fireflypotion.bsky.social
fireflypotion.bsky.social
@fireflypotion.bsky.social
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"a fascinating case study on the limits of AI in biology and the harms of current publishing incentives" rachel.fast.ai/posts/2025-0...
Rachel Thomas, PhD - Deep learning gets the glory, deep fact checking gets ignored
an AI researcher going back to school for immunology
rachel.fast.ai
June 4, 2025 at 3:53 PM
Reposted by fireflypotion.bsky.social
We're delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases in @science.org , led by @jonaskoeppel.bsky.social , @f-raphael.bsky.social , with @proftomellis.bsky.social and George Church.
www.science.org/doi/10.1126/...
Randomizing the human genome by engineering recombination between repeat elements
We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to insert recombination handles into re...
www.science.org
January 31, 2025 at 1:49 PM
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Why Pigeons Make Bad Nests: A defense of pigeon aesthetics
January 13, 2025 at 3:00 PM
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"Priority" was only used in the singular form until the mid-20th century books.google.com/ngrams/graph...
January 11, 2025 at 1:04 PM
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Lloyd Armbrust (face mask entrepreneur & manufacturer based in Austin) posted that he has nearly a truckload of free American-made N95s if anyone in Los Angeles or in Southern California needs them. He's a good guy. armbrust.com. He posts mask updates on X & can be messaged there too #LAFire
January 8, 2025 at 5:02 AM
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This is Hazelnut. She is both teeny tiny and comfy cozy. Dynamite combo. 12/10
January 6, 2025 at 11:11 PM
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AI investor Dylan Reid of Zetta Ventures (Noetik & Nabla are in portfolio) posted in advance of #JPM25 on what he's paying attention to in life sci incl Data Generation-as-a-Service, Open Source Wars, Multiscale Models & "Agents Everywhere (but the Lab)" www.linkedin.com/posts/deploy... #biosky
Dylan Reid on LinkedIn: It’s almost JPM which means it's prediction time 🔮 ✨ 2024 was a BIG year… | 29 comments
It’s almost JPM which means it's prediction time 🔮 ✨ 2024 was a BIG year for AI in the life sciences: We saw the first “generative” drugs go into the clinic… | 29 comments on LinkedIn
www.linkedin.com
January 6, 2025 at 9:34 PM
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Milo has made the top of the fridge his favorite spot, perhaps based on a nearby heating vent. Moreover Milo is to be congratulated for dropping below 20 pounds on his diet and therefore less likely to damage the fridge. He feels deprived tho.
January 7, 2025 at 6:07 PM
Reposted by fireflypotion.bsky.social
Sometimes my pet peeve is when the casual gene is NOT the closest gene.

May I introduce you to HERC2,
reported here for the trait "retinal pigment score" with a pvalue of 0 (?!)

www.nature.com/articles/s41...
January 7, 2025 at 10:50 PM
Reposted by fireflypotion.bsky.social
Beautiful work led by Maya Arce from Marson lab reveals a fascinating story about rewiring of a critical gene regulatory circuit in different T cell types: T effectors and Tregs
www.nature.com/articles/s41...
Central control of dynamic gene circuits governs T cell rest and activation - Nature
Resting and activated T cell states are established by context-specific regulators and dynamic gene circuits.
www.nature.com
December 11, 2024 at 8:46 PM
Reposted by fireflypotion.bsky.social
As Hyperloop One shuts down, we need to remember that the Hyperloop was never meant to be built.

Elon Musk’s goal was never to transform transportation for the masses, but to stop or delay high-speed rail from reaching North America. Sadly, he succeeded — and we all lost as a result.
The Hyperloop was always a scam
It's time to be honest about Musk's vacuum tube to nowhere
www.disconnect.blog
December 22, 2023 at 2:51 PM
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Lowering the Bar has a list of funny case names. A number of them stem from the defendant being listed as the property when the government is confiscating it but it does make you wonder about why. www.loweringthebar.net/comical-case...
Comical Case Names
In alphabetical order: 4 Exotic Dancers v. Spearmint Rhino and the Wild Goose, et al., No. CV 08-4038 ABC, 2009 WL 250054 (C.D. Cal. Jan. 29, 2009) (denying plaintiffs’ motion for leave to pr…
www.loweringthebar.net
December 11, 2023 at 11:44 AM