David Romero
@davidromeroc60.bsky.social
Investigador en el Centro de Ciencias Genómicas-UNAM, amante de la lectura, disfruto paseos por las montañas y la buena cocina
Scientist at the Center for Genomic Sciences at Cuernavaca, Mexico, proud grandfather, avid reader and hiker, enjoy cooking
Scientist at the Center for Genomic Sciences at Cuernavaca, Mexico, proud grandfather, avid reader and hiker, enjoy cooking
Reposted by David Romero
"Creemos nuestro deber realizar diversas cosas: educar a los hijos, acumular un patrimonio, escribir un libro, descubrir una ley científica, pero sólo hay una cosa que hacer: modelar nuestra vida, hacer de ella algo íntegro, racional, bueno".
#tolstoi
#tolstoi
September 4, 2025 at 5:42 PM
"Creemos nuestro deber realizar diversas cosas: educar a los hijos, acumular un patrimonio, escribir un libro, descubrir una ley científica, pero sólo hay una cosa que hacer: modelar nuestra vida, hacer de ella algo íntegro, racional, bueno".
#tolstoi
#tolstoi
Reposted by David Romero
With great joy—and a touch of nervousness—I’m thrilled to share that my first academic monograph will be published by @mitpress.bsky.social in May 2026! It examines the organism–environment relationship in biology from an integrated #HPS perspective: mitpress.mit.edu/978026205282... #evosky #philsky
The Organism-Environment Pairing
In this first systematic book-length examination of the organism-environment relationship in the life sciences, Alejandro Fábregas-Tejeda addresses a crucia...
mitpress.mit.edu
August 21, 2025 at 2:20 PM
With great joy—and a touch of nervousness—I’m thrilled to share that my first academic monograph will be published by @mitpress.bsky.social in May 2026! It examines the organism–environment relationship in biology from an integrated #HPS perspective: mitpress.mit.edu/978026205282... #evosky #philsky
Reposted by David Romero
"Lo que mucha gente llama amar consiste en elegir a una mujer y casarse con ella. La eligen, te lo juro, los he visto. Como si se pudiese elegir en el amor, como si no fuera un rayo que te parte los huesos y te deja estaqueado en la mitad del patio".
Rayuela, Julio Cortazar.
Rayuela, Julio Cortazar.
August 18, 2025 at 12:57 PM
"Lo que mucha gente llama amar consiste en elegir a una mujer y casarse con ella. La eligen, te lo juro, los he visto. Como si se pudiese elegir en el amor, como si no fuera un rayo que te parte los huesos y te deja estaqueado en la mitad del patio".
Rayuela, Julio Cortazar.
Rayuela, Julio Cortazar.
Reposted by David Romero
August 15, 2025 at 8:08 PM
Reposted by David Romero
Music to my ears. This is brilliant. Either 90% of us can claim to be better musicians than Beethoven or… maybe just maybe polygenic scores aren’t perfect?
If someone you know buys into claims about "genetic optimization" of embryos using polygenic scores of cognition, just send them our 2024 paper on Beethoven & musicality. We wrote it to help communicate limits of individual-level genetic predictions & complexity of links between DNA & behaviour. 🧪👇
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven
with population-based datasets used to quantify musical achievement.
www.cell.com
August 15, 2025 at 4:14 AM
Music to my ears. This is brilliant. Either 90% of us can claim to be better musicians than Beethoven or… maybe just maybe polygenic scores aren’t perfect?
A wonderful, thought-provoking review
www.nature.com/articles/s41...
www.nature.com/articles/s41...
How and when organisms edit their own genomes - Nature Genetics
This Review describes the changes that some organisms make to their own DNA sequences, linking many to common genetic mechanisms built around canonical DNA repair and to a set of functional circumstan...
www.nature.com
August 12, 2025 at 9:51 PM
A wonderful, thought-provoking review
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by David Romero
A red algal polysaccharide influences the multicellular development of the choanoflagellate Salpingoeca rosetta
in @currentbiology.bsky.social
www.cell.com/current-biol...
in @currentbiology.bsky.social
www.cell.com/current-biol...
