Jonah Padawer-Curry, PhD
@jonahpadawercurry.bsky.social
Postdoctoral Fellow in the Satterthwaite lab | Studying brain dynamics and neuroimaging | Music after hours
Pinned
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function
Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...
nature.com
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Reposted by Jonah Padawer-Curry, PhD
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of mouse and human brain function
@adamqbauer.bsky.social
@jordacular.bsky.social
@realjoshsiegel.bsky.social
@oliverk28.bsky.social
www.nature.com/articles/s41...
@adamqbauer.bsky.social
@jordacular.bsky.social
@realjoshsiegel.bsky.social
@oliverk28.bsky.social
www.nature.com/articles/s41...
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function - Nature Neuroscience
Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI studies of psychedelics.
www.nature.com
October 22, 2025 at 7:10 PM
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of mouse and human brain function
@adamqbauer.bsky.social
@jordacular.bsky.social
@realjoshsiegel.bsky.social
@oliverk28.bsky.social
www.nature.com/articles/s41...
@adamqbauer.bsky.social
@jordacular.bsky.social
@realjoshsiegel.bsky.social
@oliverk28.bsky.social
www.nature.com/articles/s41...
Reposted by Jonah Padawer-Curry, PhD
A study in Nature Neuroscience finds psychedelics disrupt the relationship between neuronal activity and blood flow in humans and mice. This suggests fMRI results under psychedelics may reflect vascular effects as much as neural ones and should be interpreted with caution. go.nature.com/47hqVPH 🧪
October 18, 2025 at 1:00 PM
A study in Nature Neuroscience finds psychedelics disrupt the relationship between neuronal activity and blood flow in humans and mice. This suggests fMRI results under psychedelics may reflect vascular effects as much as neural ones and should be interpreted with caution. go.nature.com/47hqVPH 🧪
And the story continues to grow!!!
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
October 16, 2025 at 10:12 PM
And the story continues to grow!!!
Reposted by Jonah Padawer-Curry, PhD
New preprint from collaboration with @sn-lab.bsky.social - 2p imaging of psilocybin's effects on neurovascular coupling 🧠🔬
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
August 1, 2025 at 5:30 PM
New preprint from collaboration with @sn-lab.bsky.social - 2p imaging of psilocybin's effects on neurovascular coupling 🧠🔬
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function
Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...
nature.com
October 15, 2025 at 8:18 PM
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging