January 3, 2025 at 8:56 AM
Happy to share our work on guanidinium-stapled peptides, now published in @angewandtechemie.bsky.social! A versatile method to stabilize peptide helices for precise protein surface recognition. Congrats to the team and special thanks to Morgane Pasco! 👏
🔗 doi.org/10.1002/anie...
@iecb.bsky.social
🔗 doi.org/10.1002/anie...
@iecb.bsky.social
Reposted by Guichard-Lab
2024 FDA approvals nature.com/articles/d41...
The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first MASH medicine and much more - find out about them in our annual round-up
The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first MASH medicine and much more - find out about them in our annual round-up
January 2, 2025 at 2:31 PM
2024 FDA approvals nature.com/articles/d41...
The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first MASH medicine and much more - find out about them in our annual round-up
The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first MASH medicine and much more - find out about them in our annual round-up
Reposted by Guichard-Lab
Happy New Year, ChemBio community! 🎉 In 2025, let’s advance chemical biology together: mobility grants to foster collaborations, training & mentoring for young scientists, and join us in Nantes (June 6-8) for our annual meeting. Free to join, spread the word! #GDRChemBio #ChemBio
January 1, 2025 at 9:03 AM
Happy New Year, ChemBio community! 🎉 In 2025, let’s advance chemical biology together: mobility grants to foster collaborations, training & mentoring for young scientists, and join us in Nantes (June 6-8) for our annual meeting. Free to join, spread the word! #GDRChemBio #ChemBio
Reposted by Guichard-Lab
Sir J. Fraser Stoddart, Chair Professor in Chemistry at the University of Hong Kong, died Dec. 30, 2024, at the age of 82. He was on holiday in Australia with his family. cen.acs.org/people/obitu... #chemsky
January 1, 2025 at 4:24 PM
Sir J. Fraser Stoddart, Chair Professor in Chemistry at the University of Hong Kong, died Dec. 30, 2024, at the age of 82. He was on holiday in Australia with his family. cen.acs.org/people/obitu... #chemsky
Reposted by Guichard-Lab
Check out our article in @angewandtechemie.bsky.social about the design of foldamers that aggregate into abiotic quaternary structures 🧩 Congrats to Shuhe! onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
December 18, 2024 at 3:32 PM
Check out our article in @angewandtechemie.bsky.social about the design of foldamers that aggregate into abiotic quaternary structures 🧩 Congrats to Shuhe! onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Guichard-Lab
Great to see so many familiar & new faces here!
Read on our biomimetic design strategies: www.thieme-connect.com/products/ejo...
👉 #proteomimetics for challenging targets
👉 #INCYPRO chemical #proteinengineering
👉 covalent #peptidomimetics inhibitors
Big thanks to all former & present group members!
Read on our biomimetic design strategies: www.thieme-connect.com/products/ejo...
👉 #proteomimetics for challenging targets
👉 #INCYPRO chemical #proteinengineering
👉 covalent #peptidomimetics inhibitors
Big thanks to all former & present group members!
December 11, 2024 at 3:51 PM
Great to see so many familiar & new faces here!
Read on our biomimetic design strategies: www.thieme-connect.com/products/ejo...
👉 #proteomimetics for challenging targets
👉 #INCYPRO chemical #proteinengineering
👉 covalent #peptidomimetics inhibitors
Big thanks to all former & present group members!
Read on our biomimetic design strategies: www.thieme-connect.com/products/ejo...
👉 #proteomimetics for challenging targets
👉 #INCYPRO chemical #proteinengineering
👉 covalent #peptidomimetics inhibitors
Big thanks to all former & present group members!
Reposted by Guichard-Lab
Congratulations to our @iecb.bsky.social and MFP colleague Nicolas Reyes for his medal from the French académie des sciences (médaille de la section de Biologie moléculaire et cellulaire, génomique).
@univbordeaux.bsky.social @cnrs.bsky.social
@univbordeaux.bsky.social @cnrs.bsky.social
November 28, 2024 at 4:26 PM
Congratulations to our @iecb.bsky.social and MFP colleague Nicolas Reyes for his medal from the French académie des sciences (médaille de la section de Biologie moléculaire et cellulaire, génomique).
@univbordeaux.bsky.social @cnrs.bsky.social
@univbordeaux.bsky.social @cnrs.bsky.social
Reposted by Guichard-Lab
Great to meet the #chembio community from Bordeaux (France) for the Chemistry Biology Interface Day (CBID 2024) today!
Congratulations to Cléo Chidaine (ARNA) and Melissa Kosovari (CBMN) on winning the poster prizes!
Thanks to @univbordeaux.bsky.social and @iecb.bsky.social for sponsoring/hosting
Congratulations to Cléo Chidaine (ARNA) and Melissa Kosovari (CBMN) on winning the poster prizes!
Thanks to @univbordeaux.bsky.social and @iecb.bsky.social for sponsoring/hosting
November 26, 2024 at 9:32 PM
Great to meet the #chembio community from Bordeaux (France) for the Chemistry Biology Interface Day (CBID 2024) today!
Congratulations to Cléo Chidaine (ARNA) and Melissa Kosovari (CBMN) on winning the poster prizes!
Thanks to @univbordeaux.bsky.social and @iecb.bsky.social for sponsoring/hosting
Congratulations to Cléo Chidaine (ARNA) and Melissa Kosovari (CBMN) on winning the poster prizes!
Thanks to @univbordeaux.bsky.social and @iecb.bsky.social for sponsoring/hosting
Reposted by Guichard-Lab
Join us next Thursday (Nov 21) for our 'Membrane-Interacting Peptides & Multiscale Biophysics' symposium organized in honor of Dr. Frances Separovic from the University of Melbourne and her award of the title Doctor Honoris Causa from the University of Bordeaux 👏👏👏!
November 13, 2024 at 8:47 AM
Join us next Thursday (Nov 21) for our 'Membrane-Interacting Peptides & Multiscale Biophysics' symposium organized in honor of Dr. Frances Separovic from the University of Melbourne and her award of the title Doctor Honoris Causa from the University of Bordeaux 👏👏👏!