David Sas
@davidsas.bsky.social
Pediatric nephrology, genetic kidney stone diseases, trail running, Nordic skiing, photography, smoking just about any kind of animal, history, sports, education. Views are my own.
I'm super proud of this work detailing the results of genetic testing in hundreds of kidney stone formers. We identified genetic causes for stones in 34% of those tested (47% if < 16 y.o.). So thankful for such great collaborators & patients! journals.lww.com/cjasn/fullte... #nephrology #mayoclinic
journals.lww.com
October 27, 2025 at 9:46 PM
I'm super proud of this work detailing the results of genetic testing in hundreds of kidney stone formers. We identified genetic causes for stones in 34% of those tested (47% if < 16 y.o.). So thankful for such great collaborators & patients! journals.lww.com/cjasn/fullte... #nephrology #mayoclinic
I love it when I realize I hit send on an email in which I type-o'd "my" to "me" and I sound Cockney, e.g. "Let me discuss it with me team."
a man wearing a hat is holding a trumpet and adjusting his hat .
ALT: a man wearing a hat is holding a trumpet and adjusting his hat .
media.tenor.com
July 31, 2025 at 1:37 PM
I love it when I realize I hit send on an email in which I type-o'd "my" to "me" and I sound Cockney, e.g. "Let me discuss it with me team."
Hot take: Academics are just an isoform of social media influencer. Publications are clicks and citations are likes. H-index = clout.
May 22, 2025 at 1:05 PM
Hot take: Academics are just an isoform of social media influencer. Publications are clicks and citations are likes. H-index = clout.
I have a pediatric patient who refers to her serum phosphorus as "serum preposterous" so that's what I'm calling it from now on.
a cartoon of daffy duck with the words " this is preposterous " below him
ALT: a cartoon of daffy duck with the words " this is preposterous " below him
media.tenor.com
May 1, 2025 at 7:07 PM
I have a pediatric patient who refers to her serum phosphorus as "serum preposterous" so that's what I'm calling it from now on.
Happy Match Day, and thanks to @jbcarmody for continuing to do this thorough and important analysis!
Today is Match Day.
So you know what that means.
It’s time to break things down, Winners & Losers™️ style.
Match Day 2025: Winners & Losers Edition
youtu.be/ckbO6ykf2f8
So you know what that means.
It’s time to break things down, Winners & Losers™️ style.
Match Day 2025: Winners & Losers Edition
youtu.be/ckbO6ykf2f8
Match Day 2025: Winners & Losers Edition
YouTube video by Sheriff of Sodium
youtu.be
March 22, 2025 at 1:14 AM
Happy Match Day, and thanks to @jbcarmody for continuing to do this thorough and important analysis!
You know why I love a hepatectomy?
It always de-livers!
I just made that up and am amused with myself. But also appropriately disappointed.
It always de-livers!
I just made that up and am amused with myself. But also appropriately disappointed.
March 20, 2025 at 1:03 AM
You know why I love a hepatectomy?
It always de-livers!
I just made that up and am amused with myself. But also appropriately disappointed.
It always de-livers!
I just made that up and am amused with myself. But also appropriately disappointed.
Reposted by David Sas
From JAMA Cardiology:
South African regulations limiting sodium in processed foods were associated with reductions in sodium consumption and blood pressure among rural adults aged 40 years or older.
ja.ma/4hMWyUW
#CardioSky
South African regulations limiting sodium in processed foods were associated with reductions in sodium consumption and blood pressure among rural adults aged 40 years or older.
ja.ma/4hMWyUW
#CardioSky
February 5, 2025 at 7:29 PM
From JAMA Cardiology:
South African regulations limiting sodium in processed foods were associated with reductions in sodium consumption and blood pressure among rural adults aged 40 years or older.
ja.ma/4hMWyUW
#CardioSky
South African regulations limiting sodium in processed foods were associated with reductions in sodium consumption and blood pressure among rural adults aged 40 years or older.
ja.ma/4hMWyUW
#CardioSky
Pt (w/ permission) showing # of nights @ Ronald McDonald House paid for so far at this amazing fund raiser co-chaired by my beautiful wife, Samantha. Looking for a worthwhile charity? #RonaldMcDonaldHouse provides wonderful services for peds pts & is a valuable partner with Mayo Clinic Children's.
