Timme-Laragy Lab
@fishytox.bsky.social
Developmental toxicology, redox biology, zebrafish. Team T-L!
Reposted by Timme-Laragy Lab
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
August 11, 2025 at 11:54 AM
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
Reposted by Timme-Laragy Lab
Big misalignment between #MAHA
(Make America Healthy Again) statements and slashed funding of research, which can damage this important field for a long time (pollution research) 🔽
(Make America Healthy Again) statements and slashed funding of research, which can damage this important field for a long time (pollution research) 🔽
Was one of several scientists interviewed on All Things Considered yesterday evening about the misalignment between continued funding cuts to research on chemicals and the MAHA agenda.
www.npr.org/2025/06/03/n...
@pnwmicroplastics.bsky.social
@oregonstate.edu
@npr.org
www.npr.org/2025/06/03/n...
@pnwmicroplastics.bsky.social
@oregonstate.edu
@npr.org
Research cuts conflict with MAHA's stated goals
Health Secretary Robert F. Kennedy Jr. is calling for efforts to limit Americans' exposure to toxic substances. But the Trump administration is also taking actions that run counter to this goal.
www.npr.org
June 5, 2025 at 7:47 AM
Big misalignment between #MAHA
(Make America Healthy Again) statements and slashed funding of research, which can damage this important field for a long time (pollution research) 🔽
(Make America Healthy Again) statements and slashed funding of research, which can damage this important field for a long time (pollution research) 🔽
Reposted by Timme-Laragy Lab
NSF Physics was cut by 85%, basically wiping out most of its capacity for supporting research.
NSF Astronomy was cut by 53%
Undergrad education was cut by 71% and research on learning by 79%
Graduate education was cut by 100% to ZERO.
#GiftLink ⚛️🔭
www.nytimes.com/interactive/...
NSF Astronomy was cut by 53%
Undergrad education was cut by 71% and research on learning by 79%
Graduate education was cut by 100% to ZERO.
#GiftLink ⚛️🔭
www.nytimes.com/interactive/...
Trump Has Cut Science Funding to Its Lowest Level in Decades (Gift Article)
The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.
www.nytimes.com
May 22, 2025 at 3:34 PM
NSF Physics was cut by 85%, basically wiping out most of its capacity for supporting research.
NSF Astronomy was cut by 53%
Undergrad education was cut by 71% and research on learning by 79%
Graduate education was cut by 100% to ZERO.
#GiftLink ⚛️🔭
www.nytimes.com/interactive/...
NSF Astronomy was cut by 53%
Undergrad education was cut by 71% and research on learning by 79%
Graduate education was cut by 100% to ZERO.
#GiftLink ⚛️🔭
www.nytimes.com/interactive/...
Reposted by Timme-Laragy Lab
Trump’s proposed $23 billion in cuts to NIH & NSF could cost the U.S. economy at least $10 billion a year, according to new research. Public science funding drives innovation, productivity, and long-term growth. Slashing it isn’t saving money; it’s losing our future. www.forbes.com/sites/johndr...
Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually
Economists find public R&D drives a quarter of U.S. productivity growth — and pays for itself
www.forbes.com
May 19, 2025 at 4:47 PM
Trump’s proposed $23 billion in cuts to NIH & NSF could cost the U.S. economy at least $10 billion a year, according to new research. Public science funding drives innovation, productivity, and long-term growth. Slashing it isn’t saving money; it’s losing our future. www.forbes.com/sites/johndr...
Reposted by Timme-Laragy Lab
Attention ZDMS Members and greater fish community:
A message from the Local Organizing Committee for #ZDM18!
The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)
A message from the Local Organizing Committee for #ZDM18!
The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)
May 7, 2025 at 11:54 AM
Attention ZDMS Members and greater fish community:
A message from the Local Organizing Committee for #ZDM18!
The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)
A message from the Local Organizing Committee for #ZDM18!
