Dylan Roskams-Edris
@dylan-re.bsky.social
Father of cats, reader of books, breaker of dance, husband of adequacy, lover of nature, watcher of birds, opener of science.
He/Him
Day job - Network Lead, Education and Events @conscience-network.bsky.social
Photo by Jesse Milns, Toronto
He/Him
Day job - Network Lead, Education and Events @conscience-network.bsky.social
Photo by Jesse Milns, Toronto
Reposted by Dylan Roskams-Edris
This is from The Tonight Show with Johnny Carson aired on May 20th, 1977.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
April 30, 2025 at 1:12 PM
This is from The Tonight Show with Johnny Carson aired on May 20th, 1977.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Reposted by Dylan Roskams-Edris
Reposted by Dylan Roskams-Edris
This is the moment we've worked toward for a long time: First public disclosure of the @asapdiscovery.bsky.social pan-coronavirus antiviral aiming to help keep humanity safe from future pandemic threats like MERS-CoV and other bat coronaviruses.
📢Important announcement! Today, the @asapdiscovery.bsky.social consortium disclosed the structure of our preclinical candidate, ASAP-0017445, a promising broad-spectrum antiviral with potent activity against SARS-CoV2 and other viruses belonging to the same family. (1/10)
March 25, 2025 at 7:47 PM
This is the moment we've worked toward for a long time: First public disclosure of the @asapdiscovery.bsky.social pan-coronavirus antiviral aiming to help keep humanity safe from future pandemic threats like MERS-CoV and other bat coronaviruses.
Reposted by Dylan Roskams-Edris
What it's like inside the NIH under current conditions: not good. Terrible uncertainty and low morale, and an inability to order even basic materials because of trouble with the purchasing department:
The Continuing Crisis, Part IX: Inside the NIH Now
www.science.org
March 19, 2025 at 5:30 PM
What it's like inside the NIH under current conditions: not good. Terrible uncertainty and low morale, and an inability to order even basic materials because of trouble with the purchasing department:
Reposted by Dylan Roskams-Edris
✨Symposium session reveal✨ Featuring @albertantolin.bsky.social and @karmencj.bsky.social, this session highlights initiatives enabling communities to come together to solve some of the biggest challenges in drug discovery. Register here: conscience.ca/symposium2025
February 11, 2025 at 9:04 PM
✨Symposium session reveal✨ Featuring @albertantolin.bsky.social and @karmencj.bsky.social, this session highlights initiatives enabling communities to come together to solve some of the biggest challenges in drug discovery. Register here: conscience.ca/symposium2025
Reposted by Dylan Roskams-Edris
We are uniting experts in ML, computational chemistry, and drug discovery to get hands-on experience with AIRCHECK. Co-developed by SGC and @uhntoronto.bsky.social, AIRCHECK is an open data platform designed to enhance predictive models in drug discovery.
event.fourwaves.com/aircheckwork...
event.fourwaves.com/aircheckwork...
February 5, 2025 at 2:45 PM
We are uniting experts in ML, computational chemistry, and drug discovery to get hands-on experience with AIRCHECK. Co-developed by SGC and @uhntoronto.bsky.social, AIRCHECK is an open data platform designed to enhance predictive models in drug discovery.
event.fourwaves.com/aircheckwork...
event.fourwaves.com/aircheckwork...
Reposted by Dylan Roskams-Edris
I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War.
Same link, new title and some updates.
Same link, new title and some updates.
Revised and Extended: What's Happening Inside the NIH and NSF
www.science.org
February 5, 2025 at 5:17 PM
I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War.
Same link, new title and some updates.
Same link, new title and some updates.
Reposted by Dylan Roskams-Edris
More than 25 years after FXR agonist GW4604 was described by now @thesgc.bsky.social scientist Tim Willson, it is still being used in cutting edge papers. High quality #ChemicalProbes are expensive to discover, but they’re the gift that keeps on giving.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Host metabolism balances microbial regulation of bile acid signalling - Nature
A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.
www.nature.com
February 5, 2025 at 6:20 PM
More than 25 years after FXR agonist GW4604 was described by now @thesgc.bsky.social scientist Tim Willson, it is still being used in cutting edge papers. High quality #ChemicalProbes are expensive to discover, but they’re the gift that keeps on giving.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Dylan Roskams-Edris
A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it.
www.science.org/content/blog...
www.science.org/content/blog...
What's Happening Inside the NIH and NSF
www.science.org
February 4, 2025 at 4:40 PM
A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it.
www.science.org/content/blog...
www.science.org/content/blog...
Reposted by Dylan Roskams-Edris
Reposted by Dylan Roskams-Edris
While we gear up to welcome both Polaris and ASAP to our Symposium in April, they have been cooking up something special.
They're releasing an intermediate leaderboard for the antiviral challenge on the 31st. So you (looking at #CACHEChallenge participants!) have a few days to get in a prediction!
They're releasing an intermediate leaderboard for the antiviral challenge on the 31st. So you (looking at #CACHEChallenge participants!) have a few days to get in a prediction!
📣 We heard your feedback! We’ll be putting all results submitted by Jan 31st on an intermediate leaderboard so you can see how you rank across other participants in the antiviral challenge.
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
January 27, 2025 at 7:31 PM
While we gear up to welcome both Polaris and ASAP to our Symposium in April, they have been cooking up something special.
They're releasing an intermediate leaderboard for the antiviral challenge on the 31st. So you (looking at #CACHEChallenge participants!) have a few days to get in a prediction!
They're releasing an intermediate leaderboard for the antiviral challenge on the 31st. So you (looking at #CACHEChallenge participants!) have a few days to get in a prediction!
Reposted by Dylan Roskams-Edris
📣 We heard your feedback! We’ll be putting all results submitted by Jan 31st on an intermediate leaderboard so you can see how you rank across other participants in the antiviral challenge.
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
January 23, 2025 at 4:24 PM
📣 We heard your feedback! We’ll be putting all results submitted by Jan 31st on an intermediate leaderboard so you can see how you rank across other participants in the antiviral challenge.
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
Ready to put your predictions to the test?
📨 Submit your results today: polarishub.io/competitions
Reposted by Dylan Roskams-Edris
Are you working to advance #OpenScience, #AI -assisted drug design, or innovative approaches to #DrugDiscovery? Submit an abstract by March 7 for the opportunity to present a 3-minute flash talk at the Conscience Symposium on Open Drug Discovery on April 7-8, 2025, in Montreal!
January 15, 2025 at 8:56 PM
Are you working to advance #OpenScience, #AI -assisted drug design, or innovative approaches to #DrugDiscovery? Submit an abstract by March 7 for the opportunity to present a 3-minute flash talk at the Conscience Symposium on Open Drug Discovery on April 7-8, 2025, in Montreal!
Reposted by Dylan Roskams-Edris
Interested in building the future of open source ligand- and structure-based ML models for ADMET prediction?
The ARPA-H funded OMSF (@omsf.bsky.social) OpenADMET project is hiring multiple positions to build ML models of ADMET properties and drive informative data collection!
openadmet.org/jobs/
The ARPA-H funded OMSF (@omsf.bsky.social) OpenADMET project is hiring multiple positions to build ML models of ADMET properties and drive informative data collection!
openadmet.org/jobs/
OpenADMET Jobs
Seeking talented scientists for the OpenADMET Consortium
openadmet.org
January 8, 2025 at 3:41 PM
Interested in building the future of open source ligand- and structure-based ML models for ADMET prediction?
The ARPA-H funded OMSF (@omsf.bsky.social) OpenADMET project is hiring multiple positions to build ML models of ADMET properties and drive informative data collection!
openadmet.org/jobs/
The ARPA-H funded OMSF (@omsf.bsky.social) OpenADMET project is hiring multiple positions to build ML models of ADMET properties and drive informative data collection!
openadmet.org/jobs/
Enjoyed this accessible talk by Head of Data at
@asterainstitute.bsky.social and @conscience-network.bsky.social board member John Wilbanks
It's the type of quality, down to earth advice and insight that only comes from decades of careful thought and really caring.
www.youtube.com/watch?v=4Xnl...
@asterainstitute.bsky.social and @conscience-network.bsky.social board member John Wilbanks
It's the type of quality, down to earth advice and insight that only comes from decades of careful thought and really caring.
www.youtube.com/watch?v=4Xnl...
www.youtube.com
January 3, 2025 at 10:29 PM
Enjoyed this accessible talk by Head of Data at
@asterainstitute.bsky.social and @conscience-network.bsky.social board member John Wilbanks
It's the type of quality, down to earth advice and insight that only comes from decades of careful thought and really caring.
www.youtube.com/watch?v=4Xnl...