February 2, 2025 at 2:47 AM
Pt (w/ permission) showing # of nights @ Ronald McDonald House paid for so far at this amazing fund raiser co-chaired by my beautiful wife, Samantha. Looking for a worthwhile charity? #RonaldMcDonaldHouse provides wonderful services for peds pts & is a valuable partner with Mayo Clinic Children's.
Update on ALA treatment for cystinuria reveals we have a long way to go before nephrologists will be satisfied with evidence that it is effective and safe. Also, no one has supplied a viable mechanism of action. #rock2015
January 31, 2025 at 9:09 PM
Update on ALA treatment for cystinuria reveals we have a long way to go before nephrologists will be satisfied with evidence that it is effective and safe. Also, no one has supplied a viable mechanism of action. #rock2015
"Let's take a walk through the nephron and focus on calcium" is how kidney stone nephrologists say, "I love you."
@R.O.C.K. Society Annual Meeting 2025
@R.O.C.K. Society Annual Meeting 2025
January 31, 2025 at 6:39 PM
"Let's take a walk through the nephron and focus on calcium" is how kidney stone nephrologists say, "I love you."
@R.O.C.K. Society Annual Meeting 2025
@R.O.C.K. Society Annual Meeting 2025
I love this thread because it illustrates the niche expertise hidden all around us.
BlueSky Historians - what’s the most ahistorical thing you have ever seen in a film/TV show which was meant to be historical?
(For me it has to be the use of Zadok the Priest playing during the Papal coronation of Rodrigo Borgia - Alexander VI - in The Borgias. 235 years before it was composed.)
(For me it has to be the use of Zadok the Priest playing during the Papal coronation of Rodrigo Borgia - Alexander VI - in The Borgias. 235 years before it was composed.)
January 15, 2025 at 3:03 AM
I love this thread because it illustrates the niche expertise hidden all around us.
Eloquent opinion piece:
Great piece by Paul Offit
"When Mr. Kennedy says he wants vaccines to be better studied, what he really seems to be saying is he wants studies that confirm his fixed, immutable, science-resistant beliefs. That’s not skepticism."🧪⚕️
"When Mr. Kennedy says he wants vaccines to be better studied, what he really seems to be saying is he wants studies that confirm his fixed, immutable, science-resistant beliefs. That’s not skepticism."🧪⚕️
Opinion | RFK Jr. Is a Vaccine Cynic, Not Skeptic. (Gift Article)
My job is to ask tough questions of vaccine makers. That’s not what he is doing.
www.nytimes.com
January 13, 2025 at 6:36 PM
Eloquent opinion piece:
Great article!
Thrilled to have my essay on the serendipitous history of Botox and how it relates to the doctor-patient relationship published by @medpagetoday.bsky.social today!
www.medpagetoday.com/opinion/seco...
www.medpagetoday.com/opinion/seco...
January 11, 2025 at 11:43 PM
Great article!
Reposted by David Sas
Kids getting kidney stones! @davidsas.bsky.social and Greg Tasian ("it's NOT just white, middle-aged men") @nyunephro.bsky.social www.msn.com/en-gb/health...
MSN
www.msn.com
January 6, 2025 at 1:38 AM
Kids getting kidney stones! @davidsas.bsky.social and Greg Tasian ("it's NOT just white, middle-aged men") @nyunephro.bsky.social www.msn.com/en-gb/health...
The best thing about the end of the year is seeing all the regularly-scheduled meetings get canceled and drop off the calendar.
December 19, 2024 at 8:45 PM
The best thing about the end of the year is seeing all the regularly-scheduled meetings get canceled and drop off the calendar.
Reposted by David Sas
December 12, 2024 at 11:34 AM
Reposted by David Sas
1/n sharing a case: Young adult comes in 4 elective ENT procedure. Receives several doses of ketotolac for 3-4 days + empiric vancomycin. Then, labs are checked: Cr 4.0, up from 1.0. UA: neg blood/protein/cells. High suspicion 4 IV NSAID / IV Vanco hemodynamic/tubular insult. Non-oliguric, lytes OK
December 4, 2024 at 11:22 PM
1/n sharing a case: Young adult comes in 4 elective ENT procedure. Receives several doses of ketotolac for 3-4 days + empiric vancomycin. Then, labs are checked: Cr 4.0, up from 1.0. UA: neg blood/protein/cells. High suspicion 4 IV NSAID / IV Vanco hemodynamic/tubular insult. Non-oliguric, lytes OK
Reposted by David Sas
Most hospitals have dropped masking & #SARSCoV2 testing requirements. But after 10 Boston hospitals ended both precautions a surge in hospital-onset viral infections ensued. Just resuming masks—for healthcare workers only—lowered rates of respiratory infections by 33% jamanetwork.com/journals/jam...
