TenaciousG
@1g223.bsky.social
Reposted by TenaciousG
In @science.org today my essay on predicting and preventing Alzheimer's disease (open-access)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Predicting and preventing Alzheimer’s disease
With all the advances in both the science of aging and artificial intelligence (AI), we are in a propitious position to accurately and precisely determine who is at high risk of developing Alzheimer’s...
www.science.org
May 29, 2025 at 6:00 PM
In @science.org today my essay on predicting and preventing Alzheimer's disease (open-access)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by TenaciousG
Please, take some time to listen to Teddy then share this.
Uniter
9-year old Teddy
“Recently…RFK Jr. made false comments about autism, like people with autism are broken, that autism caused by vaccines, and that people with autism will never have jobs or families. But that’s not true!
“I have autism & I’m not broken.”
@nj.com, www.tiktok.com/t/ZTjSfAeVL/
9-year old Teddy
“Recently…RFK Jr. made false comments about autism, like people with autism are broken, that autism caused by vaccines, and that people with autism will never have jobs or families. But that’s not true!
“I have autism & I’m not broken.”
@nj.com, www.tiktok.com/t/ZTjSfAeVL/
May 3, 2025 at 1:33 AM
Please, take some time to listen to Teddy then share this.
Reposted by TenaciousG
The Worst Person You Know Just Made Some Great Points
April 29, 2025 at 9:00 PM
The Worst Person You Know Just Made Some Great Points
Reposted by TenaciousG
The surprising result for a GLP-1 pill (orforglipron) is the magnitude of weight loss in a Phase 3 trial of participants with Type 2 diabetes. For still unexplained reasons, people with diabetes lose much less weight on GLP-1 drugs than those with obesity, w/o diabetes.
April 20, 2025 at 3:58 PM
The surprising result for a GLP-1 pill (orforglipron) is the magnitude of weight loss in a Phase 3 trial of participants with Type 2 diabetes. For still unexplained reasons, people with diabetes lose much less weight on GLP-1 drugs than those with obesity, w/o diabetes.
Reposted by TenaciousG
I made the graph from investor.lilly.com/news-release...
Here is the TIME piece (long read) which doesn't include this key point time.com/7278429/weig...
Here is the TIME piece (long read) which doesn't include this key point time.com/7278429/weig...
April 20, 2025 at 4:04 PM
I made the graph from investor.lilly.com/news-release...
Here is the TIME piece (long read) which doesn't include this key point time.com/7278429/weig...
Here is the TIME piece (long read) which doesn't include this key point time.com/7278429/weig...
Reposted by TenaciousG
Our gut microbiome and its metabolites play a critical role for our glucose regulation, as does diet and exercise for improving it, through modulating the gut microbiome
@naturemedicine.bsky.social
www.nature.com/articles/s41...
@naturemedicine.bsky.social
www.nature.com/articles/s41...
Microbiome–metabolome dynamics associated with impaired glucose control and responses to lifestyle changes - Nature Medicine
A map of microbiome–metabolome dynamics in people with type 2 diabetes identifies over 500 blood metabolites associated with impaired glucose control, with approximately one-third linked to an altered...
www.nature.com
April 8, 2025 at 2:19 PM
Our gut microbiome and its metabolites play a critical role for our glucose regulation, as does diet and exercise for improving it, through modulating the gut microbiome
@naturemedicine.bsky.social
www.nature.com/articles/s41...
@naturemedicine.bsky.social
www.nature.com/articles/s41...
Report: Elon's cybertrucks are deadlier than infamous Ford Pintos www.motherjones.com/politics/202...
Report: Elon's cybertrucks are deadlier than infamous Ford Pintos
It's just the latest reason to be skeptical of the car's safety record.
www.motherjones.com
April 3, 2025 at 9:42 PM
Report: Elon's cybertrucks are deadlier than infamous Ford Pintos www.motherjones.com/politics/202...
Reposted by TenaciousG
“The Bureau employs some 2,000 people in the city of 29,000.”
The Red Rural Recession.
www.thedailybeast.com/maga-junkie-...
The Red Rural Recession.
www.thedailybeast.com/maga-junkie-...
‘MAGA Junkie’ Fired in DOGE Cuts Now Regrets Voting for Trump: ‘I Expected Better’
“I was a MAGA junkie, a MAGA junkie who thought her government job would be safe with Donald Trump in office,” says West Virginia woman fired from the Bureau of Fiscal Service.
www.thedailybeast.com
March 29, 2025 at 4:22 AM
“The Bureau employs some 2,000 people in the city of 29,000.”
