Ángel Álvarez-Prado
@alvarezprado.bsky.social
Group Leader at LIH | Translational Cancer Immunogenomics Lab #cancer #immunology #genomics #openscience
Pinned
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
I’m beyond thrilled to announce that we’ve been awarded the ERC Starting Grant! 🥳🥳🥳
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
Reposted by Ángel Álvarez-Prado
Yet another great reason to live in Europe!!
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
November 10, 2025 at 7:51 PM
Yet another great reason to live in Europe!!
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Reposted by Ángel Álvarez-Prado
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
October 16, 2025 at 8:07 AM
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Super interesting, congrats Cristian and co-authors! 🤩
So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
dx.doi.org/10.1111/imr.70063
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...
dx.doi.org
September 25, 2025 at 8:49 PM
Super interesting, congrats Cristian and co-authors! 🤩
Reposted by Ángel Álvarez-Prado
So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
dx.doi.org/10.1111/imr.70063
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...
dx.doi.org
September 25, 2025 at 7:12 PM
So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
dx.doi.org/10.1111/imr.70063
Reposted by Ángel Álvarez-Prado
A team led by Ludwig Lausanne’s @johannajoyce.bsky.social & former postdoc @alvarezprado.bsky.social reports a potential drug target whose loss in certain GBM cells triggers antiviral alarms to stall cell proliferation & makes GBM tumors in mice more amenable to anti-cancer immunity.
bit.ly/4nhZ7Bj
bit.ly/4nhZ7Bj
September 23, 2025 at 5:21 PM
A team led by Ludwig Lausanne’s @johannajoyce.bsky.social & former postdoc @alvarezprado.bsky.social reports a potential drug target whose loss in certain GBM cells triggers antiviral alarms to stall cell proliferation & makes GBM tumors in mice more amenable to anti-cancer immunity.
bit.ly/4nhZ7Bj
bit.ly/4nhZ7Bj
Reposted by Ángel Álvarez-Prado
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."
September 7, 2025 at 8:04 PM
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."
I’m beyond thrilled to announce that we’ve been awarded the ERC Starting Grant! 🥳🥳🥳
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 4, 2025 at 10:41 AM
I’m beyond thrilled to announce that we’ve been awarded the ERC Starting Grant! 🥳🥳🥳
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠
Let’s go! 🤩
#ERCStG #Ageing #Immunogenomics #BrainMetastasis
Reposted by Ángel Álvarez-Prado
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
September 3, 2025 at 12:56 PM
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Can we exploit anti-viral immunity to treat brain cancer? 🦠 🧠
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival
Álvarez-Prado et al. report that targeting ADAR1 triggers cancer-cell-intrinsic anti-proliferative
mechanisms and fosters anti-tumoral immune responses, blocking tumor growth and extending
survival in...
www.cell.com
September 3, 2025 at 9:34 AM
Can we exploit anti-viral immunity to treat brain cancer? 🦠 🧠
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Reposted by Ángel Álvarez-Prado
Great technique from my @crick.ac.uk colleagues in @petrznam.bsky.social lab
Reconstructing neural circuits with barcoded Rabies virus & in situ sequencing
www.biorxiv.org/content/10.1...
Reconstructing neural circuits with barcoded Rabies virus & in situ sequencing
www.biorxiv.org/content/10.1...
Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits
Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...
www.biorxiv.org
July 21, 2025 at 6:23 AM
Great technique from my @crick.ac.uk colleagues in @petrznam.bsky.social lab
Reconstructing neural circuits with barcoded Rabies virus & in situ sequencing
www.biorxiv.org/content/10.1...
Reconstructing neural circuits with barcoded Rabies virus & in situ sequencing
www.biorxiv.org/content/10.1...
Reposted by Ángel Álvarez-Prado
What a wonderful week we’ve had here together in Lisbon for #EACR2025! Thank you to everyone who attended, presented at and helped organise this fantastic event. Sign up here for updates about EACR 2026 in Budapest… 👀 eacr.us5.list-manage.com/subscribe?u=...
