Doryen Bubeck
@doryenbubeck.bsky.social
Professor of Structural Immunology, Director of Research Department of Life Sciences, Imperial College London
This was me with my mom going for an @EMBO young investigator award interview 2 weeks after my son was born. Thank goodness for moms and a quick turn around at the passport office 😆
October 13, 2025 at 8:46 PM
This was me with my mom going for an @EMBO young investigator award interview 2 weeks after my son was born. Thank goodness for moms and a quick turn around at the passport office 😆
Thanks @ccpem.bsky.social for an excellent workshop today showing @imperiallifesci.bsky.social what we can do with #doppio on our new computing cluster funded by @ukri.org
September 30, 2025 at 8:59 PM
Thanks @ccpem.bsky.social for an excellent workshop today showing @imperiallifesci.bsky.social what we can do with #doppio on our new computing cluster funded by @ukri.org
Reposted by Doryen Bubeck
In our latest preprint on bioRxiv, we present the in situ structure of
the human gap junction at 14 Å resolution using cryo-ET.
The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.
the human gap junction at 14 Å resolution using cryo-ET.
The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.
July 8, 2025 at 5:33 AM
In our latest preprint on bioRxiv, we present the in situ structure of
the human gap junction at 14 Å resolution using cryo-ET.
The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.
the human gap junction at 14 Å resolution using cryo-ET.
The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.
Reposted by Doryen Bubeck
Our latest story describes the amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind inhibitory KIR receptors and suppress immune cell function while humans have activating KIR receptors to bind these RIFINs to kill parasites!
June 13, 2025 at 3:52 PM
Our latest story describes the amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind inhibitory KIR receptors and suppress immune cell function while humans have activating KIR receptors to bind these RIFINs to kill parasites!
Reposted by Doryen Bubeck
Thank you everyone who sponsored the @doryenbubeck.bsky.social Bubeck lab to run the CRUK Pretty Muddy Race for Life. The team raised over £1200!
#OurImperial
fundraise.cancerresearchuk.org/page/doryens...
#OurImperial
fundraise.cancerresearchuk.org/page/doryens...
June 8, 2025 at 6:11 PM
Thank you everyone who sponsored the @doryenbubeck.bsky.social Bubeck lab to run the CRUK Pretty Muddy Race for Life. The team raised over £1200!
#OurImperial
fundraise.cancerresearchuk.org/page/doryens...
#OurImperial
fundraise.cancerresearchuk.org/page/doryens...
Reposted by Doryen Bubeck
Join us for our next #ConvergingOnCancer seminar where we'll explore these topics with:
➡️Prof @doryenbubeck.bsky.social (@imperialsci.bsky.social)
➡️Dr @claudioalfieri.bsky.social (@icr.ac.uk )
📅 Thursday 5th June, 3-4pm
🖱️ For more information and how to register: bit.ly/3Z80SqS
➡️Prof @doryenbubeck.bsky.social (@imperialsci.bsky.social)
➡️Dr @claudioalfieri.bsky.social (@icr.ac.uk )
📅 Thursday 5th June, 3-4pm
🖱️ For more information and how to register: bit.ly/3Z80SqS
June 2, 2025 at 9:02 AM
Join us for our next #ConvergingOnCancer seminar where we'll explore these topics with:
➡️Prof @doryenbubeck.bsky.social (@imperialsci.bsky.social)
➡️Dr @claudioalfieri.bsky.social (@icr.ac.uk )
📅 Thursday 5th June, 3-4pm
🖱️ For more information and how to register: bit.ly/3Z80SqS
➡️Prof @doryenbubeck.bsky.social (@imperialsci.bsky.social)
➡️Dr @claudioalfieri.bsky.social (@icr.ac.uk )
📅 Thursday 5th June, 3-4pm
🖱️ For more information and how to register: bit.ly/3Z80SqS
Reposted by Doryen Bubeck
⏰ Deadline approaching for postdoc position in my lab, Dunn School, University of Oxford.
We work on how the cell's antenna receives and transmits essential signals through motor protein driven transport.
❄️ Cryo-EM/ET, smTIRF, cell biology methods 🧪🔬
30/5/25 ➡️ tinyurl.com/KToropovaPDRA
We work on how the cell's antenna receives and transmits essential signals through motor protein driven transport.
