Zhaolong Adrian Li
@adrianzhaolong.bsky.social
#WashU MD-PhD student. Focuses: MRI, psychiatry, obesity, child development, SDOH, Wolfram syndrome. Pubs: https://scholar.google.com/citations?hl=en&user=qPRwyN0AAAAJ
Reposted by Zhaolong Adrian Li
Restricted normalized isotropic values were associated with age and bidirectional links to weight gain. ja.ma/4lLyILB
July 23, 2025 at 3:20 PM
Restricted normalized isotropic values were associated with age and bidirectional links to weight gain. ja.ma/4lLyILB
Reposted by Zhaolong Adrian Li
FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...
Data Sharing - ABCD Study
abcdstudy.org
March 31, 2025 at 5:53 PM
FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...
Reposted by Zhaolong Adrian Li
New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety
Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eatin...
www.science.org
March 27, 2025 at 6:17 PM
New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Reposted by Zhaolong Adrian Li
New blog post in the making. I guess some topics (unfortunately?) never get old.
March 19, 2025 at 10:05 AM
New blog post in the making. I guess some topics (unfortunately?) never get old.
Reposted by Zhaolong Adrian Li
Are you doing EMA research and wonder how to go about it? In recent work we've adressed some open questions and challenges, here is a brief summary of papers and materials.
🧵 #PsychSciSky 🧪 #StatsSky
🧵 #PsychSciSky 🧪 #StatsSky
March 12, 2025 at 9:58 AM
Are you doing EMA research and wonder how to go about it? In recent work we've adressed some open questions and challenges, here is a brief summary of papers and materials.
🧵 #PsychSciSky 🧪 #StatsSky
🧵 #PsychSciSky 🧪 #StatsSky
Reposted by Zhaolong Adrian Li
If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...
Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits
The rapid development and clinical use of brain stimulation has renewed debates about whether to define and accredit a pathway for clinical subspecial…
www.sciencedirect.com
March 7, 2025 at 12:45 PM
If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...
Reposted by Zhaolong Adrian Li
New paper in Imaging Neuroscience by Maria Hakonen, Jyrki Ahveninen, et al:
Individual connectivity-based parcellations reflect functional properties of human auditory cortex
doi.org/10.1162/imag...
Individual connectivity-based parcellations reflect functional properties of human auditory cortex
doi.org/10.1162/imag...
March 3, 2025 at 5:45 PM
New paper in Imaging Neuroscience by Maria Hakonen, Jyrki Ahveninen, et al:
Individual connectivity-based parcellations reflect functional properties of human auditory cortex
doi.org/10.1162/imag...
Individual connectivity-based parcellations reflect functional properties of human auditory cortex
doi.org/10.1162/imag...
Reposted by Zhaolong Adrian Li
We are thrilled that Holmes lab recent paper by Xihan Zhang et al. has been featured on the cover of The Transmitter!@thetransmitter.bsky.social!
Check out the paper here: tinyurl.com/cellnetworks
And the article 🖇️ 🧬
www.thetransmitter.org/neuroanatomy...
Check out the paper here: tinyurl.com/cellnetworks
And the article 🖇️ 🧬
www.thetransmitter.org/neuroanatomy...
Cell ‘fingerprints’ identify distinct cortical networks
These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a new study.
www.thetransmitter.org
March 3, 2025 at 6:28 PM
We are thrilled that Holmes lab recent paper by Xihan Zhang et al. has been featured on the cover of The Transmitter!@thetransmitter.bsky.social!
Check out the paper here: tinyurl.com/cellnetworks
And the article 🖇️ 🧬
www.thetransmitter.org/neuroanatomy...
Check out the paper here: tinyurl.com/cellnetworks
And the article 🖇️ 🧬
www.thetransmitter.org/neuroanatomy...
Reposted by Zhaolong Adrian Li
Last week to grab a virtual registration for Whistler Brain starting this weekend - get the link for the talks!
web.cvent.com/event/34b0c2...
web.cvent.com/event/34b0c2...
February 18, 2025 at 2:00 AM
Last week to grab a virtual registration for Whistler Brain starting this weekend - get the link for the talks!
web.cvent.com/event/34b0c2...
web.cvent.com/event/34b0c2...
Reposted by Zhaolong Adrian Li
As if there wasn’t enough to worry about…
It turns out the Salience (SAL) and Parietal Memory Networks (PMN) are the same thing!
😩😩😩
🧵
It turns out the Salience (SAL) and Parietal Memory Networks (PMN) are the same thing!
😩😩😩
🧵
February 1, 2025 at 12:00 AM
As if there wasn’t enough to worry about…
It turns out the Salience (SAL) and Parietal Memory Networks (PMN) are the same thing!
😩😩😩
🧵
It turns out the Salience (SAL) and Parietal Memory Networks (PMN) are the same thing!
😩😩😩
🧵
Reposted by Zhaolong Adrian Li
New blog up: solomonkurz.netlify.app/blog/2025-02...
