Covid Is Not Over
@covidisnotover24.bsky.social
Covid is a multi-systemic, vascular, thrombotic, neurotropic, oncogenic Severe Acute Respiratory Syndrome. Clean air/respirators/Far UV/ vaccines. Fibromyalgia/ME/poly arthritis/asthma. Love dogs.
Reposted by Covid Is Not Over
Genetic sequencing of the #H5N1 #birdflu virus from the Canadian teenager shows worrying changes. It doesn't mean H5 is taking off — but it's a reminder that it might, says @scottehensley.bsky.social. "This is exactly the scenario that we fear.” www.statnews.com/2024/11/18/b...
H5N1 bird flu virus in Canadian teenager displays mutations demonstrating virus’ risk
The H5N1 virus that infected a Canadian teen appears not to have spread, but it shows signs of mutation that makes flu virologists nervous.
www.statnews.com
November 18, 2024 at 9:30 PM
Genetic sequencing of the #H5N1 #birdflu virus from the Canadian teenager shows worrying changes. It doesn't mean H5 is taking off — but it's a reminder that it might, says @scottehensley.bsky.social. "This is exactly the scenario that we fear.” www.statnews.com/2024/11/18/b...
Reposted by Covid Is Not Over
California Department of Public Health investigating a possible bird flu case in a child who has had mild respiratory symptoms and is recovering at home. Children from a daycare setting also being tested as a preventive step, although no evidence of additional spread
www.cdph.ca.gov/Programs/OPA...
www.cdph.ca.gov/Programs/OPA...
November 19, 2024 at 6:18 PM
California Department of Public Health investigating a possible bird flu case in a child who has had mild respiratory symptoms and is recovering at home. Children from a daycare setting also being tested as a preventive step, although no evidence of additional spread
www.cdph.ca.gov/Programs/OPA...
www.cdph.ca.gov/Programs/OPA...
Reposted by Covid Is Not Over
California Dept of Public Health confirms that the child tested positive for an #H5 #birdflu virus. Still needs to be confirmed by #CDC.
November 19, 2024 at 5:59 PM
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Something to cheer up my fellow travellers on the planet Earth ride…
They actually have stockpiled, and are using, N95 respirators.
www.ems1.com/infectious-d...
They actually have stockpiled, and are using, N95 respirators.
www.ems1.com/infectious-d...
Calif. health officials dip into pandemic stockpile in response to bird flu
Over 2 million pieces of PPE have been distributed to farmworkers in response to confirmed human cases of bird flu
www.ems1.com
November 18, 2024 at 10:35 AM
Something to cheer up my fellow travellers on the planet Earth ride…
They actually have stockpiled, and are using, N95 respirators.
www.ems1.com/infectious-d...
They actually have stockpiled, and are using, N95 respirators.
www.ems1.com/infectious-d...
Reposted by Covid Is Not Over
For example just saying the Novavax vaccine has a mechanism and side effect profile similar to flu shots could improve uptake of COVID19 boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
November 17, 2024 at 8:26 PM
For example just saying the Novavax vaccine has a mechanism and side effect profile similar to flu shots could improve uptake of COVID19 boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
Reposted by Covid Is Not Over
Excellent discussion by Daniel Park of 3 recent papers on the Novavax SARSCoV2 vaccine. Better durability and cross reactivity and milder side effects than RNA vax.
That's the way it appeared from early data, but it's good to see that confirmed.
threadreaderapp.com/thread/18576...
That's the way it appeared from early data, but it's good to see that confirmed.
threadreaderapp.com/thread/18576...
Thread by @Daniel_E_Park on Thread Reader App
@Daniel_E_Park: A trio of Novavax preprints, showing 1) remarkable durability >6 months, 2) cross protection against newer variants, and 3) low reactogenicity (side effects), supporting NVX as an exce...
threadreaderapp.com
November 17, 2024 at 7:51 AM
Excellent discussion by Daniel Park of 3 recent papers on the Novavax SARSCoV2 vaccine. Better durability and cross reactivity and milder side effects than RNA vax.
That's the way it appeared from early data, but it's good to see that confirmed.
threadreaderapp.com/thread/18576...