June 19, 2025 at 1:08 PM
What a wonderful week we’ve had here together in Lisbon for #EACR2025! Thank you to everyone who attended, presented at and helped organise this fantastic event. Sign up here for updates about EACR 2026 in Budapest… 👀 eacr.us5.list-manage.com/subscribe?u=...
Good to have some measurable readouts supporting something which was already obvious… #mass_surveillance #AI #computer-vision
A paper in Nature suggests that computer-vision research is increasingly contributing to the development of surveillance technology. go.nature.com/4l6tRV2 🧪
June 25, 2025 at 10:15 PM
Good to have some measurable readouts supporting something which was already obvious… #mass_surveillance #AI #computer-vision
Reposted by Ángel Álvarez-Prado
90% of doing science is being open to new ideas.
May 31, 2025 at 6:14 PM
90% of doing science is being open to new ideas.
Yet another reason to rethink the current publication system towards an alternative which prioritises publishing reliable science over profit, protects scientists and their research and values the work we all do to communicate new knowledge. We can, but do we want to? www.nature.com/articles/d41...
Invasion of the ‘journal snatchers’: the firms that buy science publications and turn them rogue
Study finds dozens of journals that have hiked their fees and started churning out papers after being acquired by small, recently formed companies.
www.nature.com
April 21, 2025 at 7:32 PM
Yet another reason to rethink the current publication system towards an alternative which prioritises publishing reliable science over profit, protects scientists and their research and values the work we all do to communicate new knowledge. We can, but do we want to? www.nature.com/articles/d41...
Reposted by Ángel Álvarez-Prado
Excited to see our image on the cover of #Immunity today 🤩
Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study
www.cell.com/immunity/ful...
Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪
@cp-immunity.bsky.social
Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study
www.cell.com/immunity/ful...
Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪
@cp-immunity.bsky.social
April 8, 2025 at 2:50 PM
Excited to see our image on the cover of #Immunity today 🤩
Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study
www.cell.com/immunity/ful...
Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪
@cp-immunity.bsky.social
Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study
www.cell.com/immunity/ful...
Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪
@cp-immunity.bsky.social
Reposted by Ángel Álvarez-Prado
@contracancerinv.bsky.social: GRACIASx27000 (récord de registro en la XII Carrera hoy en Madrid), aunque ese número debería de multiplicarse por muchísimos miles más, por la cantidad innumerable de personas con cáncer y de investigadores/as que se benefician de vuestro apoyo. Un abrazo muy fuerte!
💙
💙
March 30, 2025 at 3:45 PM
@contracancerinv.bsky.social: GRACIASx27000 (récord de registro en la XII Carrera hoy en Madrid), aunque ese número debería de multiplicarse por muchísimos miles más, por la cantidad innumerable de personas con cáncer y de investigadores/as que se benefician de vuestro apoyo. Un abrazo muy fuerte!
💙
💙
Nice run through the beautiful forest of Strassen to contribute to the non-stop 24h race of the LIH team for #Relais2025Lux Together against #cancer, let’s go team!! 🔥
March 22, 2025 at 1:22 PM
Nice run through the beautiful forest of Strassen to contribute to the non-stop 24h race of the LIH team for #Relais2025Lux Together against #cancer, let’s go team!! 🔥
Reposted by Ángel Álvarez-Prado
How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
March 20, 2025 at 1:51 PM
How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻
🧵
@cp-immunity.bsky.social
www.cell.com/immunity/ful...
