Alexandru Stieber
@alexstieber.bsky.social
Internal Medicine resident | Passionate about rare diseases, rheumatology and neurology | Aspiring diagnostician
Recent publication of the #SplenoMegaly study (SMS), with very interesting insights into the various etiologies and their possible predictive factors.
A short thread with the results 🧵
#medsky #rheumsky #hemesky
A short thread with the results 🧵
#medsky #rheumsky #hemesky
August 15, 2025 at 3:54 PM
Recent publication of the #SplenoMegaly study (SMS), with very interesting insights into the various etiologies and their possible predictive factors.
A short thread with the results 🧵
#medsky #rheumsky #hemesky
A short thread with the results 🧵
#medsky #rheumsky #hemesky
Important to acknowledge that #Mycoplasma infections go beyond atypical #pneumonia and should be included on the EM/SJS/TEN differential!! #dermsky #medsky #pneumosky
🔗 journal.chestnet.org/article/S001...
🔗 journal.chestnet.org/article/S001...
August 12, 2025 at 5:39 PM
Important to acknowledge that #Mycoplasma infections go beyond atypical #pneumonia and should be included on the EM/SJS/TEN differential!! #dermsky #medsky #pneumosky
🔗 journal.chestnet.org/article/S001...
🔗 journal.chestnet.org/article/S001...
A great overview of inborn errors of #immunity with #atopic phenotypes (IElwA) highlighting the main entities included in this category, such as Hyper-IgE syndromes, #IPEX and Wiskott-Aldrich syndrome, and the major red flags that should lead clinicians to consider these primary atopic disorders.
August 8, 2025 at 5:20 PM
Further discussions on the role #upadacitinib will likely play in the therapeutic landscape of #giantcellarteritis treatment.
#medsky #rheumsky
🔗https://www.sciencedirect.com/science/article/abs/pii/S0248866325006265?via%3Dihub
#medsky #rheumsky
🔗https://www.sciencedirect.com/science/article/abs/pii/S0248866325006265?via%3Dihub
July 8, 2025 at 9:48 AM
Further discussions on the role #upadacitinib will likely play in the therapeutic landscape of #giantcellarteritis treatment.
#medsky #rheumsky
🔗https://www.sciencedirect.com/science/article/abs/pii/S0248866325006265?via%3Dihub
#medsky #rheumsky
🔗https://www.sciencedirect.com/science/article/abs/pii/S0248866325006265?via%3Dihub
Rare occurence of cutaneous hemosiderin deposits in the context of secondary #hemochromatosis due to metabolic dysfunction.
#medsky #hyperferritinemia
🔗https://www.ejinme.com/article/S0953-6205(25)00121-9/fulltext
#medsky #hyperferritinemia
🔗https://www.ejinme.com/article/S0953-6205(25)00121-9/fulltext
June 11, 2025 at 4:05 PM
Rare occurence of cutaneous hemosiderin deposits in the context of secondary #hemochromatosis due to metabolic dysfunction.
#medsky #hyperferritinemia
🔗https://www.ejinme.com/article/S0953-6205(25)00121-9/fulltext
#medsky #hyperferritinemia
🔗https://www.ejinme.com/article/S0953-6205(25)00121-9/fulltext
Key points from #ISSAID2025
This #autoinflammatory disease congress wouldn't have been complete without some updates on #VEXAS syndrome:
- new "VEXAS man" schema, with updated manifestations
- better defined risk factors for a worse prognosis
- VEXAS-like syndromes DO exist!!
#rheumsky #medsky
This #autoinflammatory disease congress wouldn't have been complete without some updates on #VEXAS syndrome:
- new "VEXAS man" schema, with updated manifestations
- better defined risk factors for a worse prognosis
- VEXAS-like syndromes DO exist!!
#rheumsky #medsky
April 19, 2025 at 11:02 AM
Key points from #ISSAID2025
This #autoinflammatory disease congress wouldn't have been complete without some updates on #VEXAS syndrome:
- new "VEXAS man" schema, with updated manifestations
- better defined risk factors for a worse prognosis
- VEXAS-like syndromes DO exist!!
#rheumsky #medsky
This #autoinflammatory disease congress wouldn't have been complete without some updates on #VEXAS syndrome:
- new "VEXAS man" schema, with updated manifestations
- better defined risk factors for a worse prognosis
- VEXAS-like syndromes DO exist!!
#rheumsky #medsky
Romanian team at #ISSAID2025 with our posters on:
➡️ RO_FMF study: patients with MEFV mutations (mostly heterozygous mutations and mild phenotypes)
➡️ case series of Romanian patients with NOD2 mutations and their clinical phenotypes
#autoinflammatory #rheumsky
➡️ RO_FMF study: patients with MEFV mutations (mostly heterozygous mutations and mild phenotypes)
➡️ case series of Romanian patients with NOD2 mutations and their clinical phenotypes
#autoinflammatory #rheumsky
April 10, 2025 at 9:30 AM
Romanian team at #ISSAID2025 with our posters on:
➡️ RO_FMF study: patients with MEFV mutations (mostly heterozygous mutations and mild phenotypes)
➡️ case series of Romanian patients with NOD2 mutations and their clinical phenotypes
#autoinflammatory #rheumsky
➡️ RO_FMF study: patients with MEFV mutations (mostly heterozygous mutations and mild phenotypes)
➡️ case series of Romanian patients with NOD2 mutations and their clinical phenotypes
#autoinflammatory #rheumsky
What to do about pts with lymphadenopathies and histology suggestive for #Castleman? More info in this article, delineating a possibly early stage of iMCD: ⚠️asymptomatic MCD⚠️ #medsky #hemesky
ashpublications.org/bloodadvance...
ashpublications.org/bloodadvance...
