Chris Clarkson
@chrsclrksn.bsky.social
Bioinformatician working on tandem repeats
Reposted by Chris Clarkson
Time for a short thread! We developed HiddenFoot, a biophysics-inspired approach to decode single-molecule footprinting data and infer TF, nucleosome, and RNA Pol II binding profiles on individual DNA molecules. One molecule at a time! www.biorxiv.org/content/10.1...
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May 19, 2025 at 6:55 PM
Time for a short thread! We developed HiddenFoot, a biophysics-inspired approach to decode single-molecule footprinting data and infer TF, nucleosome, and RNA Pol II binding profiles on individual DNA molecules. One molecule at a time! www.biorxiv.org/content/10.1...
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Reposted by Chris Clarkson
We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and beyond www.jobs.ac.uk/job/DMK060/s.... Application deadline: 21st April 2025
Senior Research Officer at University of Essex
Searching for an academic job? Explore this Senior Research Officer opening on jobs.ac.uk! Click to view more details and browse other academic jobs.
www.jobs.ac.uk
March 27, 2025 at 9:15 AM
We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and beyond www.jobs.ac.uk/job/DMK060/s.... Application deadline: 21st April 2025
Reposted by Chris Clarkson
March 25, 2025 at 8:04 PM
Really interesting looking position- highly recommend!
www.jobs.gla.ac.uk/job/research...
www.jobs.gla.ac.uk/job/research...
Research Assistant/Associate
Job PurposeTo contribute to/make a leading contribution to the project ‘Somatic instability in Huntington disease’ working with Prof. Darren Monckton. Prof Monckton’s team use human genetic analyse...
www.jobs.gla.ac.uk
February 14, 2025 at 10:20 AM
Really interesting looking position- highly recommend!
www.jobs.gla.ac.uk/job/research...
www.jobs.gla.ac.uk/job/research...
Reposted by Chris Clarkson
More thoughts on these issues here: If genomics is the answer, what's the question? www.wiringthebrain.com/2018/12/if-g...
If genomics is the answer, what's the question? A commentary on PsychENCODE
There was much excitement in the press and in the psychiatric research community recently as a flurry of papers was p...
www.wiringthebrain.com
January 22, 2025 at 2:16 PM
More thoughts on these issues here: If genomics is the answer, what's the question? www.wiringthebrain.com/2018/12/if-g...
Reposted by Chris Clarkson
Most previous epigenetic age predictors were focused on DNA methylation. Our own model suggested nucleosome positioning as an age predictor a year ago onlinelibrary.wiley.com/doi/full/10....
Aging clock based on nucleosome reorganisation derived from cell‐free DNA
We show that aging is associated with an increase in the distance between nucleosomes, which can be used to predict a person's age and conduct age classification. We developed the first aging clock b...
onlinelibrary.wiley.com
January 1, 2025 at 8:50 PM
Most previous epigenetic age predictors were focused on DNA methylation. Our own model suggested nucleosome positioning as an age predictor a year ago onlinelibrary.wiley.com/doi/full/10....
Reposted by Chris Clarkson
An essay in Nature discusses how it’s an astonishing achievement that all of statistics and much of science depends on probability considering no one’s sure what it is. 🧪
Why probability probably doesn’t exist (but it is useful to act like it does)
All of statistics and much of science depends on probability — an astonishing achievement, considering no one’s really sure what it is.
go.nature.com
December 21, 2024 at 8:31 PM
An essay in Nature discusses how it’s an astonishing achievement that all of statistics and much of science depends on probability considering no one’s sure what it is. 🧪
The lab of (amazing!) Arianna Tucci and I are delighted to share our published work on the repeat expansion locus in THAP11:
movementdisorders.onlinelibrary.wiley.com
December 12, 2024 at 2:31 PM
The lab of (amazing!) Arianna Tucci and I are delighted to share our published work on the repeat expansion locus in THAP11:
Reposted by Chris Clarkson
My fav starter packs so far, a thread:
stats: go.bsky.app/Ki7PjpS
stats: go.bsky.app/7TBN5rX
causal inference: go.bsky.app/FdemGAZ
package devs: go.bsky.app/N1569Qh
data peeps: go.bsky.app/8TdEfdK
medical stats: go.bsky.app/ArqEz36
bioinformatics: go.bsky.app/Ha64Gmv
r-ladies: go.bsky.app/Vgxwa2F
stats: go.bsky.app/Ki7PjpS
stats: go.bsky.app/7TBN5rX
causal inference: go.bsky.app/FdemGAZ
package devs: go.bsky.app/N1569Qh
data peeps: go.bsky.app/8TdEfdK
medical stats: go.bsky.app/ArqEz36
bioinformatics: go.bsky.app/Ha64Gmv
r-ladies: go.bsky.app/Vgxwa2F
October 26, 2024 at 7:23 PM
My fav starter packs so far, a thread:
stats: go.bsky.app/Ki7PjpS
stats: go.bsky.app/7TBN5rX
causal inference: go.bsky.app/FdemGAZ
package devs: go.bsky.app/N1569Qh
data peeps: go.bsky.app/8TdEfdK
medical stats: go.bsky.app/ArqEz36
bioinformatics: go.bsky.app/Ha64Gmv
r-ladies: go.bsky.app/Vgxwa2F
stats: go.bsky.app/Ki7PjpS
stats: go.bsky.app/7TBN5rX
causal inference: go.bsky.app/FdemGAZ
package devs: go.bsky.app/N1569Qh
data peeps: go.bsky.app/8TdEfdK
medical stats: go.bsky.app/ArqEz36
bioinformatics: go.bsky.app/Ha64Gmv
r-ladies: go.bsky.app/Vgxwa2F
Reposted by Chris Clarkson