That's the way it appeared from early data, but it's good to see that confirmed.
threadreaderapp.com/thread/18576...
Reposted by Covid Is Not Over
SARS-CoV-2 suppresses the expression of mitochondrial genes needed for energy production, redirecting cells to produce more viral particles.
Mitochondrial dysfunction and gene suppression continue in organs like the heart, kidney, liver, and lymph nodes.
www.nih.gov/news-events/...
Mitochondrial dysfunction and gene suppression continue in organs like the heart, kidney, liver, and lymph nodes.
www.nih.gov/news-events/...
SARS-CoV-2 can cause lasting damage to cells’ energy production
SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body.
www.nih.gov
November 18, 2024 at 2:23 AM
SARS-CoV-2 suppresses the expression of mitochondrial genes needed for energy production, redirecting cells to produce more viral particles.
Mitochondrial dysfunction and gene suppression continue in organs like the heart, kidney, liver, and lymph nodes.
www.nih.gov/news-events/...
Mitochondrial dysfunction and gene suppression continue in organs like the heart, kidney, liver, and lymph nodes.
www.nih.gov/news-events/...
Reposted by Covid Is Not Over
Recent clade 2.3.4.4b human cases have been somewhat mild. However, the teenager from British Columbia appears to be very sick and in the intensive care unit. It is possible that HA Q226X has contributed to this. We need to closely monitor this situation and increase our surveillance efforts. 5/
November 16, 2024 at 3:19 PM
Recent clade 2.3.4.4b human cases have been somewhat mild. However, the teenager from British Columbia appears to be very sick and in the intensive care unit. It is possible that HA Q226X has contributed to this. We need to closely monitor this situation and increase our surveillance efforts. 5/
Reposted by Covid Is Not Over
Residue 226 of the British Columbia human HA sequence is ambiguous. This can happen with poor sequencing, but in this case I think it is likely because of mixed viral sequence, given the residue # and apparent unambiguous sequence of neighboring residues. 4/
November 16, 2024 at 3:19 PM
Residue 226 of the British Columbia human HA sequence is ambiguous. This can happen with poor sequencing, but in this case I think it is likely because of mixed viral sequence, given the residue # and apparent unambiguous sequence of neighboring residues. 4/
Reposted by Covid Is Not Over
Here is a link to @jbloomlab.bsky.social paper showing how mutations at H5 residue 226 (and other residues) can affect receptor specificity. 3/
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
H5 influenza is considered a potential pandemic threat. Using deep mutational scanning, this work reveals how the >10,000 different possible amino-acid mutations in hemagglutinin affect cell entry, re...
journals.plos.org
November 16, 2024 at 3:19 PM
Here is a link to @jbloomlab.bsky.social paper showing how mutations at H5 residue 226 (and other residues) can affect receptor specificity. 3/
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Covid Is Not Over
For example, take a look at this paper that we recently published together with @jbloomlab.bsky.social . Jesse's lab led the study and found that single mutations at residue 226 dramatically changed H5 receptor binding preference from a2-3 (bird receptor) to a2-6 (human receptor) binding. 2/
November 16, 2024 at 3:19 PM
For example, take a look at this paper that we recently published together with @jbloomlab.bsky.social . Jesse's lab led the study and found that single mutations at residue 226 dramatically changed H5 receptor binding preference from a2-3 (bird receptor) to a2-6 (human receptor) binding. 2/
Reposted by Covid Is Not Over
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
November 16, 2024 at 3:19 PM
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
Reposted by Covid Is Not Over
Reposted by Covid Is Not Over
November 16, 2024 at 1:14 AM
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#YallMasking to protect yourself and those that you love?
November 18, 2024 at 1:23 AM
#YallMasking to protect yourself and those that you love?
