Areeba Patel
@areebap.bsky.social
AI, (epi-)genomics, pathology |
Head of Tech @ Heidelberg Epignostix |
PhD @dkfz.bsky.social with Felix Sahm and @moritzgerstung.bsky.social | @imperialcollegeldn.bsky.social alum
Head of Tech @ Heidelberg Epignostix |
PhD @dkfz.bsky.social with Felix Sahm and @moritzgerstung.bsky.social | @imperialcollegeldn.bsky.social alum
Pinned
Areeba Patel
@areebap.bsky.social
· Mar 25
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors - Nature Medicine
Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...
www.nature.com
Kicking off my BlueSky account with a 🚨 new paper alert!!
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Reposted by Areeba Patel
Congratulations to Felix Sahm, recipient of the #EANO Research Award 2025!
This award recognises his outstanding contributions to basic, translational, and clinical research in #NeuroOncology and #Neuropathology.
#EANO2025 #ResearchExcellence
@dkfz.bsky.social
This award recognises his outstanding contributions to basic, translational, and clinical research in #NeuroOncology and #Neuropathology.
#EANO2025 #ResearchExcellence
@dkfz.bsky.social
October 17, 2025 at 12:08 PM
Congratulations to Felix Sahm, recipient of the #EANO Research Award 2025!
This award recognises his outstanding contributions to basic, translational, and clinical research in #NeuroOncology and #Neuropathology.
#EANO2025 #ResearchExcellence
@dkfz.bsky.social
This award recognises his outstanding contributions to basic, translational, and clinical research in #NeuroOncology and #Neuropathology.
#EANO2025 #ResearchExcellence
@dkfz.bsky.social
Reposted by Areeba Patel
A spatial transcriptomics analysis led by my student Zaira reveals the distinct nature (gene expression, tumour cell states and local microenvironments) of radionecrosis and recurrence in glioblastoma. 👏
🚨 new glioblastoma preprint alert!
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
October 7, 2025 at 5:12 AM
A spatial transcriptomics analysis led by my student Zaira reveals the distinct nature (gene expression, tumour cell states and local microenvironments) of radionecrosis and recurrence in glioblastoma. 👏
Reposted by Areeba Patel
🚨 new glioblastoma preprint alert!
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
October 6, 2025 at 12:41 PM
🚨 new glioblastoma preprint alert!
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.
🧵 1/
Reposted by Areeba Patel
What if you could get a glimpse of the future of your health, today?
Our scientists have developed a new generative AI model, trained using large-scale health records, that can estimate how human health may change over time.
Watch to find out more.
🖥️🧬
Our scientists have developed a new generative AI model, trained using large-scale health records, that can estimate how human health may change over time.
Watch to find out more.
🖥️🧬
September 17, 2025 at 3:23 PM
What if you could get a glimpse of the future of your health, today?
Our scientists have developed a new generative AI model, trained using large-scale health records, that can estimate how human health may change over time.
Watch to find out more.
🖥️🧬
Our scientists have developed a new generative AI model, trained using large-scale health records, that can estimate how human health may change over time.
Watch to find out more.
🖥️🧬
Reposted by Areeba Patel
A paper in Nature presents a new artificial intelligence model that can predict how a person’s health might change over their lifetime. This tool could help doctors and health planners to better understand and prepare for personalized medical needs. go.nature.com/4n6giWi #medsky 🧪
September 18, 2025 at 4:36 PM
A paper in Nature presents a new artificial intelligence model that can predict how a person’s health might change over their lifetime. This tool could help doctors and health planners to better understand and prepare for personalized medical needs. go.nature.com/4n6giWi #medsky 🧪
Reposted by Areeba Patel
Advancing sarcoma diagnostics with expanded DNA methylation-based classification https://www.medrxiv.org/content/10.1101/2025.06.30.25330543v1
July 1, 2025 at 2:28 AM
Advancing sarcoma diagnostics with expanded DNA methylation-based classification https://www.medrxiv.org/content/10.1101/2025.06.30.25330543v1
Reposted by Areeba Patel
🧠 June 8 is #WorldBrainTumorDay — raising awareness & understanding of brain tumors.
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
June 8, 2025 at 9:44 AM
🧠 June 8 is #WorldBrainTumorDay — raising awareness & understanding of brain tumors.
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
Reposted by Areeba Patel
Yesterday we had the pleasure of informing our Baden-Württemberg government about the future of biomedical #innovation in Heidelberg/Mannheim.
Thanks to everyone who helped to make this a successful event @michaelboutros.bsky.social @biorncluster.bsky.social
The article is published in German only.
Thanks to everyone who helped to make this a successful event @michaelboutros.bsky.social @biorncluster.bsky.social
The article is published in German only.
Alliance und BioRN im Stuttgarter Landtag
Inspirierender Austausch mit Parlamentarier:innen zum Innovationscampus Health + Life Science Alliance Heidelberg I Mannheim Unter dem Motto "Zukunft Innovationsstandort Baden-Württemberg: Life Scienc...
www.linkedin.com
June 5, 2025 at 12:36 PM
Yesterday we had the pleasure of informing our Baden-Württemberg government about the future of biomedical #innovation in Heidelberg/Mannheim.
