Adrien Leger
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adrienleger.bsky.social
Adrien Leger
@adrienleger.bsky.social
Director of Modified Bases Research at @nanoporetech.com
EMBL-EBI alumni, keen cyclist and father of two.
Views are my own. Reposts are not endorsement.
🚨 We’re hiring ! 🚨
Join our cutting-edge research team as a molecular biologist at @nanoporetech.com HQ in Oxford.
Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI

👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...
June 2, 2025 at 9:54 AM
For comparison here is what you would see with standard released models which can "only" detect m6A, m5C, PseudoU and Inosine for the same areas with @nanoporetech.com dRNA seq.
What you're missing clearly matters here #WYMM
November 28, 2024 at 12:12 PM
We have been busing working on models to detect all 2'Ome-RNA modified nucleotides on top of PseudoU, m6A, m5C and Inosine using @nanoporetech.com direct RNA sequencing.
This is still very preliminary but here are a few examples of what it looks like on Human #rRNA prepared with standard lib prep 🤩
November 28, 2024 at 12:12 PM