Covid Is Not Over
@covidisnotover24.bsky.social
Covid is a multi-systemic, vascular, thrombotic, neurotropic, oncogenic Severe Acute Respiratory Syndrome. Clean air/respirators/Far UV/ vaccines. Fibromyalgia/ME/poly arthritis/asthma. Love dogs.
Reposted by Covid Is Not Over
For example just saying the Novavax vaccine has a mechanism and side effect profile similar to flu shots could improve uptake of COVID19 boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
November 17, 2024 at 8:26 PM
For example just saying the Novavax vaccine has a mechanism and side effect profile similar to flu shots could improve uptake of COVID19 boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
95% of people don't know that and assume all COVID vaccines have the same side effect profile of RNA vaccines which is clearly worse than flu boosters.
Reposted by Covid Is Not Over
Recent clade 2.3.4.4b human cases have been somewhat mild. However, the teenager from British Columbia appears to be very sick and in the intensive care unit. It is possible that HA Q226X has contributed to this. We need to closely monitor this situation and increase our surveillance efforts. 5/
November 16, 2024 at 3:19 PM
Recent clade 2.3.4.4b human cases have been somewhat mild. However, the teenager from British Columbia appears to be very sick and in the intensive care unit. It is possible that HA Q226X has contributed to this. We need to closely monitor this situation and increase our surveillance efforts. 5/
Reposted by Covid Is Not Over
Residue 226 of the British Columbia human HA sequence is ambiguous. This can happen with poor sequencing, but in this case I think it is likely because of mixed viral sequence, given the residue # and apparent unambiguous sequence of neighboring residues. 4/
November 16, 2024 at 3:19 PM
Residue 226 of the British Columbia human HA sequence is ambiguous. This can happen with poor sequencing, but in this case I think it is likely because of mixed viral sequence, given the residue # and apparent unambiguous sequence of neighboring residues. 4/
Reposted by Covid Is Not Over
Here is a link to @jbloomlab.bsky.social paper showing how mutations at H5 residue 226 (and other residues) can affect receptor specificity. 3/
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
H5 influenza is considered a potential pandemic threat. Using deep mutational scanning, this work reveals how the >10,000 different possible amino-acid mutations in hemagglutinin affect cell entry, re...
journals.plos.org
November 16, 2024 at 3:19 PM
Here is a link to @jbloomlab.bsky.social paper showing how mutations at H5 residue 226 (and other residues) can affect receptor specificity. 3/
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Covid Is Not Over
For example, take a look at this paper that we recently published together with @jbloomlab.bsky.social . Jesse's lab led the study and found that single mutations at residue 226 dramatically changed H5 receptor binding preference from a2-3 (bird receptor) to a2-6 (human receptor) binding. 2/
November 16, 2024 at 3:19 PM
For example, take a look at this paper that we recently published together with @jbloomlab.bsky.social . Jesse's lab led the study and found that single mutations at residue 226 dramatically changed H5 receptor binding preference from a2-3 (bird receptor) to a2-6 (human receptor) binding. 2/