❄️ Cryo-EM/ET, smTIRF, cell biology methods 🧪🔬
30/5/25 ➡️ tinyurl.com/KToropovaPDRA
May 28, 2025 at 3:00 PM
⏰ Deadline approaching for postdoc position in my lab, Dunn School, University of Oxford.
We work on how the cell's antenna receives and transmits essential signals through motor protein driven transport.
❄️ Cryo-EM/ET, smTIRF, cell biology methods 🧪🔬
30/5/25 ➡️ tinyurl.com/KToropovaPDRA
We work on how the cell's antenna receives and transmits essential signals through motor protein driven transport.
❄️ Cryo-EM/ET, smTIRF, cell biology methods 🧪🔬
30/5/25 ➡️ tinyurl.com/KToropovaPDRA
Reposted by Doryen Bubeck
Still time to sponsor @doryenbubeck.bsky.social who ran the Pretty Muddy Race for Life for Cancer Research UK this weekend! Congrats Doryen!
fundraise.cancerresearchuk.org/page/doryens...
fundraise.cancerresearchuk.org/page/doryens...
Doryen's Race for Life
I haven't met a single person whose life has not been touch by cancer. The current statistic is that 1 in 2 people will be diagnosed with cancer in their lifetime. As a scientist I know the significan...
fundraise.cancerresearchuk.org
May 24, 2025 at 9:47 PM
Still time to sponsor @doryenbubeck.bsky.social who ran the Pretty Muddy Race for Life for Cancer Research UK this weekend! Congrats Doryen!
fundraise.cancerresearchuk.org/page/doryens...
fundraise.cancerresearchuk.org/page/doryens...
Reposted by Doryen Bubeck
Exciting progress in drug discovery - a cross-disciplinary team including @doryenbubeck.bsky.social, Tate and Kawamura researchers have developed the first macrocyclic peptide inhibitors for CD59 — a tricky cell-surface receptor often hijacked by bacteria.
www.imperial.ac.uk/news/263433/...
www.imperial.ac.uk/news/263433/...
Macrocyclic peptide inhibitors for CD59 receptor | Imperial News | Imperial College London
A collaboration between the Tate, Bubeck and Kawamura groups has developed the first macrocyclic peptide inhibitors for cell-surface receptor CD59
www.imperial.ac.uk
May 15, 2025 at 5:04 PM
Exciting progress in drug discovery - a cross-disciplinary team including @doryenbubeck.bsky.social, Tate and Kawamura researchers have developed the first macrocyclic peptide inhibitors for CD59 — a tricky cell-surface receptor often hijacked by bacteria.
www.imperial.ac.uk/news/263433/...
www.imperial.ac.uk/news/263433/...
Reposted by Doryen Bubeck
We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.
Excellent opportunity available for a motivated #postdoc to join @kellythd-nguyen.bsky.social’s group investigating the roles of histones in regulating telomerase using a multi-disciplinary approach.
More details: www.nature.com/naturecareer...
Apply by 04 MAY
#PostdocJobs #ScienceJobs
More details: www.nature.com/naturecareer...
Apply by 04 MAY
#PostdocJobs #ScienceJobs
April 16, 2025 at 5:25 PM
We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.
Great day collecting cryo SIM data @diamondlightsource.bsky.social
April 14, 2025 at 5:28 PM
Great day collecting cryo SIM data @diamondlightsource.bsky.social
Honored to have been chosen for this year’s GlaxoSmithKline Award from @biochemsoc.bsky.social. A big thank you to lab members past and present @imperialsci.bsky.social and @erc.europa.eu @cruk-si.bsky.social @wellcometrust.bsky.social for supporting our work.
The 2026 GlaxoSmithKline Award goes to Doryen Bubeck! Internationally recognised, @doryenbubeck.bsky.social's pioneering research in structural immunology has laid a foundation for future treatments targeting immune-mediated diseases and infectious pathogens.
April 8, 2025 at 12:43 PM
Honored to have been chosen for this year’s GlaxoSmithKline Award from @biochemsoc.bsky.social. A big thank you to lab members past and present @imperialsci.bsky.social and @erc.europa.eu @cruk-si.bsky.social @wellcometrust.bsky.social for supporting our work.