The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)
Reposted by Timme-Laragy Lab
Bluetorial: My NIH grant got funded; The money is in the bank
What happens behind the scenes with NIH fund transfers
What happens behind the scenes with NIH fund transfers
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
March 12, 2025 at 9:50 AM
Bluetorial: My NIH grant got funded; The money is in the bank
What happens behind the scenes with NIH fund transfers
What happens behind the scenes with NIH fund transfers
Reposted by Timme-Laragy Lab
As we learn Gene Hackman had severe Alzheimer’s, we find out that Trump and Musk are killing research into Alzheimer’s cures.
The Trump/Musk crime spree has to be stopped. Get their hands off our government.
The Trump/Musk crime spree has to be stopped. Get their hands off our government.
🧪The Alzheimer's Disease Research Center program is a crown jewel in the NIA's funding portfolio. 35 centers in red, blue and purple states put data in a single repository working towards a shared goal of curing AD. Funding for center renewals is on hold.
tinyurl.com/yc2pr626
#standupforscience2025
tinyurl.com/yc2pr626
#standupforscience2025
March 8, 2025 at 1:43 PM
As we learn Gene Hackman had severe Alzheimer’s, we find out that Trump and Musk are killing research into Alzheimer’s cures.
The Trump/Musk crime spree has to be stopped. Get their hands off our government.
The Trump/Musk crime spree has to be stopped. Get their hands off our government.
Reposted by Timme-Laragy Lab
Did you know the last common ancestor of #zebrafish & humans was ~450 million years ago? A whole genome duplication event (3R) occurred early in the teleost fish phylogeny. Despite this event, zebrafish & humans have about the same number of chromosomes (25 & 23, respectively). #ZebrafishFunFacts 🧪
March 8, 2025 at 5:53 PM
Did you know the last common ancestor of #zebrafish & humans was ~450 million years ago? A whole genome duplication event (3R) occurred early in the teleost fish phylogeny. Despite this event, zebrafish & humans have about the same number of chromosomes (25 & 23, respectively). #ZebrafishFunFacts 🧪
Reposted by Timme-Laragy Lab
For more information about the 2025 Gordon Research Conference (GRC) and trainee-led Seminar (GRS), please check out our website:
www.grc.org/cellular-and...
We hope you'll join us in August!
www.grc.org/cellular-and...
We hope you'll join us in August!
2025 Cellular and Molecular Mechanisms of Toxicity Conference GRC
The 2025 Gordon Research Conference on Cellular and Molecular Mechanisms of Toxicity will be held in Andover, New Hampshire. Apply today to reserve your spot.
www.grc.org
March 4, 2025 at 6:02 PM
For more information about the 2025 Gordon Research Conference (GRC) and trainee-led Seminar (GRS), please check out our website:
www.grc.org/cellular-and...
We hope you'll join us in August!
www.grc.org/cellular-and...
We hope you'll join us in August!
Reposted by Timme-Laragy Lab
Our next extraordinary biologist this week is Daniel Gorelick, current Editor-in-Chief of @biologyopen.bsky.social and Associate Professor at @bcmhouston.bsky.social, USA. To know more about Dan’s visions for BiO, read this Editorial: doi.org/10.1242/bio.....
#100biologists
#100biologists
February 27, 2025 at 11:30 AM
Our next extraordinary biologist this week is Daniel Gorelick, current Editor-in-Chief of @biologyopen.bsky.social and Associate Professor at @bcmhouston.bsky.social, USA. To know more about Dan’s visions for BiO, read this Editorial: doi.org/10.1242/bio.....
#100biologists
#100biologists
Reposted by Timme-Laragy Lab
[Meeting]
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA
#zebrafish
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA
#zebrafish
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA - Meetings - Confluence
zfin.atlassian.net
February 27, 2025 at 7:39 PM
[Meeting]
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA
#zebrafish
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA
#zebrafish
Reposted by Timme-Laragy Lab
Your regular reminder that the US air & water pollution laws passed in the 60s & 70s -- and the elaborate federal bureaucracy created to administer them -- constitute one of the most successful gov't interventions in history. WILDLY successful. The envy of the world.