A red algal polysaccharide influences the multicellular development of the choanoflagellate Salpingoeca rosetta
Perotti et al. find that polysaccharides from algae promote multicellular development
in the choanoflagellate S. rosetta. Because algal polysaccharides are abundant in
the aquatic environments where S...
www.cell.com
July 22, 2025 at 9:29 AM
Reposted by David Romero
Did you know that some microbes can simultaneously respire aerobically and anaerobically, even in fully oxic environments?
This article elaborates on a flexible strategy that reshapes traditional understanding of microbial metabolism: asm.org/articles/202...
This article elaborates on a flexible strategy that reshapes traditional understanding of microbial metabolism: asm.org/articles/202...
Flexible Microbial Respiration: Beyond the Oxygen Paradigm | ASM.org
Some microbes can simultaneously respire aerobically and anaerobically, a flexible strategy that reshapes our understanding of microbial metabolism.
asm.org
July 22, 2025 at 1:56 PM
Did you know that some microbes can simultaneously respire aerobically and anaerobically, even in fully oxic environments?
This article elaborates on a flexible strategy that reshapes traditional understanding of microbial metabolism: asm.org/articles/202...
This article elaborates on a flexible strategy that reshapes traditional understanding of microbial metabolism: asm.org/articles/202...
Reposted by David Romero
Thrilled to share this work! I am honored to learn from @mlbendall.bsky.social and so grateful for his guidance and mentorship.
Stellarscope is just the beginning!
There is so much to learn about TEs and now we can all explore the uncharted territory of single cell retro-genomics 🧬🔭
Stellarscope is just the beginning!
There is so much to learn about TEs and now we can all explore the uncharted territory of single cell retro-genomics 🧬🔭
🧵1/ Introducing Stellarscope: an EM-based tool for quantifying locus-specific transposable element expression in single cells.
A single-cell transposable element atlas of human cell identity: Cell Reports Methods www.cell.com/cell-reports...
@hamarillo.bsky.social #TEHub #singlecell #genomics
A single-cell transposable element atlas of human cell identity: Cell Reports Methods www.cell.com/cell-reports...
@hamarillo.bsky.social #TEHub #singlecell #genomics
A single-cell transposable element atlas of human cell identity
Reyes-Gopar et al. introduce Stellarscope, a computational approach for quantifying
locus-specific transposable element expression in single-cell RNA sequencing data.
The authors profile human PBMCs a...
www.cell.com
July 22, 2025 at 3:52 PM
Thrilled to share this work! I am honored to learn from @mlbendall.bsky.social and so grateful for his guidance and mentorship.
Stellarscope is just the beginning!
There is so much to learn about TEs and now we can all explore the uncharted territory of single cell retro-genomics 🧬🔭
Stellarscope is just the beginning!
There is so much to learn about TEs and now we can all explore the uncharted territory of single cell retro-genomics 🧬🔭
Reposted by David Romero
This week @universitypress.cambridge.org has granted free access to all titles in the collection of Cambridge Elements in the Philosophy of Biology, edited by Grant Ramsey. There are many options to choose from! Happy reading! 📕👇 www.cambridge.org/core/publica... #philsci #HPbio #evosky #ISHPSSB2025
July 22, 2025 at 4:33 PM
This week @universitypress.cambridge.org has granted free access to all titles in the collection of Cambridge Elements in the Philosophy of Biology, edited by Grant Ramsey. There are many options to choose from! Happy reading! 📕👇 www.cambridge.org/core/publica... #philsci #HPbio #evosky #ISHPSSB2025
Reposted by David Romero
Thanks @lecteroide.bsky.social for the opportunity to share the efforts developed in MexOmics
www.the-scientist.com/mexomics-map...
www.the-scientist.com/mexomics-map...
