Ching-Shin Huang
@chingshinhuang.bsky.social
Structural biologist. Open science supporter. Opinions are my own.
Working with @astbury-bsl.bsky.social, we report cryo-EM structures of CD163 in its apo state and in complex with haptoglobin–hemoglobin (HpHb), and propose a framework of how CD163-mediated endocytosis clears different isoforms of HpHb. Please check it out on @plosbiology.org!
The #macrophage CD163 receptor clears free #hemoglobin in the bloodstream by binding the HpHb complex. The #cryoEM structure of CD163-HpHb complex, by @chingshinhuang.bsky.social &co, reveals how CD163-mediated endocytosis clears different HpHb isoforms @plosbiology.org 🧪 plos.io/4nNBbGI
July 19, 2025 at 12:36 PM
Working with @astbury-bsl.bsky.social, we report cryo-EM structures of CD163 in its apo state and in complex with haptoglobin–hemoglobin (HpHb), and propose a framework of how CD163-mediated endocytosis clears different isoforms of HpHb. Please check it out on @plosbiology.org!
Reposted by Ching-Shin Huang
Really pleased to share this story in collaboration with our fantastic industry partners @chingshinhuang.bsky.social !
Structural elucidation of the haptoglobin-hemoglobin clearance mechanism by macrophage scavenger receptor CD163 https://www.biorxiv.org/content/10.1101/2025.02.14.638171v1
February 20, 2025 at 7:04 PM
Really pleased to share this story in collaboration with our fantastic industry partners @chingshinhuang.bsky.social !
Reposted by Ching-Shin Huang
December 16, 2024 at 12:04 PM
Reposted by Ching-Shin Huang
Three BioML starter packs now!
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
December 3, 2024 at 3:27 AM
Three BioML starter packs now!
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
Reposted by Ching-Shin Huang
Been thinking about creating a collection of good protein structure figures, as inspiration for my own work.
#1 www.nature.com/articles/s41...
#1 www.nature.com/articles/s41...
March 3, 2024 at 8:37 AM
Been thinking about creating a collection of good protein structure figures, as inspiration for my own work.
#1 www.nature.com/articles/s41...
#1 www.nature.com/articles/s41...
Reposted by Ching-Shin Huang
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Reposted by Ching-Shin Huang
Here is a brief summary of academic journals and news account.
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
November 30, 2024 at 3:21 AM
Here is a brief summary of academic journals and news account.
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Reposted by Ching-Shin Huang
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
November 17, 2024 at 6:48 PM
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
Reposted by Ching-Shin Huang
So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬
go.bsky.app/HByHiW6
go.bsky.app/HByHiW6
November 17, 2024 at 11:07 AM
So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬
go.bsky.app/HByHiW6
go.bsky.app/HByHiW6
Reposted by Ching-Shin Huang
So many people added to pack 1 this weekend we had to make pack 2. Makes sure you refresh for followers on pack one to see them all!
🧶🧬
go.bsky.app/DDetSBp
🧶🧬
go.bsky.app/DDetSBp
November 17, 2024 at 11:37 AM
So many people added to pack 1 this weekend we had to make pack 2. Makes sure you refresh for followers on pack one to see them all!
🧶🧬
go.bsky.app/DDetSBp
🧶🧬
go.bsky.app/DDetSBp