Jon Davidow
@choisi.bsky.social
PGY 4 Neurology, interested in #consciousness #coma and #AI in #Neurocriticalcare
Reposted by Jon Davidow
The Erosion of Harm Reduction | New England Journal of Medicine www.nejm.org/doi/full/10....
The Erosion of Harm Reduction | NEJM
The U.S. administration has continuously chipped away at public health interventions
addressing substance use disorders and the opioid crisis, including vital harm-reduction
activities.
www.nejm.org
November 8, 2025 at 1:29 PM
The Erosion of Harm Reduction | New England Journal of Medicine www.nejm.org/doi/full/10....
Reposted by Jon Davidow
Reposted by Jon Davidow
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans | PLOS Biology journals.plos.org/plosbiology/...
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
journals.plos.org
October 21, 2025 at 10:11 PM
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans | PLOS Biology journals.plos.org/plosbiology/...
Reposted by Jon Davidow
Today, a team of scientists led by Jordan DeKraker, Boris Bernhardt and Alan Evans published HippoMaps, an #openaccess toolbox and online data warehouse for the mapping and contextualization of subregional hippocampal data in the human brain.
🧠 rdcu.be/eI1ye
🧠 rdcu.be/eI1ye
October 1, 2025 at 2:31 PM
Today, a team of scientists led by Jordan DeKraker, Boris Bernhardt and Alan Evans published HippoMaps, an #openaccess toolbox and online data warehouse for the mapping and contextualization of subregional hippocampal data in the human brain.
🧠 rdcu.be/eI1ye
🧠 rdcu.be/eI1ye
Lots of interesting implications…
Intervening on a central node in a network likely does little given that its connected neighbors will "flip it back" immediately. Happy to see this position supported now.
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
Transformation starts at the periphery of networks where pushback is less - Scientific Reports
Scientific Reports - Transformation starts at the periphery of networks where pushback is less
www.nature.com
September 29, 2025 at 10:21 AM
Lots of interesting implications…
Reposted by Jon Davidow
Switching from 1% to 2% propofol in ICU sedation cut greenhouse gas emissions, waste, and costs, with savings equal to over seven Paris–New York flights annually, showing concentration adjustment as a path to greener critical care. zurl.co/DHWbi
September 21, 2025 at 8:00 AM
Switching from 1% to 2% propofol in ICU sedation cut greenhouse gas emissions, waste, and costs, with savings equal to over seven Paris–New York flights annually, showing concentration adjustment as a path to greener critical care. zurl.co/DHWbi
Extremely inspiring start to #NCS2025 with a presentation of the RECOVER program and consortium, a beautiful multi-d approach to improve the clinical care of people in coma www.med.upenn.edu/recover-prog...
RECOVER Program Overview | Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program | Perelman School of Medicine at the University of Pennsylvania
Information about the Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program at the University of Pennsylvania.
www.med.upenn.edu
September 18, 2025 at 11:14 PM
Extremely inspiring start to #NCS2025 with a presentation of the RECOVER program and consortium, a beautiful multi-d approach to improve the clinical care of people in coma www.med.upenn.edu/recover-prog...
Interesting work helping to move from the subjective to the objective in psychedelic science.
Psychedelic neuroplasticity of cortical neurons lacking 5-HT2A receptors www.nature.com/articles/s41...
Psychedelic neuroplasticity of cortical neurons lacking 5-HT2A receptors - Molecular Psychiatry
Molecular Psychiatry - Psychedelic neuroplasticity of cortical neurons lacking 5-HT2A receptors
www.nature.com
September 17, 2025 at 1:07 PM
Interesting work helping to move from the subjective to the objective in psychedelic science.
Practice changing systematic review and meta analysis, no evidence of symptomatic ICH with early DOAC: www.thelancet.com/journals/lan...
Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised contr...
For people with acute ischaemic stroke and atrial fibrillation, early DOAC initiation
(within 4 days) reduced the risk of the composite outcome of recurrent ischaemic stroke,
symptomatic intracerebral...
www.thelancet.com
July 6, 2025 at 9:57 AM
Practice changing systematic review and meta analysis, no evidence of symptomatic ICH with early DOAC: www.thelancet.com/journals/lan...
Reposted by Jon Davidow
ICYMI: New online! Autoimmune encephalitis-associated epilepsy
Autoimmune encephalitis-associated epilepsy
Nature Reviews Neurology, Published online: 02 May 2025; doi:10.1038/s41582-025-01089-4In this Perspective, the authors provide a detailed description of rare autoimmune encephalitic conditions that present with recurrent seizures that are resistant to immunotherapy, grouped under the term autoimmune encephalitis-associated epilepsy. The article considers the clinical characteristics and pathophysiological mechanisms of these conditions, alongside current knowledge of treatment and outcomes.
bit.ly
May 4, 2025 at 7:41 AM
ICYMI: New online! Autoimmune encephalitis-associated epilepsy
Reposted by Jon Davidow
generalized convulsive status epilepticus update:
feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇
thoughts/opinions?
rationale explained here: pubmed.ncbi.nlm.nih.gov/36609129/
evidence is accumulating eg, pubmed.ncbi.nlm.nih.gov/37610640/ #EMIMCC
feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇
thoughts/opinions?
rationale explained here: pubmed.ncbi.nlm.nih.gov/36609129/
evidence is accumulating eg, pubmed.ncbi.nlm.nih.gov/37610640/ #EMIMCC
April 16, 2025 at 2:18 PM
generalized convulsive status epilepticus update:
feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇
thoughts/opinions?
rationale explained here: pubmed.ncbi.nlm.nih.gov/36609129/
evidence is accumulating eg, pubmed.ncbi.nlm.nih.gov/37610640/ #EMIMCC
feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇
thoughts/opinions?
rationale explained here: pubmed.ncbi.nlm.nih.gov/36609129/
evidence is accumulating eg, pubmed.ncbi.nlm.nih.gov/37610640/ #EMIMCC
Proud to share cases which might help to change the outcome for others bmcneurol.biomedcentral.com/articles/10....
Delayed diagnosis of basilar artery occlusion in a 28-year-old postpartum woman - BMC Neurology
Background Basilar artery strokes, which are often challenging to diagnose due to their diverse symptoms and uncommon occurrence, demand timely identification to mitigate severe consequences. Case pre...
bmcneurol.biomedcentral.com
December 4, 2024 at 11:05 AM
Proud to share cases which might help to change the outcome for others bmcneurol.biomedcentral.com/articles/10....