Carolina Sanchez-Rocha
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caro-rocha.bsky.social
Carolina Sanchez-Rocha
@caro-rocha.bsky.social
Postdoc at @Weizmann Institute in Naama Barkai's lab 🧪🧬 | Structural biologist | Evolutionary biologist 🌳🪸🦠 | Art lover 🎨
Reposted by Carolina Sanchez-Rocha
The next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven)
🗓️ November 11th, 5pm CET

Registration is now open: tinyurl.com/prose-seminar2
Please share!
October 28, 2025 at 12:53 PM
Reposted by Carolina Sanchez-Rocha
The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU):

Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t”
Date: October 14th, 5 pm CET
Registration link: tinyurl.com/prose-seminar2
October 6, 2025 at 7:22 AM
Reposted by Carolina Sanchez-Rocha
Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪
It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas

doi.org/10.1093/gbe/...
Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record
Abstract. Protein folds are structural units defined by the number, type, arrangement, and orientation of their core secondary structural elements. The uni
doi.org
September 15, 2025 at 7:52 AM
Reposted by Carolina Sanchez-Rocha
How does catalysis emerge from non-catalytic domains?

In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead.

A striking case of catalysis evolving from binding.
October 8, 2025 at 2:32 PM
🌍ProSE Online Talk
📅 Tue Sep 9 | 🕔 5pm CET

How does protein sequence → structure → function really work?
Prof. Nir Ben-Tal will show how AI (CLSS) is reshaping our view of the protein universe and uncovering hidden evolutionary design.

🚀 Don’t miss this!

Registration: tinyurl.com/prose-seminar2
September 7, 2025 at 10:29 AM
Reposted by Carolina Sanchez-Rocha
The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space".
Date: September 9
Time: 5pm CET
Register here: tinyurl.com/prose-seminar2

Please share!
🧪 #mevosky
September 2, 2025 at 1:09 PM
Reposted by Carolina Sanchez-Rocha
Join us for the next ProSE Seminar!
We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients"
Date: June 10
Time: 4PM CET
Register here: tinyurl.com/prose-seminar2
Please share!
🧪 #MEvoSky
May 29, 2025 at 3:16 PM
Reposted by Carolina Sanchez-Rocha
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 1, 2025 at 7:32 AM
🚨 Unravel BILLIONS of years of protein evolution! 🚨

How did protein structures emerge and evolve over deep time?
Join @zachary-ardern in the next ProSE Seminar!

📅 March 11, 3PM GMT
🔗 tinyurl.com/prose-seminar2

#ProteinEvolution #StructuralBiology
February 25, 2025 at 9:55 AM
🧬 New research reveals that
encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These **alternative proteoforms** expand protein function bypassing genetic constraints.

🔗 Check it!:
www.biorxiv.org/content/10.1...

#Proteomics #CentralDogma
#Translation
Encoded and non-genetic alternative protein variants expand human functional proteome
Each stage of the Central Dogma contributes to proteome diversity through mechanisms such as heterozygosity, somatic mutations, transcriptional errors, and translational errors. As a result, a diverse...
www.biorxiv.org
February 18, 2025 at 9:09 PM
Reposted by Carolina Sanchez-Rocha
Bluesky
a.bsky.social
January 24, 2025 at 8:43 AM
Reposted by Carolina Sanchez-Rocha
The ProSE seminar series is organised by @claudiaalcar.bsky.social @hassanzaman.bsky.social
@lacholt.bsky.social
@caro-rocha.bsky.social
& me - do reach out with any questions or suggestions!
Bluesky
a.bsky.social
January 24, 2025 at 9:02 AM
New seminar series! Join us to explore how protein structures evolved!
Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫
ProSE launches one day before Darwin's day!
📅 Feb 11, 3PM GMT
🔗https://tinyurl.com/prose-seminar1
February 3, 2025 at 5:01 PM
Reposted by Carolina Sanchez-Rocha
Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪

Next up: Andrei Lupas
“Highly repetitive genomic ORFs: a source of new fibrous proteins?”
11th February | 3 PM GMT
🔗 Register here: tinyurl.com/prose-seminar1
January 29, 2025 at 9:44 AM
Reposted by Carolina Sanchez-Rocha
January 31, 2025 at 11:41 AM