MexOMICs Maps the Genetic and Social Landscape of Disease in Mexico
By focusing on twins and patients with lupus and Parkinson’s disease, a Mexican consortium is generating critical data to understand health and disease in the country.
www.the-scientist.com
July 2, 2025 at 6:51 PM
Thanks @lecteroide.bsky.social for the opportunity to share the efforts developed in MexOmics
www.the-scientist.com/mexomics-map...
www.the-scientist.com/mexomics-map...
Reposted by David Romero
1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs.
Full story here:
www.biorxiv.org/content/10.1...
Full story here:
www.biorxiv.org/content/10.1...
June 11, 2025 at 7:26 PM
Reposted by David Romero
The Fungal Kingdom as a Rosetta Stone for biological discovery – a long-time Current Biology advisory board member, Joseph Heitman, introduces the special issue on ‘The Fungi’. www.cell.com/current-biol...
The Fungal Kingdom as a Rosetta Stone for biological discovery
Long-time Current Biology advisory board member, Joseph Heitman, introduces this special
issue on ‘The Fungi’.
www.cell.com
June 11, 2025 at 7:32 PM
Reposted by David Romero
Nice work from Joseph Lobel on barcode-based #CRISPRi systems!
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Precise measurement of molecular phenotypes with barcode-based CRISPRi systems - Genome Biology
Genome-wide CRISPR-Cas9 screens have untangled regulatory networks driving diverse biological processes. Their success relies on interrogating specific molecular phenotypes and distinguishing key regu...
genomebiology.biomedcentral.com
June 1, 2025 at 2:04 PM
Nice work from Joseph Lobel on barcode-based #CRISPRi systems!
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Reposted by David Romero
How can physics contribute to understanding the evolution of complexity? Although great results have been produced over the last decades, some recent "theories" appear to ignore key ideas from evolutionary theory and are seriously flawed. Check this paper in PNAS www.pnas.org/doi/abs/10.1...
May 31, 2025 at 3:55 PM
How can physics contribute to understanding the evolution of complexity? Although great results have been produced over the last decades, some recent "theories" appear to ignore key ideas from evolutionary theory and are seriously flawed. Check this paper in PNAS www.pnas.org/doi/abs/10.1...
Reposted by David Romero
Novel insights into the genome organization of Rhizobiaceae: identification of linear plasmids https://www.biorxiv.org/content/10.1101/2025.05.29.656789v1
June 2, 2025 at 1:33 AM
Novel insights into the genome organization of Rhizobiaceae: identification of linear plasmids https://www.biorxiv.org/content/10.1101/2025.05.29.656789v1
Reposted by David Romero
This is a must-read. Csaba Szabó, the author of Unreliable, was approached by a paper mill, and he decided to conduct a sting operation. He documented how paper mills operate.
forbetterscience.com/2025/05/19/a...
forbetterscience.com/2025/05/19/a...
A Sting Inside a Papermill
“It’s clear that any academically corrupt individual — particularly one with editorial connections — could easily “place” dozens of these Anzen products into indexed journals and collect a ha…
forbetterscience.com
May 19, 2025 at 6:06 AM
This is a must-read. Csaba Szabó, the author of Unreliable, was approached by a paper mill, and he decided to conduct a sting operation. He documented how paper mills operate.
forbetterscience.com/2025/05/19/a...
forbetterscience.com/2025/05/19/a...
