Jon Davidow
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choisi.bsky.social
Jon Davidow
@choisi.bsky.social
PGY 4 Neurology, interested in #consciousness #coma and #AI in #Neurocriticalcare
Reposted by Jon Davidow
The Erosion of Harm Reduction | New England Journal of Medicine www.nejm.org/doi/full/10....
The Erosion of Harm Reduction | NEJM
The U.S. administration has continuously chipped away at public health interventions addressing substance use disorders and the opioid crisis, including vital harm-reduction activities.
www.nejm.org
November 8, 2025 at 1:29 PM
Reposted by Jon Davidow
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans | PLOS Biology journals.plos.org/plosbiology/...
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
journals.plos.org
October 21, 2025 at 10:11 PM
Reposted by Jon Davidow
Today, a team of scientists led by Jordan DeKraker, Boris Bernhardt and Alan Evans published HippoMaps, an #openaccess toolbox and online data warehouse for the mapping and contextualization of subregional hippocampal data in the human brain.

🧠 rdcu.be/eI1ye
October 1, 2025 at 2:31 PM
Lots of interesting implications…
Intervening on a central node in a network likely does little given that its connected neighbors will "flip it back" immediately. Happy to see this position supported now.

"Change is most likely [..] if it spreads first among relatively poorly connected nodes."

www.nature.com/articles/s41...
Transformation starts at the periphery of networks where pushback is less - Scientific Reports
Scientific Reports - Transformation starts at the periphery of networks where pushback is less
www.nature.com
September 29, 2025 at 10:21 AM
Reposted by Jon Davidow
Switching from 1% to 2% propofol in ICU sedation cut greenhouse gas emissions, waste, and costs, with savings equal to over seven Paris–New York flights annually, showing concentration adjustment as a path to greener critical care. zurl.co/DHWbi
September 21, 2025 at 8:00 AM
Extremely inspiring start to #NCS2025 with a presentation of the RECOVER program and consortium, a beautiful multi-d approach to improve the clinical care of people in coma www.med.upenn.edu/recover-prog...
RECOVER Program Overview | Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program | Perelman School of Medicine at the University of Pennsylvania
Information about the Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program at the University of Pennsylvania.
www.med.upenn.edu
September 18, 2025 at 11:14 PM
Interesting work helping to move from the subjective to the objective in psychedelic science.
September 17, 2025 at 1:07 PM
Reposted by Jon Davidow
generalized convulsive status epilepticus update:

feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇

thoughts/opinions?

rationale explained here: pubmed.ncbi.nlm.nih.gov/36609129/

evidence is accumulating eg, pubmed.ncbi.nlm.nih.gov/37610640/ #EMIMCC
April 16, 2025 at 2:18 PM
www.cell.com/cell/fulltex...

Lots of serotonergic neuroprotectantive agents to explore.
Serotonin reduction in post-acute sequelae of viral infection
Post-viral syndromes are associated with serotonin reduction, which may contribute to the neurological and cognitive symptoms seen in individuals with Long COVID.
www.cell.com
November 26, 2024 at 8:13 PM