Nick Corriveau-Lecavalier PhD, LP
@corriveaunick.bsky.social
Neuropsychology Fellow | Assistant Professor of Neurology and Psychology | Neurology AI Program | Mayo Clinic | Aging, Neurodegenerative Diseases, Brain Imaging
Reposted by Nick Corriveau-Lecavalier PhD, LP
A man who had severe depression for more than 30 years has "experienced joy" after undergoing bespoke brain stimulation.
Brain implant lets man 'experience joy' for the first time in decades
A device that has been likened to a pacemaker for the brain has given a man with severe depression great relief
www.newscientist.com
August 20, 2025 at 8:52 AM
A man who had severe depression for more than 30 years has "experienced joy" after undergoing bespoke brain stimulation.
For those attending #AAIC25, please consider our session "Improving Clinical Trials for Atypical Alzheimer’s Disease: A Call to Action" on Tuesday July 29th at 2PM!
July 25, 2025 at 12:33 PM
For those attending #AAIC25, please consider our session "Improving Clinical Trials for Atypical Alzheimer’s Disease: A Call to Action" on Tuesday July 29th at 2PM!
Our team had worked relentlessly over the past years to make this tool, StateViewer, come to life and available to all neurologists across the Mayo Clinic Entreprise.
A great example of ethical AI use to enhance decision-making in real-life clinical scenarios.
A great example of ethical AI use to enhance decision-making in real-life clinical scenarios.
newsnetwork.mayoclinic.org
July 3, 2025 at 5:02 PM
Our team had worked relentlessly over the past years to make this tool, StateViewer, come to life and available to all neurologists across the Mayo Clinic Entreprise.
A great example of ethical AI use to enhance decision-making in real-life clinical scenarios.
A great example of ethical AI use to enhance decision-making in real-life clinical scenarios.
Many clinicians are uncomfortable talking about death. We far too often over-treat illness at all cost, losing sight of what truly matters - quality of life. Excellent episode about death, and how to approach this topic with patients and loved ones: freakonomics.com/podcast/does...
Does Death Have to Be a Death Sentence? (Update) - Freakonomics
Does Death Have to Be a Death Sentence? (Update) - Freakonomics
freakonomics.com
June 5, 2025 at 6:07 PM
Many clinicians are uncomfortable talking about death. We far too often over-treat illness at all cost, losing sight of what truly matters - quality of life. Excellent episode about death, and how to approach this topic with patients and loved ones: freakonomics.com/podcast/does...
Reposted by Nick Corriveau-Lecavalier PhD, LP
📆 Mark your calendars for #AAIC25!
Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29!
@rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social
Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29!
@rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social
June 4, 2025 at 2:10 PM
📆 Mark your calendars for #AAIC25!
Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29!
@rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social
Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29!
@rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social
Reposted by Nick Corriveau-Lecavalier PhD, LP
After an “update in cognitive & behavioral neurology” talk at AAN, I was asked to chat on the Neurology podcast (also no bsky but my request to change that has been noted!) about some of the content. We focused on plasma biomarkers. Still can’t listen to myself lol.
youtu.be/7wWOrZenplQ?...
youtu.be/7wWOrZenplQ?...
Understanding Blood-Based Biomarkers in Alzheimer Disease
YouTube video by Neurology Journal
youtu.be
May 7, 2025 at 6:18 PM
After an “update in cognitive & behavioral neurology” talk at AAN, I was asked to chat on the Neurology podcast (also no bsky but my request to change that has been noted!) about some of the content. We focused on plasma biomarkers. Still can’t listen to myself lol.
youtu.be/7wWOrZenplQ?...
youtu.be/7wWOrZenplQ?...
Reposted by Nick Corriveau-Lecavalier PhD, LP
🚨 Video alert: I was able to share our @mayoclinic.org work on #NeuroAI at #GoogleCloudNext, including how we hope to scale expert interpretation of brain scans to improve dementia care.
🧠 Watch here: youtu.be/lJ1SVeeFWZQ?...
