Alessandro Matera
@ale-matera.bsky.social
Neurobiologist. I am interested in macrophages, neurons and brain tumor microenvironment. Postdoc in Prof. Joyce’s laboratory, University of Lausanne.
Pinned
Alessandro Matera
@ale-matera.bsky.social
· Jan 14
New issue online! Cover depicts work from Rosa Paolicelli
@ale-matera.bsky.social AnneCompagnion &co showing that Inpp5d (SHIP1) is expressed in microglia during early postnatal brain development, where it limits synaptic pruning in a complement-dependent manner www.cell.com/immunity/iss...
@ale-matera.bsky.social AnneCompagnion &co showing that Inpp5d (SHIP1) is expressed in microglia during early postnatal brain development, where it limits synaptic pruning in a complement-dependent manner www.cell.com/immunity/iss...
Excited to see the new issue of @cp-immunity.bsky.social, with our cover 😍 RosaChiaraPaolicelli & Anne-ClaireCompagnion
Reposted by Alessandro Matera
Celebrating our annual international lab dinner 🎉 👨🏽🍳 🧑🏻🍳
We are so fortunate to have this amazing team of motivated scientists, and very talented cooks 🤩 sharing delicious food & culture from around the world 🌍🌎🌏
Grateful for our #international #team 🇮🇹🇫🇷🇨🇦🇪🇸🇨🇭🇬🇧🇪🇬🇩🇪🇵🇹🇲🇽🇮🇪 - this truly enriches our science 🙏 🙌
We are so fortunate to have this amazing team of motivated scientists, and very talented cooks 🤩 sharing delicious food & culture from around the world 🌍🌎🌏
Grateful for our #international #team 🇮🇹🇫🇷🇨🇦🇪🇸🇨🇭🇬🇧🇪🇬🇩🇪🇵🇹🇲🇽🇮🇪 - this truly enriches our science 🙏 🙌
September 25, 2025 at 1:46 PM
Celebrating our annual international lab dinner 🎉 👨🏽🍳 🧑🏻🍳
We are so fortunate to have this amazing team of motivated scientists, and very talented cooks 🤩 sharing delicious food & culture from around the world 🌍🌎🌏
Grateful for our #international #team 🇮🇹🇫🇷🇨🇦🇪🇸🇨🇭🇬🇧🇪🇬🇩🇪🇵🇹🇲🇽🇮🇪 - this truly enriches our science 🙏 🙌
We are so fortunate to have this amazing team of motivated scientists, and very talented cooks 🤩 sharing delicious food & culture from around the world 🌍🌎🌏
Grateful for our #international #team 🇮🇹🇫🇷🇨🇦🇪🇸🇨🇭🇬🇧🇪🇬🇩🇪🇵🇹🇲🇽🇮🇪 - this truly enriches our science 🙏 🙌
Reposted by Alessandro Matera
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
September 3, 2025 at 12:56 PM
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
A conference that will explore how the involvement of cancer advocates can lead to impactful cancer research. Do not miss it!
How can patients help shape the future of cancer research?
Join us at our new virtual conference to explore how involving cancer patients in research leads to more meaningful, impactful outcomes.
Learn more and register: eacr.org/conference/p...
Join us at our new virtual conference to explore how involving cancer patients in research leads to more meaningful, impactful outcomes.
Learn more and register: eacr.org/conference/p...
August 5, 2025 at 2:53 PM
A conference that will explore how the involvement of cancer advocates can lead to impactful cancer research. Do not miss it!
Reposted by Alessandro Matera
EACR-@themarkfdn.bsky.social Postdoctoral Fellowships are awarded for a period of three years and support excellent postdoctoral researchers in laboratories throughout Europe. Is that you?
Apply by 20 August: eacr.org/eacr-fellows...
Apply by 20 August: eacr.org/eacr-fellows...
July 15, 2025 at 8:01 AM
EACR-@themarkfdn.bsky.social Postdoctoral Fellowships are awarded for a period of three years and support excellent postdoctoral researchers in laboratories throughout Europe. Is that you?
Apply by 20 August: eacr.org/eacr-fellows...
Apply by 20 August: eacr.org/eacr-fellows...
In vitro assay for #microglial #engulfment and #degradation of #synaptosomes in fixed and live samples, using #confocal imaging. Curious how it works? Check out our article (@ACCompagnion and @paolicellilab.bsky.social) in @cp-starprotocols.bsky.social.
star-protocols.cell.com/protocols/4321
star-protocols.cell.com/protocols/4321
Cell Press: STAR Protocols
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...
star-protocols.cell.com
July 14, 2025 at 1:08 PM
In vitro assay for #microglial #engulfment and #degradation of #synaptosomes in fixed and live samples, using #confocal imaging. Curious how it works? Check out our article (@ACCompagnion and @paolicellilab.bsky.social) in @cp-starprotocols.bsky.social.
star-protocols.cell.com/protocols/4321
star-protocols.cell.com/protocols/4321
Reposted by Alessandro Matera
Have you submitted your abstract for Cancer Neuroscience yet? You still have one month left to take advantage of this fantastic opportunity to showcase your own research and explore this exciting and rapidly evolving topic with international leaders of the field.
eacr.org/conference/c...
eacr.org/conference/c...