@asterainstitute.bsky.social and @conscience-network.bsky.social board member John Wilbanks
It's the type of quality, down to earth advice and insight that only comes from decades of careful thought and really caring.
www.youtube.com/watch?v=4Xnl...
Reposted by Dylan Roskams-Edris
MAINFRAME membership offers:
- Access to high-quality training datasets
- Participation in benchmarking challenges with experimental validation
- Collaborative research opportunities
Join a community committed to open science: aircheck.ai/mainframe
- Access to high-quality training datasets
- Participation in benchmarking challenges with experimental validation
- Collaborative research opportunities
Join a community committed to open science: aircheck.ai/mainframe
December 18, 2024 at 2:34 PM
MAINFRAME membership offers:
- Access to high-quality training datasets
- Participation in benchmarking challenges with experimental validation
- Collaborative research opportunities
Join a community committed to open science: aircheck.ai/mainframe
- Access to high-quality training datasets
- Participation in benchmarking challenges with experimental validation
- Collaborative research opportunities
Join a community committed to open science: aircheck.ai/mainframe
Reposted by Dylan Roskams-Edris
Early registration is now open for the Conscience Symposium on Open Drug Discovery in Montreal on April 7-8! To ensure accessibility for all, we're offering significantly reduced registration fees for students and Early Bird discounts until Jan 31 - don't miss out! conscience.ca/event/consci...
December 18, 2024 at 4:21 PM
Early registration is now open for the Conscience Symposium on Open Drug Discovery in Montreal on April 7-8! To ensure accessibility for all, we're offering significantly reduced registration fees for students and Early Bird discounts until Jan 31 - don't miss out! conscience.ca/event/consci...
Reposted by Dylan Roskams-Edris
You didn't think we forgot about science did you? 🧬🧪 Our 2024 year in review reflections conclude with the Open Science program at CC.
Read more about the work of Open Science and what's to come in 2025: loom.ly/LOfb8A8
Read more about the work of Open Science and what's to come in 2025: loom.ly/LOfb8A8
CC Open Science: 2024 Year in Review - Creative Commons
Science by Steve Rotman is licensed under CC BY-NC-ND 2.0 Access to science is a fundamental human right, and yet, much of that public good is inaccessible because of paywalls and limited in its reuse...
loom.ly
December 18, 2024 at 6:50 PM
You didn't think we forgot about science did you? 🧬🧪 Our 2024 year in review reflections conclude with the Open Science program at CC.
Read more about the work of Open Science and what's to come in 2025: loom.ly/LOfb8A8
Read more about the work of Open Science and what's to come in 2025: loom.ly/LOfb8A8
Waking up in the morning isn't so hard when you get to work on this mission with these people.
Millions worldwide lack treatments for diseases that threaten their lives or quality of life. We believe #OpenScience is key to tackling these challenges and that we can transform #DrugDevelopment by fostering collaboration, sharing data, and prioritizing accessibility. conscience.ca/news/drug-de...
Drug development for all: How we believe Open Science can help develop treatments for those left behind - Conscience
Health is core to our quality of life, yet millions worldwide lack treatments to diseases that threaten their lives or quality of life. For example, an estimated 400 million people worldwide live with...
conscience.ca
December 18, 2024 at 10:51 PM
Waking up in the morning isn't so hard when you get to work on this mission with these people.
Reposted by Dylan Roskams-Edris
Millions worldwide lack treatments for diseases that threaten their lives or quality of life. We believe #OpenScience is key to tackling these challenges and that we can transform #DrugDevelopment by fostering collaboration, sharing data, and prioritizing accessibility. conscience.ca/news/drug-de...
Drug development for all: How we believe Open Science can help develop treatments for those left behind - Conscience
Health is core to our quality of life, yet millions worldwide lack treatments to diseases that threaten their lives or quality of life. For example, an estimated 400 million people worldwide live with...
conscience.ca
December 18, 2024 at 8:00 PM
Millions worldwide lack treatments for diseases that threaten their lives or quality of life. We believe #OpenScience is key to tackling these challenges and that we can transform #DrugDevelopment by fostering collaboration, sharing data, and prioritizing accessibility. conscience.ca/news/drug-de...