#DigitalHealth #AI #endalz
🧠 Watch here: youtu.be/lJ1SVeeFWZQ?...
#DigitalHealth #AI #endalz
Gopal Srinivasan, Deloitte Consulting LLP & Dr. David Jones, Mayo Clinic | Google Cloud Next 2025
YouTube video by SiliconANGLE theCUBE
youtu.be
April 13, 2025 at 5:28 PM
🚨 Video alert: I was able to share our @mayoclinic.org work on #NeuroAI at #GoogleCloudNext, including how we hope to scale expert interpretation of brain scans to improve dementia care.
🧠 Watch here: youtu.be/lJ1SVeeFWZQ?...
#DigitalHealth #AI #endalz
🧠 Watch here: youtu.be/lJ1SVeeFWZQ?...
#DigitalHealth #AI #endalz
Reposted by Nick Corriveau-Lecavalier PhD, LP
Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...
March 6, 2025 at 7:16 PM
Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...
The one case featured across LATE-NC papers appeared to have multiple neuropathologies in the medial temporal lobe at autopsy. Is pure LATE-NC a real thing? This is why we framed this syndrome as a limbic degeneration problem that is agnostic to underlying pathology academic.oup.com/braincomms/a...
February 20, 2025 at 1:47 PM
The one case featured across LATE-NC papers appeared to have multiple neuropathologies in the medial temporal lobe at autopsy. Is pure LATE-NC a real thing? This is why we framed this syndrome as a limbic degeneration problem that is agnostic to underlying pathology academic.oup.com/braincomms/a...
If you are at #INS please stop by the non-AD session at 10:45 on Saturday to hear my talk about the clinical syndrome associated with limbic degeneration in old age!
February 14, 2025 at 3:58 PM
If you are at #INS please stop by the non-AD session at 10:45 on Saturday to hear my talk about the clinical syndrome associated with limbic degeneration in old age!
Can't understate the importance of this paper by Deepti Putcha & LEADS...
EOAD is not an "earlier" amnestic phenotype. It's a fundamentally different disease. It's about time dysexecutive phenotypes receive the recognition they deserve.
alzres.biomedcentral.com/articles/10....
EOAD is not an "earlier" amnestic phenotype. It's a fundamentally different disease. It's about time dysexecutive phenotypes receive the recognition they deserve.
alzres.biomedcentral.com/articles/10....
February 7, 2025 at 3:01 PM
Can't understate the importance of this paper by Deepti Putcha & LEADS...
EOAD is not an "earlier" amnestic phenotype. It's a fundamentally different disease. It's about time dysexecutive phenotypes receive the recognition they deserve.
alzres.biomedcentral.com/articles/10....
EOAD is not an "earlier" amnestic phenotype. It's a fundamentally different disease. It's about time dysexecutive phenotypes receive the recognition they deserve.
alzres.biomedcentral.com/articles/10....
Reposted by Nick Corriveau-Lecavalier PhD, LP
Excited to be chairing a new Stanford faculty search in Neurology. We are looking for MD and MD/PhD physician-scientists who have a strong research program (wet lab or dry lab) and who are also excellent clinicians. Please spread the word. Here's the link to the job posting:
lnkd.in/d6REUGfM
lnkd.in/d6REUGfM
January 31, 2025 at 6:25 PM
Excited to be chairing a new Stanford faculty search in Neurology. We are looking for MD and MD/PhD physician-scientists who have a strong research program (wet lab or dry lab) and who are also excellent clinicians. Please spread the word. Here's the link to the job posting:
lnkd.in/d6REUGfM
lnkd.in/d6REUGfM
K99/R00 proposal is DONE. Can't understate how stressful this process was. Fingers crossed 🤞🏻
January 22, 2025 at 5:58 PM
K99/R00 proposal is DONE. Can't understate how stressful this process was. Fingers crossed 🤞🏻
Large-scale studies often report findings about what seems to be an unusual "young-onset, aggressive" subtype of AD. Clinically we call this dysexecutive AD. We clearly define the distinct clinical and biological features of this AD variant here --> academic.oup.com/braincomms/a...