May 30, 2025 at 8:01 AM
Have you submitted your abstract for Cancer Neuroscience yet? You still have one month left to take advantage of this fantastic opportunity to showcase your own research and explore this exciting and rapidly evolving topic with international leaders of the field.
eacr.org/conference/c...
eacr.org/conference/c...
Reposted by Alessandro Matera
Wishing our amazing postdoc @lbejarano.bsky.social continued success and happiness - as she leaves us to start her own lab in Spain 🎉🥳
Leire has been one of the most positive, creative, and kind scientists I've had the privilege to mentor - we shall all miss you so much!
#NewPI 🤩
#ProudMentor 😊
Leire has been one of the most positive, creative, and kind scientists I've had the privilege to mentor - we shall all miss you so much!
#NewPI 🤩
#ProudMentor 😊
May 27, 2025 at 6:07 PM
Wishing our amazing postdoc @lbejarano.bsky.social continued success and happiness - as she leaves us to start her own lab in Spain 🎉🥳
Leire has been one of the most positive, creative, and kind scientists I've had the privilege to mentor - we shall all miss you so much!
#NewPI 🤩
#ProudMentor 😊
Leire has been one of the most positive, creative, and kind scientists I've had the privilege to mentor - we shall all miss you so much!
#NewPI 🤩
#ProudMentor 😊
Interested in learning more about cancer models that span in vitro investigations to in vivo cancer biology? Join the EACR in Essen, from 23-25 Sept 2025 for Goodbye Flat Biology! 🔬🧪 #CancerResearch #Oncology
After a sold-out 2023 event, Goodbye Flat Biology has moved to a larger venue in Essen, Germany to make sure more of you can join us for what promises to be another fantastic event!
Join us for 3 days of excellent science and networking:
eacr.org/conference/g...
Join us for 3 days of excellent science and networking:
eacr.org/conference/g...
April 15, 2025 at 3:08 PM
Interested in learning more about cancer models that span in vitro investigations to in vivo cancer biology? Join the EACR in Essen, from 23-25 Sept 2025 for Goodbye Flat Biology! 🔬🧪 #CancerResearch #Oncology
Reposted by Alessandro Matera
Why do brain metastases resist #immunotherapy — even when the same cancer responds outside the #brain? 🧠🧪💥
We just published a study diving into this question ⏬
Led by an amazing (former) PhD student in my lab —Vladimir Wischnewski 🎉
🧵 1/
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
We just published a study diving into this question ⏬
Led by an amazing (former) PhD student in my lab —Vladimir Wischnewski 🎉
🧵 1/
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
March 31, 2025 at 12:20 PM
Why do brain metastases resist #immunotherapy — even when the same cancer responds outside the #brain? 🧠🧪💥
We just published a study diving into this question ⏬
Led by an amazing (former) PhD student in my lab —Vladimir Wischnewski 🎉
🧵 1/
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
We just published a study diving into this question ⏬
Led by an amazing (former) PhD student in my lab —Vladimir Wischnewski 🎉
🧵 1/
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
Reposted by Alessandro Matera
We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪
www.nature.com/articles/d41...
www.nature.com/articles/d41...
75% of US scientists who answered Nature poll consider leaving
More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.