Reposted by Dylan Roskams-Edris
Want to learn more about what we're up to at @conscience-network.bsky.social and why we do what we do? Check out our latest blog post, written by @richardgold.bsky.social (and edited by me)! I couldn't be more proud to contribute to such a great mission. #OpenScience #DrugDevelopment
Millions worldwide lack treatments for diseases that threaten their lives or quality of life. We believe #OpenScience is key to tackling these challenges and that we can transform #DrugDevelopment by fostering collaboration, sharing data, and prioritizing accessibility. conscience.ca/news/drug-de...
Drug development for all: How we believe Open Science can help develop treatments for those left behind - Conscience
Health is core to our quality of life, yet millions worldwide lack treatments to diseases that threaten their lives or quality of life. For example, an estimated 400 million people worldwide live with...
conscience.ca
December 18, 2024 at 8:06 PM
Want to learn more about what we're up to at @conscience-network.bsky.social and why we do what we do? Check out our latest blog post, written by @richardgold.bsky.social (and edited by me)! I couldn't be more proud to contribute to such a great mission. #OpenScience #DrugDevelopment
Reposted by Dylan Roskams-Edris
🥇 Inside the Best Paper from @neuripsconf.bsky.social FM4Science Workshop. Phil Fradkin of @valenceai.bsky.social presents MolPhenix - foundation model that predicts the effect of any given molecule & concentration pair on phenotypic cell assays & cell morphology. www.youtube.com/shorts/hpD4X...
https://www.youtube.com/shorts/hpD4XE6vfUY🧵
December 17, 2024 at 8:42 PM
🥇 Inside the Best Paper from @neuripsconf.bsky.social FM4Science Workshop. Phil Fradkin of @valenceai.bsky.social presents MolPhenix - foundation model that predicts the effect of any given molecule & concentration pair on phenotypic cell assays & cell morphology. www.youtube.com/shorts/hpD4X...
Thank you to @neuripsconf.bsky.social for a lovely conference.
You didn't have "taking off on a seaplane in a windstorm" in the agenda but I recommend it for next year.
Better than 5 cups of coffee.
You didn't have "taking off on a seaplane in a windstorm" in the agenda but I recommend it for next year.
Better than 5 cups of coffee.
December 14, 2024 at 6:06 PM
Thank you to @neuripsconf.bsky.social for a lovely conference.
You didn't have "taking off on a seaplane in a windstorm" in the agenda but I recommend it for next year.
Better than 5 cups of coffee.
You didn't have "taking off on a seaplane in a windstorm" in the agenda but I recommend it for next year.
Better than 5 cups of coffee.
Finished off my time at @neuripsconf.bsky.social with another stroll round some posters.
I'm not sure when we'll be simulating biology with high fidelity but it was very cool to be in the room with some of the people making that future.
Till next year.
AI-dios
I'm not sure when we'll be simulating biology with high fidelity but it was very cool to be in the room with some of the people making that future.
Till next year.
AI-dios
December 14, 2024 at 2:57 AM
Finished off my time at @neuripsconf.bsky.social with another stroll round some posters.
I'm not sure when we'll be simulating biology with high fidelity but it was very cool to be in the room with some of the people making that future.
Till next year.
AI-dios
I'm not sure when we'll be simulating biology with high fidelity but it was very cool to be in the room with some of the people making that future.
Till next year.
AI-dios
Reposted by Dylan Roskams-Edris
Special delivery from @neuripsconf.bsky.social! We just released our latest certified dataset, RxRx3-core, which includes labeled images of 735 genetic knockouts & 1,674 small-molecule perturbations. The related benchmark evaluates the zero-shot prediction of compound-gene activity. #NeurIPS
👇
👇
🛡️ New certified dataset and benchmark from
@recursionpharma.bsky.social!
Did you know that high-dimensional data like cell images (i.e. phenomics) can help us understand the relationship between compounds and genes? 🧵
Dataset: polarishub.io/datasets/rec...
Benchmark: polarishub.io/benchmarks/r...
@recursionpharma.bsky.social!
Did you know that high-dimensional data like cell images (i.e. phenomics) can help us understand the relationship between compounds and genes? 🧵
Dataset: polarishub.io/datasets/rec...
Benchmark: polarishub.io/benchmarks/r...
December 13, 2024 at 7:53 PM
Special delivery from @neuripsconf.bsky.social! We just released our latest certified dataset, RxRx3-core, which includes labeled images of 735 genetic knockouts & 1,674 small-molecule perturbations. The related benchmark evaluates the zero-shot prediction of compound-gene activity. #NeurIPS
👇
👇