Alice Burleigh
@aliceburleigh.bsky.social
Postdoc @ The University of Edinburgh
Investigating topical steroid withdrawal (TSW) in the UK 🤚🏼
Funded by National Eczema Society
Investigating topical steroid withdrawal (TSW) in the UK 🤚🏼
Funded by National Eczema Society
Reposted by Alice Burleigh
Congratulations to Sara Brown who, together with Alice Burleigh, has won a Pump-Priming grant award in the National Eczema Society’s first-ever grant round awards for the first structured study of topical steroid withdrawal in the UK.
edin.ac/3FmhiFp
edin.ac/3FmhiFp
National Eczema Society’s first-ever grant round awards! - National Eczema Society
Exciting announcement: National Eczema Society announce the four winners of their first research grant. Two PhD and two pump-priming projects
edin.ac
May 28, 2025 at 1:42 PM
Congratulations to Sara Brown who, together with Alice Burleigh, has won a Pump-Priming grant award in the National Eczema Society’s first-ever grant round awards for the first structured study of topical steroid withdrawal in the UK.
edin.ac/3FmhiFp
edin.ac/3FmhiFp
Reposted by Alice Burleigh
🚨 EBI has just lunched a new portal to calculate genetic scores from individual-level genetic data.
Check it out 👇. It is very cool!
geneticscores.org
It is linked with the @pgscatalog.bsky.social
This was supported by INTERVENE
Check it out 👇. It is very cool!
geneticscores.org
It is linked with the @pgscatalog.bsky.social
This was supported by INTERVENE
GeneticScores.org
GeneticScores.org provides tools and data to help AI developers and human health researchers make better polygenic scores
geneticscores.org
April 28, 2025 at 11:31 AM
🚨 EBI has just lunched a new portal to calculate genetic scores from individual-level genetic data.
Check it out 👇. It is very cool!
geneticscores.org
It is linked with the @pgscatalog.bsky.social
This was supported by INTERVENE
Check it out 👇. It is very cool!
geneticscores.org
It is linked with the @pgscatalog.bsky.social
This was supported by INTERVENE
Reposted by Alice Burleigh
A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis.
rdcu.be/d9iRG
rdcu.be/d9iRG
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants
Nature Immunology - Gain-of-function variants in the gene encoding NLRP3 lead to constitutive inflammasome activation and excessive IL-1β production. In this resource, authors perform...
rdcu.be
February 11, 2025 at 9:57 AM
A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis.
rdcu.be/d9iRG
rdcu.be/d9iRG
Reposted by Alice Burleigh
🚨 The European Animal Research Association has a vacancy for a Communications & social media officer position.
Find out more about how to apply below.
#jobhunt #jobopening #jobsearch #job #hiring #recruiting #commsjobs #scicomm #scicommjob #scicommjobs
www.eara.eu/post/job-vac...
Find out more about how to apply below.
#jobhunt #jobopening #jobsearch #job #hiring #recruiting #commsjobs #scicomm #scicommjob #scicommjobs
www.eara.eu/post/job-vac...
Job vacancy: Communications and Social Media Officer
Job Title: Communications and Social Media OfficerWorking For: European Animal Research AssociationLocation: London, with international travelSalary: This is a full-time position, salary £31,000–£35,0...
www.eara.eu
February 6, 2025 at 3:43 PM
🚨 The European Animal Research Association has a vacancy for a Communications & social media officer position.
Find out more about how to apply below.
#jobhunt #jobopening #jobsearch #job #hiring #recruiting #commsjobs #scicomm #scicommjob #scicommjobs
www.eara.eu/post/job-vac...
Find out more about how to apply below.
#jobhunt #jobopening #jobsearch #job #hiring #recruiting #commsjobs #scicomm #scicommjob #scicommjobs
www.eara.eu/post/job-vac...
Reposted by Alice Burleigh
📢Job opportunities!
We're looking for a Research Associate (Fixed Term) to join Dr Gavin Sewell on a research project investigating how #autoinflammatory conditions occur.
Apply by 14 February: https://buff.ly/4aBF8rW
@wellcometrust.bsky.social
@uniofcam.bsky.social
We're looking for a Research Associate (Fixed Term) to join Dr Gavin Sewell on a research project investigating how #autoinflammatory conditions occur.
Apply by 14 February: https://buff.ly/4aBF8rW
@wellcometrust.bsky.social
@uniofcam.bsky.social
Research Assistant (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant (Fixed Term) in the Department of Medicine at the University of Cambridge.
buff.ly
February 5, 2025 at 11:00 AM
📢Job opportunities!
We're looking for a Research Associate (Fixed Term) to join Dr Gavin Sewell on a research project investigating how #autoinflammatory conditions occur.
Apply by 14 February: https://buff.ly/4aBF8rW
@wellcometrust.bsky.social
@uniofcam.bsky.social
We're looking for a Research Associate (Fixed Term) to join Dr Gavin Sewell on a research project investigating how #autoinflammatory conditions occur.
