Emanuel Tenorio
@97emax.bsky.social
PhD Student @ Penninger Lab 🧪
Reposted by Emanuel Tenorio
Perfect for our first post: big collaborate effort spearheaded by Masahiro Onji showing how sex hormones and RANK regulate gut expansion during reproduction 🤰🤱
Excited to share my latest paper, published today at @natureportfolio.bsky.social ! A big thank you to all our collaborators.
The paper shows how RANK drives intestinal epithelial expansion during reproduction.
#intestine #stemcells #pregnancy
www.nature.com/articles/s41...
The paper shows how RANK drives intestinal epithelial expansion during reproduction.
#intestine #stemcells #pregnancy
www.nature.com/articles/s41...
RANK drives structured intestinal epithelial expansion during pregnancy - Nature
The RANK–RANKL pathway drives intestinal epithelial expansion in pregnancy and lactation.
www.nature.com
December 6, 2024 at 8:36 AM
Perfect for our first post: big collaborate effort spearheaded by Masahiro Onji showing how sex hormones and RANK regulate gut expansion during reproduction 🤰🤱
Reposted by Emanuel Tenorio
Very nice coculture system from @lionellb.bsky.social 's lab! T cells form Crohn's Disease patients induce cell death when cocultured with autologous #organoids even after days of organoid subculture, imparing stem cell proliferation and affecting differentiation. #Gastrosky #immunology 🧪
Very proud of this one. Sarah Hamoudi, PhD student in the lab, developed autologous cocultures between mucosal T cells and epithelial organoids from control or from patients with Crohn's disease.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
T cell mediated impairment of epithelial integrity in Crohn's disease
T lymphocytes play a major role in intestinal homeostasis, with a particular impact on the balance between self-renewal and differentiation of intestinal epithelial cells (IECs). In Crohn's disease (C...
www.biorxiv.org
November 21, 2024 at 8:51 AM
Very nice coculture system from @lionellb.bsky.social 's lab! T cells form Crohn's Disease patients induce cell death when cocultured with autologous #organoids even after days of organoid subculture, imparing stem cell proliferation and affecting differentiation. #Gastrosky #immunology 🧪
🧪
Out today in Nature: "The Human Cell Atlas"! In my News and Views, I compare the cell atlas to early naturalists creating an atlas of South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
November 20, 2024 at 6:21 PM
🧪
🧪
An ambitious plan to map all 37 trillion cells in the human body is transforming understanding of how our bodies work.
The Human Cell Atlas reveals there are thousands of cell types, with some culprits in diseases such as inflammatory bowel disease & cystic fibrosis. 🧪
www.bbc.co.uk/news/article...
The Human Cell Atlas reveals there are thousands of cell types, with some culprits in diseases such as inflammatory bowel disease & cystic fibrosis. 🧪
www.bbc.co.uk/news/article...
Human Cell Atlas project transforms understanding of human body
Scientists are mapping out the 37 trillion cells of the human body and changing what we thought we knew
www.bbc.co.uk
November 20, 2024 at 6:08 PM
🧪
🧪
👋🏻Our November issue's out!
Cover: Imaging #Ovulation
👉🏼Comments on #embryo models & #MembraneContactSites
🔬on: #PlasmaMembrane #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more!
www.nature.com/ncb/volumes/...
Cover: Imaging #Ovulation
👉🏼Comments on #embryo models & #MembraneContactSites
🔬on: #PlasmaMembrane #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more!
www.nature.com/ncb/volumes/...
November 20, 2024 at 6:05 PM
🧪
Reposted by Emanuel Tenorio
Happy to transition to this platform to discuss science and share our fascination.
The movie below shows a dendritic cell, highlighting the remarkable ability of immune cells to navigate their cell body and to organise their intracellular cargo (nucleus in cyan).
(Kroll et al, EMBO J 2023)
The movie below shows a dendritic cell, highlighting the remarkable ability of immune cells to navigate their cell body and to organise their intracellular cargo (nucleus in cyan).
(Kroll et al, EMBO J 2023)
November 12, 2024 at 7:27 AM
Happy to transition to this platform to discuss science and share our fascination.
The movie below shows a dendritic cell, highlighting the remarkable ability of immune cells to navigate their cell body and to organise their intracellular cargo (nucleus in cyan).
(Kroll et al, EMBO J 2023)
The movie below shows a dendritic cell, highlighting the remarkable ability of immune cells to navigate their cell body and to organise their intracellular cargo (nucleus in cyan).
(Kroll et al, EMBO J 2023)
Reposted by Emanuel Tenorio
Even though there are great #devbio and #biophysics starter packs, I felt #morphogenesis & #organogenesis was missing as a subfield :D
Far from complete or full. Tell me if you want to be added!
go.bsky.app/PB6s8PQ
Far from complete or full. Tell me if you want to be added!
go.bsky.app/PB6s8PQ
November 19, 2024 at 7:14 PM
Even though there are great #devbio and #biophysics starter packs, I felt #morphogenesis & #organogenesis was missing as a subfield :D
Far from complete or full. Tell me if you want to be added!
go.bsky.app/PB6s8PQ
Far from complete or full. Tell me if you want to be added!
go.bsky.app/PB6s8PQ
Reposted by Emanuel Tenorio
Proud to share our latest paper in Science Immunology
- how #mastcell -derived #BH4/#serotonin drives postoperative pain in mice, revealing a potential therapeutic target for surgical pain:
scim.ag/87H
- how #mastcell -derived #BH4/#serotonin drives postoperative pain in mice, revealing a potential therapeutic target for surgical pain:
scim.ag/87H
Mast cell–derived BH4 and serotonin are critical mediators of postoperative pain
Mast cells and their BH4-serotonin metabolic axis are critical drivers of postoperative pain hypersensitivity in mice.
scim.ag
August 23, 2024 at 7:23 PM
Proud to share our latest paper in Science Immunology
- how #mastcell -derived #BH4/#serotonin drives postoperative pain in mice, revealing a potential therapeutic target for surgical pain:
scim.ag/87H
- how #mastcell -derived #BH4/#serotonin drives postoperative pain in mice, revealing a potential therapeutic target for surgical pain:
scim.ag/87H