Testing and Masking Policies and Hospital-Onset Respiratory Viral Infections
This cohort study examines the ratio between hospital- and community-onset respiratory viral infections at different levels of testing and masking from 2020 to 2024.
jamanetwork.com
December 3, 2024 at 1:03 PM
Most hospitals have dropped masking & #SARSCoV2 testing requirements. But after 10 Boston hospitals ended both precautions a surge in hospital-onset viral infections ensued. Just resuming masks—for healthcare workers only—lowered rates of respiratory infections by 33% jamanetwork.com/journals/jam...
A perfect 0.01 act play. >chef's kiss<
*calling hematology from the PICU*
Me: hey I have a 2 year old here with a hemoglobin of 3
Heme: type and cross, send x, y, z labs but it's gonna be milk intake
Heme: what's the child's diet
Me: they only drink milk
- Fin
Me: hey I have a 2 year old here with a hemoglobin of 3
Heme: type and cross, send x, y, z labs but it's gonna be milk intake
Heme: what's the child's diet
Me: they only drink milk
- Fin
Optimist: The cup is half full
Pessimist: The cup is half empty
Pediatric hematologist: Take that cup of milk away from the toddler, he already drank 60 ounces today and his hemoglobin is 2
Pessimist: The cup is half empty
Pediatric hematologist: Take that cup of milk away from the toddler, he already drank 60 ounces today and his hemoglobin is 2
November 24, 2024 at 2:48 PM
A perfect 0.01 act play. >chef's kiss<
I've always assumed that people who drink ethylene glycol do it because they've internally asked themselves, "I wonder what it's like to have primary hyperoxaluria, types 1, 2, or 3?"
Ethylene glycol intoxication presents w/ anion gap metabolic acidosis & acute oxalate tubulopathy. Detection of urinary calcium oxalate monohydrate crystals helps in diagnosis [not classic dumbbell nor envelope shaped (dihydrate) but rather “cigar” shaped]. Slide courtesy of @jrseltzer.bsky.social
November 23, 2024 at 2:33 AM
I've always assumed that people who drink ethylene glycol do it because they've internally asked themselves, "I wonder what it's like to have primary hyperoxaluria, types 1, 2, or 3?"
I wish there was an award for who most diligently updates Family History and Social History in Epic.
November 20, 2024 at 10:00 PM
I wish there was an award for who most diligently updates Family History and Social History in Epic.
Fun fact: cystinuria was the first of the genetic kidney stone diseases to be characterized. Garrod presented his findings at the 1908 Croonian Lectures in London. Primary hyperoxaluria was the next to be described, and that was in 1925 by Lepoutre.
Cystine crystals (bright field, x400).
Their presence in #urinarysediment is pathognomonic for #cystinuria, the most common kidney stone disease with Mendelian genetics.
While perfectly specific, the sensitivity of cystine crystalluria is quite low.
#nephsky #skyneph
Their presence in #urinarysediment is pathognomonic for #cystinuria, the most common kidney stone disease with Mendelian genetics.
While perfectly specific, the sensitivity of cystine crystalluria is quite low.
#nephsky #skyneph
November 19, 2024 at 11:10 PM
Fun fact: cystinuria was the first of the genetic kidney stone diseases to be characterized. Garrod presented his findings at the 1908 Croonian Lectures in London. Primary hyperoxaluria was the next to be described, and that was in 1925 by Lepoutre.
Says a lot about Tyson that my son is going to watch a Tyson fight with his friends just the way I did in high school.
November 16, 2024 at 1:42 AM
Says a lot about Tyson that my son is going to watch a Tyson fight with his friends just the way I did in high school.
I love a deep dive into our college admissions processes.
Truly excellent work from The Harvard Crimson here:
“Of all schools that have sent students to Harvard, one in 11 students has come from just 21 high schools across the United States.”
interactives.thecrimson.com/2024/news/fe...
“Of all schools that have sent students to Harvard, one in 11 students has come from just 21 high schools across the United States.”
interactives.thecrimson.com/2024/news/fe...
Most Schools Dream of Sending Students to Harvard. These 21 Expect To.
interactives.thecrimson.com
November 15, 2024 at 6:27 PM
I love a deep dive into our college admissions processes.