Apply by 14 February: https://buff.ly/4aBF8rW
@wellcometrust.bsky.social
@uniofcam.bsky.social
Reposted by Alice Burleigh
What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)?
Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼
Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼
What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)?
A new study shows that some of our cells favor genes of one parent or the other and can explain a longstanding mystery of why some people with disease-causing genes experience no symptoms.
www.cuimc.columbia.edu
January 1, 2025 at 5:45 PM
What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)?
Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼
Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼
Reposted by Alice Burleigh
A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases.
Please let me know if you’d like to be added.
go.bsky.app/5M6obrp
Please let me know if you’d like to be added.
go.bsky.app/5M6obrp
December 7, 2024 at 2:10 AM
A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases.
Please let me know if you’d like to be added.
go.bsky.app/5M6obrp
Please let me know if you’d like to be added.
go.bsky.app/5M6obrp
Reposted by Alice Burleigh
🚨 A PhD project to develop an in vitro human implantation platform is available with me and an interdisciplinary supervisory team at the University of Sheffield.
#blastoids #endometrialAssembloids
#stemCellBiology #embryology #biomaterials #advancedImaging #dataScience
tinyurl.com/ycykmwv4
#blastoids #endometrialAssembloids
#stemCellBiology #embryology #biomaterials #advancedImaging #dataScience
tinyurl.com/ycykmwv4
November 28, 2024 at 12:46 AM
🚨 A PhD project to develop an in vitro human implantation platform is available with me and an interdisciplinary supervisory team at the University of Sheffield.
#blastoids #endometrialAssembloids
#stemCellBiology #embryology #biomaterials #advancedImaging #dataScience
tinyurl.com/ycykmwv4
#blastoids #endometrialAssembloids
#stemCellBiology #embryology #biomaterials #advancedImaging #dataScience
tinyurl.com/ycykmwv4
Reposted by Alice Burleigh
TANK and AZI2 cooperatively sustain TBK1 activity during different stages of TNF receptor assembly to protect against autoinflammation
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 20, 2024 at 11:07 PM
TANK and AZI2 cooperatively sustain TBK1 activity during different stages of TNF receptor assembly to protect against autoinflammation
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Alice Burleigh
www.nature.com/articles/s41...
“our findings demonstrate a general mechanism involving how self-RNA structure affect innate sensors-triggering innate response and autoinflammation, and provide a potential strategy for controlling TLR-related autoimmune diseases.”
#TLR7 #lupus #SLE
“our findings demonstrate a general mechanism involving how self-RNA structure affect innate sensors-triggering innate response and autoinflammation, and provide a potential strategy for controlling TLR-related autoimmune diseases.”
#TLR7 #lupus #SLE
Promotion of TLR7-MyD88-dependent inflammation and autoimmunity in mice through stem-loop changes in Lnc-Atg16l1 - Nature Communications
TLR7 has been shown to promote inflammatory autoimmunity. Here the authors investigate whether changes in RNA structure affect TLR signaling and show that a TLR7 binding lncRNA Lnc-Atg16l1 promotes de...
www.nature.com
November 27, 2024 at 1:14 PM
www.nature.com/articles/s41...
“our findings demonstrate a general mechanism involving how self-RNA structure affect innate sensors-triggering innate response and autoinflammation, and provide a potential strategy for controlling TLR-related autoimmune diseases.”
#TLR7 #lupus #SLE
“our findings demonstrate a general mechanism involving how self-RNA structure affect innate sensors-triggering innate response and autoinflammation, and provide a potential strategy for controlling TLR-related autoimmune diseases.”
#TLR7 #lupus #SLE
Reposted by Alice Burleigh
December 4, 2024 at 4:47 AM
Reposted by Alice Burleigh
Reposted by Alice Burleigh
I created a simple flow chart to help my lab trainees choose the most appropriate stats test in Prism (*for single-factor comparisons only). Feel free to share with your group if you think it could be helpful first start.
November 20, 2024 at 5:28 PM
I created a simple flow chart to help my lab trainees choose the most appropriate stats test in Prism (*for single-factor comparisons only). Feel free to share with your group if you think it could be helpful first start.
Reposted by Alice Burleigh
New starter pack for all people interested in Gene Editing & Gene Therapy 🧬✂️ including Tools & Delivery|CRISPR-Cas|Zinc finger nucleases|Viral vectors|Non-viral delivery methods
go.bsky.app/8R4dVez
go.bsky.app/8R4dVez
November 20, 2024 at 9:12 PM
New starter pack for all people interested in Gene Editing & Gene Therapy 🧬✂️ including Tools & Delivery|CRISPR-Cas|Zinc finger nucleases|Viral vectors|Non-viral delivery methods
go.bsky.app/8R4dVez
go.bsky.app/8R4dVez