Jain_Akanksha_
@akanksha-jain.bsky.social
Neural MorphoGenomics Lab @DMLS, Uni Zurich. •4D tissue morphogenesis• Human organoids •Developmental biology. Biologist by training, historian by heart. Previous @ETH @mpicbg @DBS-TIFR
https://akankshajain2022.github.io/AkankshaJain.github.io/
https://akankshajain2022.github.io/AkankshaJain.github.io/
Reposted by Jain_Akanksha_
NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
November 11, 2025 at 6:10 PM
NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
October 7, 2025 at 11:57 AM
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
Reposted by Jain_Akanksha_
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.
I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
October 4, 2025 at 5:47 AM
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.
I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
Reposted by Jain_Akanksha_
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
September 26, 2025 at 12:55 PM
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
Reposted by Jain_Akanksha_
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...
Cell-extrinsic controls over neocortical neuron fate and diversity
Cell-extrinsic cues are key for neocortical cell identity and diversity.
www.science.org
September 19, 2025 at 6:04 AM
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...
Reposted by Jain_Akanksha_
This is absolutely a must read. We are in deep trouble and I am even less optimistic than the authors.
AI can now generate fake microscopy images that are nearly impossible to detect. A serious threat to scientific integrity—and we’re not prepared for it.
Commentary in @natnano.nature.com
#nanotechnology
Commentary in @natnano.nature.com
#nanotechnology
September 15, 2025 at 11:10 AM
This is absolutely a must read. We are in deep trouble and I am even less optimistic than the authors.
Reposted by Jain_Akanksha_
Another #preprint: "Elasticity and plasticity of epithelial gap closure", from the #PhD work of Maryam Setoudeh:
arxiv.org/abs/2509.05110
This one required a lot of (I think) beautiful #mechanics!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
arxiv.org/abs/2509.05110
This one required a lot of (I think) beautiful #mechanics!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
September 8, 2025 at 7:51 AM
Another #preprint: "Elasticity and plasticity of epithelial gap closure", from the #PhD work of Maryam Setoudeh:
arxiv.org/abs/2509.05110
This one required a lot of (I think) beautiful #mechanics!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
arxiv.org/abs/2509.05110
This one required a lot of (I think) beautiful #mechanics!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
Reposted by Jain_Akanksha_
Our work is motivated by Tribolium serosa closure, a particularly simple instance of epithelial gap closure:
nature.com/articles/s41467-020-19356-x
@akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
nature.com/articles/s41467-020-19356-x
@akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
Regionalized tissue fluidization is required for epithelial gap closure during insect gastrulation - Nature Communications
The mechanics of embryonic tissue spreading over spherical eggs is not fully understood. Here, the authors show that during gastrulation in the red flour beetle, extraembryonic tissue epiboly is facil...
nature.com
September 8, 2025 at 7:51 AM
Our work is motivated by Tribolium serosa closure, a particularly simple instance of epithelial gap closure:
nature.com/articles/s41467-020-19356-x
@akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
nature.com/articles/s41467-020-19356-x
@akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
Reposted by Jain_Akanksha_
Join us on November 4th!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
September 8, 2025 at 11:09 AM
Join us on November 4th!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
Reposted by Jain_Akanksha_
Super excited that our group will be supported by an ERC Starting Grant!
In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.
We'll have PhD and Postdoc positions available, please get in touch if interested!
In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.
We'll have PhD and Postdoc positions available, please get in touch if interested!
Why do some cells become neurons and others muscle?
Physicist Prof. David Brückner @davidbrueckner.bsky.social @biozentrum.unibas.ch @unibas.ch receives a prestigious #ERCStartingGrant to uncover how cells make life-shaping decisions. @erc.europa.eu
www.biozentrum.unibas.ch/news/detail/...
Physicist Prof. David Brückner @davidbrueckner.bsky.social @biozentrum.unibas.ch @unibas.ch receives a prestigious #ERCStartingGrant to uncover how cells make life-shaping decisions. @erc.europa.eu
www.biozentrum.unibas.ch/news/detail/...
ERC Starting Grant for Physicist David Brückner
How do cells decide which role to take on in the body? Prof. David Brückner from the Biozentrum of the University of Basel is investigating this and similar questions. Over the next five years, a Star...
www.biozentrum.unibas.ch
September 4, 2025 at 11:27 AM
Super excited that our group will be supported by an ERC Starting Grant!
In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.
We'll have PhD and Postdoc positions available, please get in touch if interested!
In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.
We'll have PhD and Postdoc positions available, please get in touch if interested!
Reposted by Jain_Akanksha_
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Jain_Akanksha_
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
Mechanical forces drive evolutionary change
A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.
www.mpi-cbg.de
September 3, 2025 at 3:26 PM
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
September 3, 2025 at 10:43 PM
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
Reposted by Jain_Akanksha_
Once is an exception, twice is a trend, thrice is a tradition!
Save the date for our now-traditional annual OME-NGFF extravaganza in Zurich!
Whether you’ve just heard about OME-NGFF and are curious to learn more or if you are working with it every day, there is something for everyone this year!