Thanks to everyone who helped to make this a successful event @michaelboutros.bsky.social @biorncluster.bsky.social
The article is published in German only.
Thanks to everyone who helped to make this a successful event @michaelboutros.bsky.social @biorncluster.bsky.social
The article is published in German only.
Reposted by Areeba Patel
🧠 Thank you for joining the #EANOYoungsters Journal Club!
Over 200 attendees from around the world joined us to discuss CNS tumor profiling (Patel et al., Nat Med, 2025).
▶️ Missed it? Watch the recording soon on our YouTube: www.youtube.com/@eano_associ...
#NeuroOncology #CNScancer
Over 200 attendees from around the world joined us to discuss CNS tumor profiling (Patel et al., Nat Med, 2025).
▶️ Missed it? Watch the recording soon on our YouTube: www.youtube.com/@eano_associ...
#NeuroOncology #CNScancer
June 5, 2025 at 3:42 PM
🧠 Thank you for joining the #EANOYoungsters Journal Club!
Over 200 attendees from around the world joined us to discuss CNS tumor profiling (Patel et al., Nat Med, 2025).
▶️ Missed it? Watch the recording soon on our YouTube: www.youtube.com/@eano_associ...
#NeuroOncology #CNScancer
Over 200 attendees from around the world joined us to discuss CNS tumor profiling (Patel et al., Nat Med, 2025).
▶️ Missed it? Watch the recording soon on our YouTube: www.youtube.com/@eano_associ...
#NeuroOncology #CNScancer
Reposted by Areeba Patel
🧠 Join the next #EANOYoungsters Journal Club on June 5, 16:30–17:30 CEST!
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
📍Free & open to all EANO members
🔗 www.eano.eu
#NeuroOncology #BrainTumors #JournalClub
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
📍Free & open to all EANO members
🔗 www.eano.eu
#NeuroOncology #BrainTumors #JournalClub
May 15, 2025 at 9:45 AM
🧠 Join the next #EANOYoungsters Journal Club on June 5, 16:30–17:30 CEST!
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
📍Free & open to all EANO members
🔗 www.eano.eu
#NeuroOncology #BrainTumors #JournalClub
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
📍Free & open to all EANO members
🔗 www.eano.eu
#NeuroOncology #BrainTumors #JournalClub
Reposted by Areeba Patel
The organizing committee of the UNITE conference would like to thank all speakers for their excellent presentations and all participants for the valuable discussions. @wickwolfgang.bsky.social @michael-platten.bsky.social
May 15, 2025 at 2:08 PM
The organizing committee of the UNITE conference would like to thank all speakers for their excellent presentations and all participants for the valuable discussions. @wickwolfgang.bsky.social @michael-platten.bsky.social
Reposted by Areeba Patel
🧠 A recent publication in Nature Medicine covers the prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors.
🔗 Learn more: doi.org/10.1038/s415...
#MalignantBrainTumor #NeuroOncology #BrainTumors #EANOessentials
🔗 Learn more: doi.org/10.1038/s415...
#MalignantBrainTumor #NeuroOncology #BrainTumors #EANOessentials
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors - Nature Medicine
Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...
doi.org
April 4, 2025 at 12:00 PM
🧠 A recent publication in Nature Medicine covers the prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors.
🔗 Learn more: doi.org/10.1038/s415...
#MalignantBrainTumor #NeuroOncology #BrainTumors #EANOessentials
🔗 Learn more: doi.org/10.1038/s415...
#MalignantBrainTumor #NeuroOncology #BrainTumors #EANOessentials
Kicking off my BlueSky account with a 🚨 new paper alert!!
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors - Nature Medicine
Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...
www.nature.com
March 25, 2025 at 2:13 PM
Kicking off my BlueSky account with a 🚨 new paper alert!!
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Thrilled to share that my final PhD paper is now out in Nature Medicine @natmedicine.bsky.social 🎉
🔗 www.nature.com/articles/s41...
#MethylationClassification #MolecularDiagnostics #CNSTumours #NanoporeSequencing
Reposted by Areeba Patel
New Preprint klaxon - and calling all Danes+Brits who are interested in genetics+history - a new preprint led by Xiaolei Zhang in my group with Soren Brunak's group about genetic exchange from 1100 to the present day between UK (Britain)+Denmark. Read on for details www.biorxiv.org/content/10.1...
Population-scale analysis of inheritance patterns across 858,635 individuals reveals recent historical migration patterns across the North Sea from the Middle Ages to the Industrial Revolution
The North Sea's historical migrations have impacted the genetic structure of its neighbouring populations. We analysed haplotype sharing among 858,635 modern individuals from Denmark and Britain to in...
www.biorxiv.org
March 20, 2025 at 7:34 AM
New Preprint klaxon - and calling all Danes+Brits who are interested in genetics+history - a new preprint led by Xiaolei Zhang in my group with Soren Brunak's group about genetic exchange from 1100 to the present day between UK (Britain)+Denmark. Read on for details www.biorxiv.org/content/10.1...
