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guichard-lab.bsky.social
Guichard-Lab
@guichard-lab.bsky.social
370 followers 390 following 9 posts
Biomolecular and Foldamer Chemistry, #Peptide Engineering, Chemical Biology, Molecular and Structural Studies. Research group at CBMN in #Bordeaux, @iecb.bsky.social @cnrs.bsky.social @univbordeaux.bsky.social
Our website : http://www.guichard-iecb.fr
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guichard-lab.bsky.social
Really enjoyed the Korean BBQ with colleagues and friends Prof. Hee-Seung Lee from KAIST and Prof. Sung Hyun Yoo from Chonnam National University yesterday after a full day at the KCS meeting. Great food and great company!
April 25, 2025 at 5:09 AM
guichard-lab.bsky.social
Excited to join 2025 Korean Chemical Society 135th General Meeting &Exhibition this week! Always a pleasure to catch up with colleagues and reconnect with lab alumni. Thank you, Sung Hyun @yoo-bios-lab.bsky.social for the fantastic welcome in Korea — truly appreciated!
@iecb.bsky.social
#ChemSky
April 24, 2025 at 3:18 PM
guichard-lab.bsky.social
See our latest work on stapled peptide-foldamer hybrids targeting hDM2, using cis-4-mercaptoproline for an optimal macrocyclization. 🚀
@iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social
#ChemBio #ChemSky
Read more: doi.org/10.1002/chem...
Co-crystal structure of a macrocyclic foldamer-peptide hybrid (8a) bound to hDM2 (PDB ID 9GFK)
March 24, 2025 at 2:53 PM
guichard-lab.bsky.social
Happy to share our work on guanidinium-stapled peptides, now published in @angewandtechemie.bsky.social! A versatile method to stabilize peptide helices for precise protein surface recognition. Congrats to the team and special thanks to Morgane Pasco! 👏
🔗 doi.org/10.1002/anie...
@iecb.bsky.social
Guanidinium‐Stapled Helical Peptides for Targeting Protein‐Protein Interactions Peptide stapling has emerged as a versatile approach in drug discovery to reinforce secondary structure elements especially α-helices and improve properties of linear…
January 3, 2025 at 8:56 AM