The Red Rural Recession.
www.thedailybeast.com/maga-junkie-...
The Red Rural Recession.
www.thedailybeast.com/maga-junkie-...
Reposted by TenaciousG
Not getting much attention, but the Senate GOP is about to start voting - to make sure banks can charge higher overdraft fees. Seriously.
Good time to let your Senators know what you think of that.
Good time to let your Senators know what you think of that.
March 27, 2025 at 12:36 AM
Not getting much attention, but the Senate GOP is about to start voting - to make sure banks can charge higher overdraft fees. Seriously.
Good time to let your Senators know what you think of that.
Good time to let your Senators know what you think of that.
Reposted by TenaciousG
From an operational security perspective, this is the highest level of fuckup imaginable. These people cannot keep America safe.
The Trump Administration Accidentally Texted Me Its War Plans
U.S. national-security leaders included me in a group chat about upcoming military strikes in Yemen. I didn’t think it could be real. Then the bombs started falling.
www.theatlantic.com
March 24, 2025 at 8:13 PM
From an operational security perspective, this is the highest level of fuckup imaginable. These people cannot keep America safe.
Reposted by TenaciousG
Another way of saying this is that Trump’s claims are so extreme that even judges appointed by Republicans agree
As we show in a forthcoming JOP paper, this is an important signal to higher courts about the undelying merits of the claims
As we show in a forthcoming JOP paper, this is an important signal to higher courts about the undelying merits of the claims
1/🧵 Judges across ideological lines are ruling against Trump at strikingly similar rates (84% liberal, 86% centrist, 82% conservative). This isn't partisan opposition to Trump—it's the judiciary functioning as intended by cutting across partisan lines to uphold the Constitution.
March 18, 2025 at 9:51 PM
Another way of saying this is that Trump’s claims are so extreme that even judges appointed by Republicans agree
As we show in a forthcoming JOP paper, this is an important signal to higher courts about the undelying merits of the claims
As we show in a forthcoming JOP paper, this is an important signal to higher courts about the undelying merits of the claims
Reposted by TenaciousG
If you live in NC, call every Republican politician you know. Call every farmer you know and ask them to do the same
When money walks , voters talk. Make sure they know this effects everyone in their town and state
www.wunc.org/news/2025-03...
When money walks , voters talk. Make sure they know this effects everyone in their town and state
www.wunc.org/news/2025-03...
USDA cancels $11 million in federal funding for North Carolina food banks
The USDA has notified the North Carolina Department of Agriculture and Consumer Services that it would terminate the agreement for the Local Food Purchase Assistance Program, which is one of the progr...
www.wunc.org
March 15, 2025 at 6:26 PM
If you live in NC, call every Republican politician you know. Call every farmer you know and ask them to do the same
When money walks , voters talk. Make sure they know this effects everyone in their town and state
www.wunc.org/news/2025-03...
When money walks , voters talk. Make sure they know this effects everyone in their town and state
www.wunc.org/news/2025-03...
Reposted by TenaciousG
Multiple sclerosis requires Epstein-Barr virus infection as an underpinning, exhibits self-directed antibodies to EBNA1, the virus's nuclear antigen, representing molecular mimicry. This combines with/ genetic risk factors (Figure, compared w/healthy controls)
@pnas.org
www.pnas.org/doi/epub/10....
@pnas.org
www.pnas.org/doi/epub/10....
March 10, 2025 at 7:21 PM
Multiple sclerosis requires Epstein-Barr virus infection as an underpinning, exhibits self-directed antibodies to EBNA1, the virus's nuclear antigen, representing molecular mimicry. This combines with/ genetic risk factors (Figure, compared w/healthy controls)
@pnas.org
www.pnas.org/doi/epub/10....
@pnas.org
www.pnas.org/doi/epub/10....
Reposted by TenaciousG
"Funding from the NIH was contributed to 354 of 356 drugs (99.4%) approved from 2010 to 2019 totaling $187 billion" #BioMed
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.
jamanetwork.com
March 10, 2025 at 3:13 PM
"Funding from the NIH was contributed to 354 of 356 drugs (99.4%) approved from 2010 to 2019 totaling $187 billion" #BioMed
Churchill at the White House 1942
March 6, 2025 at 1:39 AM
Churchill at the White House 1942
Roald Dahl's heartbreaking letter about his daughter who died of complications from measles.
