Bosse lab at CSSB Hamburg
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bosse-lab.bsky.social
Bosse lab at CSSB Hamburg
@bosse-lab.bsky.social
Illuminating viruses @CSSBHamburg. Check out herpesfolds.org for a comprehensive proteome-wide structural prediction database. A little zoo at home. Equal responsibility dad of three. Views own
f you’re interested in our latest developments have a look at: Comparative Systems Virology Symposium: Jens Bosse youtu.be/PlAcAR1-IJA?si… via @YouTube

Thanks to the @czbiohub for organizing and my amazing team for the great data!
Comparative Systems Virology Symposium: Jens Bosse
YouTube video by Chan Zuckerberg Biohub Network
https://youtu.be/PlAcAR1-IJA?si…
August 25, 2025 at 11:28 PM
A big thanks to Carolina Arias, Amy Kistler and Noam Stern-Ginossar for organizing an amazing meeting on comparative systems virology yesterday @czbiohub.bsky.social in San Francisco!

www.czbiohub.org/events/front...
Frontiers in Comparative Systems Virology Symposium 2025
Be part of this exciting gathering to shape the future of comparative systems virology!
www.czbiohub.org
August 19, 2025 at 1:25 PM
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Are you interested in supporting a young international team of scientists as a part-time job? We have an open 25% team assistant position in our lab in Hamburg at the Centre for Structural Systems Biology (CSSB)! Please apply via: mhh.hr4you.org/job/view/327...
Team Assistant (f/d/m)
mhh.hr4you.org
June 26, 2025 at 7:49 AM
Reposted by Bosse lab at CSSB Hamburg
Congratulations to Thomas Mettenleiter for winning this year's Loeffler Frosch Medal awarded for his special service to virology as the long-term President of the Friedrich-Löffler Institut
March 5, 2025 at 5:09 PM
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The third session of our symposium is Bacteria. The session begins on May 8 with a talk by Hinrich Schulenburg from @uni-kiel.de

Register today: cssb-hamburg.de/symposium2025

@carobarisch.bsky.social @bosse-lab.bsky.social @topf-lab.bsky.social @landaulabcssb.bsky.social @jankosinski.bsky.social
March 4, 2025 at 2:29 PM
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Check out this video summary of the first day of our upcoming symposium "Mechanisms of Infection - from structure to translation."

Register by April 8: t1p.de/gztmj

@bosse-lab.bsky.social, @carobarisch.bsky.social, @jankosinski.bsky.social, @meytallandau.bsky.social @topf-lab.bsky.social
February 25, 2025 at 10:30 AM
Reposted by Bosse lab at CSSB Hamburg
Alan Cowman from WEHI @wehi-research.bsky.social will give the second talk in our Parasites session on May 7.

Register to attend by April 8: t1p.de/gztmj

@carobarisch.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @robinsonmeyer.bsky.social
February 14, 2025 at 12:45 PM
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The fourth and final speaker in the Parasites session of our symposium is Ron Dzikowski from The Hebrew University of Jerusalem.

Register for the symposium by April 8: t1p.de/gztmj

@leibnizliv.bsky.social @fzborstel.bsky.social @uni-hamburg.de @embl.org @helmholtzhzi.bsky.social
February 19, 2025 at 1:25 PM
Reposted by Bosse lab at CSSB Hamburg
CSSB alumnus Michael Filarsky from @unituebingen.bsky.social will give a talk during our "Parasites" session on May 7.

Take a look at the symposium programme here:
t1p.de/h48ek

@leibnizliv.bsky.social @fzborstel.bsky.social @helmholtzhzi.bsky.social @uni-hamburg.de
February 18, 2025 at 2:29 PM
Reposted by Bosse lab at CSSB Hamburg
The second session of our symposium is "Parasites".

Emily Derbyshire's talk entitled "Interdisciplinary approaches to reveal parasite vulnerabilities" will start the session.

Register by April 8: t1p.de/gztmj

@meytallandau.bsky.social @carobarisch.bsky.social @bosse-lab.bsky.social
February 11, 2025 at 2:23 PM
Reposted by Bosse lab at CSSB Hamburg
On May 7, Ilaria Ferlenghi from GSK will give a talk entitled "Fast-Track to Immunity: The Fusion of Structural Biology, AI, and ML in Vaccine Innovation"

Register today: t1p.de/gztmj

@carobarisch.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @meytallandau.bsky.social
February 10, 2025 at 12:38 PM
Reposted by Bosse lab at CSSB Hamburg
🚨 Save the date! 🚨
We're thrilled to announce our International Symposium on Cell & Structural Biology of Host-Pathogen Interaction
📅 Sept 10-12, 2025
📍
@cssbhamburg.bsky.social Hamburg

Registration starts soon
For more info:
humansandmicrobes2025.de
January 29, 2025 at 1:21 PM
Reposted by Bosse lab at CSSB Hamburg
Our symposium "Mechanisms of Infection: from structure to translation" will take place from May 7-8.

Over the next weeks, we will be introducing our 15 confirmed speakers.

Sriram Subramaniam from the University of British Columbia will be giving the key note.

www.cssb-hamburg.de/symposium2025
February 3, 2025 at 1:16 PM
Reposted by Bosse lab at CSSB Hamburg
The first session of our symposium "Mechanisms of Infection: from structure to translation" is Viruses.

Ben tenOever from New York University will give the first talk in this session.

t1p.de/xu79k

@carobarisch.bsky.social @bosse-lab.bsky.social @topf-lab.bsky.social @jankosinski.bsky.social
February 4, 2025 at 9:47 AM
About 1,5 years ago I predicted in a little writeup for the ExC RESIST that ever more capable LLMs will soon make scientific review articles obsolete. From the initial results I have from #OpenAIs #DeepResearch, this is happening very soon…
February 4, 2025 at 7:35 AM
Reposted by Bosse lab at CSSB Hamburg
We are very excited that our in-situ structural analysis of the Ebola virus nucleocapsid assembly cascade is now published in @cellpress.bsky.social!
January 7, 2025 at 10:13 AM
Join us in Hamburg, 7th-8th of May, at the CSSB! cssb-hamburg.de/symposium2025
December 17, 2024 at 8:37 AM
Reposted by Bosse lab at CSSB Hamburg
Conclusion of RNA assessors in #CASP16 - we are still in the “template” phase. Prediction of nucleic acids structure is still challenging for targets without templates, often relying on intuition. No big leap in accuracy since CASP15. AI based methods have not (yet?) made a major difference.
December 3, 2024 at 1:30 PM
Reposted by Bosse lab at CSSB Hamburg
Stone conclusion by hearsay from day 1 at #CASP16 all top methods used AF3 somehow. Improvements are made by increased sampling (FFT etc), ranking of models still a challenge. Some improvement on antibodies.
December 3, 2024 at 4:21 PM
Reposted by Bosse lab at CSSB Hamburg
Conclusions from RNA section at #CASP16, without a template all fail. All small targets had a template.
December 3, 2024 at 4:10 PM
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Conclusion for ligand session in #casp16, without a template methods fail
December 3, 2024 at 7:32 PM
Reposted by Bosse lab at CSSB Hamburg
#CASP16: are we making progress in predicting protein-protein complexes?Not much in general, but ….

One method (Kozakov Vajda) shows great improvement in predicting structure of antibody-antigen complexes. 🧪 🧬
December 2, 2024 at 3:06 PM
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#CASP16 assessors’ summary of the protein complex category 🧪 🧬
December 2, 2024 at 3:24 PM
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Assessors’ conclusions of the 3D category (individual protein chains) of #CASP16 🧪
December 2, 2024 at 2:22 PM