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cellbiol-mrclmb.bsky.social
MRC-LMB Cell Biology Division
@cellbiol-mrclmb.bsky.social
3.8K followers 1.6K following 36 posts
Our aim is to understand the biological organisation of cells and organisms, and the molecular mechanisms underlying their function. https://www2.mrc-lmb.cam.ac.uk/research/cell-biology/
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Reposted by MRC-LMB Cell Biology Division
sokrypton.org
A few py2Dmol updates 🧬

py2dmol.solab.org
Integration with AlphaFoldDB (will auto fetch results). Drag and drop results from AF3-server or ColabFold for interactive experience! (1/4)
November 19, 2025 at 8:15 AM
Reposted by MRC-LMB Cell Biology Division
biorxiv-cellbio.bsky.social
DETERMINATION OF THE TRANSBILAYER DISTRIBUTION OF PLASMA MEMBRANE CHOLESTEROL https://www.biorxiv.org/content/10.1101/2025.11.13.687888v1
November 14, 2025 at 10:30 PM
Reposted by MRC-LMB Cell Biology Division
pedromartinezserra.bsky.social
Yesterday, we lost a giant of twentieth century genetics, Antonio Garcia Bellido. His legacy will remain deeply rooted in the history of biology. Rest in peace.
November 11, 2025 at 9:47 AM
Reposted by MRC-LMB Cell Biology Division
deglushk.bsky.social
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Reposted by MRC-LMB Cell Biology Division
jcb.org
Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...
November 4, 2025 at 5:30 PM
Reposted by MRC-LMB Cell Biology Division
seemagrewal.bsky.social
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella

journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
Reposted by MRC-LMB Cell Biology Division
nccomfort.bsky.social
Look what the dog fetched up! @matthewcobb.bsky.social’s new biography of Francis Crick.

Folks, it’s like no other Crick biog. Full of new research, fresh insights, juicy stories, & it’s a romp.

Having watched this develop from the larval stage, it’s a thrill to hear it thunk! on my table
October 29, 2025 at 2:58 AM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
Congratulations to the 2025 recipients of the Perutz Student Prize and the Joan Steitz Postdoc Prize: Claudia De Miguel, @lucaschwarz.bsky.social, Tom Dendooven, Sofia Lövestam, Katerina Naydenva & Tomke Stürner.

Find out why they won here: www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...

#LMBNews 👏
LMB prize winners with certificates in the Max Perutz Lecture Theatre with clapping audience
October 24, 2025 at 8:52 AM
Reposted by MRC-LMB Cell Biology Division
ishier.bsky.social
New preprint from Sean Munro @cellbiol-mrclmb.bsky.social! Golgi tether p115 directly binds Sec16A at ER exit sites. Mutations blocking this binding reduce secretion. A rich new mechanistic insight into physical coupling of ERES–ERGIC/Golgi.
www.biorxiv.org/content/10.1...
The Golgi vesicle tether p115/USO1 can bind directly to the ER exit site organiser Sec16A
Newly-made secretory and membrane proteins exit the endoplasmic reticulum (ER) in COPII vesicles that form at specialised ER exit sites. These exit sites are typically near to the early Golgi compartm...
www.biorxiv.org
October 17, 2025 at 7:36 AM
Reposted by MRC-LMB Cell Biology Division
lizmillercu.bsky.social
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.

www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - MCDB - UOD2016
Closing date: Thursday 6 November 2025, 23:59
www.dundee.ac.uk
October 15, 2025 at 12:53 PM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
#ICYMI, @jefferis.bsky.social’s group recently published the first complete connectome of an entire male Drosophila central nervous system with @hhmijanelia.bsky.social and other collaborators.
Read more about the work here: www.janelia.org/project-team...
#LMBintheNews 🧪🪰
October 15, 2025 at 3:13 PM
Reposted by MRC-LMB Cell Biology Division
biologists.bsky.social
1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.
Poster of the 100-year history of The Company of Biologists.
October 15, 2025 at 8:04 AM
Reposted by MRC-LMB Cell Biology Division
aemonten.bsky.social
PREACH!

www.nature.com/articles/s41...
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
www.nature.com
October 10, 2025 at 8:48 PM
Reposted by MRC-LMB Cell Biology Division
briggsgroup.bsky.social
The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...
The mechanistic basis of cargo selection during Golgi maturation
Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.
www.science.org
October 6, 2025 at 11:39 AM
Reposted by MRC-LMB Cell Biology Division
seemagrewal.bsky.social
So sad to hear the news - John truly was an inspiration to so many, and one of a kind.

