Chrissy Wager
@chrissywager.bsky.social
TB researcher @TexasBiomed, Parker B. Francis Fellow, Dog lover, Sourdough baker
#tuberculosis #TBFighter #macrophage #innateimmunity
#tuberculosis #TBFighter #macrophage #innateimmunity
Still buzzing from the Rigor in Research Workshop at Texas Biomed! @elisabethbik.bsky.social's comments on research ethics was a powerful reminder that great science isn’t just about discovery—it’s about trust, integrity, and repeatability. 🔬 #TexasBiomed #RigorInResearch #BlueSkyScience
April 4, 2025 at 1:53 PM
Still buzzing from the Rigor in Research Workshop at Texas Biomed! @elisabethbik.bsky.social's comments on research ethics was a powerful reminder that great science isn’t just about discovery—it’s about trust, integrity, and repeatability. 🔬 #TexasBiomed #RigorInResearch #BlueSkyScience
Today is #WorldTBDay
TB is still a huge global health threat, hitting the most vulnerable communities the hardest. Treatments are tough, drug resistance is rising, and we still don’t have an effective vaccine—we need better solutions.
#TB #GlobalHealth #InfectiousDiseases #ScienceMatters
TB is still a huge global health threat, hitting the most vulnerable communities the hardest. Treatments are tough, drug resistance is rising, and we still don’t have an effective vaccine—we need better solutions.
#TB #GlobalHealth #InfectiousDiseases #ScienceMatters
March 24, 2025 at 8:06 PM
Today is #WorldTBDay
TB is still a huge global health threat, hitting the most vulnerable communities the hardest. Treatments are tough, drug resistance is rising, and we still don’t have an effective vaccine—we need better solutions.
#TB #GlobalHealth #InfectiousDiseases #ScienceMatters
TB is still a huge global health threat, hitting the most vulnerable communities the hardest. Treatments are tough, drug resistance is rising, and we still don’t have an effective vaccine—we need better solutions.
#TB #GlobalHealth #InfectiousDiseases #ScienceMatters
Reposted by Chrissy Wager
🚨1.25 million people died of TB in 2023
🚨10.8 million new cases of TB were diagnosed in 2023
🚨Multi-drug resistant TB is a public health crisis
🚨US$ 22 billion is needed annually for TB prevention, diagnosis, treatment and care, but funding is being cut.
🚨Poverty fuels TB globally
#WorldTBDay2025
🚨10.8 million new cases of TB were diagnosed in 2023
🚨Multi-drug resistant TB is a public health crisis
🚨US$ 22 billion is needed annually for TB prevention, diagnosis, treatment and care, but funding is being cut.
🚨Poverty fuels TB globally
#WorldTBDay2025
March 24, 2025 at 10:33 AM
🚨1.25 million people died of TB in 2023
🚨10.8 million new cases of TB were diagnosed in 2023
🚨Multi-drug resistant TB is a public health crisis
🚨US$ 22 billion is needed annually for TB prevention, diagnosis, treatment and care, but funding is being cut.
🚨Poverty fuels TB globally
#WorldTBDay2025
🚨10.8 million new cases of TB were diagnosed in 2023
🚨Multi-drug resistant TB is a public health crisis
🚨US$ 22 billion is needed annually for TB prevention, diagnosis, treatment and care, but funding is being cut.
🚨Poverty fuels TB globally
#WorldTBDay2025
Very excited to learn that @elisabethbik.bsky.social will be speaking at @txbiomed.bsky.social's upcoming Research Symposium! The work Dr. Bik has done to call out scientific misconduct and promote integrity is critical to advancing scientific research and gaining trust from non-scientists. 🔬🧪
March 19, 2025 at 6:15 PM
Very excited to learn that @elisabethbik.bsky.social will be speaking at @txbiomed.bsky.social's upcoming Research Symposium! The work Dr. Bik has done to call out scientific misconduct and promote integrity is critical to advancing scientific research and gaining trust from non-scientists. 🔬🧪
Reposted by Chrissy Wager
You need to read this.
I’m the Canadian who was detained by Ice for two weeks. It felt like I had been kidnapped — Guardian US
I was stuck in a freezing cell without explanation despite eventually having lawyers and media attention. Yet, compared with others, I was lucky
apple.news
March 19, 2025 at 12:32 PM
You need to read this.
Reposted by Chrissy Wager
Goodbye study sections: www.nih.gov/news-events/...
