chrisaufeggen.bsky.social
@chrisaufeggen.bsky.social
Reposted
Larry and David Ellison didn’t always have a close relationship, but now the father and son have formed an unusual tag team in their pursuit of major media deals. They bought Paramount this summer, and now they are hunting Warner Bros. Discovery with a $108 billion hostile bid.
A Father and Son’s $108 Billion Hostile Bid for Warner Bros. Discovery
Larry and David Ellison didn’t always have a close relationship. Now they’re one of the most intriguing partnerships in business.
nyti.ms
December 24, 2025 at 9:00 PM
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Three-Dimensional Epigenome Roadmap of Human B-cell Differentiation Uncovers Mechanisms of Humoral Immunity and Oncogenesis https://www.biorxiv.org/content/10.64898/2025.12.22.695871v1
December 24, 2025 at 9:32 PM
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🎉 5,000+ genome assemblies sequenced!
EBP affiliates are building momentum, and we’re already looking ahead to the next genome sequencing milestone on the road to 2026.
Congratulations to everyone who worked together to make this happen. Happy holidays and a happy New Year! ✨🧬
December 24, 2025 at 11:45 PM
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US-Außenminister Marco Rubio hat heute Sanktionen gegen fünf Personen eines 'weltweiten Zensurkomplexes' angekündigt. Darunter @thierrybreton.bsky.social, ehemaliger EU-Digitalkommissar. Während seiner Amtszeit wurde der #DigitalServicesAct verabschiedet.

www.state.gov/releases/off...
Announcement of Actions to Combat the Global Censorship-Industrial Complex - United States Department of State
The State Department is taking decisive action against five individuals who have led organized efforts to coerce American platforms to censor, demonetize, and suppress American viewpoints they oppose....
www.state.gov
December 23, 2025 at 10:32 PM
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This trio 🤩
December 23, 2025 at 4:38 AM
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Brilliant. 10/10. No notes.
June 27, 2025 at 2:10 AM
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Heavily armed paramilitary forces stormed a local San Diego restaurant today, deployed stun grenades against a crowd of onlookers, and kidnapped a handful of kitchen workers.
May 31, 2025 at 5:33 AM
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Two groundbreaking open-access papers on integrated atlases of human #organoids are out: researchers at #Roche |s Institute of Human Biology(#teamIHB),
@ethz.ch, @www.helmholtz-munich.de, and collaborators have built detailed atlases of #brain, #gut, and #lung organoids > u.ethz.ch/6Rjq
May 19, 2025 at 2:14 PM
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Arthur continues, showcasing how long-read sequencing discovered a novel fusion in an ovarian cancer patient—one that short-read methods miscalled as simple overexpression of the 3' fusion partner. #AACR25 #PacBio 
April 28, 2025 at 6:20 PM
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Arthur Dondi, PhD, from ETH Zürich is now presenting at #AACR25!

He shares how cancer cells express the IGF1 class II isoform, while normal cells express class I. The secreted class II promotes growth of neighboring cells—an important distinction revealed by long-read sequencing. #PacBio
April 28, 2025 at 6:10 PM
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We’ve touched down in Chicago for #AACR25!  

Join us at booth #1042 to explore how #PacBio long-read sequencing is revolutionizing cancer research—helping scientists uncover critical variants that others miss.  

🧬 Discover more: bit.ly/42A3PkD
April 26, 2025 at 5:39 PM
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The CDC latest genomic surveillance of SARS-CoV-2 shows the dominant LP.8.1 variant accounts for ~70% of cases.
Good that no other new variant has emerged so far and that the tracking here continues.
covid.cdc.gov/covid-data-t...
April 25, 2025 at 2:52 PM
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So cool!
April 27, 2025 at 3:31 AM
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10/10 "Our study demonstrates that influenza A virus is a transboundary pathogen that requires coordination across regulatory agencies & between animal & public health organisations to improve the health of hosts & reduce pandemic risk," they urgently conclude.

www.science.org/doi/10.1126/...
Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle in the United States
Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagg...
www.science.org
April 26, 2025 at 8:00 PM
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Long-read sequencing of large pedigrees is an ideal way to map all classes of denovo mutations! A collaboration between University of Utah, University of Washington, and PacBio. Glad to be a part of this project 👏

www.nature.com/articles/s41...
Human de novo mutation rates from a four-generation pedigree reference - Nature
Analysis of more than 95% of each diploid human genome of a four-generation, twenty-eight-member family using five complementary short-read and long-read sequencing technologies provides a truth set t...
www.nature.com
April 23, 2025 at 4:11 PM
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👇🏻👇🏻
The cover of this week’s Economist.
April 24, 2025 at 5:23 PM
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April 25th is #DNADay — but really, every day is DNA Day at Whitehead Institute. For the curious-minded, especially students and teachers, here is a collection of stories focused on this versatile structure that provides the blueprint for life: wi.mit.edu/bionook/gene...
April 25, 2025 at 5:58 PM
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The impact of long-read sequencing on human population-scale genomics genome.cshlp.org/content/35/4... 🧬🖥️🧪
April 21, 2025 at 6:30 PM
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Das beste Bild des Tages. #NieWieder ❗️
January 25, 2025 at 4:56 PM
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Damning data.
This is bad for life as we know it…
NEW: 2024 has just been confirmed as the warmest year on record, and the first to breach the 1.5C threshold.

We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940.

2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.
January 10, 2025 at 3:32 PM