Abhimanyu
@drabhi.bsky.social
Studying Host-pathogen interaction , Epigenetics , single cell omics, tuberculosis, DNA methylation , metabolism. Staff Scientist #Uchicago; life enthusiast, an aspiring polymath; creative, Indian. Let there be light in the world .
Reposted by Abhimanyu
This case series highlights risk factors for infection by a non-tuberculous mycobacterium.
Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx
Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx
October 1, 2025 at 1:04 PM
This case series highlights risk factors for infection by a non-tuberculous mycobacterium.
Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx
Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx
Happy to share this interesting study which is now in press. We found specific Non-tuberculous mycobacterial susceptibility linked to GATA2 mutation in immunocompromised individuals @uchicagobsd.bsky.social @jci-insight.bsky.social insight.jci.org/articles/vie...
JCI Insight -
GATA2 mutation is associated with immune dysfunction and increased Mycobacterium haemophilum susceptibility in immunocompromised individuals
insight.jci.org
August 10, 2025 at 3:30 PM
Happy to share this interesting study which is now in press. We found specific Non-tuberculous mycobacterial susceptibility linked to GATA2 mutation in immunocompromised individuals @uchicagobsd.bsky.social @jci-insight.bsky.social insight.jci.org/articles/vie...
Reposted by Abhimanyu
Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.
Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery
MS-based immunopeptidomics can facilitate vaccine antigen discovery, but self-MHC peptides greatly outnumber pathogen-derived MHC peptides, presenting a ch
doi.org
July 21, 2025 at 2:19 PM
Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.
In the midst of everything take a break , protect your sanity and refuel to keep at it . #easter #timeoff #vitaminsea
April 20, 2025 at 11:29 PM
In the midst of everything take a break , protect your sanity and refuel to keep at it . #easter #timeoff #vitaminsea
Happy to be part of this cool paper ! BCG trial for prevention of COVID-19 in healthcare workers, interrupted with speedy arrival of the COVID vaccines. The vaccinated cohort 12-months later show improved COVID-19 immunity, key player DNA methylation! #BCG #DNAmethylation @globaltb.bsky.social
January 21, 2025 at 8:33 AM
Happy to be part of this cool paper ! BCG trial for prevention of COVID-19 in healthcare workers, interrupted with speedy arrival of the COVID vaccines. The vaccinated cohort 12-months later show improved COVID-19 immunity, key player DNA methylation! #BCG #DNAmethylation @globaltb.bsky.social
Happy 2025! Ready to get back to the science after a reset trip to beautiful #sanfrancisco #yosemite
January 2, 2025 at 1:05 PM
Happy 2025! Ready to get back to the science after a reset trip to beautiful #sanfrancisco #yosemite
A good day spent in listening to talks from four neighboring labs which are incidentally on the same floor . From #proteinengineering , #phageengineering , hightroughput #microfluidics and traditional conditional knockout #micemodels . #uchicago . Science is in good hands !
November 15, 2024 at 1:36 AM
A good day spent in listening to talks from four neighboring labs which are incidentally on the same floor . From #proteinengineering , #phageengineering , hightroughput #microfluidics and traditional conditional knockout #micemodels . #uchicago . Science is in good hands !
Reposted by Abhimanyu
“Money reigns as perhaps the biggest obstacle” 🧪🩺
TB reclaims title of deadliest infectious disease. That's an 'outrage' says WHO
DIslodged by COVID early in the pandemic, tuberculosis is once again the infectious disease that takes the most lives each year. And the number of cases set a new record. What's going on?
www.npr.org
November 8, 2024 at 10:28 PM
“Money reigns as perhaps the biggest obstacle” 🧪🩺
Reposted by Abhimanyu
I made a Starter Pack for the Myco & TB community.
Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost!
go.bsky.app/3nwpcVV
Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost!
go.bsky.app/3nwpcVV
November 11, 2024 at 7:54 AM
I made a Starter Pack for the Myco & TB community.
Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost!
go.bsky.app/3nwpcVV
Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost!
go.bsky.app/3nwpcVV