Reposted by David Romero
It's finally out people ✅🗞️! Check out the final version of our work exploring factors influencing the germline mutation rate and spectra on ~10,000 WGS family trios 🧬👨👩👦!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The impact of ancestral, genetic, and environmental influences on germline de novo mutation rates and spectra - Nature Communications
Here the authors analyze de novo mutations in >10,000 parent-offspring trios and find that ancestry and smoking independently associate with mutation rate, but that common genetic variants likely c...
www.nature.com
May 16, 2025 at 5:37 PM
It's finally out people ✅🗞️! Check out the final version of our work exploring factors influencing the germline mutation rate and spectra on ~10,000 WGS family trios 🧬👨👩👦!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by David Romero
The digital erosion of intellectual integrity: why misuse of generative AI is worse than plagiarism - AI & SOCIETY buff.ly/utMR3U9
May 1, 2025 at 10:18 PM
The digital erosion of intellectual integrity: why misuse of generative AI is worse than plagiarism - AI & SOCIETY buff.ly/utMR3U9
Reposted by David Romero
ASM strongly opposes the proposed cuts in the President’s fiscal year (FY) 2026 budget request to federal departments and agencies that fund science, research and public health programs. Read our statement: asm.org/articles/pol...
ASM Urges Congress to Reject President’s FY 2026 Budget Request | ASM.org
ASM strongly opposes the proposed cuts in the President’s fiscal year (FY) 2026 budget request to federal departments and agencies that fund science, research and public health programs.
asm.org
May 2, 2025 at 10:02 PM
ASM strongly opposes the proposed cuts in the President’s fiscal year (FY) 2026 budget request to federal departments and agencies that fund science, research and public health programs. Read our statement: asm.org/articles/pol...
Reposted by David Romero
JB Editor's Choice: Wessel, Johnson & Waters show that, unexpectedly, DNA damage repair is essential for the growth of pathogenic Vibrios on thiosulfate–citrate–bile salts–sucrose selective agar.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
April 28, 2025 at 11:52 AM
JB Editor's Choice: Wessel, Johnson & Waters show that, unexpectedly, DNA damage repair is essential for the growth of pathogenic Vibrios on thiosulfate–citrate–bile salts–sucrose selective agar.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by David Romero
I think that’s enough drinks for you, Molecular Biology! Pack up!
“Translation initiation from all 64 codons in E. coli”
academic.oup.com/nar/article/...
“Translation initiation from all 64 codons in E. coli”
academic.oup.com/nar/article/...
Measurements of translation initiation from all 64 codons in E. coli
Abstract. Our understanding of translation underpins our capacity to engineer living systems. The canonical start codon (AUG) and a few near-cognates (GUG,
academic.oup.com
April 23, 2025 at 2:49 PM
I think that’s enough drinks for you, Molecular Biology! Pack up!
“Translation initiation from all 64 codons in E. coli”
academic.oup.com/nar/article/...
“Translation initiation from all 64 codons in E. coli”
academic.oup.com/nar/article/...
Reposted by David Romero
Researchers pinpoint the genes responsible for the final three pea traits studied by Gregor Mendel more than 160 years ago
https://go.nature.com/3EC3eqT
https://go.nature.com/3EC3eqT
Century-old genetics mystery of Mendel’s peas finally solved
Researchers pinpoint the genes responsible for the final three pea traits studied by the famed citizen scientist.
go.nature.com
April 23, 2025 at 4:28 PM
Researchers pinpoint the genes responsible for the final three pea traits studied by Gregor Mendel more than 160 years ago
https://go.nature.com/3EC3eqT
https://go.nature.com/3EC3eqT
Reposted by David Romero
Que peligroso y que grave que estas señoras aspiren a un cargo tan importante
#HoyEnAnimal I Las abogadas Arely Reyes Terán e Ingrid de los Ángeles Tapia, quienes han tenido posturas contra las personas trans, buscan llegar a la SCJN, un hecho que activistas reprobaron por significar un retroceso a los derechos humanos en el país.
www.animalpolitico.com/politica/ele...
www.animalpolitico.com/politica/ele...
Elección judicial: abogadas transfóbicas y antiderechos buscan ser ministras de la Suprema Corte
www.animalpolitico.com
April 21, 2025 at 4:40 PM
Que peligroso y que grave que estas señoras aspiren a un cargo tan importante