Anna Nemudraia
anemudraia.bsky.social
Anna Nemudraia
@anemudraia.bsky.social
Reposted by Anna Nemudraia
Exciting times ahead!

Today marks the first day of the Loeff Lab at Leiden University Medical Center in the Netherlands 🇳🇱. I’m thrilled to begin this new adventure and continue exploring microbial defense mechanisms and their applications through an integrative structural biology approach.
August 18, 2025 at 2:54 PM
Reposted by Anna Nemudraia
New preprint from the Wiedenheft lab!

We used #cryoEM to show how a type I-F #CRISPR integrase captures, delivers, and integrates foreign DNA.
www.biorxiv.org/content/10.1...
June 18, 2025 at 1:21 AM
Reposted by Anna Nemudraia
First preprint from the Nemudryi Lab! 🍾

In this work, we link antiviral immunity in bacteria and humans by showing that homologs of human Schlafen nucleases protect bacteria from phages.

www.biorxiv.org/content/10.1...
Bacterial Schlafens mediate anti-phage defense
Human Schlafen proteins restrict viral replication by cleaving tRNA, thereby suppressing protein synthesis. Although the ribonuclease domain of Schlafen proteins is conserved across all domains of lif...
www.biorxiv.org
July 25, 2025 at 2:52 PM
Reposted by Anna Nemudraia
@anemudraia.bsky.social and I are grateful to our very first team members, Veronica, Yimo, and Riley, who bravely joined the lab early on and worked hard on this project!

And big thanks to our collaborators, @lloeff.bsky.social and @kirillemedvedev.bsky.social. Excited for what’s next!
July 25, 2025 at 2:52 PM
Reposted by Anna Nemudraia
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏

youtu.be/8YhJM6zxYDw?...
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
youtu.be
May 24, 2025 at 1:13 AM