This time I dip my toes into causal inference for quasi-experiments using matching methods, and my use case has missing data complications. Many thanks to @dingdingpeng.the100.ci and
@noahgreifer.bsky.social
for their peer review! #RStats
This time I dip my toes into causal inference for quasi-experiments using matching methods, and my use case has missing data complications. Many thanks to @dingdingpeng.the100.ci and
@noahgreifer.bsky.social
for their peer review! #RStats
Matching, missing data, a quasi-experiment, and causal inference--Oh my! | A. Solomon Kurz
I'm finally dipping my does into causal inference for quasi-experiments, and my first use case has missing data. In this post we practice propensity score matching with multiply-imputed data sets, and...
solomonkurz.netlify.app
February 4, 2025 at 4:36 PM
New blog up: solomonkurz.netlify.app/blog/2025-02...
This time I dip my toes into causal inference for quasi-experiments using matching methods, and my use case has missing data complications. Many thanks to @dingdingpeng.the100.ci and
@noahgreifer.bsky.social
for their peer review! #RStats
This time I dip my toes into causal inference for quasi-experiments using matching methods, and my use case has missing data complications. Many thanks to @dingdingpeng.the100.ci and
@noahgreifer.bsky.social
for their peer review! #RStats
Reposted by Zhaolong Adrian Li
It feels weird to be promoting myself in the midst of *gestures wildly*, but I've been working on this project for a while and I'm super proud of it! One possible answer to the question of "What to do about the low reliability of task fMRI?" a 🧵 #neuroskyence #fMRI #Neuroimaging (1/11):
Enhancing task fMRI individual difference research with neural signatures https://www.medrxiv.org/content/10.1101/2025.01.30.25321355v1
February 1, 2025 at 8:04 PM
It feels weird to be promoting myself in the midst of *gestures wildly*, but I've been working on this project for a while and I'm super proud of it! One possible answer to the question of "What to do about the low reliability of task fMRI?" a 🧵 #neuroskyence #fMRI #Neuroimaging (1/11):
Reposted by Zhaolong Adrian Li
𝗜𝗻𝘀𝘂𝗹𝗮 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝗶𝗻𝘃𝗼𝗹𝘃𝗲𝗱 𝗶𝗻 𝗶𝗺𝗺𝘂𝗻𝗲 𝗵𝗼𝗺𝗲𝗼𝘀𝘁𝗮𝘀𝗶𝘀
The insula is the place of magic in the brain... (one of them at least)
www.nature.com/articles/s41...
(h/t @jrbneuropsiq.bsky.social )
#neuroskyence
The insula is the place of magic in the brain... (one of them at least)
www.nature.com/articles/s41...
(h/t @jrbneuropsiq.bsky.social )
#neuroskyence
January 29, 2025 at 9:20 PM
𝗜𝗻𝘀𝘂𝗹𝗮 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝗶𝗻𝘃𝗼𝗹𝘃𝗲𝗱 𝗶𝗻 𝗶𝗺𝗺𝘂𝗻𝗲 𝗵𝗼𝗺𝗲𝗼𝘀𝘁𝗮𝘀𝗶𝘀
The insula is the place of magic in the brain... (one of them at least)
www.nature.com/articles/s41...
(h/t @jrbneuropsiq.bsky.social )
#neuroskyence
The insula is the place of magic in the brain... (one of them at least)
www.nature.com/articles/s41...
(h/t @jrbneuropsiq.bsky.social )
#neuroskyence
Reposted by Zhaolong Adrian Li
The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon
@ndosenbach.bsky.social @gordonneuro.bsky.social
www.nature.com/articles/s41...
@ndosenbach.bsky.social @gordonneuro.bsky.social
www.nature.com/articles/s41...
The brain’s action-mode network - Nature Reviews Neuroscience
The brain enters an action-mode of function during goal-directed behaviour. In this Perspective, Dosenbach, Raiche and Gordon describe “action-mode” as an informative functional label that reduce...
www.nature.com
January 17, 2025 at 2:45 PM
The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon
@ndosenbach.bsky.social @gordonneuro.bsky.social
www.nature.com/articles/s41...
@ndosenbach.bsky.social @gordonneuro.bsky.social
www.nature.com/articles/s41...
Reposted by Zhaolong Adrian Li
Out in @natureneuro.bsky.social today 🥂
Cytoarchitecture, wiring and signal flow of the human default mode network
Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations
Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
Cytoarchitecture, wiring and signal flow of the human default mode network
Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations
Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow - Nature Neuroscience
The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to input from the sensory cortex and a core relatively insulated from environmental input, and it uniquely balances its output across sensory hierarchies.
www.nature.com
January 28, 2025 at 2:24 PM
Out in @natureneuro.bsky.social today 🥂
Cytoarchitecture, wiring and signal flow of the human default mode network
Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations
Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
Cytoarchitecture, wiring and signal flow of the human default mode network
Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations
Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏
Reposted by Zhaolong Adrian Li
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
January 24, 2025 at 12:02 AM
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
Reposted by Zhaolong Adrian Li
In our 🚨 NEW PAPER 🚨 "Beyond the income-achievement gap: The role of individual, family, and environmental factors in cognitive resilience among low-income youth", we used machine learning to characterise predictors of cognitive resilience.
acamh.onlinelibrary.wiley.com/doi/full/10....
acamh.onlinelibrary.wiley.com/doi/full/10....
