A.Bosson
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astroantho.bsky.social
A.Bosson
@astroantho.bsky.social
Astrocyte nerd
CRCHUM - Montreal
Murphy-Royal lab
https://www.murphyroyallab.org/
Pinned
A touch of blue velvet LUT with this #FluorescenceFriday

GCaMP8 astrocytic activities at the 2p
The views we are lucky to witness from the @crchum.bsky.social
November 4, 2025 at 9:47 PM
Reposted by A.Bosson
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
October 15, 2025 at 4:11 PM
Reposted by A.Bosson
Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉
August 19, 2025 at 4:26 PM
Go Lewis 👏👏👏
July 11, 2025 at 5:32 PM
Reposted by A.Bosson
Sleep loss is a metabolic disorder

"This review describes how sleep deprivation increases resting energy expenditure, leading to the development of a negative energy balance in highly active cells like neurons."

www.science.org/doi/10.1126/...
Sleep loss is a metabolic disorder
Sleep deprivation shifts metabolic resources and deprioritizes processes that support cognition.
www.science.org
May 28, 2025 at 12:01 AM
Happy to see that the 2nd part (2018 to 2021) of my postdoc work is now out as a preprint.
Distinct subtypes of astrocytes selectively regulate specific inhibitory synapses https://www.biorxiv.org/content/10.1101/2025.05.16.654545v1
May 22, 2025 at 11:18 AM
Reposted by A.Bosson
@lewisholt.bsky.social sharing some cool data about astrocytes driving stress-induced behaviour! #astroglia
May 20, 2025 at 3:23 PM
Reposted by A.Bosson
Very happy to share several common protocols used in our lab for the second edition of the book "Astrocytes: Methods and Protocols"
@lewisholt.bsky.social @astroantho.bsky.social

Thanks @dibenedetto-lab.bsky.social for being a very patient editor!

link.springer.com/book/10.1007...
Astrocytes
This book gathers methods essential for investigating the multifaceted roles of astrocytes in both physiology and pathological conditions.
link.springer.com
March 21, 2025 at 5:30 PM
Reposted by A.Bosson
Montréal glia people / neuroscience community - I'm hosting Jun Nagai (RIKEN) on April 2nd at the @crchum.bsky.social
If you're interested see details below, or reach out to me! Open to all.
March 19, 2025 at 4:10 PM
Reposted by A.Bosson
Not sure if our 'striking image' we submitted will get used but here it is. Super striking, if you ask me!

Credit - @mathiasgua.bsky.social
February 5, 2025 at 4:28 PM
Reposted by A.Bosson
Astrocyte physiologists and computationalists!

Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge ⭐

doi.org/10.7554/eLif...
A spatial threshold for astrocyte calcium surge
In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integrat...
doi.org
January 20, 2025 at 1:53 PM
A touch of blue velvet LUT with this #FluorescenceFriday

GCaMP8 astrocytic activities at the 2p
January 17, 2025 at 3:09 PM
Reposted by A.Bosson
How convenient - this tree already comes with ornaments! 🎄🧪

Get into the holiday spirit with this beautiful cell tree by @oozguc.bsky.social from @ibecbarcelona.eu. This beautiful fusion of science and art was made using our Lamin B1 stem cell line!

What would you want to see under your cell tree?
December 17, 2024 at 11:55 PM
2 eGFP #astrocytes contacting a blood vessel with their arborization almost looking like a christmas tree for this #fluorescencefriday #astrocyte
December 20, 2024 at 5:41 PM
Reposted by A.Bosson
Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review.
Colossal work by the team and driven home by @mathiasgua.bsky.social
Quick 🧵 of what's new -
www.biorxiv.org/content/10.1...
Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
Early-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have ...
www.biorxiv.org
December 9, 2024 at 11:19 PM
Reposted by A.Bosson
we haven't talked about this in the SKY>

exciting preprint from Kevin Guttenplan in Marc Freeman's lab at @volluminstitute.bsky.social

Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity

www.biorxiv.org/content/10.1...
December 6, 2024 at 9:06 PM
Reposted by A.Bosson
10/ Why should you bring #preprints into your journal club?

Here’s what #ECRs stand to gain by looking beyond published papers.
https://buff.ly/3VbvNjT
Point of View: Journal clubs in the time of preprints
Early-career researchers can learn about peer review by discussing preprints at journal clubs and sending feedback to the authors.
buff.ly
November 26, 2024 at 3:42 PM
Reposted by A.Bosson
New paper from our neighbours Stephanie Fulton’s lab investigating microglia, inflammation and synaptic transmission in the NAc.
www.biorxiv.org/content/10.1...
Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult
Neuroimmune responses to systemic inflammation can generate anxiodepressive behaviors and psychomotor slowing. The nucleus accumbens (NAc) is a neural hub encoding mood and motivation that contributes...
www.biorxiv.org
December 3, 2024 at 1:57 PM
Reposted by A.Bosson
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?

go.bsky.app/MHtJzeC
November 17, 2024 at 8:35 PM
Reposted by A.Bosson
Not sure I have any good pictures in the back pocket to beat the calcium imaging from @mathiasgua.bsky.social

Instead for my first post on Bluesky I want to share the CANglia webinar: trainee series!
November 15, 2024 at 6:20 PM
Reposted by A.Bosson
Still thinking about which neuroscience conferences to attend next year?

Explore our events page, featuring a curated list of top neuroscience meetings with topic-based filters. Plus, check out upcoming webinars compiled by @worldwideneuro.bsky.social.

thetransmitter.org/events
November 20, 2024 at 4:23 PM
Reposted by A.Bosson
Interesting to see how this is all shaping up! I’m still really proud that the first data paper from my lab went into eLife with the new model, which I think is a great system.
(We’ll be updating the manuscript based on these reviews in the very near future)
Following the news that eLife will not receive an Impact Factor in 2025, we’ve shared an update on how our model is doing since we were first placed “on hold” by Web of Science, and what we’re up to now. Find out more.
https://buff.ly/3ATRAFT
The eLife Model: An update on progress following changes in Web of Science indexing status
Following the decision that eLife will not receive an Impact Factor in 2025, we share an update on how our model is doing since we were first placed “on hold” by Web of Science, and what we’re up to…
buff.ly
November 20, 2024 at 5:58 PM