Brian Sweis
@brianmsweis.bsky.social
MD, PhD | psychiatry | neuroscience | neuroeconomics | neuromodulation | assistant professor | residency program training director @MountSinaiPsych @SinaiBrain 🧠
Pinned
For those heading to #SfN25, come check out our posters on Saturday Afternoon! The lab is growing & expanding in several new directions & collabs #neuroeconomics 🧠🐭🧠 @sinaibrain.bsky.social @sinaiccp.bsky.social @sfn.org @socforneuroecon.bsky.social @bwfund.bsky.social @animalsocaging.bsky.social
Reposted by Brian Sweis
Our Behavioural Brain Research special issue on Ultrasonic Communication in Rodents is growing, rapidly – and actually a lot faster than I manage to post about it. Nine new manuscripts got accepted since my last post. Quite impressive work. Check it out:
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
November 6, 2025 at 12:53 PM
Our Behavioural Brain Research special issue on Ultrasonic Communication in Rodents is growing, rapidly – and actually a lot faster than I manage to post about it. Nine new manuscripts got accepted since my last post. Quite impressive work. Check it out:
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Reposted by Brian Sweis
📣We are hiring! 📣
Join us as a Postdoctoral Researcher to study brain–body interactions uncovering how neural and physiological systems regulate behavior and energy metabolism under stress!
Details are below:
📩 abha.rajbhandari@mssm.edu 🔗 careers.mountsinai.org/jobs/3032214
Details are below:
📩 abha.rajbhandari@mssm.edu 🔗 careers.mountsinai.org/jobs/3032214
Postdoctoral Fellow-MSH-13400-363 in New York, NY | Mount Sinai Health Systems
Mount Sinai is hiring a Postdoctoral Fellow-MSH-13400-363 in New York, NY. Review all of the job details and apply today!
careers.mountsinai.org
October 29, 2025 at 2:22 PM
📣We are hiring! 📣
Join us as a Postdoctoral Researcher to study brain–body interactions uncovering how neural and physiological systems regulate behavior and energy metabolism under stress!
Details are below:
📩 abha.rajbhandari@mssm.edu 🔗 careers.mountsinai.org/jobs/3032214
Details are below:
📩 abha.rajbhandari@mssm.edu 🔗 careers.mountsinai.org/jobs/3032214
For those heading to #SfN25, come check out our posters on Saturday Afternoon! The lab is growing & expanding in several new directions & collabs #neuroeconomics 🧠🐭🧠 @sinaibrain.bsky.social @sinaiccp.bsky.social @sfn.org @socforneuroecon.bsky.social @bwfund.bsky.social @animalsocaging.bsky.social
October 29, 2025 at 11:27 PM
For those heading to #SfN25, come check out our posters on Saturday Afternoon! The lab is growing & expanding in several new directions & collabs #neuroeconomics 🧠🐭🧠 @sinaibrain.bsky.social @sinaiccp.bsky.social @sfn.org @socforneuroecon.bsky.social @bwfund.bsky.social @animalsocaging.bsky.social
Reposted by Brian Sweis
"The way forward has become very clear"- Dr. Brendan G. Carr
A HUGE CONGRATULATIONS to @ericjnestler.bsky.social named Anne & Joel Ehrenkranz Dean of the Icahn School of Medicine. We’re thrilled about the exciting new direction Icahn Mount Sinai will take under Dr. Nestler's visionary leadership!
A HUGE CONGRATULATIONS to @ericjnestler.bsky.social named Anne & Joel Ehrenkranz Dean of the Icahn School of Medicine. We’re thrilled about the exciting new direction Icahn Mount Sinai will take under Dr. Nestler's visionary leadership!
October 23, 2025 at 9:39 PM
"The way forward has become very clear"- Dr. Brendan G. Carr
A HUGE CONGRATULATIONS to @ericjnestler.bsky.social named Anne & Joel Ehrenkranz Dean of the Icahn School of Medicine. We’re thrilled about the exciting new direction Icahn Mount Sinai will take under Dr. Nestler's visionary leadership!
A HUGE CONGRATULATIONS to @ericjnestler.bsky.social named Anne & Joel Ehrenkranz Dean of the Icahn School of Medicine. We’re thrilled about the exciting new direction Icahn Mount Sinai will take under Dr. Nestler's visionary leadership!