JCPP Advances | ACAMH Child Development Journal | Wiley Online Library
Machine learning based prediction of cognitive resilience among low income youth.
acamh.onlinelibrary.wiley.com
January 24, 2025 at 3:46 PM
In our 🚨 NEW PAPER 🚨 "Beyond the income-achievement gap: The role of individual, family, and environmental factors in cognitive resilience among low-income youth", we used machine learning to characterise predictors of cognitive resilience.
acamh.onlinelibrary.wiley.com/doi/full/10....
acamh.onlinelibrary.wiley.com/doi/full/10....
Reposted by Zhaolong Adrian Li
Longitudinal Trajectories of Cognition and Neural Metrics as Predictors of Persistent Distressing Psychotic-Like Experiences Across Middle Childhood and Early Adolescence | bioRxiv www.biorxiv.org/content/10.1...
January 23, 2025 at 1:30 AM
Longitudinal Trajectories of Cognition and Neural Metrics as Predictors of Persistent Distressing Psychotic-Like Experiences Across Middle Childhood and Early Adolescence | bioRxiv www.biorxiv.org/content/10.1...
Reposted by Zhaolong Adrian Li
Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠
New paper in Imaging Neuroscience by Julia Moser, Damien A. Fair, et al:
Multi-echo acquisition and thermal denoising advances precision functional imaging
direct.mit.edu/imag/article...
Multi-echo acquisition and thermal denoising advances precision functional imaging
direct.mit.edu/imag/article...
January 10, 2025 at 5:11 PM
Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠
Reposted by Zhaolong Adrian Li
Another fascinating study from the Yasuda lab:
www.nature.com/articles/s41...
CaMKII inhibition immediately after training impairs memory transiently. Memory recovers a day later!
www.nature.com/articles/s41...
CaMKII inhibition immediately after training impairs memory transiently. Memory recovers a day later!
Formation of long-term memory without short-term memory revealed by CaMKII inhibition - Nature Neuroscience
Inhibiting CaMKII impairs short-term memory (STM) in mice during an avoidance task but does not affect long-term memory (LTM). This suggests that STM and LTM are processed differently, with CaMKII cri...
www.nature.com
December 6, 2024 at 9:33 PM
Another fascinating study from the Yasuda lab:
www.nature.com/articles/s41...
CaMKII inhibition immediately after training impairs memory transiently. Memory recovers a day later!
www.nature.com/articles/s41...
CaMKII inhibition immediately after training impairs memory transiently. Memory recovers a day later!
Reposted by Zhaolong Adrian Li
We often mind-wander about our past, present, & future. What happens when our minds drift towards our bodies? In a new fMRI study (n ~ 500), @leahbanellis.bsky.social + team discovers unique neural, affective, & physiological correlates of "body-wandering" at rest. www.biorxiv.org/content/10.1...
December 10, 2024 at 8:05 AM
We often mind-wander about our past, present, & future. What happens when our minds drift towards our bodies? In a new fMRI study (n ~ 500), @leahbanellis.bsky.social + team discovers unique neural, affective, & physiological correlates of "body-wandering" at rest. www.biorxiv.org/content/10.1...
Reposted by Zhaolong Adrian Li
Took me two solid days of data munging and coding but I finally figured out how to create these gorgeous connectome/circle plot diagrams. This is the Yeo 7-network brain parcellation, with major connections in a group of healthy adults.
December 5, 2024 at 8:11 AM
Took me two solid days of data munging and coding but I finally figured out how to create these gorgeous connectome/circle plot diagrams. This is the Yeo 7-network brain parcellation, with major connections in a group of healthy adults.
Reposted by Zhaolong Adrian Li
Another fun, low coding threshold, resource: partR2 package is useful for being able to flexibly pull R2 under various specifications (e.g., marginal, conditional, partial, inclusive, etc.) in generalized linear mixed models.
#Rstats #Statistics #AcademicSky
cran.r-project.org/web/packages...
#Rstats #Statistics #AcademicSky
cran.r-project.org/web/packages...
November 26, 2024 at 9:28 PM
Another fun, low coding threshold, resource: partR2 package is useful for being able to flexibly pull R2 under various specifications (e.g., marginal, conditional, partial, inclusive, etc.) in generalized linear mixed models.
#Rstats #Statistics #AcademicSky
cran.r-project.org/web/packages...
#Rstats #Statistics #AcademicSky
cran.r-project.org/web/packages...