February 24, 2025 at 6:43 PM
Your regular reminder that the US air & water pollution laws passed in the 60s & 70s -- and the elaborate federal bureaucracy created to administer them -- constitute one of the most successful gov't interventions in history. WILDLY successful. The envy of the world.
Reposted by Timme-Laragy Lab
We’ve landed on BlueSky!
Excited to join the conversation and bring you the latest SOT news, toxicology updates, and more! Stay tuned for insightful research, event highlights, ways to connect with the SOT community, and more! #Toxicology #ScienceMatters #SOT
Excited to join the conversation and bring you the latest SOT news, toxicology updates, and more! Stay tuned for insightful research, event highlights, ways to connect with the SOT community, and more! #Toxicology #ScienceMatters #SOT
February 20, 2025 at 4:43 PM
We’ve landed on BlueSky!
Excited to join the conversation and bring you the latest SOT news, toxicology updates, and more! Stay tuned for insightful research, event highlights, ways to connect with the SOT community, and more! #Toxicology #ScienceMatters #SOT
Excited to join the conversation and bring you the latest SOT news, toxicology updates, and more! Stay tuned for insightful research, event highlights, ways to connect with the SOT community, and more! #Toxicology #ScienceMatters #SOT
Reposted by Timme-Laragy Lab
Nature Story "Revealed: NIH research grants still frozen despite lawsuits challenging Trump order"
(with non-paywalled link)
archive.ph/7h6Im
(with non-paywalled link)
archive.ph/7h6Im
archive.ph
February 20, 2025 at 11:17 PM
Nature Story "Revealed: NIH research grants still frozen despite lawsuits challenging Trump order"
(with non-paywalled link)
archive.ph/7h6Im
(with non-paywalled link)
archive.ph/7h6Im
Reposted by Timme-Laragy Lab
Toughest fish on Earth? Mummichogs are a euryhaline species, which means they can survive a range of salinities from freshwater to water that has 110g salt/L. Heralded as the first fish species in outer space, they even evolved resistance to toxic chemicals that would kill other fish. #TeleostTalk 🧪
February 8, 2025 at 11:19 AM
Toughest fish on Earth? Mummichogs are a euryhaline species, which means they can survive a range of salinities from freshwater to water that has 110g salt/L. Heralded as the first fish species in outer space, they even evolved resistance to toxic chemicals that would kill other fish. #TeleostTalk 🧪
Reposted by Timme-Laragy Lab
This is really bleak, they're attacking all animal research with the ranking Democrat, Shantel Brown, agreeing with Nancy Mace. Brown goes on to state that AI and 3D printing give us "better and more accurate results" compared to actual biology.
At this point I think it's safe to assume my name is on a list somewhere for one reason or another related to my being transsexual. So, no use in radio silence.
In 30m, I'll be watching Nancy Mace's hearing on our preclinical trans health research to see how my life is about to change (derogatory).
In 30m, I'll be watching Nancy Mace's hearing on our preclinical trans health research to see how my life is about to change (derogatory).
It’s a once in a lifetime opportunity to have your research being discussed in the halls of Congress except in classic Tragic Troy syndrome it’s because they want to stop you from doing it.
February 6, 2025 at 7:17 PM
This is really bleak, they're attacking all animal research with the ranking Democrat, Shantel Brown, agreeing with Nancy Mace. Brown goes on to state that AI and 3D printing give us "better and more accurate results" compared to actual biology.
Reposted by Timme-Laragy Lab
A depressing question with a lot of great answers. We need #devbio to understand birth defects, cancer, stem cell biology (and the resultant therapeutics) and so much more. And, frankly, because it's just amazing how a single cell can make a complex organism.
#devbio what arguments do you use when your colleagues suggest devbio isn't useful anymore and shouldn't be required in coursework?
February 4, 2025 at 9:12 AM
A depressing question with a lot of great answers. We need #devbio to understand birth defects, cancer, stem cell biology (and the resultant therapeutics) and so much more. And, frankly, because it's just amazing how a single cell can make a complex organism.