Progressive dysexecutive syndrome due to Alzheimer’s disease: a description of 55 cases and comparison to other phenotypes
We present a retrospective case series of 55 individuals presenting with a progressive dysexecutive syndrome with biomarker evidence of Alzheimer’s disease
academic.oup.com
January 15, 2025 at 2:46 PM
Large-scale studies often report findings about what seems to be an unusual "young-onset, aggressive" subtype of AD. Clinically we call this dysexecutive AD. We clearly define the distinct clinical and biological features of this AD variant here --> academic.oup.com/braincomms/a...
Excited to collaborate on this NIH-funded project on rapidly progressive dementias.
newsnetwork.mayoclinic.org
January 12, 2025 at 5:04 PM
Excited to collaborate on this NIH-funded project on rapidly progressive dementias.
Great Friday ahead 🫠
January 10, 2025 at 3:27 PM
Great Friday ahead 🫠
Reposted by Nick Corriveau-Lecavalier PhD, LP
I am officially seeking a postdoc to work with us on software development for de-facing and PET quantification. Please pass along to any eligible candidates you may know. jobs.mayoclinic.org/job/rocheste...
January 3, 2025 at 4:05 PM
I am officially seeking a postdoc to work with us on software development for de-facing and PET quantification. Please pass along to any eligible candidates you may know. jobs.mayoclinic.org/job/rocheste...
Reposted by Nick Corriveau-Lecavalier PhD, LP
One of many ways to usefully prognosticate for patients using FDG-PET: www.sciencedirect.com/science/arti...
Brain Metabolic Resilience in Alzheimer's Disease: A Predictor of Cognitive Decline and Conversion to Dementia
Brain atrophy measured by structural imaging has been used to quantify resilience against neurodegeneration in Alzheimer's disease. Considering glucos…
www.sciencedirect.com
January 2, 2025 at 3:43 AM
One of many ways to usefully prognosticate for patients using FDG-PET: www.sciencedirect.com/science/arti...
Merry Christmas from me and the #1 packers fan
December 26, 2024 at 3:25 AM
Merry Christmas from me and the #1 packers fan
Been asked to review like 5 papers this week, right before PTO and Holidays. Am I alone? Ugh.
December 20, 2024 at 10:04 PM
Been asked to review like 5 papers this week, right before PTO and Holidays. Am I alone? Ugh.
Check out our new paper on the identification of ultra-rapid progressive dementia (with case studies & review):
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Identification and diagnosis of ultra-rapid progressive dementia: evidence from a prospective cohort study and systematic literature review - Journal of Neurology
Background and objectives The term rapid progressive dementia (RPD) may be applied to patients who develop dementia within 1 year or complete incapacitation within 2 years of the first symptom of impa...
link.springer.com
December 19, 2024 at 12:32 PM
Check out our new paper on the identification of ultra-rapid progressive dementia (with case studies & review):
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Nick Corriveau-Lecavalier PhD, LP
Reposted by Nick Corriveau-Lecavalier PhD, LP
Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP
doi.org/10.1007/s004...
doi.org/10.1007/s004...
Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies - Acta Neuropathologica
Tau PET has attracted increasing interest as an imaging biomarker for 4-repeat (4R)-tauopathy progressive supranuclear palsy (PSP). However, the translation of in vitro 4R-tau binding to in vivo tau P...
doi.org
November 25, 2024 at 5:59 PM
Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP
doi.org/10.1007/s004...
doi.org/10.1007/s004...
Finished a first draft of my K99 😮💨. Not at the finish line yet, but looking forward to a well-deserved rest over the Thanksgiving holiday.
November 25, 2024 at 1:42 PM
Finished a first draft of my K99 😮💨. Not at the finish line yet, but looking forward to a well-deserved rest over the Thanksgiving holiday.