Fillip Port
@crisprflydesign.bsky.social
Scientist at the German Cancer Reseach Center in Heidelberg. We develop genome engineering tools for functional genomics. #CRISPR #Drosophila #openscience
CRISPR mutagenesis is also not perfect. A common limitation is generation of genetic mosaics, where only some cells carry gene knockouts. But our new generation of tools substatially improves on that. Described in the preprint below with flies on their way to VDRC:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 26, 2025 at 7:29 AM
CRISPR mutagenesis is also not perfect. A common limitation is generation of genetic mosaics, where only some cells carry gene knockouts. But our new generation of tools substatially improves on that. Described in the preprint below with flies on their way to VDRC:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Probably my favorite experiment we ran this year. Screening #CRISPR activity over entire chromosome arms in living animals. From:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 17, 2024 at 12:51 PM
Probably my favorite experiment we ran this year. Screening #CRISPR activity over entire chromosome arms in living animals. From:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...