Reposted by Timme-Laragy Lab
Right here. I'm fascinated by how it all manages to go well, but also how it can go wrong. If we can bring answers to any families dealing with congenital anomalies, it will be worth it.
Birth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5
wisqars.cdc.gov/pdfs/leading...
wisqars.cdc.gov/pdfs/leading...
February 5, 2025 at 3:43 AM
Right here. I'm fascinated by how it all manages to go well, but also how it can go wrong. If we can bring answers to any families dealing with congenital anomalies, it will be worth it.
Reposted by Timme-Laragy Lab
I'm thrilled to announce that our paper describing Marigold, a free machine learning-based webapp for zebrafish behavioral analysis, is officially published! Marigold features a user friendly graphical user interface to enable training of a neural network for analyzing behavioral recordings.
January 28, 2025 at 4:23 PM
I'm thrilled to announce that our paper describing Marigold, a free machine learning-based webapp for zebrafish behavioral analysis, is officially published! Marigold features a user friendly graphical user interface to enable training of a neural network for analyzing behavioral recordings.
Reposted by Timme-Laragy Lab
We are so excited to share our latest manuscript containing a multidimensional PFAS database with LC retention times, IMS collision cross sections (CCS) and MS characteristics for 175 PFAS and their 281 resulting ion types! We hope it helps others!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS) - Scientific Data
Scientific Data - Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS)
www.nature.com
January 27, 2025 at 6:48 PM
We are so excited to share our latest manuscript containing a multidimensional PFAS database with LC retention times, IMS collision cross sections (CCS) and MS characteristics for 175 PFAS and their 281 resulting ion types! We hope it helps others!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Timme-Laragy Lab
Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
January 26, 2025 at 12:13 AM
Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
Reposted by Timme-Laragy Lab
Instead of lowering prices, the Trump Administration is disrupting the work of researchers who are studying life-saving medicines and treatments.
Scientists at NIH can’t purchase supplies for their studies after Trump administration pauses outside communications | CNN
Scientists at the National Institutes of Health have been told the communications pause announced by the Trump Administration earlier this week includes a pause on all purchasing, including supplies f...
www.cnn.com
January 25, 2025 at 1:47 PM
Instead of lowering prices, the Trump Administration is disrupting the work of researchers who are studying life-saving medicines and treatments.
Reposted by Timme-Laragy Lab
Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH
Trump's NIH Freeze Puts Scientific Research at Risk
America’s best scientific minds are scrambling to determine the impact of the disruption.
www.bloomberg.com
January 24, 2025 at 9:28 PM
Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH
Reposted by Timme-Laragy Lab
The Trump administration has canceled meetings and frozen hiring at the NIH.
In today’s episode, @casey_crownhart joins us to discuss this and other other big science stories of the week. Plus, what is a meme coin?
Listen here 🎧: https://buff.ly/3Mut28J
In today’s episode, @casey_crownhart joins us to discuss this and other other big science stories of the week. Plus, what is a meme coin?
Listen here 🎧: https://buff.ly/3Mut28J
January 24, 2025 at 9:32 PM
The Trump administration has canceled meetings and frozen hiring at the NIH.
In today’s episode, @casey_crownhart joins us to discuss this and other other big science stories of the week. Plus, what is a meme coin?
Listen here 🎧: https://buff.ly/3Mut28J
In today’s episode, @casey_crownhart joins us to discuss this and other other big science stories of the week. Plus, what is a meme coin?
Listen here 🎧: https://buff.ly/3Mut28J
Reposted by Timme-Laragy Lab
If you had a study section or similar NIH travel canceled, or indeed if you have not, can you reply with the dates of the meeting and whether it's on or not? Would be good to get a sense of what time period this applies to for now (esp if NIH is muzzled and can't announce it...)
January 23, 2025 at 12:26 AM
If you had a study section or similar NIH travel canceled, or indeed if you have not, can you reply with the dates of the meeting and whether it's on or not? Would be good to get a sense of what time period this applies to for now (esp if NIH is muzzled and can't announce it...)