David Tovey
@davidit.bsky.social
Co-Editor, Journal of Clinical Epidemiology
Emeritus Editor in Chief, Cochrane
Newish grandparent, run and cycle a bit.
Emeritus Editor in Chief, Cochrane
Newish grandparent, run and cycle a bit.
Reposted by David Tovey
Editors' Choice – September 2025 - Journal of Clinical Epidemiology by @davidit.bsky.social and @andreatricco.bsky.social www.jclinepi.com/article/S089...
Editors' Choice – September 2025
The Journal of Clinical Epidemiology takes a broad approach to the evidence ecosystem.
In any given issue, metaresearch topics focused on primary studies, evidence synthesis,
and guidelines can be fou...
www.jclinepi.com
October 10, 2025 at 10:24 AM
Editors' Choice – September 2025 - Journal of Clinical Epidemiology by @davidit.bsky.social and @andreatricco.bsky.social www.jclinepi.com/article/S089...
The challenges and opportunities of artificial intelligence and their impact on the journal - our Editors’ Choice for October issue www.jclinepi.com/article/S089...
The challenges and opportunities of artificial intelligence and their impact on the journal
As the keepers of the editorial “front door” of the journal, we are profoundly aware
of the myriad challenges and some opportunities that accompany the ubiquitous rise
of artificial intelligence (AI) ...
www.jclinepi.com
October 24, 2025 at 1:43 PM
The challenges and opportunities of artificial intelligence and their impact on the journal - our Editors’ Choice for October issue www.jclinepi.com/article/S089...
Reposted by David Tovey
In J Clin Epi I've published a couple of papers on questionnaire design pubmed.ncbi.nlm.nih.gov/12589865/ & pubmed.ncbi.nlm.nih.gov/18945586/ plus one on clinically important differences pubmed.ncbi.nlm.nih.gov/16360560/
Does questionnaire structure influence response in postal surveys? - PubMed
This study tested the effect of questionnaire structure on response, speed of return, and content of answers in a postal survey. All 259 patients aged 30-59 years who consulted with back pain at four ...
pubmed.ncbi.nlm.nih.gov
December 18, 2024 at 9:16 PM
In J Clin Epi I've published a couple of papers on questionnaire design pubmed.ncbi.nlm.nih.gov/12589865/ & pubmed.ncbi.nlm.nih.gov/18945586/ plus one on clinically important differences pubmed.ncbi.nlm.nih.gov/16360560/
Reposted by David Tovey
Reusing clinical trial data to consolidate and advance medical knowledge - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reusing clinical trial data to consolidate and advance medical knowledge
While data sharing holds great potential to maximize the value of research and reduce
waste, these benefits can only be fully realized if shared data are also effectively
reused. Yet data reuse remain...
www.jclinepi.com
September 28, 2025 at 12:34 PM
Reusing clinical trial data to consolidate and advance medical knowledge - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
For Monday crowd. INSPECT-SR, a tool to help you identify problematic (inc. fraudulent) RCTs, now available.
www.medrxiv.org/content/10.1...
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
www.medrxiv.org
September 8, 2025 at 7:22 AM
For Monday crowd. INSPECT-SR, a tool to help you identify problematic (inc. fraudulent) RCTs, now available.
Thanks for such a brilliant commentary. Transparency is necessary but not sufficient in many circumstances
@jclinepi.bsky.social kindly invited me to express my thoughts on handling #ConflictsOfInterest of authors of scholarly publications. bit.ly/431UYIQ
@nrin-integrity.bsky.social @opensciencenl.bsky.social @peerreviewcongress.bsky.social @davidit.bsky.social @lseimpactblog.bsky.social
@nrin-integrity.bsky.social @opensciencenl.bsky.social @peerreviewcongress.bsky.social @davidit.bsky.social @lseimpactblog.bsky.social
May 14, 2025 at 5:19 PM
Thanks for such a brilliant commentary. Transparency is necessary but not sufficient in many circumstances
Reposted by David Tovey
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review
To support systematic reviewers new to network meta-analysis (NMA), we (i) identified
and described published methods resources for conducting systematic reviews (SRs)
with NMA of randomized controlle...
www.jclinepi.com
March 22, 2025 at 1:25 PM
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
A scoping review identifies comments suggesting modifications to PRISMA-P 2015
To identify, summarise, and analyse published comments relevant to the PRISMA-P (Preferred
Items for Reporting Systematic reviews and Meta-Analyses Protocols) 2015 reporting
guideline for systematic r...
