Alexandru Stieber
@alexstieber.bsky.social
Internal Medicine resident | Passionate about rare diseases, rheumatology and neurology | Aspiring diagnostician
4/
➡️ low rate of diagnostic spenectomy (4.8%)
➡️ only 2% of pts had a diagnosis of lysosomal storage diseases (10/505)
➡️ low rate of diagnostic spenectomy (4.8%)
➡️ only 2% of pts had a diagnosis of lysosomal storage diseases (10/505)
August 15, 2025 at 3:54 PM
4/
➡️ low rate of diagnostic spenectomy (4.8%)
➡️ only 2% of pts had a diagnosis of lysosomal storage diseases (10/505)
➡️ low rate of diagnostic spenectomy (4.8%)
➡️ only 2% of pts had a diagnosis of lysosomal storage diseases (10/505)
3/
➡️ older age, massive splenomegaly, high platelets, high LDH levels, biopsy exploration, bone marrow exploration --> #myeloid malignancies
➡️ thrombocytopenia, abnormal y-GT levels, presence of a monoclonal peak, liver biopsy exploration --> portal hypertension
➡️ older age, massive splenomegaly, high platelets, high LDH levels, biopsy exploration, bone marrow exploration --> #myeloid malignancies
➡️ thrombocytopenia, abnormal y-GT levels, presence of a monoclonal peak, liver biopsy exploration --> portal hypertension
August 15, 2025 at 3:54 PM
3/
➡️ older age, massive splenomegaly, high platelets, high LDH levels, biopsy exploration, bone marrow exploration --> #myeloid malignancies
➡️ thrombocytopenia, abnormal y-GT levels, presence of a monoclonal peak, liver biopsy exploration --> portal hypertension
➡️ older age, massive splenomegaly, high platelets, high LDH levels, biopsy exploration, bone marrow exploration --> #myeloid malignancies
➡️ thrombocytopenia, abnormal y-GT levels, presence of a monoclonal peak, liver biopsy exploration --> portal hypertension
2/
➡️ hypogammaglobulinemia, massive splenomegaly (>18 cm), heterogeneous spleen, lymphocytosis, presence of a #monoclonal peak, older age at inclusion --> lymphoid malignancies ⚠️
➡️ high CRP, constitutional Sx, osteoarticular symptoms --> autoimmune/inflammatory diseases
➡️ hypogammaglobulinemia, massive splenomegaly (>18 cm), heterogeneous spleen, lymphocytosis, presence of a #monoclonal peak, older age at inclusion --> lymphoid malignancies ⚠️
➡️ high CRP, constitutional Sx, osteoarticular symptoms --> autoimmune/inflammatory diseases
August 15, 2025 at 3:54 PM
2/
➡️ hypogammaglobulinemia, massive splenomegaly (>18 cm), heterogeneous spleen, lymphocytosis, presence of a #monoclonal peak, older age at inclusion --> lymphoid malignancies ⚠️
➡️ high CRP, constitutional Sx, osteoarticular symptoms --> autoimmune/inflammatory diseases
➡️ hypogammaglobulinemia, massive splenomegaly (>18 cm), heterogeneous spleen, lymphocytosis, presence of a #monoclonal peak, older age at inclusion --> lymphoid malignancies ⚠️
➡️ high CRP, constitutional Sx, osteoarticular symptoms --> autoimmune/inflammatory diseases
1/
➡️ less than half of all patients in the cohort had a cause identified for their spleen enlargement
➡️ #lymphoid malignancies and #autoimmune/#inflammatory diseases were the most frequent etiologies in their respective categories (malignant vs non-malignant causes)
➡️ less than half of all patients in the cohort had a cause identified for their spleen enlargement
➡️ #lymphoid malignancies and #autoimmune/#inflammatory diseases were the most frequent etiologies in their respective categories (malignant vs non-malignant causes)
August 15, 2025 at 3:54 PM
1/
➡️ less than half of all patients in the cohort had a cause identified for their spleen enlargement
➡️ #lymphoid malignancies and #autoimmune/#inflammatory diseases were the most frequent etiologies in their respective categories (malignant vs non-malignant causes)
➡️ less than half of all patients in the cohort had a cause identified for their spleen enlargement
➡️ #lymphoid malignancies and #autoimmune/#inflammatory diseases were the most frequent etiologies in their respective categories (malignant vs non-malignant causes)
Always a pleasure sharing research in the field of autoinflammatory diseases!
March 27, 2025 at 9:48 PM
Always a pleasure sharing research in the field of autoinflammatory diseases!
Scientific work done right, with approval by the Gen Z ers 😂
March 16, 2025 at 9:32 PM
Scientific work done right, with approval by the Gen Z ers 😂