Reposted by Doryen Bubeck
Did you miss the @doryenbubeck.bsky.social inaugural lecture last week or just fancy re-watching?! 😀
Join Doryen in the fascinating world of proteins, the "tiny machines" that drive cellular functions, using cryo electron microscopy.
www.youtube.com/live/H14PeFt...
#OurImperial
Join Doryen in the fascinating world of proteins, the "tiny machines" that drive cellular functions, using cryo electron microscopy.
www.youtube.com/live/H14PeFt...
#OurImperial
March 19, 2025 at 2:43 PM
Did you miss the @doryenbubeck.bsky.social inaugural lecture last week or just fancy re-watching?! 😀
Join Doryen in the fascinating world of proteins, the "tiny machines" that drive cellular functions, using cryo electron microscopy.
www.youtube.com/live/H14PeFt...
#OurImperial
Join Doryen in the fascinating world of proteins, the "tiny machines" that drive cellular functions, using cryo electron microscopy.
www.youtube.com/live/H14PeFt...
#OurImperial
Reposted by Doryen Bubeck
We're excited that Facilities Manager Sam Horrell has made it to the London Final of FameLab, a science outreach competition with 3 minutes to explain a scientific topic in an engaging way. The final is on 2 April and is free - please come & support Sam!
www.eventbrite.co.uk/e/london-fam...
www.eventbrite.co.uk/e/london-fam...
London FameLab Final
Experience the excitement of the London FameLab Final! Enjoy engaging science talks as contestants compete for a place in the UK Final.
www.eventbrite.co.uk
March 17, 2025 at 6:58 PM
We're excited that Facilities Manager Sam Horrell has made it to the London Final of FameLab, a science outreach competition with 3 minutes to explain a scientific topic in an engaging way. The final is on 2 April and is free - please come & support Sam!
www.eventbrite.co.uk/e/london-fam...
www.eventbrite.co.uk/e/london-fam...
Reposted by Doryen Bubeck
Sad news about Karen Davies' passing.
Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution
scholar.google.com/citations?hl...
Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution
scholar.google.com/citations?hl...
Karen Davies
Formerly of Electron Bio-Imaging Centre, Diamond Light Source, United Kingdom - Cited by 2,887 - cryo-EM - tomography - method development - bioenergetics
scholar.google.com
March 12, 2025 at 8:33 PM
Sad news about Karen Davies' passing.
Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution
scholar.google.com/citations?hl...
Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution
scholar.google.com/citations?hl...
Reposted by Doryen Bubeck
Great live demonstration of how election microscopy works, and the signal to noise challenge in atomic imaging, at @doryenbubeck.bsky.social's inaugural lecture #imperialinaugural
March 12, 2025 at 5:51 PM
Great live demonstration of how election microscopy works, and the signal to noise challenge in atomic imaging, at @doryenbubeck.bsky.social's inaugural lecture #imperialinaugural
Reposted by Doryen Bubeck
Amazing inaugural lecture tonight from @doryenbubeck.bsky.social
Proteins scatter electrons, but the images are noisy...check out how an electron microscope works as showcased by our Head of Department @dandavis101.bsky.social 😄😃🔬
Proteins scatter electrons, but the images are noisy...check out how an electron microscope works as showcased by our Head of Department @dandavis101.bsky.social 😄😃🔬
March 12, 2025 at 8:26 PM
Amazing inaugural lecture tonight from @doryenbubeck.bsky.social
Proteins scatter electrons, but the images are noisy...check out how an electron microscope works as showcased by our Head of Department @dandavis101.bsky.social 😄😃🔬
Proteins scatter electrons, but the images are noisy...check out how an electron microscope works as showcased by our Head of Department @dandavis101.bsky.social 😄😃🔬
Reposted by Doryen Bubeck
Thanks so much @doryenbubeck.bsky.social for an amazing inaugural lecture tonight, 'Big Questions, Tiny Machines' nothing short of inspiring for our packed audience! 👩🏫
#OurImperial
Did you miss it?! No worries if so, as you can check out the recording below:
www.youtube.com/live/H14PeFt...
