Duncan Ng
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duncan-ng.bsky.social
Duncan Ng
@duncan-ng.bsky.social
730 followers 860 following 460 posts
Bioinformatician (he/him) 👨🏽‍💻 @ Wellcome Sanger Institute 🇬🇧
PhD on nasal microbiome 👃🏼 @ KU & SSI 🇩🇰

Study S. aureus carriage in nasal microbiome 🦠 | Microbial ecology & genomics 📊🧬

Enjoys 🏃🏽‍♂️📸🐕

https://linktr.ee/duncan_ng
Posts Replies Media Videos
duncan-ng.bsky.social
Maybe I’m in the wrong side of microbiome research 🍫
August 18, 2025 at 4:28 PM
Reposted by Duncan Ng
zaminiqbal.bsky.social
"We show that unrelated proteins have a universal tendency towards convergent evolution of secondary and tertiary motifs, causing an excess of high-scoring FP alignment... previous methods routinely overestimate significance by up to six orders of magnitude."
www.biorxiv.org/content/10.1...
Protein structure alignment significance is often exaggerated
Machine learning has generated millions of high-quality predicted protein structures, creating a need for computationally efficient structure search algorithms and robust estimates of statistical sign...
www.biorxiv.org
August 17, 2025 at 10:53 PM
Reposted by Duncan Ng
halllab.bsky.social
Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com!

We show that probiotics help modulate the preterm infant 👶#microbiome - to reduce ARGs, lower MDR bacteria 🦠 & increase beneficial Bifido ✨

Huge team effort!

www.nature.com/articles/s41...
August 17, 2025 at 11:54 PM
Reposted by Duncan Ng
tobiaswarnecke.bsky.social
Archaea are often surrounded by bacteria. But is there ever active conflict between the two? Can archaea kill bacteria? If so, how do they do it?

Work by @romainstrock.bsky.social shows that some archaea can kill bacteria by secreting peptidoglycan hydrolases. journals.plos.org/plosbiology/...
Archaea produce peptidoglycan hydrolases that kill bacteria
Archaea regularly interact with bacteria but reports of archaea killing bacteria are very rare. This study shows that many archaea encode peptidoglycan hydrolases, which specifically target bacterial ...
journals.plos.org
August 14, 2025 at 6:50 PM
Reposted by Duncan Ng
theriotmicrobe.bsky.social
New paper is out from our lab showing that some probiotics can accelerate and prolong the return of colonization resistance to C. difficile after antibiotics.
news.ncsu.edu/2025/07/prob...
Probiotics Can Help or Hinder Gut Recovery After Antibiotic Treatment
news.ncsu.edu
July 21, 2025 at 4:52 PM
duncan-ng.bsky.social
Got an email that my first first author paper from my PhD was accepted for publication! Cannot wait to talk about it! 🥳
a girl in a pink sweater is raising her arms in the air while a group of people are standing around her .
ALT: a girl in a pink sweater is raising her arms in the air while a group of people are standing around her .
media.tenor.com
May 28, 2025 at 7:40 AM
Reposted by Duncan Ng
mikeblazanin.bsky.social
Excited to see this new, and extensively-rewritten, version of our preprint up now! With @paulturnerlab.bsky.social we show how bacterial population dynamics (e.g. growth curves) can be used to accurately quantify bacteriophage infectivity

🦠 🧫🔬 #microbiology #VirEvol

doi.org/10.1101/2023...
Quantifying phage infectivity from characteristics of bacterial population dynamics
A frequent goal of phage biology is to quantify how well a phage kills a population of host bacteria. Unfortunately, traditional methods to quantify phage success can be time-consuming, limiting the t...
doi.org
May 27, 2025 at 10:41 PM
Reposted by Duncan Ng
onisillos.bsky.social
I never thought about wool as a possible route of infection.

www.nature.com/articles/d41...
This ancient pathogen became deadlier when humans started wearing wool
Ancient genomes reveal that a bacterial fever jumped from human-borne ticks to lice around the time wool textiles became common.
www.nature.com
May 23, 2025 at 8:39 AM
Reposted by Duncan Ng
medicrussell.bsky.social
if she doesn’t show up #Eurovision
May 17, 2025 at 9:44 PM
duncan-ng.bsky.social
Albania is… confusing. Visually great but vocally confusing
May 17, 2025 at 9:25 PM
duncan-ng.bsky.social
Love that San Marino isn’t even singing. He got someone else to do it for him
May 17, 2025 at 9:21 PM
duncan-ng.bsky.social
RIP whoever who has to clean that sand
May 17, 2025 at 9:15 PM
duncan-ng.bsky.social
Sweden understood the assignment. They gave us another banger!
May 17, 2025 at 9:09 PM
duncan-ng.bsky.social
The core strength on those dancers tho!
May 17, 2025 at 9:03 PM
duncan-ng.bsky.social
Not normally a fan of chill songs on Eurovision but Portugal is surprisingly enjoyable
May 17, 2025 at 8:58 PM
duncan-ng.bsky.social
Malta is definitely serving
May 17, 2025 at 8:55 PM
duncan-ng.bsky.social
Not sure I appreciate the camera shake
May 17, 2025 at 8:50 PM
duncan-ng.bsky.social
And we are back on track with another banger!
May 17, 2025 at 8:44 PM
duncan-ng.bsky.social
With so many bangers back to back, Greece feels very meh
May 17, 2025 at 8:42 PM
Reposted by Duncan Ng
scottygb.bsky.social
Quick #Eurovision recap:

NETHERLANDS: LA LA LA LA LA LA LA!

GERMANY: FA LA LA LA LA LA!

POLAND: AAAAAAAAAAAAAAHHHHHH!
May 17, 2025 at 8:33 PM
duncan-ng.bsky.social
Germany is bringing classic Euro trash 💖
May 17, 2025 at 8:32 PM
duncan-ng.bsky.social
Poland delivering an absolute banger from costume, fire, dancing and core workout
May 17, 2025 at 8:29 PM
duncan-ng.bsky.social
That’s one very long piano
May 17, 2025 at 8:22 PM
duncan-ng.bsky.social
Finland showing them how it’s done
May 17, 2025 at 8:19 PM
duncan-ng.bsky.social
Mix feelings about UK’s entry 🧐
May 17, 2025 at 7:57 PM