www.nature.com
March 27, 2025 at 2:19 PM
We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Alessandro Matera
Thrilled to see our vascular atlas across primary and metastatic brain tumors finally out in Immunity! 😍 🍾
Thanks to @johannajoyce.bsky.social for her invaluable mentorship and to all the authors involved! 🎉
Thanks to @johannajoyce.bsky.social for her invaluable mentorship and to all the authors involved! 🎉
Online now: Single-cell atlas of endothelial and mural cells across primary and metastatic brain tumors
Single-cell atlas of endothelial and mural cells across primary and metastatic brain tumors
Central nervous system malignancies include primary tumors and brain metastases (BrMs) originating from extracranial cancers. Bejarano et al. examine primary and metastatic brain tumors and find distinct vascular alterations in IDH mutant gliomas, IDH WT…
dlvr.it
March 20, 2025 at 10:12 AM
Thrilled to see our vascular atlas across primary and metastatic brain tumors finally out in Immunity! 😍 🍾
Thanks to @johannajoyce.bsky.social for her invaluable mentorship and to all the authors involved! 🎉
Thanks to @johannajoyce.bsky.social for her invaluable mentorship and to all the authors involved! 🎉
Reposted by Alessandro Matera
How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
March 20, 2025 at 1:51 PM
How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Reposted by Alessandro Matera
Well done to the first recipients of the EACR-Mark Foundation postdoc fellowships 🎉🎊
And a happy coincidence that all three awardees are women scientists in the labs of three women PIs 🙌
#WomeninSTEM #WomeninScience 👩🔬👩🏻🔬🧪
@themarkfdn.bsky.social
@helloeacr.bsky.social
@juliemmazet.bsky.social
And a happy coincidence that all three awardees are women scientists in the labs of three women PIs 🙌
#WomeninSTEM #WomeninScience 👩🔬👩🏻🔬🧪
@themarkfdn.bsky.social
@helloeacr.bsky.social
@juliemmazet.bsky.social
Congratulations to our first EACR-@themarkfdn Postdoctoral Fellowship winners! Julie Mazet, Christina Metoikidou and Martha Zarou 👏
This funding is awarded for a period of three years to support excellent postdoctoral researchers in laboratories throughout Europe.
magazine.eacr.org/congratulati...
This funding is awarded for a period of three years to support excellent postdoctoral researchers in laboratories throughout Europe.
magazine.eacr.org/congratulati...
March 19, 2025 at 10:33 AM
Well done to the first recipients of the EACR-Mark Foundation postdoc fellowships 🎉🎊
And a happy coincidence that all three awardees are women scientists in the labs of three women PIs 🙌
#WomeninSTEM #WomeninScience 👩🔬👩🏻🔬🧪
@themarkfdn.bsky.social
@helloeacr.bsky.social
@juliemmazet.bsky.social
And a happy coincidence that all three awardees are women scientists in the labs of three women PIs 🙌
#WomeninSTEM #WomeninScience 👩🔬👩🏻🔬🧪
@themarkfdn.bsky.social
@helloeacr.bsky.social
@juliemmazet.bsky.social
Reposted by Alessandro Matera
The EACR stands against threats to cancer research. Protecting scientific research is vital for progress and and the development of new treatments. Read our full statement in support of our friends and colleagues in the US: eacr.org/statement-on...
March 10, 2025 at 12:02 PM
The EACR stands against threats to cancer research. Protecting scientific research is vital for progress and and the development of new treatments. Read our full statement in support of our friends and colleagues in the US: eacr.org/statement-on...
Reposted by Alessandro Matera
Women in research need the credit & recognition they deserve for the amazing contributions they make.
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards Inspiring Women in Science
Celebrating and supporting the achievements of women in science, and all those who work to encourage girls and young women to engage with STEM subjects and stay in STEM careers around the world.
www.nature.com
March 8, 2025 at 8:24 AM
Women in research need the credit & recognition they deserve for the amazing contributions they make.
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Excited to see the new issue of @cp-immunity.bsky.social, with our cover 😍 RosaChiaraPaolicelli & Anne-ClaireCompagnion
New issue online! Cover depicts work from Rosa Paolicelli
@ale-matera.bsky.social AnneCompagnion &co showing that Inpp5d (SHIP1) is expressed in microglia during early postnatal brain development, where it limits synaptic pruning in a complement-dependent manner www.cell.com/immunity/iss...
@ale-matera.bsky.social AnneCompagnion &co showing that Inpp5d (SHIP1) is expressed in microglia during early postnatal brain development, where it limits synaptic pruning in a complement-dependent manner www.cell.com/immunity/iss...
January 14, 2025 at 6:11 PM
Excited to see the new issue of @cp-immunity.bsky.social, with our cover 😍 RosaChiaraPaolicelli & Anne-ClaireCompagnion
Reposted by Alessandro Matera
#50ScientistsThatInspire 🧪
A collection created by @cellpress.bsky.social for #Cell50 🎉
Including inspiring #scientists and committed #advocates in their communities 🙌
In this 🧵 I'll share some of the interviews - including this Q&A we did 👇
Its an honor to be part of this incredible list 🙏 🙏
A collection created by @cellpress.bsky.social for #Cell50 🎉
Including inspiring #scientists and committed #advocates in their communities 🙌
In this 🧵 I'll share some of the interviews - including this Q&A we did 👇
Its an honor to be part of this incredible list 🙏 🙏
For cancer biologist Johanna Joyce, teaching is essential to being a well-rounded scientist
Advice on finding a supportive academic environment, building inclusivity in science, tackling scientific problems with an open mind, and more from Dr. Joyce.