www.cam.ac.uk/research/new...
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
October 7, 2025 at 4:02 PM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
The LMB is delighted to announce Madeline Lancaster as Joint Head of @cellbiol-mrclmb.bsky.social and Julian Sale as Joint Head of the PNAC Division!
Read more below.
Madeline (@lancasterlab.bsky.social): www2.mrc-lmb.cam.ac.uk/madeline-lan...
Julian: www2.mrc-lmb.cam.ac.uk/julian-sale-...
#LMBNews
Madeline Lancaster and Julian Sale
October 6, 2025 at 9:00 AM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
Providing order amongst constant traffic: #LMBResearch from Sean Munro (@cellbiol-mrclmb.bsky.social) with John Briggs (@mpibiochem.bsky.social) reveals how GOLPH3 allows COPI vesicles to distinguish between Golgi residents & ER-bound proteins.
Read more: www2.mrc-lmb.cam.ac.uk/protein-sort...
October 6, 2025 at 8:07 AM
Reposted by MRC-LMB Cell Biology Division
natrevmcb.nature.com
ICYMI: New Online! The advent of confocal laser scanning microscopy in biological research
The advent of confocal laser scanning microscopy in biological research
Nature Reviews Molecular Cell Biology, Published online: 01 October 2025; doi:10.1038/s41580-025-00905-5The advent of laser-scanning confocal microscopy revolutionized cell biology, offering unprecedented resolution and depth and enabling scientists to visualize cellular structures in 3D.
bit.ly
October 4, 2025 at 12:05 PM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
Excellent opportunity for an enthusiastic #postdoc to join Kate McDole in @cellbiol-mrclmb.bsky.social, using interdisciplinary approaches to investigate tissue formation during early organogenesis in mouse embryos.
More info: www.nature.com/naturecareer...
Closes 20 OCT
#ScienceJobs #PostdocJobs
October 2, 2025 at 8:53 AM
Reposted by MRC-LMB Cell Biology Division
cahirokane.bsky.social
When BCE (before the confocal era) turned into CE (confocal era) - 1987
October 1, 2025 at 5:09 PM
Reposted by MRC-LMB Cell Biology Division
embo.org
"EMBO support is very important – not only for the young scientists here in #Hungary, but also the more established scientists, as well as the connection you get with EMBO and with EMBO-related institutes,” says Rita Sinka, former EMBO Installation Grantee: www.embo.org/people/the-i... #research 🧪
The importance of basic research – People – EMBO
Meet Rita Sinka, associate professor and head of the Department of Genetics at the University of Szeged, and former EMBO Installation Grantee
www.embo.org
October 1, 2025 at 9:43 AM
Reposted by MRC-LMB Cell Biology Division
lisaheinke.bsky.social
Many thanks to Sean (@cellbiol-mrclmb.bsky.social) for writing this Journal Club for us!
October 1, 2025 at 12:14 PM
Reposted by MRC-LMB Cell Biology Division
johanduchene.bsky.social
⚠️ Half of commercial antibodies miss their target!
So how do you pick the right one for your experiment?

Here’s the solution 👉
Antibody characterization data (all tested in KO cells) are now available at:
🔗 onlygoodantibodies.co.uk

Tested by @ycharos.bsky.social & @oga-community.bsky.social
OGA - Only Good Antibodies Community
onlygoodantibodies.co.uk
September 29, 2025 at 6:34 PM
Reposted by MRC-LMB Cell Biology Division
mrclmb.bsky.social
Calling all prospective PhD students! Why not consider the LMB for your PhD?
Applications are now open!
www2.mrc-lmb.cam.ac.uk/students/int...
General deadline: 2nd DEC
US Gates Scholarship deadline: 15th OCT
Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025
September 22, 2025 at 3:30 PM
Reposted by MRC-LMB Cell Biology Division
matthewcobb.bsky.social
And here we are. Another damn’d thick, square book. A real wrist-sprainer. UK edition (pictured) has endpapers showing Crick and Brenner’s blackboard and colour plates. Both U.K. and US editions have sections heralded by a double page photo as here. Loads of illustrations. Out in November!
Cover and spine of CRICK, my biography of Francis Crick Endpapers and inside flap of book Double page photo of Crick at blackboard with section title The Central Problem Colour plate showing Crick at Cold Spring Harbor in 1954.
September 26, 2025 at 9:36 AM