If you need to sample reads (with or without replacement) from FASTQ files you may find the fastQpick utility by Joseph Rich super useful: github.com/pachterlab/f...

Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary Disease
@atscommunity.bsky.social #medsky

🔗 tinyurl.com/kzmb5zxv

We find diverse NKT cells are protective vs brain injury in our study of clinical and murine cardiac arrest

Interested in brain aging? We are super excited to share our new review!!

"Brain aging and rejuvenation at single-cell resolution" 🧪🧠

Massive CONGRATS to Eric Sun, Rahul Nagvekar, and Angie Pogson, three phenomenal graduate students in the lab!!

authors.elsevier.com/sd/article/S...

Bit late with this, but super happy that our neural organoid atlas is out in Nature! Really fun collab with @zhisonghe.bsky.social and @le-and-er.bsky.social between the Treutlein lab, @fabiantheis.bsky.social and @graycamplab.bsky.social.
www.nature.com/articles/s41...

The #NIH is accepting #grant applications for projects to generate "large scale transcriptomic and epigenomic data at the single cell/nucleus level from human brain tissue." Note the deadlines below!
grants.nih.gov/grants/guide...
#transcriptomics #epigenomics #omics

The NeuroICU Board Review 1st Edition
by Saef Izzy (Author), David P. Lerner (Author), Kiwon Lee (Author)

- Publisher ‏ : ‎ McGraw Hill / Medical; 1st edition (November
medicalebooks.org/shop/the-neu...

New method for identifying spatially variable genes in spatial transcriptomics.

We use spectral graph theory to extract 1D curves related to tissue morphology, creating a more relevant coordinate system. Improves sensitivity.

with @PhillipNicol et al.

www.biorxiv.org/content/10.1...

Application of ERS/ATS Spirometry Standards and Race-Neutral Equations in COPDGene

ERS/ATS criteria discriminate survival, imaging characteristics, and exacerbation rates better than GOLD stage, and highlight use of race-neutral spirometry
@atscommunity.bsky.social

🔗 tinyurl.com/mryvmucz

Will have a more detailed post soon, but sharing advanced online pre-proof version of our new study
- Single cell profiling of Hematopoietic Stem Cell Transplant recipients reveals TGF-β1 and IL-2 confer immunoregulatory functions to NK cells: www.cell.com/iscience/ful...

Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence, including a female-specific cytotoxic CD8+ T cell subpopulation @martamele.bsky.social @mariasopenar.bsky.social
papers.ssrn.com/sol3/papers....