Extraordinary resource for the #brain_cancer community from @johannajoyce.bsky.social lab, led by the equally extraordinary @lbejarano.bsky.social, so happy to see this out! 👏 👏 👏
Researchers led by Ludwig @fbm-unil.bsky.social’s
@lbejarano.bsky.social & @johannajoyce.bsky.social analyzed individual cells of the blood-brain barrier across brain tissue, primary brain tumors & brain metastases, creating a vascular atlas to guide the design of new therapies.
bit.ly/4bFqwYY
@lbejarano.bsky.social & @johannajoyce.bsky.social analyzed individual cells of the blood-brain barrier across brain tissue, primary brain tumors & brain metastases, creating a vascular atlas to guide the design of new therapies.
bit.ly/4bFqwYY
March 19, 2025 at 7:17 PM
Extraordinary resource for the #brain_cancer community from @johannajoyce.bsky.social lab, led by the equally extraordinary @lbejarano.bsky.social, so happy to see this out! 👏 👏 👏
This wouldn’t have been possible without the support of the @braintumourcharity.bsky.social, they’re doing a fantastic job helping not only us scientists, but also patients and families ❤️
Thank you! 🙏
Thank you! 🙏
Researcher Dr @alvarezprado.bsky.social, one of our Future Leaders' grant holders, has recently become the group leader of his own research team at the Luxembourg Institute of Health! Find out more about Angel’s research and his new lab: bit.ly/3DZW6UN
Future Leader Spotlight: Dr Ángel Álvarez-Prado
One of our Future Leaders, Dr Ángel Álvarez-Prado, is now leading his own research group at the Luxembourg Institute of Health. Read more.
bit.ly
March 18, 2025 at 11:53 AM
This wouldn’t have been possible without the support of the @braintumourcharity.bsky.social, they’re doing a fantastic job helping not only us scientists, but also patients and families ❤️
Thank you! 🙏
Thank you! 🙏
It is disappointing that we still need to fight against social exclusion and discrimination, it is discouraging to witness abusive governments attempt to shut down critical thinking, but we will stand together for human dignity, freedom and knowledge as a vehicle to protect these. Please sign ⬇️
Now, more than ever, the #global #science community needs to stand together - #united against those who attack science 🧪, who seek to diminish #scientists, who destroy critical programs that advance #equality, #diversity and #inclusion
Please consider to join us in signing the #MilanDeclaration ⏬
Please consider to join us in signing the #MilanDeclaration ⏬
March 5, 2025 at 1:14 PM
It is disappointing that we still need to fight against social exclusion and discrimination, it is discouraging to witness abusive governments attempt to shut down critical thinking, but we will stand together for human dignity, freedom and knowledge as a vehicle to protect these. Please sign ⬇️
Reposted by Ángel Álvarez-Prado
Excited to share a new paper from our lab 😀
We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪
So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠?
Massara et al 2025
www.cell.com/iscience/ful...
We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪
So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠?
Massara et al 2025
www.cell.com/iscience/ful...
February 10, 2025 at 2:03 PM
Excited to share a new paper from our lab 😀
We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪
So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠?
Massara et al 2025
www.cell.com/iscience/ful...
We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪
So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠?
Massara et al 2025
www.cell.com/iscience/ful...
Reposted by Ángel Álvarez-Prado
Professor @charlesswanton.bsky.social will be opening the #EACR2025 Annual Congress with his Keynote Talk: 'Myeloid Mayhem: Inflammation driven lung cancer initiation and progression'
Explore the impressive scientific programme: 2025.eacr.org/programme
Explore the impressive scientific programme: 2025.eacr.org/programme
February 7, 2025 at 1:58 PM
Professor @charlesswanton.bsky.social will be opening the #EACR2025 Annual Congress with his Keynote Talk: 'Myeloid Mayhem: Inflammation driven lung cancer initiation and progression'
Explore the impressive scientific programme: 2025.eacr.org/programme
Explore the impressive scientific programme: 2025.eacr.org/programme
Reposted by Ángel Álvarez-Prado
Today is #WorldCancerDay
Did you know❓
Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life.
Learn more 👉bit.ly/2NeFF8B
Did you know❓
Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life.
Learn more 👉bit.ly/2NeFF8B
February 4, 2025 at 9:11 AM
Today is #WorldCancerDay
Did you know❓
Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life.
Learn more 👉bit.ly/2NeFF8B
Did you know❓
Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life.
Learn more 👉bit.ly/2NeFF8B