March 1, 2025 at 3:34 PM
Roald Dahl's heartbreaking letter about his daughter who died of complications from measles.
Reposted by TenaciousG
Reposted by TenaciousG
Generations of American patriots, from our revolution onward, have fought for the principles Zelenskyy is risking his life to defend. But today, Donald Trump and JD Vance attacked Zelenskyy and pressured him to surrender the freedom of his people to the KGB war criminal who invaded Ukraine.
ZELENSKYY: Putin broke the ceasefire. What kind of diplomacy, JD, are you speaking about?
VANCE: I think it's disrespectful to come into the Oval Office and try to litigate this in front of the American media
VANCE: I think it's disrespectful to come into the Oval Office and try to litigate this in front of the American media
February 28, 2025 at 6:38 PM
Generations of American patriots, from our revolution onward, have fought for the principles Zelenskyy is risking his life to defend. But today, Donald Trump and JD Vance attacked Zelenskyy and pressured him to surrender the freedom of his people to the KGB war criminal who invaded Ukraine.
Reposted by TenaciousG
Leadership is doubling down, but GOP members are getting nervous about the budget’s extreme unpopularity.
You can call your Representative now at 202-224-3121.
You can call your Representative now at 202-224-3121.
Looks like tomorrow will bring votes on a Republican plan to fund tax cuts for the rich by slashing Medicaid.
So this is a great time to contact your Member of Congress.
So this is a great time to contact your Member of Congress.
February 25, 2025 at 2:13 PM
Leadership is doubling down, but GOP members are getting nervous about the budget’s extreme unpopularity.
You can call your Representative now at 202-224-3121.
You can call your Representative now at 202-224-3121.
Reposted by TenaciousG
🚨If YOU live in 1 of these REPUBLICAN districts, these are the MOST vulnerable R's whose seats will be FLIPPED next year if they vote YES to cut Medicaid.
Please CALL your representative the vote is TOMORROW & help SAVE this program. YOUR voice does matter and does make a DIFFERENCE. 202-224-3121.🚨
Please CALL your representative the vote is TOMORROW & help SAVE this program. YOUR voice does matter and does make a DIFFERENCE. 202-224-3121.🚨
February 24, 2025 at 6:10 PM
🚨If YOU live in 1 of these REPUBLICAN districts, these are the MOST vulnerable R's whose seats will be FLIPPED next year if they vote YES to cut Medicaid.
Please CALL your representative the vote is TOMORROW & help SAVE this program. YOUR voice does matter and does make a DIFFERENCE. 202-224-3121.🚨
Please CALL your representative the vote is TOMORROW & help SAVE this program. YOUR voice does matter and does make a DIFFERENCE. 202-224-3121.🚨
Reposted by TenaciousG
Looks like tomorrow will bring votes on a Republican plan to fund tax cuts for the rich by slashing Medicaid.
So this is a great time to contact your Member of Congress.
So this is a great time to contact your Member of Congress.
February 25, 2025 at 12:54 AM
Looks like tomorrow will bring votes on a Republican plan to fund tax cuts for the rich by slashing Medicaid.
So this is a great time to contact your Member of Congress.
So this is a great time to contact your Member of Congress.
Native WNYer here. I called and left a VM thanking Gov Mills of Maine for speaking truth to power. Here is the number.
207-287-3531
207-287-3531
February 22, 2025 at 1:48 PM
Native WNYer here. I called and left a VM thanking Gov Mills of Maine for speaking truth to power. Here is the number.
207-287-3531
207-287-3531
Reposted by TenaciousG
I will use every tool at my disposal to protect this country from Trump. I will litigate to defend voting rights until there are no cases left to bring. I will speak out against authoritarianism until my last breath.
I will not back down. I will not bow or scrape. I will never obey.
I will not back down. I will not bow or scrape. I will never obey.
My Open Letter to Elon Musk
From Marc | Elon Musk recently posted on his site that another lawyer and I are “undermining civilization.” This is my response.
www.democracydocket.com
February 22, 2025 at 12:05 AM
I will use every tool at my disposal to protect this country from Trump. I will litigate to defend voting rights until there are no cases left to bring. I will speak out against authoritarianism until my last breath.
I will not back down. I will not bow or scrape. I will never obey.
I will not back down. I will not bow or scrape. I will never obey.
Reposted by TenaciousG
