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cheesan-tong.bsky.social
73
@cheesan-tong.bsky.social
| cell biologist turned public school teacher | i teach biology + chemistry in singapore 🇸🇬 | honorary yale cell biology @wumin-lab.bsky.social & former nus biological sciences | lipid metabolism | patterns | chaos | wave | oscillations |
Reposted by 73
February 27, 2025 at 2:43 AM
Reposted by 73
In vitro reconstitution by Peter Bieling, William Bement and collaborators reveals mechanistic principles of Rho GTPase activity patterning at cellular membranes, and stage-specific roles of regulators
www.embopress.org/doi/full/10....
April 1, 2025 at 8:01 AM
Reposted by 73
Amazing microscopy from Bewersdorf/Rothman groups shows golgins in a striking four-layered structure at the Golgi rim. Biochemical reconstitution shows long filaments. Does a Golgi stack form due to golgin filament properties rather than dedicated stacking proteins?
www.biorxiv.org/content/10.1...
March 29, 2025 at 9:02 PM
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The Golgi Rim is a Precise Tetraplex of Golgin Proteins that Can Self-Assemble into Filamentous Bands https://www.biorxiv.org/content/10.1101/2025.03.27.645134v1
March 28, 2025 at 1:30 PM
Reposted by 73
Pretty amazing (but v. technical) abstract. Onto my reading list.
STIM1 and Endoplasmic Reticulum-Plasma Membrane Contact Sites Oscillate Independently of Calcium-Induced Calcium Release https://www.biorxiv.org/content/10.1101/2025.03.16.643575v1
March 18, 2025 at 6:05 AM
can you see the blinks in the oscillations here? really subtle but we think they're real!
March 18, 2025 at 2:27 PM
Reposted by 73
Incredible new work from Yongdeng Zhang demonstrating live 4Pi SIM--and in two colors! www.nature.com/articles/s41...
Elucidating subcellular architecture and dynamics at isotropic 100-nm resolution with 4Pi-SIM - Nature Methods
The 4Pi-SIM microscope combines the benefits of structured illumination microscopy with 4Pi geometry for improved axial resolution, offering isotropic, multicolor super-resolution imaging of dynamic p...
www.nature.com
December 24, 2024 at 1:47 PM
Reposted by 73
Please visit our formal postgrad Jerry Chua's poster if you will be at ASCB. #CellBio2024

When Jerry started to work on actin, my view was, what can you possibly learn about actin that is new 🤭. I am glad that he ignored me and followed his heart ~ @xianglejerry.bsky.social
Look at these distinct clusters exhibited by N-WASP and Arp2/3 ! Is branched #actin polymerization the sole driving force for nucleating cortical actin waves? Cross-talks within the actin network can be messy, so how can we study such complexities? #CellBio2024 @ascbiology.bsky.social
December 2, 2024 at 11:11 PM