Reposted by Areeba Patel
Spatial transcriptomics holds great promise to understand biological tissue function, but the assignment of transcripts to cells has been a substantial bottleneck.
For this reason, Elyas Heidari, a student in my lab and in @steglelab.bsky.social built segger.
www.biorxiv.org/content/10.1...
For this reason, Elyas Heidari, a student in my lab and in @steglelab.bsky.social built segger.
www.biorxiv.org/content/10.1...
March 17, 2025 at 4:19 PM
Spatial transcriptomics holds great promise to understand biological tissue function, but the assignment of transcripts to cells has been a substantial bottleneck.
For this reason, Elyas Heidari, a student in my lab and in @steglelab.bsky.social built segger.
www.biorxiv.org/content/10.1...
For this reason, Elyas Heidari, a student in my lab and in @steglelab.bsky.social built segger.
www.biorxiv.org/content/10.1...
Reposted by Areeba Patel
1/ New preprint! 🍳
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
March 18, 2025 at 2:48 PM
1/ New preprint! 🍳
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
Reposted by Areeba Patel
Great to be visiting @nanoporetech.com as part of a cns Nanopore symposium meeting with pathologists and clinical scientists to discuss the application of nanopore sequencing in the clinic.
March 5, 2025 at 10:51 AM
Great to be visiting @nanoporetech.com as part of a cns Nanopore symposium meeting with pathologists and clinical scientists to discuss the application of nanopore sequencing in the clinic.
Reposted by Areeba Patel
A new open access article: cIMPACT-NOW update 9 – recommendations on genome-wide DNA methylation profiling for CNS tumor diagnostics – is now available in Neuro Oncology Advances 🔗 academic.oup.com/noa/article/... 🔓 #EANOessentials #NeuroOncology #MalignantBrainTumor
cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnostics
Abstract. Genome-wide DNA methylation signatures correlate with and distinguish central nervous system (CNS) tumor types. Since the publication of the init
academic.oup.com
February 24, 2025 at 6:34 PM
A new open access article: cIMPACT-NOW update 9 – recommendations on genome-wide DNA methylation profiling for CNS tumor diagnostics – is now available in Neuro Oncology Advances 🔗 academic.oup.com/noa/article/... 🔓 #EANOessentials #NeuroOncology #MalignantBrainTumor
Reposted by Areeba Patel
New paper alert! We’ve identified a distinct subset of IDH-mutant astrocytomas harboring a primitive neuronal component.
A big shoutout to Felix Hinz, Niek Maas and to the entire team for their incredible effort!
link.springer.com/article/10.1...
A big shoutout to Felix Hinz, Niek Maas and to the entire team for their incredible effort!
link.springer.com/article/10.1...
IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread - Acta Neuropathologica
IDH-mutant astrocytomas are diffuse gliomas that are defined by characteristic mutations in IDH1 or IDH2 and do not have complete 1p/19q co-deletion. The established grading criteria include histologi...
link.springer.com
February 5, 2025 at 2:50 PM
New paper alert! We’ve identified a distinct subset of IDH-mutant astrocytomas harboring a primitive neuronal component.
A big shoutout to Felix Hinz, Niek Maas and to the entire team for their incredible effort!
link.springer.com/article/10.1...
A big shoutout to Felix Hinz, Niek Maas and to the entire team for their incredible effort!
link.springer.com/article/10.1...
Reposted by Areeba Patel
1/2 Super excited to see this finally out @naturecomms.bsky.social ! We developed an off-the-shelf T cell receptor T cell therapy for patients with glioblastoma from a peptide vaccinated patient. Looking very much forward to its translation within DKTK supported by HI-TRON!
Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen - Nature Communications
Vaccination in glioblastomas does lead to the emergence of tumour-antigen-specific T cells but T cell dysfunction, poor tumour infiltration and persistence hinder efficient tumour killing. Here author...
www.nature.com
February 2, 2025 at 9:08 PM
1/2 Super excited to see this finally out @naturecomms.bsky.social ! We developed an off-the-shelf T cell receptor T cell therapy for patients with glioblastoma from a peptide vaccinated patient. Looking very much forward to its translation within DKTK supported by HI-TRON!
Reposted by Areeba Patel
Computational with a PhD in some quantiative science, and want to make the world a better place with AI in healthcare? Want to work with some of the most innovative AI groups in the life sciences? Want to work for Europe, across Cambridge and Heidelberg, living in the UK? Two more days to apply:
NEW: Postdoctoral Fellow with @ewanbirney
The project is based in the Birney Research group at @emblebi and working closely with Open Targets and @MoritzGerstung's group at DKFZ
The project is based in the Birney Research group at @emblebi and working closely with Open Targets and @MoritzGerstung's group at DKFZ
December 6, 2024 at 11:19 AM
Computational with a PhD in some quantiative science, and want to make the world a better place with AI in healthcare? Want to work with some of the most innovative AI groups in the life sciences? Want to work for Europe, across Cambridge and Heidelberg, living in the UK? Two more days to apply: