The Lancet Neurology

@thelancetneuro.bsky.social

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The Lancet Neurology is the leading journal in clinical neurology. We publish articles and reviews that advocate change in, or illuminate, clinical practice.

🌐 https://www.thelancet.com/journals/laneur/home

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The Lancet Neurology @thelancetneuro.bsky.social · 1d

NEW ISSUE: Read the latest content on: Lewy bodies research, the global burden of headache disorders, brain amyloid and risk of cognitive impairment, biomarkers for multiple sclerosis, and more at:
thelancet.com/journals/lan...

The cover of the December 2025 issue of The Lancet Neurology, showing a head superimposed with lines, dots, and a digital countdown clock at zero. Cover image by Shonagh Rae

The Lancet Neurology @thelancetneuro.bsky.social · 1d

LISTEN: In the latest podcast episode, host Antonia Eisenkoeck speaks with Ian McKeith. They delve into the history of dementia with Lewy bodies research, highlighting key milestones and breakthroughs: www.buzzsprout.com/1391383/epis...

Ian McKeith on dementia with dementia with Lewy bodies - The Lancet Neurology in conversation with

In this episode, host Antonia Eisenkoeck, speaks with Ian McKeith, Emeritus Professor of Old Age Psychiatry at Newcastle University, UK. They delve into the history of dementia with Lewy bodies resear...

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The Lancet Neurology @thelancetneuro.bsky.social · 1d

SERIES: A collection of three papers highlight the latest advancements in basic and clinical research that are transforming the approach to disease management in Lewy body dementia: www.thelancet.com/series-do/de...

Advances in Dementia with Lewy Bodies

Lewy body dementia is a neurodegenerative disorder characterised by the accumulation of misfolded α-synuclein. The disease can disrupt cognitive function, motor function, autonomic regulation, and sle...

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The Lancet Neurology @thelancetneuro.bsky.social · 1d

In a Review, Tanuja Chitnis and colleagues provide an overview of the emerging evidence from studies that have assessed blood and CSF biomarkers and their clinical associations in patients with multiple sclerosis: thelancet.com/journals/lan...

Blood and CSF biomarkers for multiple sclerosis: emerging clinical applications

Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), chitinase-3-like protein 1 (CHI3L1), and other protein assays are being developed as diagnostic or prognostic biomarkers in mul...

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The Lancet Neurology @thelancetneuro.bsky.social · 1d

In their Article, Clifford Jack and colleagues compute lifetime and 10-year absolute risk of cognitive impairment as a function of continuous amyloid PET: thelancet.com/journals/lan...

Lifetime and 10-year absolute risk of cognitive impairment in relation to amyloid PET severity: a retrospective, longitudinal cohort study

Lifetime and 10-year absolute risk for MCI and dementia among individuals who are currently cognitively unimpaired increase with increasing biological severity of Alzheimer's disease. This information...

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The Lancet Neurology @thelancetneuro.bsky.social · 1d

The latest analysis of data from the Global Burden of Disease Study 2023 presents updated results on headache-attributed burden from 1990 to 2023, along with clinical and public health implications: thelancet.com/journals/lan...

Global, regional, and national burden of headache disorders, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Headache disorders, in particular migraine, continue to be a major global health challenge, emphasising the need for effective management and prevention strategies. Much headache-attributed burden cou...

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The Lancet @thelancet.com · 21d

"Politicians may forget...Communities do not."

In his latest Offline, Richard Horton reflects on the recent World Health Summit, where global health leaders grappled with the aftermath of the US' sudden withdrawal of funding from @who.int: tinyurl.com/mr3bjs85

Offline: “People have died”

The World Health Summit has proved itself the premier global health event of the year. Under the banner “Taking responsibility for health in a fragmenting world”—symbolised by a giant stage globe crac...

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The Lancet @thelancet.com · 21d

The UK is facing a pharma exodus, driven by claims that insufficient NHS investment threatens pharmaceutical innovation.

Yet, evidence suggests that the current pharma business model prioritises shareholder profits over innovation.

Find out more in an Editorial: tinyurl.com/n4pczpzx

Quote from the Lancet's Oct 25, 2025 Editorial. Quote reads: "The dysfunctionalities of the pharma business model will not be solved by ramping up drug prices."

The Lancet Neurology @thelancetneuro.bsky.social · 24d

Have you listened to our latest podcast on long-term stroke risk in women yet? Check it out here: thelancetneurology.buzzsprout.com

The Lancet Neurology in conversation with

Editors at The Lancet Neurology, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy.A monthly audio companion to...

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The Lancet @thelancet.com · 24d

📢 Call for papers 📢

There is still time to submit to our call for papers for a special issue on neurology. Deadline: Oct 31, 2025

Find out more 👉 tinyurl.com/4fwjttu2

Comment published in The Lancet entitled "Special issue on neurology: call for papers".

The Lancet Neurology @thelancetneuro.bsky.social · 28d

November issue live! Featuring a Series on intracranial aneurysms, Personal Views on issues related to Parkinson's disease, cutting-edge research on stroke risk, treatment for acute central retinal artery occlusion, & amyloid-related imaging abnormalities in Alzheimer's disease: tinyurl.com/4bt9bcjf

The Lancet Neurology, November 2025, Volume 24, Issue 11, Pages 893-986, e13

Explore the current issue of The Lancet Neurology, a monthly journal covering international issues relevant to neurologists worldwide

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The Lancet @thelancet.com · Oct 15

"...the outcomes of this work will be crucially important and will accelerate the path towards a treatment for every patient."

A new Comment discusses emerging opportunities through global collaboration for Parkinson's disease: tinyurl.com/mr3b49ex

Panel listing the aims of the Global Parkinson's Genetics Program (GP2). Copyright: 2025 Published by Elsevier Ltd.

The Lancet Neurology @thelancetneuro.bsky.social · Sep 27

'The quality of life of patients with dementia and their caregivers: important and yet inadequately assessed' - read our most recent InContext piece here:

The quality of life of patients with dementia and their caregivers: important and yet inadequately assessed

Dementia is one of the most pressing challenges for health and social care globally, with an estimated annual economic burden of £42 billion in the UK alone. The specific toll on individuals and…

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The Lancet Neurology @thelancetneuro.bsky.social · Sep 25

A new 3-part series on the new advances in Alzheimer's disease research has just been published by @thelancet.com. Check it out here: tinyurl.com/2ubpaap3

The Lancet Series on Alzheimer’s disease

The initial successes of anti-amyloid β monoclonal antibodies offer new perspectives for improving the clinical trajectory of Alzheimer’s disease for the first time since its identification in 1906.

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The Lancet Neurology @thelancetneuro.bsky.social · Sep 25

Online First: A Review on blood and CSF biomarkers for multiple sclerosis. Check it out: tinyurl.com/3v2s2ycr

Blood and CSF biomarkers for multiple sclerosis: emerging clinical applications

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Reposted by The Lancet Neurology, The Lancet Global Health

The Lancet @thelancet.com · Sep 24

Pledges have been made to tackle the growing burden of non-communicable diseases (NCDs) & mental health conditions—but financing has not followed.

Ahead of the #UNGA high-level meeting on NCDs, explore 7 key actions to improve financing & health outcomes: tinyurl.com/49vnsxad @lancetgh.bsky.social

Financing policies to sustain improved prevention, control, and management of non-communicable diseases and mental health conditions

All countries have pledged to tackle the growing burden of non-communicable diseases and mental health conditions, but financing has not followed. This Health Policy summarises the background research...

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The Lancet @thelancet.com · Sep 24

📢 Join our webinar on reporting race and ethnicity data in research

📆 Oct 23, 11am BST
👉 Register: hubs.li/Q03GrSg00

Our editors will guide you through our requirements for reporting race and ethnicity in your research, and share practical tips for all article types.

Join our webinar on reporting race and ethnicity data in research, taking place October 23, 2025. Copyright: Elsevier Ltd.

The Lancet Neurology @thelancetneuro.bsky.social · Sep 22

New Podcast Alert! 🎵 Listen to Shiv Saidha talking about recent updates in the diagnosis of multiple sclerosis:

Multimedia | Podcasts | In conversation with | The Lancet Neurology

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The Lancet Neurology @thelancetneuro.bsky.social · Sep 19

Online First: A Comment about the promises, hopes, and dreams of Parkinson's disease:

Promises, hopes, and dreams in Parkinson's disease research

Since James Parkinson first described his eponymous disease, our knowledge of its pathophysiology has grown enormously. However, in clinical settings, many of the original concepts remain in use, and…

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The Lancet Neurology @thelancetneuro.bsky.social · Sep 19

Our October issue is out - featuring biomarkers for sudden unexpected death in epilepsy, developments in the diagnosis of multiple sclerosis, climate change & brain health and much more!

Check it out here: tinyurl.com/3z5u36e7

#Neurology #BrainHealth

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The Lancet @thelancet.com · Sep 19

Non-communicable diseases (NCDs) include cancers, cardiovascular diseases, diabetes, immune disorders, and more.

What progress has been made in NCDs since the early 2000s?

In our latest issue, a new global analysis explores this question: tinyurl.com/mszsxer8

Full issue in thread 🧵

Cover of The Lancet's Sept 20, 2025 issue. Cover quote reads: "From 2010 to 2019, NCD mortality declined in four of every five countries in the world. These improvements were not as large as the preceding decade for most countries..."

The Lancet Neurology @thelancetneuro.bsky.social · Sep 18

The temporal order of genetic, environmental, and pathological risk factors in Parkinson's disease - read about it here: tinyurl.com/22uk86f8

The temporal order of genetic, environmental, and pathological risk factors in Parkinson's disease: paving the way to prevention

Genetics research in Parkinson's disease has identified over 100 risk loci, yet translating these findings into understanding of disease mechanisms, clinical and pathological heterogeneity, and diseas...

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The Lancet Neurology @thelancetneuro.bsky.social · Sep 9

If you haven't read it yet, we encourage you to check out this Review on the relevance of primary cilia in neurological disorders, featured in our most recent issue: tinyurl.com/2pdzssdv

#neurology #🧠

The relevance of primary cilia in neurological disorders

Primary cilia are ubiquitous organelles, which play essential roles in sensing and transducing cellular signals and in mediating key developmental pathways. Pathogenic variants in genes encoding for c...

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The Lancet @thelancet.com · Sep 9

"Who or what is responsible for a person risking their life to cross the Channel in a boat that is barely seaworthy?...All of us."

Richard Horton's latest Offline: Help us, please tinyurl.com/52zfck7b