Anbang James Dai
@anbangdai.bsky.social
Postdoc @PDC Lab @Yale/HHMI
PhD from Hong-Wei Wang lab in School of Life Sciences @Tsinghua University
PhD from Hong-Wei Wang lab in School of Life Sciences @Tsinghua University
Reposted by Anbang James Dai
The Hanna lab is looking for an enthusiastic Research Technologist to join the team! 😊
You’ll help lead projects focused on organelle health & resilience to establish momentum in the lab. 🔬🥽
Job description and details can be found here: psu.wd1.myworkdayjobs.com/PSU_Staff/jo...
You’ll help lead projects focused on organelle health & resilience to establish momentum in the lab. 🔬🥽
Job description and details can be found here: psu.wd1.myworkdayjobs.com/PSU_Staff/jo...
Research Technologist
APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...
psu.wd1.myworkdayjobs.com
October 22, 2025 at 7:09 PM
The Hanna lab is looking for an enthusiastic Research Technologist to join the team! 😊
You’ll help lead projects focused on organelle health & resilience to establish momentum in the lab. 🔬🥽
Job description and details can be found here: psu.wd1.myworkdayjobs.com/PSU_Staff/jo...
You’ll help lead projects focused on organelle health & resilience to establish momentum in the lab. 🔬🥽
Job description and details can be found here: psu.wd1.myworkdayjobs.com/PSU_Staff/jo...
Reposted by Anbang James Dai
See link here: www.cell.com/trends/neuro...
Redefining dopaminergic synapses beyond the classical paradigm
Synapses are traditionally defined by the presence of presynaptic vesicle pools and
postsynaptic densities. Dopaminergic neurons, however, frequently form bouton-like
structures that lack these conven...
www.cell.com
October 15, 2025 at 1:46 PM
See link here: www.cell.com/trends/neuro...
Reposted by Anbang James Dai
Lipid transporter BLTP2 recruitment to ER-plasma membrane contacts controls membrane dynamics
📷 @anbangdai.bsky.social et al @yaleschoolofmed.bsky.social
in @jcb.org
➡️ bpod.org.uk/archive/2025...
📷 @anbangdai.bsky.social et al @yaleschoolofmed.bsky.social
in @jcb.org
➡️ bpod.org.uk/archive/2025...
October 1, 2025 at 2:46 PM
Lipid transporter BLTP2 recruitment to ER-plasma membrane contacts controls membrane dynamics
📷 @anbangdai.bsky.social et al @yaleschoolofmed.bsky.social
in @jcb.org
➡️ bpod.org.uk/archive/2025...
📷 @anbangdai.bsky.social et al @yaleschoolofmed.bsky.social
in @jcb.org
➡️ bpod.org.uk/archive/2025...
Reposted by Anbang James Dai
"Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C" out now in PLOS Biology
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C
VPS13A and VPS13C are bridge-like lipid transport proteins with distinct subcellular localization and function, and their absence is linked with chorea-acanthocytosis and Parkinson's disease, respecti...
journals.plos.org
September 29, 2025 at 1:47 PM
"Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C" out now in PLOS Biology
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Anbang James Dai
New paper alert! I’m very excited to share our paper published in @embojournal.org! @pdc-lab.bsky.social @yaleneuro.bsky.social
Bridge-like lipid transfer protein 3A (BLTP3A) participates in endomembrane repair as an effector of #ATG8 conjugation to single membranes (CASM) - helping repair or minimize #lysosome damage
@mike-hanna.bsky.social et al, @pdc-lab.bsky.social
www.embopress.org/doi/full/10....
@mike-hanna.bsky.social et al, @pdc-lab.bsky.social
www.embopress.org/doi/full/10....
September 12, 2025 at 2:04 PM
New paper alert! I’m very excited to share our paper published in @embojournal.org! @pdc-lab.bsky.social @yaleneuro.bsky.social
Reposted by Anbang James Dai
Just published: the @pdc-lab.bsky.social, led by @anbangdai.bsky.social, sheds light on the localization and function of BLTP2, a bridge-like lipid transfer protein: BLTP2 is found at contacts between the endoplasmic reticulum (ER) & plasma membrane (PM), and plays a key role in PM dynamics.
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics - PubMed
BLTP2/KIAA0100, a bridge-like lipid transfer protein, was reported to localize at contacts of the ER with either the plasma membrane (PM) or recycling tubular endosomes depending on the cell type. Our...
pubmed.ncbi.nlm.nih.gov
September 4, 2025 at 4:36 PM
Just published: the @pdc-lab.bsky.social, led by @anbangdai.bsky.social, sheds light on the localization and function of BLTP2, a bridge-like lipid transfer protein: BLTP2 is found at contacts between the endoplasmic reticulum (ER) & plasma membrane (PM), and plays a key role in PM dynamics.
Reposted by Anbang James Dai
The GTPase-activating protein RABGAP1 is a new interactor of amyloid precursor protein APP, facilitating its trafficking and proteolytic processing
@dgershlick.bsky.social and coworkers @thecimr.bsky.social
www.embopress.org/doi/full/10....
@dgershlick.bsky.social and coworkers @thecimr.bsky.social
www.embopress.org/doi/full/10....
September 1, 2025 at 4:06 PM
The GTPase-activating protein RABGAP1 is a new interactor of amyloid precursor protein APP, facilitating its trafficking and proteolytic processing
@dgershlick.bsky.social and coworkers @thecimr.bsky.social
www.embopress.org/doi/full/10....
@dgershlick.bsky.social and coworkers @thecimr.bsky.social
www.embopress.org/doi/full/10....
Reposted by Anbang James Dai
@anbangdai.bsky.social et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...
September 3, 2025 at 4:15 PM
@anbangdai.bsky.social et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...
Reposted by Anbang James Dai
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice https://www.biorxiv.org/content/10.1101/2025.05.09.653147v1
May 13, 2025 at 11:31 AM
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice https://www.biorxiv.org/content/10.1101/2025.05.09.653147v1
Reposted by Anbang James Dai
"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology
rdcu.be/ehbaL
rdcu.be/ehbaL
The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage
Nature Cell Biology - Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal...
rdcu.be
April 10, 2025 at 2:17 PM
"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology
rdcu.be/ehbaL
rdcu.be/ehbaL