Reposted by Covid Is Not Over
Repeated COVID-19 Infections: A Jenga Tower of Hidden Damage
Imagine playing a game of Jenga. You carefully pull out blocks, each removal making the tower a bit shakier. (1/26)
Imagine playing a game of Jenga. You carefully pull out blocks, each removal making the tower a bit shakier. (1/26)
October 19, 2024 at 5:59 PM
Repeated COVID-19 Infections: A Jenga Tower of Hidden Damage
Imagine playing a game of Jenga. You carefully pull out blocks, each removal making the tower a bit shakier. (1/26)
Imagine playing a game of Jenga. You carefully pull out blocks, each removal making the tower a bit shakier. (1/26)
Reposted by Covid Is Not Over
Everyone is vulnerable
#WearAMask #MaskUp
#CovidIsNotOver #CovidIsntOver #CovidIsAirborne #StopLongCovid #BringBackMasks #KeepMasksInHealthcare
#WearAMask #MaskUp
#CovidIsNotOver #CovidIsntOver #CovidIsAirborne #StopLongCovid #BringBackMasks #KeepMasksInHealthcare
November 17, 2024 at 1:37 AM
Everyone is vulnerable
#WearAMask #MaskUp
#CovidIsNotOver #CovidIsntOver #CovidIsAirborne #StopLongCovid #BringBackMasks #KeepMasksInHealthcare
#WearAMask #MaskUp
#CovidIsNotOver #CovidIsntOver #CovidIsAirborne #StopLongCovid #BringBackMasks #KeepMasksInHealthcare
Reposted by Covid Is Not Over
Jay Bhattacharya advocated for sending teachers back into schools in 2020 before vaccines were available & basically was okay with it cuz if teachers got COVID b/c most of them wouldn't die. He may be next NIH director for Trump. @mayachavez.bsky.social
November 16, 2024 at 10:17 PM
Jay Bhattacharya advocated for sending teachers back into schools in 2020 before vaccines were available & basically was okay with it cuz if teachers got COVID b/c most of them wouldn't die. He may be next NIH director for Trump. @mayachavez.bsky.social
Reposted by Covid Is Not Over
How COVID-19 messes with bone marrow.
COVID-19 doesn’t just stop at your lungs, heart—it can invade the bone marrow itself. The virus and its long-term persistence in the body are now being connected to deeper, systemic damage
open.substack.com/pub/notesfor...
COVID-19 doesn’t just stop at your lungs, heart—it can invade the bone marrow itself. The virus and its long-term persistence in the body are now being connected to deeper, systemic damage
open.substack.com/pub/notesfor...
Are We Screwed? Bone Marrow Destruction - Covid F’d us?
The world has spent much of the past few years grappling with the visible destruction caused by COVID-19.
open.substack.com
November 15, 2024 at 9:00 PM
How COVID-19 messes with bone marrow.
COVID-19 doesn’t just stop at your lungs, heart—it can invade the bone marrow itself. The virus and its long-term persistence in the body are now being connected to deeper, systemic damage
open.substack.com/pub/notesfor...
COVID-19 doesn’t just stop at your lungs, heart—it can invade the bone marrow itself. The virus and its long-term persistence in the body are now being connected to deeper, systemic damage
open.substack.com/pub/notesfor...
Reposted by Covid Is Not Over
With the XEC variant on the way to dominance in most places, and XEC waves starting to show in COVID metrics, it is time to ponder which variant will drive the next wave after XEC.
Here are the leading contenders: LP.8.1, MC.10.2 and NP.1.
More details:
aus.social/@mike_honey_...
Here are the leading contenders: LP.8.1, MC.10.2 and NP.1.
More details:
aus.social/@mike_honey_...
Mike Honey (@mike_honey_@aus.social)
Attached: 1 image
With the XEC variant on the way to dominance in most places, and XEC waves starting to show in COVID metrics, it is time to ponder which variant will drive the next wave after XEC.
...
aus.social
November 16, 2024 at 11:25 PM
With the XEC variant on the way to dominance in most places, and XEC waves starting to show in COVID metrics, it is time to ponder which variant will drive the next wave after XEC.
Here are the leading contenders: LP.8.1, MC.10.2 and NP.1.
More details:
aus.social/@mike_honey_...
Here are the leading contenders: LP.8.1, MC.10.2 and NP.1.
More details:
aus.social/@mike_honey_...
Reposted by Covid Is Not Over
Sounds about right.
November 16, 2024 at 8:15 PM
Sounds about right.
Reposted by Covid Is Not Over