www.jclinepi.com
March 22, 2025 at 1:26 PM
A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Priority-setting criteria for clinical practice guideline development on rare genetic neurodevelopmental disorders: a Delphi study within the European Reference Network (ERN) ITHACA - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Priority-setting criteria for clinical practice guideline development on rare genetic neurodevelopmental disorders: a Delphi study within the European Reference Network (ERN) ITHACA
The prioritization of clinical practice guideline (CPG) efforts is particularly challenging
for rare genetic neurodevelopmental disorders given the large number of (ultra)rare
conditions and limited r...
www.jclinepi.com
March 22, 2025 at 1:27 PM
Priority-setting criteria for clinical practice guideline development on rare genetic neurodevelopmental disorders: a Delphi study within the European Reference Network (ERN) ITHACA - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Disappointing but perhaps not surprising
Epidemiology and reporting characteristics of systematic reviews of clinical prediction models:a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Epidemiology and reporting characteristics of systematic reviews of clinical prediction models:a scoping review
This study aimed to explore research trends and areas of interest in systematic reviews
(SRs) and meta-analyses of clinical prediction models (CPMs), while summarizing their
conduct and reporting char...
www.jclinepi.com
March 24, 2025 at 9:25 AM
Disappointing but perhaps not surprising
Reposted by David Tovey
Our message is one of hope, and we see this as a time of opportunity for leaders in the field to stand up for sound methods and high-quality science.
Editorial, April 2025
www.jclinepi.com/article/S089...
Editorial, April 2025
www.jclinepi.com/article/S089...
Editorial, April 2025
Drafting the monthly round-up of noteworthy manuscripts to be published in the corresponding
issue of the Journal of Clinical Epidemiology (JCE) is both a privilege and pleasure.
The task includes rer...
www.jclinepi.com
March 20, 2025 at 3:59 PM
Our message is one of hope, and we see this as a time of opportunity for leaders in the field to stand up for sound methods and high-quality science.
Editorial, April 2025
www.jclinepi.com/article/S089...
Editorial, April 2025
www.jclinepi.com/article/S089...
Reposted by David Tovey
New publication led by @proflouisemarston.bsky.social using multiple imputation to target a hypothetical estimand in a pandemic restriction-free world for a trial in
schizophrenia - demonstrating the potential impact of the pandemic on the trial results
schizophrenia - demonstrating the potential impact of the pandemic on the trial results
Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand
Many trials are affected by unforeseen events after recruitment has commenced. The
aim of this study is to explore a hypothetical strategy for dealing with an intercurrent
event that occurred during t...
www.jclinepi.com
March 18, 2025 at 8:27 AM
New publication led by @proflouisemarston.bsky.social using multiple imputation to target a hypothetical estimand in a pandemic restriction-free world for a trial in
schizophrenia - demonstrating the potential impact of the pandemic on the trial results
schizophrenia - demonstrating the potential impact of the pandemic on the trial results
Reposted by David Tovey
#keyconcepts Statistical strategies to analyze local control after radiotherapy - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Statistical strategies to analyze local control after radiotherapy
Historically, local progression, an outcome of effectiveness in curative radiotherapy,
has not always been statistically analyzed with the same method. This article aims
to elucidate the validity and ...
www.jclinepi.com
March 17, 2025 at 8:25 PM
#keyconcepts Statistical strategies to analyze local control after radiotherapy - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Calculating Follow-Up Completeness: a comparison of multiple methods under different simulated scenarios and a use-case - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Calculating Follow-Up Completeness: a comparison of multiple methods under different simulated scenarios and a use-case
Completeness of follow-up is a crucial aspect of data quality in cohort studies and
clinical trials. This study aims to provide an overview of different methods to calculate
follow-up completeness. Ad...
www.jclinepi.com
March 17, 2025 at 8:26 PM
Calculating Follow-Up Completeness: a comparison of multiple methods under different simulated scenarios and a use-case - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review
To support systematic reviewers new to network meta-analysis (NMA), we (i) identified
and described published methods resources for conducting systematic reviews (SRs)
with NMA of randomized controlle...
www.jclinepi.com
March 17, 2025 at 8:26 PM
Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
A scoping review identifies comments suggesting modifications to PRISMA-P 2015
To identify, summarise, and analyse published comments relevant to the PRISMA-P (Preferred
Items for Reporting Systematic reviews and Meta-Analyses Protocols) 2015 reporting
guideline for systematic r...
www.jclinepi.com
March 17, 2025 at 8:27 PM
A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Great to see journals based in the US and elsewhere standing up for scientific integrity.