#OurImperial
Did you miss it?! No worries if so, as you can check out the recording below:
www.youtube.com/live/H14PeFt...
Big questions, tiny machines
YouTube video by Imperial College London
www.youtube.com
March 12, 2025 at 8:29 PM
Thanks so much @doryenbubeck.bsky.social for an amazing inaugural lecture tonight, 'Big Questions, Tiny Machines' nothing short of inspiring for our packed audience! 👩🏫
#OurImperial
Did you miss it?! No worries if so, as you can check out the recording below:
www.youtube.com/live/H14PeFt...
#OurImperial
Did you miss it?! No worries if so, as you can check out the recording below:
www.youtube.com/live/H14PeFt...
Reposted by Doryen Bubeck
A highlight of Professor @doryenbubeck.bsky.social‘s inaugural lecture tonight was @dandavis101.bsky.social being pounded with electrons…
March 12, 2025 at 9:00 PM
A highlight of Professor @doryenbubeck.bsky.social‘s inaugural lecture tonight was @dandavis101.bsky.social being pounded with electrons…
Reposted by Doryen Bubeck
🎉 And that’s a wrap!
The Wellcome-MRC Cryo-EM in Structural Biology 2025 course in Leeds was a fantastic week of learning, hands-on training, and great discussions.
Huge thanks to our amazing instructors, speakers & enthusiastic participants for making it such a success! #CryoEM
The Wellcome-MRC Cryo-EM in Structural Biology 2025 course in Leeds was a fantastic week of learning, hands-on training, and great discussions.
Huge thanks to our amazing instructors, speakers & enthusiastic participants for making it such a success! #CryoEM
March 11, 2025 at 3:59 PM
🎉 And that’s a wrap!
The Wellcome-MRC Cryo-EM in Structural Biology 2025 course in Leeds was a fantastic week of learning, hands-on training, and great discussions.
Huge thanks to our amazing instructors, speakers & enthusiastic participants for making it such a success! #CryoEM
The Wellcome-MRC Cryo-EM in Structural Biology 2025 course in Leeds was a fantastic week of learning, hands-on training, and great discussions.
Huge thanks to our amazing instructors, speakers & enthusiastic participants for making it such a success! #CryoEM
Reposted by Doryen Bubeck
Don't forget to come to Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"! Open to all!!
📅 Wed, 12 March 2025
Understanding how pathogen proteins interact with human defence systems means we can develop new ways to prevent disease.
@doryenbubeck.bsky.social
#OurImperial
📅 Wed, 12 March 2025
Understanding how pathogen proteins interact with human defence systems means we can develop new ways to prevent disease.
@doryenbubeck.bsky.social
#OurImperial
February 17, 2025 at 1:01 PM
Don't forget to come to Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"! Open to all!!
📅 Wed, 12 March 2025
Understanding how pathogen proteins interact with human defence systems means we can develop new ways to prevent disease.
@doryenbubeck.bsky.social
#OurImperial
📅 Wed, 12 March 2025
Understanding how pathogen proteins interact with human defence systems means we can develop new ways to prevent disease.
@doryenbubeck.bsky.social
#OurImperial
Reposted by Doryen Bubeck
Really looking forward to this. Come along if you can!
🔬 Join us for Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
February 4, 2025 at 8:55 AM
Really looking forward to this. Come along if you can!
Reposted by Doryen Bubeck
🔬 Join us for Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
February 3, 2025 at 3:57 PM
🔬 Join us for Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
@doryenbubeck.bsky.social @imperiallifesci.bsky.social
📅 Wed, 12 March 2025
Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe
Reposted by Doryen Bubeck
1) We have an exciting job opportunity in correlative bioimaging at B24 at @diamondlightsource.bsky.social applying cryo soft x-ray microscopy (cryoSXT) and super-resolution 3D structured illumination fluorescence Microscopy (CryoSIM)
Beamline Scientist - 3D Correlative cryo-Bioimaging (11526)
tinyurl.com
January 29, 2025 at 3:47 PM
1) We have an exciting job opportunity in correlative bioimaging at B24 at @diamondlightsource.bsky.social applying cryo soft x-ray microscopy (cryoSXT) and super-resolution 3D structured illumination fluorescence Microscopy (CryoSIM)