Save the date for our now-traditional annual OME-NGFF extravaganza in Zurich!
Whether you’ve just heard about OME-NGFF and are curious to learn more or if you are working with it every day, there is something for everyone this year!
We're happy to announce the 2025 International OME-NGFF workshop 🎉
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
August 25, 2025 at 1:50 PM
Once is an exception, twice is a trend, thrice is a tradition!
Save the date for our now-traditional annual OME-NGFF extravaganza in Zurich!
Whether you’ve just heard about OME-NGFF and are curious to learn more or if you are working with it every day, there is something for everyone this year!
Save the date for our now-traditional annual OME-NGFF extravaganza in Zurich!
Whether you’ve just heard about OME-NGFF and are curious to learn more or if you are working with it every day, there is something for everyone this year!
Reposted by Jain_Akanksha_
We're happy to announce the 2025 International OME-NGFF workshop 🎉
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
August 25, 2025 at 9:07 AM
We're happy to announce the 2025 International OME-NGFF workshop 🎉
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
Reposted by Jain_Akanksha_
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 25, 2025 at 9:06 AM
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A continued highlight of the year for me, right from the first @embo.org #LISH. Always a fantastic course, impressive student projects, advanced lightsheet imaging for various samples AND data analysis in two weeks. Plus I get to visit my beloved Dresden, with CBG and #LISH veterans. Bis bald!
August 23, 2025 at 7:08 PM
Reposted by Jain_Akanksha_
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Jain_Akanksha_
Honored to receive the @isrbio.bsky.social Rising Star Award for our work in regeneration biology! Grateful to the committee and our colleagues for the recognition. A huge motivation for the lab. Excited to give the award talk in Madison next week and connect with everyone! 😎🥳🍾 shorturl.at/LnkSt
2025 Award Winners
www.isrbio.org
August 7, 2025 at 3:27 PM
Honored to receive the @isrbio.bsky.social Rising Star Award for our work in regeneration biology! Grateful to the committee and our colleagues for the recognition. A huge motivation for the lab. Excited to give the award talk in Madison next week and connect with everyone! 😎🥳🍾 shorturl.at/LnkSt
Reposted by Jain_Akanksha_
Day three of #LISH25 beginning with a bang by @akanksha-jain.bsky.social talking about lightsheet-powered understanding of Morphogenesis of #insects (done with me @mpi-cbg.de) and brain #organoids which is also the future of Akanksha’s newly minted independent lab.
August 13, 2025 at 7:10 AM
Day three of #LISH25 beginning with a bang by @akanksha-jain.bsky.social talking about lightsheet-powered understanding of Morphogenesis of #insects (done with me @mpi-cbg.de) and brain #organoids which is also the future of Akanksha’s newly minted independent lab.
Nostalgia and Deja vu! Listening to @maweigert.bsky.social back at the incredible @mpi-cbg.de for @embo.org #LISH2025. Here after six years, the gray auditorium reminds of my thoughts when I sat here for my PhD selection interviews that included him!
August 12, 2025 at 8:57 AM
Nostalgia and Deja vu! Listening to @maweigert.bsky.social back at the incredible @mpi-cbg.de for @embo.org #LISH2025. Here after six years, the gray auditorium reminds of my thoughts when I sat here for my PhD selection interviews that included him!
Reposted by Jain_Akanksha_
We are today kicking off the two-week @embo.org practical course on #Lightsheet # Microscopy at @mpi-cbg.de in #Dresden. This is the fifth iteration of the course. Hashtag #LISH2025
meetings.embo.org/event/25-lsm
meetings.embo.org/event/25-lsm
Light sheet microscopy
Light sheet microscopy is a technology that enables near-isotropic imaging of large biological specimens over time. It opens new avenues to study biological processes with unprecedented imaging speed…
meetings.embo.org
August 11, 2025 at 7:49 AM
We are today kicking off the two-week @embo.org practical course on #Lightsheet # Microscopy at @mpi-cbg.de in #Dresden. This is the fifth iteration of the course. Hashtag #LISH2025
meetings.embo.org/event/25-lsm
meetings.embo.org/event/25-lsm
Reposted by Jain_Akanksha_
Looks like private funders, HHMI,CZI etc., are not going to “save” US research. Europe is setting up mechanisms to attract US researchers & it may work. But, common, target junior talent, don’t shower money on superstars who will be flying professors & return to US when the science winter passes.
August 10, 2025 at 3:35 PM
Looks like private funders, HHMI,CZI etc., are not going to “save” US research. Europe is setting up mechanisms to attract US researchers & it may work. But, common, target junior talent, don’t shower money on superstars who will be flying professors & return to US when the science winter passes.
Reposted by Jain_Akanksha_
🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
August 9, 2025 at 8:03 AM
🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
Reposted by Jain_Akanksha_
Out now! Our very first paper@crick.ac.uk, an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️
www.cell.com/developmenta...
www.cell.com/developmenta...
August 6, 2025 at 4:36 PM
Out now! Our very first paper@crick.ac.uk, an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️
www.cell.com/developmenta...
www.cell.com/developmenta...