NIH centralizes peer review to improve efficiency and strengthen integrity
The proposed approach is expected to save more than $65 million annually.
www.nih.gov
March 7, 2025 at 2:32 AM
Goodbye study sections: www.nih.gov/news-events/...
Reposted by Chrissy Wager
So happy to share our latest paper on #AlveolarMacrophage responses to low-dose #LPS led by @pamelialim.bsky.social!AM #innate responses are enhanced by IFN-beta due to low c-Maf and IL-10 expression, with implications for AM responses to respiratory infections and environmental exposure. #ImmunoSky
Absence of c-Maf and IL-10 enables type I IFN enhancement of innate responses to LPS in alveolar macrophages
Abstract. Alveolar macrophages (AMs) are lung-resident myeloid cells and airway sentinels for inhaled pathogens and environmental particles. While AMs can
academic.oup.com
March 4, 2025 at 2:21 PM
So happy to share our latest paper on #AlveolarMacrophage responses to low-dose #LPS led by @pamelialim.bsky.social!AM #innate responses are enhanced by IFN-beta due to low c-Maf and IL-10 expression, with implications for AM responses to respiratory infections and environmental exposure. #ImmunoSky
Reposted by Chrissy Wager
Some good news! The final program for the inaugural #GRCBiologyofMycobacteria is up! We are also officially oversubscribed but cancellations happen... www.grc.org/biology-of-m...
2025 Biology of Mycobacteria Conference GRC
The 2025 Gordon Research Conference on Biology of Mycobacteria will be held in Pomona, California. Apply today to reserve your spot.
www.grc.org
February 27, 2025 at 12:17 AM
Some good news! The final program for the inaugural #GRCBiologyofMycobacteria is up! We are also officially oversubscribed but cancellations happen... www.grc.org/biology-of-m...
I’m devastated about layoffs of so many promising young scientists. We have a number of postdoc job openings at the Texas Biomedical Research Institute in addition to many other openings. Best of luck to those suddenly on the job market.
www.txbiomed.org/careers/
www.txbiomed.org/careers/
Careers - Texas Biomed
Join Texas Biomedical Research Institute today and enjoy making a difference in the health and wellbeing of others.
www.txbiomed.org
February 27, 2025 at 8:20 PM
I’m devastated about layoffs of so many promising young scientists. We have a number of postdoc job openings at the Texas Biomedical Research Institute in addition to many other openings. Best of luck to those suddenly on the job market.
www.txbiomed.org/careers/
www.txbiomed.org/careers/
Reposted by Chrissy Wager
The Atlantic story on the situation at NIH is sobering. We are so screwed.
www.theatlantic.com/health/archi...
www.theatlantic.com/health/archi...
Inside the Collapse at NIH
Administration officials pressured NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.
www.theatlantic.com
February 27, 2025 at 4:41 PM
The Atlantic story on the situation at NIH is sobering. We are so screwed.
www.theatlantic.com/health/archi...
www.theatlantic.com/health/archi...
Reposted by Chrissy Wager
The first review of EVERYTHING IS TUBERCULOSIS is here and it's a **star** from Kirkus. (Mild spoilers ahead.) www.kirkusreviews.com/book-reviews...
EVERYTHING IS TUBERCULOSIS | Kirkus Reviews
A YA author uses his platform to tell the story of a curable disease that kills over a million people a year.
www.kirkusreviews.com
January 8, 2025 at 9:25 PM
The first review of EVERYTHING IS TUBERCULOSIS is here and it's a **star** from Kirkus. (Mild spoilers ahead.) www.kirkusreviews.com/book-reviews...
Reposted by Chrissy Wager
🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study
Our findings propose a causal relationship between reduced IL-6 signalling and lower
risk of tuberculosis, akin to the effect seen in other IL-6 mediated diseases. This
study suggests that IL-6 antago...
www.thelancet.com
November 21, 2024 at 10:30 AM
🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
Reposted by Chrissy Wager
1/📢 In our new PREPRINT - tinyurl.com/yc6kbay9 - we estimate that 156 million people globally carry a recent, viable M. tuberculosis (Mtb) infection and are at high risk of progressing to TB disease.
Estimating the Global Burden of Viable Mycobacterium Tuberculosis Infection
Background: Estimating the proportion of individuals currently infected with Mycobacterium tuberculosis (Mtb) is key for informing global health policies. Altho
tinyurl.com
November 14, 2024 at 6:22 AM
1/📢 In our new PREPRINT - tinyurl.com/yc6kbay9 - we estimate that 156 million people globally carry a recent, viable M. tuberculosis (Mtb) infection and are at high risk of progressing to TB disease.