Reposted by Brian Sweis
When I moved to BCM, an extremely talented movement disorders neurologist, Nora Vanegas Arroyave, reached out to discuss brain circuits responsible for non-motor deficits in Parkinson's Disease. I have learned so much from her and from this collaboration. One paper out, more to come!
Apathy, effort-based decisions and brain integrity in Alzheimer’s and Parkinson’s diseases
Morris et al. identify a common behavioural signature of apathy in Alzheimer’s and Parkinson’s disease: a decision bias towards rejecting the option to exe
academic.oup.com
October 21, 2025 at 2:51 PM
When I moved to BCM, an extremely talented movement disorders neurologist, Nora Vanegas Arroyave, reached out to discuss brain circuits responsible for non-motor deficits in Parkinson's Disease. I have learned so much from her and from this collaboration. One paper out, more to come!
Reposted by Brian Sweis
We are also considering applications from undergraduate students and Master's students in the local New York City area!
Please check out our website for more information on how to become involved: sinclaboratory.com/apply
Please check out our website for more information on how to become involved: sinclaboratory.com/apply
Apply
SOCIAL INTERACTION &<br>NEURAL COMPUTATION LAB. The SINC Lab examines the neural and computational basis of social cognition and interaction. We are particularly interested in understanding how social...
sinclaboratory.com
September 22, 2025 at 6:17 PM
We are also considering applications from undergraduate students and Master's students in the local New York City area!
Please check out our website for more information on how to become involved: sinclaboratory.com/apply
Please check out our website for more information on how to become involved: sinclaboratory.com/apply
Reposted by Brian Sweis
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
October 16, 2025 at 3:00 PM
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
Reposted by Brian Sweis
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function
Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...
nature.com
October 15, 2025 at 8:18 PM
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Reposted by Brian Sweis
Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
September 29, 2025 at 4:31 PM
Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
Reposted by Brian Sweis
We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠
September 22, 2025 at 11:54 AM
We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠
Reposted by Brian Sweis
So excited for this! Can't wait to see everyone there!
We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠
September 24, 2025 at 8:06 PM
So excited for this! Can't wait to see everyone there!
Reposted by Brian Sweis
The amygdala helps mobilize #Stress hormones cortisol & adrenaline w/in about 15 minutes. A recent study by Icahn Mount Sinai's Dr. Sarah Stanley suggests a 2nd role for the #Amygdala in response to #Fear & #Anxiety. Dr. Stanley discusses her research @pnas.org 👉 www.pnas.org/post/journal...
September 22, 2025 at 5:46 PM
Reposted by Brian Sweis
The Sosa Lab website is now live!
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
Sosa Lab
www.sosaneurolab.com
September 22, 2025 at 9:23 PM
The Sosa Lab website is now live!
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
#FluorescentFriday The lab’s 1st slice physiology recordings! Timelapse recording of striatal neurons ex vivo using a Thy1-GCaMP mouse 🐭 🧠 + glutamate in the bath. Thanks @neuromanonyc.bsky.social! Shout out to @keyenceusa.bsky.social who has been great to work with customizing the BZ-X800🔬
September 13, 2025 at 1:59 AM
#FluorescentFriday The lab’s 1st slice physiology recordings! Timelapse recording of striatal neurons ex vivo using a Thy1-GCaMP mouse 🐭 🧠 + glutamate in the bath. Thanks @neuromanonyc.bsky.social! Shout out to @keyenceusa.bsky.social who has been great to work with customizing the BZ-X800🔬
Reposted by Brian Sweis
Couldn’t be more excited to see this work out!! Not just manipulating PV+ cell theta phase, but also shifting seizure susceptibility! how much cooler can it get?!!!
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
September 11, 2025 at 5:12 PM
Couldn’t be more excited to see this work out!! Not just manipulating PV+ cell theta phase, but also shifting seizure susceptibility! how much cooler can it get?!!!
Reposted by Brian Sweis
Check out new work from our lab! We developed a new way to directly control the precise timing of interneurons during behavior and found that theta phase locking is a causal mediator of seizure susceptibility in both healthy and epileptic mice.
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
September 11, 2025 at 7:13 PM
Check out new work from our lab! We developed a new way to directly control the precise timing of interneurons during behavior and found that theta phase locking is a causal mediator of seizure susceptibility in both healthy and epileptic mice.
Reposted by Brian Sweis
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
September 11, 2025 at 5:07 PM
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
Reposted by Brian Sweis
Neuro Current Ep. 38 features #JNeurosci authors discussing their paper on disrupted choice behaviors in a rat model of FASD. Listen to learn more about their methods.
🎧Listen: vist.ly/45w9g
📺 Watch on demand: vist.ly/45w99
🎧Listen: vist.ly/45w9g
📺 Watch on demand: vist.ly/45w99
September 6, 2025 at 11:30 PM
Neuro Current Ep. 38 features #JNeurosci authors discussing their paper on disrupted choice behaviors in a rat model of FASD. Listen to learn more about their methods.
🎧Listen: vist.ly/45w9g
📺 Watch on demand: vist.ly/45w99
🎧Listen: vist.ly/45w9g
📺 Watch on demand: vist.ly/45w99
Congrats Herbert and team!
Super excited to share the first cooperative foraging paradigm in freely interacting mouse pairs! Stable leader and follower roles emerge spontaneously and predict learning. Well-trained mice show stereotyped, role-specific “behavioral motifs” absent in naive animals (1/5)
doi.org/10.1101/2025...
doi.org/10.1101/2025...
September 4, 2025 at 10:50 PM
Congrats Herbert and team!
Reposted by Brian Sweis
Research Network 2023 Pilot & Feasibility awardee @brianmsweis.bsky.social published two papers in Science Advances in July of this year that feature his research on the neuroeconomics of decision making. Join us in congratulating Dr. Sweis!
shorturl.at/d65WV
shorturl.at/DoU4p
shorturl.at/d65WV
shorturl.at/DoU4p
Change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex in a sex-dependent manner
Long non-coding RNA LINC00473 in mPFC alters change-of-mind re-evaluative decision-making behavior related to negative rumination.
shorturl.at
August 7, 2025 at 9:02 PM
Research Network 2023 Pilot & Feasibility awardee @brianmsweis.bsky.social published two papers in Science Advances in July of this year that feature his research on the neuroeconomics of decision making. Join us in congratulating Dr. Sweis!
shorturl.at/d65WV
shorturl.at/DoU4p
shorturl.at/d65WV
shorturl.at/DoU4p
Reposted by Brian Sweis
Welcome to one of our newest @acnporg.bsky.social Associate Members, Dr. Brian Sweis 🎉
#WelcomeToACNP👋
#WelcomeToACNP👋
Congrats to Brian Sweis, M.D., Ph.D. a new Associate Member of ACNP! Welcome!! 👋
July 29, 2025 at 3:11 PM
Welcome to one of our newest @acnporg.bsky.social Associate Members, Dr. Brian Sweis 🎉
#WelcomeToACNP👋
#WelcomeToACNP👋
Reposted by Brian Sweis
Congrats to Brian Sweis, M.D., Ph.D. a new Associate Member of ACNP! Welcome!! 👋
July 29, 2025 at 3:00 PM
Congrats to Brian Sweis, M.D., Ph.D. a new Associate Member of ACNP! Welcome!! 👋
Reposted by Brian Sweis
Abstract submission open for The Mechanistic Basis of Foraging 2025 (U. Birmingham, 3-5 November)
uobevents.eventsair.com/the-mechanis...
Deadline: August 17
A meeting for all fascinated by the brain's role in foraging
Pls share!
uobevents.eventsair.com/the-mechanis...
Deadline: August 17
A meeting for all fascinated by the brain's role in foraging
Pls share!
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
July 25, 2025 at 8:02 AM
Abstract submission open for The Mechanistic Basis of Foraging 2025 (U. Birmingham, 3-5 November)
uobevents.eventsair.com/the-mechanis...
Deadline: August 17
A meeting for all fascinated by the brain's role in foraging
Pls share!
uobevents.eventsair.com/the-mechanis...
Deadline: August 17
A meeting for all fascinated by the brain's role in foraging
Pls share!
This speaks to the importance of cross-species research that is constantly forward- & back-translated between the clinic & lab. The importance of animal models leading to unanticipated discoveries - even in the realm of human psychology - is invaluable, especially in psychiatry🧠 tinyurl.com/yur3j2n8
July 15, 2025 at 1:54 AM
This speaks to the importance of cross-species research that is constantly forward- & back-translated between the clinic & lab. The importance of animal models leading to unanticipated discoveries - even in the realm of human psychology - is invaluable, especially in psychiatry🧠 tinyurl.com/yur3j2n8