March 17, 2025 at 9:27 AM
What to do about pts with lymphadenopathies and histology suggestive for #Castleman? More info in this article, delineating a possibly early stage of iMCD: ⚠️asymptomatic MCD⚠️ #medsky #hemesky
ashpublications.org/bloodadvance...
ashpublications.org/bloodadvance...
Latest diagnosis and treatment recommendations for chronic non-bacterial osteitis #rheumsky #CNO #SAPHO #axSpA
ard.bmj.com/content/earl...
ard.bmj.com/content/earl...
March 12, 2025 at 8:57 PM
Latest diagnosis and treatment recommendations for chronic non-bacterial osteitis #rheumsky #CNO #SAPHO #axSpA
ard.bmj.com/content/earl...
ard.bmj.com/content/earl...
Work-up in suspected PMR patients
via @acr-journals.bsky.social and @medscape.com
#medsky #rheumsky #polymyalgiarheumatica
via @acr-journals.bsky.social and @medscape.com
#medsky #rheumsky #polymyalgiarheumatica
March 12, 2025 at 6:39 AM
Work-up in suspected PMR patients
via @acr-journals.bsky.social and @medscape.com
#medsky #rheumsky #polymyalgiarheumatica
via @acr-journals.bsky.social and @medscape.com
#medsky #rheumsky #polymyalgiarheumatica
March 10, 2025 at 5:10 PM
Brief presentation of the international cohort of SOCS1 insufficiency patients, autoimmune lymphoproliferative disease distinguished by frequent rheumatological and atopic manifestations.
#medsky #rheumsky #allergysky
www.thelancet.com/journals/lan...
#medsky #rheumsky #allergysky
www.thelancet.com/journals/lan...
March 7, 2025 at 6:02 PM
Brief presentation of the international cohort of SOCS1 insufficiency patients, autoimmune lymphoproliferative disease distinguished by frequent rheumatological and atopic manifestations.
#medsky #rheumsky #allergysky
www.thelancet.com/journals/lan...
#medsky #rheumsky #allergysky
www.thelancet.com/journals/lan...
Deep dive into #SAPHO syndrome and the related #autoinflammatory diseases
#medsky #rheumsky
link.springer.com/article/10.1...
#medsky #rheumsky
link.springer.com/article/10.1...
February 24, 2025 at 9:05 PM
Deep dive into #SAPHO syndrome and the related #autoinflammatory diseases
#medsky #rheumsky
link.springer.com/article/10.1...
#medsky #rheumsky
link.springer.com/article/10.1...
February 19, 2025 at 6:49 PM
February 10, 2025 at 6:06 PM
Main differences between the main histiocytic disorders
via @Arthritis Care & Research
#medsky #hemsky #histiocytosis
@acr-journals.bsky.social
via @Arthritis Care & Research
#medsky #hemsky #histiocytosis
@acr-journals.bsky.social
February 8, 2025 at 2:45 PM
Main differences between the main histiocytic disorders
via @Arthritis Care & Research
#medsky #hemsky #histiocytosis
@acr-journals.bsky.social
via @Arthritis Care & Research
#medsky #hemsky #histiocytosis
@acr-journals.bsky.social
Well-Established Monogenic Causes of Cerebral Small Vessel Disease via @greenjournal.bsky.social
#neurosky
#neurosky
February 6, 2025 at 4:30 PM
Well-Established Monogenic Causes of Cerebral Small Vessel Disease via @greenjournal.bsky.social
#neurosky
#neurosky
February 5, 2025 at 8:31 PM
Really great review, as usual!
As an extra tidbit, when you spot the Eiffel Tower on scans, think hypertrophic pachymeningitis.
#neurosky
As an extra tidbit, when you spot the Eiffel Tower on scans, think hypertrophic pachymeningitis.
#neurosky
January 30, 2025 at 12:18 AM
Really great review, as usual!
As an extra tidbit, when you spot the Eiffel Tower on scans, think hypertrophic pachymeningitis.
#neurosky
As an extra tidbit, when you spot the Eiffel Tower on scans, think hypertrophic pachymeningitis.
#neurosky
- GI manifestations are still the main clinical presentation of #celiacdisease
HOWEVER
- clinicians should keep in mind the plethora of extraintestinal manifestations of CD + frequent association with other autoimmune disorders
⬇️⬇️
doi.org/10.1007/s117...
#GIsky #Gastrosky
HOWEVER
- clinicians should keep in mind the plethora of extraintestinal manifestations of CD + frequent association with other autoimmune disorders
⬇️⬇️
doi.org/10.1007/s117...
#GIsky #Gastrosky
January 29, 2025 at 7:47 PM
- GI manifestations are still the main clinical presentation of #celiacdisease
HOWEVER
- clinicians should keep in mind the plethora of extraintestinal manifestations of CD + frequent association with other autoimmune disorders
⬇️⬇️
doi.org/10.1007/s117...
#GIsky #Gastrosky
HOWEVER
- clinicians should keep in mind the plethora of extraintestinal manifestations of CD + frequent association with other autoimmune disorders
⬇️⬇️
doi.org/10.1007/s117...
#GIsky #Gastrosky
A better look at vitamin B12 metabolism and all its intricacies
#MedSky @bloodjournal.bsky.social
t.co/N8GTxx4QF6
#MedSky @bloodjournal.bsky.social
t.co/N8GTxx4QF6
January 28, 2025 at 11:34 PM
A better look at vitamin B12 metabolism and all its intricacies
#MedSky @bloodjournal.bsky.social
t.co/N8GTxx4QF6
#MedSky @bloodjournal.bsky.social
t.co/N8GTxx4QF6