www.cell.com
December 11, 2024 at 2:11 PM
#50ScientistsThatInspire 🧪
A collection created by @cellpress.bsky.social for #Cell50 🎉
Including inspiring #scientists and committed #advocates in their communities 🙌
In this 🧵 I'll share some of the interviews - including this Q&A we did 👇
Its an honor to be part of this incredible list 🙏 🙏
A collection created by @cellpress.bsky.social for #Cell50 🎉
Including inspiring #scientists and committed #advocates in their communities 🙌
In this 🧵 I'll share some of the interviews - including this Q&A we did 👇
Its an honor to be part of this incredible list 🙏 🙏
Thrilled to share this article, which was the main work of my Ph.D. thesis, about the role of #SHIP1 as a modulator of #microglia function in early #brain #development. Special thanks to @rosa_paolicelli, @AnneCompagnion, and all the co-authors!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
The gene inositol polyphosphate-5-phosphatase D (INPP5D), which encodes the lipid phosphatase SH2-containing inositol polyphosphate 5-phosphatase 1 (S…
www.sciencedirect.com
December 9, 2024 at 8:14 PM
Thrilled to share this article, which was the main work of my Ph.D. thesis, about the role of #SHIP1 as a modulator of #microglia function in early #brain #development. Special thanks to @rosa_paolicelli, @AnneCompagnion, and all the co-authors!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
To a fantastic new year with a wonderful team 🥂
Happy holidays!! 🎄
Happy holidays!! 🎄
Celebrating the start of the holiday season with our wonderful lab 🎄🎅 🎁
Grateful for this incredible, fun team - and a great year of science together 🤩🙏
Happy holidays!! 🌟🥂❄️🎉
Grateful for this incredible, fun team - and a great year of science together 🤩🙏
Happy holidays!! 🌟🥂❄️🎉
December 9, 2024 at 9:13 AM
To a fantastic new year with a wonderful team 🥂
Happy holidays!! 🎄
Happy holidays!! 🎄
Reposted by Alessandro Matera
I’m thrilled to announce that I will lead the Translational Cancer Immunogenomics lab at the @LIH_Luxembourg ! 🥳🥳🥳
We’re looking for an experienced technician, if you’re interested in #braincancer, #immunology and/or #genomics, please apply below! 🧬
t.co/Zre89d8BMr
We’re looking for an experienced technician, if you’re interested in #braincancer, #immunology and/or #genomics, please apply below! 🧬
t.co/Zre89d8BMr
https://tinyurl.com/2txh8dh5
t.co
November 16, 2024 at 8:39 AM
I’m thrilled to announce that I will lead the Translational Cancer Immunogenomics lab at the @LIH_Luxembourg ! 🥳🥳🥳
We’re looking for an experienced technician, if you’re interested in #braincancer, #immunology and/or #genomics, please apply below! 🧬
t.co/Zre89d8BMr
We’re looking for an experienced technician, if you’re interested in #braincancer, #immunology and/or #genomics, please apply below! 🧬
t.co/Zre89d8BMr
Reposted by Alessandro Matera
Hi friends 👋
We are a lab of curious researchers - dedicated to understanding and ultimately helping treat cancer
Our lab is led by Johanna Joyce, and we are students, postdocs & technicians from all over the world
🇮🇪🇨🇭🇪🇸🇫🇷🇵🇹🇮🇹🇨🇦🇲🇽🇪🇬🇬🇧🇩🇪
We love doing science 🧪🔬 and living in beautiful Lausanne, Switzerland!
We are a lab of curious researchers - dedicated to understanding and ultimately helping treat cancer
Our lab is led by Johanna Joyce, and we are students, postdocs & technicians from all over the world
🇮🇪🇨🇭🇪🇸🇫🇷🇵🇹🇮🇹🇨🇦🇲🇽🇪🇬🇬🇧🇩🇪
We love doing science 🧪🔬 and living in beautiful Lausanne, Switzerland!
November 17, 2024 at 9:32 AM
Hi friends 👋
We are a lab of curious researchers - dedicated to understanding and ultimately helping treat cancer
Our lab is led by Johanna Joyce, and we are students, postdocs & technicians from all over the world
🇮🇪🇨🇭🇪🇸🇫🇷🇵🇹🇮🇹🇨🇦🇲🇽🇪🇬🇬🇧🇩🇪
We love doing science 🧪🔬 and living in beautiful Lausanne, Switzerland!
We are a lab of curious researchers - dedicated to understanding and ultimately helping treat cancer
Our lab is led by Johanna Joyce, and we are students, postdocs & technicians from all over the world
🇮🇪🇨🇭🇪🇸🇫🇷🇵🇹🇮🇹🇨🇦🇲🇽🇪🇬🇬🇧🇩🇪
We love doing science 🧪🔬 and living in beautiful Lausanne, Switzerland!