"a fascinating case study on the limits of AI in biology and the harms of current publishing incentives" rachel.fast.ai/posts/2025-0...

We're delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases in @science.org , led by @jonaskoeppel.bsky.social , @f-raphael.bsky.social , with @proftomellis.bsky.social and George Church.
www.science.org/doi/10.1126/...

Why Pigeons Make Bad Nests: A defense of pigeon aesthetics

"Priority" was only used in the singular form until the mid-20th century books.google.com/ngrams/graph...

Lloyd Armbrust (face mask entrepreneur & manufacturer based in Austin) posted that he has nearly a truckload of free American-made N95s if anyone in Los Angeles or in Southern California needs them. He's a good guy. armbrust.com. He posts mask updates on X & can be messaged there too #LAFire

This is Hazelnut. She is both teeny tiny and comfy cozy. Dynamite combo. 12/10

AI investor Dylan Reid of Zetta Ventures (Noetik & Nabla are in portfolio) posted in advance of #JPM25 on what he's paying attention to in life sci incl Data Generation-as-a-Service, Open Source Wars, Multiscale Models & "Agents Everywhere (but the Lab)" www.linkedin.com/posts/deploy... #biosky

Milo has made the top of the fridge his favorite spot, perhaps based on a nearby heating vent. Moreover Milo is to be congratulated for dropping below 20 pounds on his diet and therefore less likely to damage the fridge. He feels deprived tho.

Sometimes my pet peeve is when the casual gene is NOT the closest gene.

May I introduce you to HERC2,
reported here for the trait "retinal pigment score" with a pvalue of 0 (?!)

www.nature.com/articles/s41...

Beautiful work led by Maya Arce from Marson lab reveals a fascinating story about rewiring of a critical gene regulatory circuit in different T cell types: T effectors and Tregs
www.nature.com/articles/s41...

As Hyperloop One shuts down, we need to remember that the Hyperloop was never meant to be built.

Elon Musk’s goal was never to transform transportation for the masses, but to stop or delay high-speed rail from reaching North America. Sadly, he succeeded — and we all lost as a result.

Lowering the Bar has a list of funny case names. A number of them stem from the defendant being listed as the property when the government is confiscating it but it does make you wonder about why. www.loweringthebar.net/comical-case...