Aidan Lakshman
@ahl27.bsky.social
PhD Candidate in Bioinformatics at University of Pittsburgh
I build methods for large scale comparative phylogenetics
www.AHL27.com
I build methods for large scale comparative phylogenetics
www.AHL27.com
EvoWeaver has been chosen as one of the "50 best recently published papers" in the "Computational and Theoretical Biology" collection at Nature Communications!
Check out the full collection here: www.nature.com/collections/...
Original paper: www.nature.com/articles/s41...
#bioinformatics #rstats
Check out the full collection here: www.nature.com/collections/...
Original paper: www.nature.com/articles/s41...
#bioinformatics #rstats
Computational and Theoretical Biology
As we navigate the era of big data in biological research, advanced computational techniques, such as mathematical models and machine learning algorithms, are ...
www.nature.com
May 13, 2025 at 4:14 PM
EvoWeaver has been chosen as one of the "50 best recently published papers" in the "Computational and Theoretical Biology" collection at Nature Communications!
Check out the full collection here: www.nature.com/collections/...
Original paper: www.nature.com/articles/s41...
#bioinformatics #rstats
Check out the full collection here: www.nature.com/collections/...
Original paper: www.nature.com/articles/s41...
#bioinformatics #rstats
Reposted by Aidan Lakshman
Genome annotation is one of the things that we really need AI / machine learning to crack. New software makes it a little easier, but this one is a really interesting take on the problem.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
www.nature.com
April 29, 2025 at 4:42 AM
Genome annotation is one of the things that we really need AI / machine learning to crack. New software makes it a little easier, but this one is a really interesting take on the problem.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Aidan Lakshman
Proud to announce a new publication from the lab: EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals
www.nature.com/articles/s41...
www.nature.com/articles/s41...
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
www.nature.com
April 28, 2025 at 1:47 PM
Proud to announce a new publication from the lab: EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Aidan Lakshman
It's my absolute pleasure to say that we have a new paper from the lab out. This work uses evolutionary lineages to discover functional associations in proteins. We call it EvoWeaver.
wrightlabscience.com/publications
wrightlabscience.com/publications
Publications
scientific publications, bioinformatics, genomes, research, antibiotics, antibiotic resistance, genomics, evolution
wrightlabscience.com
April 24, 2025 at 4:38 PM
It's my absolute pleasure to say that we have a new paper from the lab out. This work uses evolutionary lineages to discover functional associations in proteins. We call it EvoWeaver.
wrightlabscience.com/publications
wrightlabscience.com/publications
Reposted by Aidan Lakshman
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals
->Nature | More info from EcoSearch
->Nature | More info from EcoSearch
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals
EvoWeaver is available as part of the SynExtend (v1.19.0) package74 for R75, which is distributed via the Bioconductor76 platform. A comprehensive description of input/output and examples of running each algorithm are contained in the supplementary R Markdown file available on...
www.nature.com
April 24, 2025 at 9:02 PM
Reposted by Aidan Lakshman
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41... 🧬🖥️🧪 #Rstats bioconductor.org/packages/Syn...
April 25, 2025 at 8:00 PM
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41... 🧬🖥️🧪 #Rstats bioconductor.org/packages/Syn...
Reposted by Aidan Lakshman
EvoWeaver identifies genes working together using evolutionary information and infers protein functions using only genomic sequences. @ahl27.bsky.social @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
www.nature.com
April 24, 2025 at 5:18 PM
EvoWeaver identifies genes working together using evolutionary information and infers protein functions using only genomic sequences. @ahl27.bsky.social @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Wrapping up a project on #clustering #networks in #R (and #C) — I wrote a 4-part #blogpost on the stuff I learned. >1M nodes and >75M edges now runs with 500MB RAM in under 5min & billions of nodes are doable in under a day. Part 1 of the series is here: www.ahl27.com/posts/2024/1...
Efficient File I/O, Part 1: Some (somewhat) surprising findings on C’s fseek
I’m working a lot with files for my latest research project, ExoLabel. I’ve (mostly) finished ensuring that the algorithm itself is accurate, so lately I’ve been turning my attention to optimizing its...
www.ahl27.com
December 18, 2024 at 3:43 PM
Wrapping up a project on #clustering #networks in #R (and #C) — I wrote a 4-part #blogpost on the stuff I learned. >1M nodes and >75M edges now runs with 500MB RAM in under 5min & billions of nodes are doable in under a day. Part 1 of the series is here: www.ahl27.com/posts/2024/1...