PLOS has issued a statement on recent US Executive Orders and scientific integrity.
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
plos.io
February 22, 2025 at 1:30 PM
Great to see journals based in the US and elsewhere standing up for scientific integrity.
Reposted by David Tovey
Corrigendum to ʻMethodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies’. Journal of Clinical Epidemiology 145 (2022) 55–69 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Corrigendum to ʻMethodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies’. Journal of Clinical Epidemiology 145 (2022) 55–6...
In the original article, the supplementary file included our revisions as tracked
changes arising from the peer-review process. Attached is an updated supplementary
file where the tracked-changes have...
www.jclinepi.com
February 21, 2025 at 1:40 PM
Corrigendum to ʻMethodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies’. Journal of Clinical Epidemiology 145 (2022) 55–69 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Delighted to see our @jclinepi.bsky.social commentary on redundant publication and potential research waste in the field of reporting guidelines is now fully online and accessible for 50 days via this link: authors.elsevier.com/c/1kbcJ3BcJQ...
authors.elsevier.com
February 13, 2025 at 9:53 AM
Delighted to see our @jclinepi.bsky.social commentary on redundant publication and potential research waste in the field of reporting guidelines is now fully online and accessible for 50 days via this link: authors.elsevier.com/c/1kbcJ3BcJQ...
Reposted by David Tovey
You wait ages and then two arrive at once: reporting guidelines shouldn’t be like buses - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
You wait ages and then two arrive at once: reporting guidelines shouldn’t be like buses
www.jclinepi.com
February 2, 2025 at 9:06 PM
You wait ages and then two arrive at once: reporting guidelines shouldn’t be like buses - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores
We aimed to determine whether the existing risk of bias assessment tools addressed
constructs other than risk of bias or internal validity, and whether they used numerical
scores to express quality, w...
www.jclinepi.com
February 2, 2025 at 9:07 PM
Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Scoping review of registration of observational studies finds inadequate registration policies, increased registration, and a debate converging towards pro-registration - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Scoping review of registration of observational studies finds inadequate registration policies, increased registration, and a debate converging towards pro-registration
We aimed to examine a) the policies of national and international clinical trial registries
regarding observational studies; b) the time-trends of observational study registration;
c) the published ar...
www.jclinepi.com
February 5, 2025 at 7:54 PM
Scoping review of registration of observational studies finds inadequate registration policies, increased registration, and a debate converging towards pro-registration - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Heterogeneity across outcomes in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors in chronic heart failure: cross-sectional study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Heterogeneity across outcomes in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors in chronic heart failure: cross-sectional study
This study aimed to analyze the outcomes, outcome domains, and prevalence of the use
of clinical outcome endpoints (COE) in clinical trials on sodium-glucose cotransporter
2 (SGLT2) inhibitors for chr...
www.jclinepi.com
February 5, 2025 at 7:55 PM
Heterogeneity across outcomes in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors in chronic heart failure: cross-sectional study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Visualizing the Value of Diagnostic Tests and Prediction Models, Part I. Introduction and Expected Gain in Utility as a Function of Pre-Test Probability - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Visualizing the Value of Diagnostic Tests and Prediction Models, Part I. Introduction and Expected Gain in Utility as a Function of Pre-Test Probability
Expected gain in utility (EGU) and EGU graphs are used to evaluate diagnostic tests
and risk prediction models. EGU is the expected gain or loss in utility of treating
or testing relative to not treat...
www.jclinepi.com
February 5, 2025 at 7:56 PM
Visualizing the Value of Diagnostic Tests and Prediction Models, Part I. Introduction and Expected Gain in Utility as a Function of Pre-Test Probability - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by David Tovey
Visualizing the Value of Diagnostic Tests and Prediction Models, Part II. Net Benefit Graphs: Net Benefit as a Function of the Exchange Rate - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Visualizing the Value of Diagnostic Tests and Prediction Models, Part II. Net Benefit Graphs: Net Benefit as a Function of the Exchange Rate
Net benefit (NB) calculations and NB graphs are used to evaluate diagnostic tests
and risk prediction models. NB is the expected gain or loss in utility of treating
or testing relative to not treating...
www.jclinepi.com
February 5, 2025 at 7:57 PM
Visualizing the Value of Diagnostic Tests and Prediction Models, Part II. Net Benefit Graphs: Net Benefit as a Function of the Exchange Rate - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...